2-chlorohexadecanal (BioDeep_00000629953)
代谢物信息卡片
2-chloropalmitaldehyde
化学式: C16H31ClO (274.2063306)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C(Cl)CCCCCCCCCCCCCC)(=O)[H]
InChI: InChI=1S/C16H31ClO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16(17)15-18/h15-16H,2-14H2,1H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jürgen Prasch, Eva Bernhart, Helga Reicher, Manfred Kollroser, Gerald N Rechberger, Chintan N Koyani, Christopher Trummer, Lavinia Rech, Peter P Rainer, Astrid Hammer, Ernst Malle, Wolfgang Sattler. Myeloperoxidase-Derived 2-Chlorohexadecanal Is Generated in Mouse Heart during Endotoxemia and Induces Modification of Distinct Cardiomyocyte Protein Subsets In Vitro.
International journal of molecular sciences.
2020 Dec; 21(23):. doi:
10.3390/ijms21239235. [PMID: 33287422] - Hong Yu, Meifang Wang, Derek Wang, Theodore J Kalogeris, Jane McHowat, David A Ford, Ronald J Korthuis. Chlorinated Lipids Elicit Inflammatory Responses in vitro and in vivo.
Shock (Augusta, Ga.).
2019 01; 51(1):114-122. doi:
10.1097/shk.0000000000001112. [PMID: 29394241] - Christoph Nusshold, Andreas Üllen, Nora Kogelnik, Eva Bernhart, Helga Reicher, Ioanna Plastira, Toma Glasnov, Klaus Zangger, Gerald Rechberger, Manfred Kollroser, Günter Fauler, Heimo Wolinski, Babette B Weksler, Ignacio A Romero, Sepp D Kohlwein, Pierre-Olivier Couraud, Ernst Malle, Wolfgang Sattler. Assessment of electrophile damage in a human brain endothelial cell line utilizing a clickable alkyne analog of 2-chlorohexadecanal.
Free radical biology & medicine.
2016 Jan; 90(?):59-74. doi:
10.1016/j.freeradbiomed.2015.11.010. [PMID: 26577177] - Mark A Duerr, Rajeev Aurora, David A Ford. Identification of glutathione adducts of α-chlorofatty aldehydes produced in activated neutrophils.
Journal of lipid research.
2015 May; 56(5):1014-24. doi:
10.1194/jlr.m058636. [PMID: 25814023] - Andreas Üllen, Christoph Nusshold, Toma Glasnov, Robert Saf, David Cantillo, Gerald Eibinger, Helga Reicher, Günter Fauler, Eva Bernhart, Seth Hallstrom, Nora Kogelnik, Klaus Zangger, C Oliver Kappe, Ernst Malle, Wolfgang Sattler. Covalent adduct formation between the plasmalogen-derived modification product 2-chlorohexadecanal and phloretin.
Biochemical pharmacology.
2015 Feb; 93(4):470-81. doi:
10.1016/j.bcp.2014.12.017. [PMID: 25576489] - Bradley K Wacker, Carolyn J Albert, Benjamin A Ford, David A Ford. Strategies for the analysis of chlorinated lipids in biological systems.
Free radical biology & medicine.
2013 Jun; 59(?):92-9. doi:
10.1016/j.freeradbiomed.2012.06.013. [PMID: 22713364] - William B Rizzo. The role of fatty aldehyde dehydrogenase in epidermal structure and function.
Dermato-endocrinology.
2011 Apr; 3(2):91-9. doi:
10.4161/derm.3.2.14619. [PMID: 21695018] - Viral V Brahmbhatt, Carolyn J Albert, Dhanalakshmi S Anbukumar, Bryce A Cunningham, William L Neumann, David A Ford. {Omega}-oxidation of {alpha}-chlorinated fatty acids: identification of {alpha}-chlorinated dicarboxylic acids.
The Journal of biological chemistry.
2010 Dec; 285(53):41255-69. doi:
10.1074/jbc.m110.147157. [PMID: 20956542] - Andreas Ullen, Günter Fauler, Harald Köfeler, Sabine Waltl, Christoph Nusshold, Eva Bernhart, Helga Reicher, Hans-Jörg Leis, Andrea Wintersperger, Ernst Malle, Wolfgang Sattler. Mouse brain plasmalogens are targets for hypochlorous acid-mediated modification in vitro and in vivo.
Free radical biology & medicine.
2010 Dec; 49(11):1655-65. doi:
10.1016/j.freeradbiomed.2010.08.025. [PMID: 20807565] - Dhanalakshmi S Anbukumar, Laurie P Shornick, Carolyn J Albert, Melissa M Steward, Raphael A Zoeller, William L Neumann, David A Ford. Chlorinated lipid species in activated human neutrophils: lipid metabolites of 2-chlorohexadecanal.
Journal of lipid research.
2010 May; 51(5):1085-92. doi:
10.1194/jlr.m003673. [PMID: 20019386] - Corinne M Spickett. Chlorinated lipids and fatty acids: an emerging role in pathology.
Pharmacology & therapeutics.
2007 Sep; 115(3):400-9. doi:
10.1016/j.pharmthera.2007.06.002. [PMID: 17658610] - Gunther Marsche, Regine Heller, Günter Fauler, Alenka Kovacevic, Alexander Nuszkowski, Wolfgang Graier, Wolfgang Sattler, Ernst Malle. 2-chlorohexadecanal derived from hypochlorite-modified high-density lipoprotein-associated plasmalogen is a natural inhibitor of endothelial nitric oxide biosynthesis.
Arteriosclerosis, thrombosis, and vascular biology.
2004 Dec; 24(12):2302-6. doi:
10.1161/01.atv.0000148703.43429.25. [PMID: 15514213] - Arun K Thukkani, Jane McHowat, Fong-Fu Hsu, Marie-Luise Brennan, Stanley L Hazen, David A Ford. Identification of alpha-chloro fatty aldehydes and unsaturated lysophosphatidylcholine molecular species in human atherosclerotic lesions.
Circulation.
2003 Dec; 108(25):3128-33. doi:
10.1161/01.cir.0000104564.01539.6a. [PMID: 14638540] - Arun K Thukkani, Carolyn J Albert, Kristin R Wildsmith, Maria C Messner, Bradley D Martinson, Fong-Fu Hsu, David A Ford. Myeloperoxidase-derived reactive chlorinating species from human monocytes target plasmalogens in low density lipoprotein.
The Journal of biological chemistry.
2003 Sep; 278(38):36365-72. doi:
10.1074/jbc.m305449200. [PMID: 12869568] - Carolyn J Albert, Jan R Crowley, Fong-Fu Hsu, Arun K Thukkani, David A Ford. Reactive brominating species produced by myeloperoxidase target the vinyl ether bond of plasmalogens: disparate utilization of sodium halides in the production of alpha-halo fatty aldehydes.
The Journal of biological chemistry.
2002 Feb; 277(7):4694-703. doi:
10.1074/jbc.m110875200. [PMID: 11836259] - C J Albert, J R Crowley, F F Hsu, A K Thukkani, D A Ford. Reactive chlorinating species produced by myeloperoxidase target the vinyl ether bond of plasmalogens: identification of 2-chlorohexadecanal.
The Journal of biological chemistry.
2001 Jun; 276(26):23733-41. doi:
10.1074/jbc.m101447200. [PMID: 11301330]