FA 8:2 (BioDeep_00000628836)

   


代谢物信息卡片


3‑(cyclo­pent-2-en-1-yl)-propa­noic acid

化学式: C8H12O2 (140.0837252)
中文名称: 2-辛炔酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C#CCCCCCC(=O)O
InChI: InChI=1S/C8H12O2/c1-2-3-4-5-6-7-8(9)10/h1H,3-7H2,(H,9,10)

描述信息

同义名列表

15 个代谢物同义名

3‑(cyclo­pent-2-en-1-yl)-propa­noic acid; 3-(2-cyclopenten-1-yl)-propanoic acid; Alepramic acid; Alepraic acid; FA 8:2; 2E,7-Octadienoic acid; C8:2n-1,6; 7-octynoic acid; Pentylpropiolic acid; 2-Octyn-1-oic acid; 2-octynoic acid; 5,7-octadienoic acid; C8:2n-1,3; 4Z,7-octadienoic acid; C8:2n-1,4



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Junyu Fan, Xiaojun Tang, Qian Wang, Zhuoya Zhang, Shufang Wu, Wenchao Li, Shanshan Liu, Genhong Yao, Hongwei Chen, Lingyun Sun. Mesenchymal stem cells alleviate experimental autoimmune cholangitis through immunosuppression and cytoprotective function mediated by galectin-9. Stem cell research & therapy. 2018 09; 9(1):237. doi: 10.1186/s13287-018-0979-x. [PMID: 30223894]
  • C-H Chang, Y-C Chen, Y-H Yu, M-H Tao, P S C Leung, A A Ansari, M E Gershwin, Y-H Chuang. Innate immunity drives xenobiotic-induced murine autoimmune cholangitis. Clinical and experimental immunology. 2014 Aug; 177(2):373-80. doi: 10.1111/cei.12298. [PMID: 24547942]
  • Amy Dhirapong, Guo-Xiang Yang, Steven Nadler, Weici Zhang, Koichi Tsuneyama, Patrick Leung, Stuart Knechtle, Aftab A Ansari, Ross L Coppel, Fu-Tong Liu, Xiao-Song He, M Eric Gershwin. Therapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosis. Hepatology (Baltimore, Md.). 2013 Feb; 57(2):708-15. doi: 10.1002/hep.26067. [PMID: 22996325]
  • Darong Yang, Binbin Xue, Xiaohong Wang, Xiaoyan Yu, Nianli Liu, Yimin Gao, Chen Liu, Haizhen Zhu. 2-octynoic acid inhibits hepatitis C virus infection through activation of AMP-activated protein kinase. PloS one. 2013; 8(5):e64932. doi: 10.1371/journal.pone.0064932. [PMID: 23741428]
  • S Shimoda, K Tsuneyama, K Kikuchi, K Harada, Y Nakanuma, M Nakamura, H Ishibashi, S Hisamoto, H Niiro, P S C Leung, A A Ansari, M E Gershwin, K Akashi. The role of natural killer (NK) and NK T cells in the loss of tolerance in murine primary biliary cirrhosis. Clinical and experimental immunology. 2012 Jun; 168(3):279-84. doi: 10.1111/j.1365-2249.2012.04581.x. [PMID: 22519590]
  • Phornnop Naiyanetr, Jeffrey D Butler, Liping Meng, Janice Pfeiff, Thomas P Kenny, Kathryn G Guggenheim, Roman Reiger, Kit Lam, Mark J Kurth, Aftab A Ansari, Ross L Coppel, Marcos López-Hoyos, M Eric Gershwin, Patrick S C Leung. Electrophile-modified lipoic derivatives of PDC-E2 elicits anti-mitochondrial antibody reactivity. Journal of autoimmunity. 2011 Nov; 37(3):209-16. doi: 10.1016/j.jaut.2011.06.001. [PMID: 21763105]
  • Y M Ambrosini, G-X Yang, W Zhang, M Tsuda, S Shu, K Tsuneyama, P S C Leung, A A Ansari, R L Coppel, M E Gershwin. The multi-hit hypothesis of primary biliary cirrhosis: polyinosinic-polycytidylic acid (poly I:C) and murine autoimmune cholangitis. Clinical and experimental immunology. 2011 Oct; 166(1):110-20. doi: 10.1111/j.1365-2249.2011.04453.x. [PMID: 21910728]
  • Simon Hohenester, Ronald P J Oude-Elferink, Ulrich Beuers. Primary biliary cirrhosis. Seminars in immunopathology. 2009 Sep; 31(3):283-307. doi: 10.1007/s00281-009-0164-5. [PMID: 19603170]
  • K Wakabayashi, K Yoshida, P S C Leung, Y Moritoki, G-X Yang, K Tsuneyama, Z-X Lian, T Hibi, A A Ansari, L S Wicker, W M Ridgway, R L Coppel, I R Mackay, M E Gershwin. Induction of autoimmune cholangitis in non-obese diabetic (NOD).1101 mice following a chemical xenobiotic immunization. Clinical and experimental immunology. 2009 Mar; 155(3):577-86. doi: 10.1111/j.1365-2249.2008.03837.x. [PMID: 19094117]
  • Kanji Wakabayashi, Zhe-Xiong Lian, Patrick S C Leung, Yuki Moritoki, Koichi Tsuneyama, Mark J Kurth, Kit S Lam, Katsunori Yoshida, Guo-Xiang Yang, Toshifumi Hibi, Aftab A Ansari, William M Ridgway, Ross L Coppel, Ian R Mackay, M Eric Gershwin. Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease. Hepatology (Baltimore, Md.). 2008 Aug; 48(2):531-40. doi: 10.1002/hep.22390. [PMID: 18563844]
  • Teru Kumagi, E Jenny Heathcote. Primary biliary cirrhosis. Orphanet journal of rare diseases. 2008 Jan; 3(?):1. doi: 10.1186/1750-1172-3-1. [PMID: 18215315]
  • J M Fletcher, J J Pitt. Pitfalls in the use of 2-octynoic acid as an in vivo model of medium-chain acyl-coenzyme A dehydrogenase deficiency: ketone turnover and metabolite studies in the rat. Metabolism: clinical and experimental. 1999 Jun; 48(6):685-8. doi: 10.1016/s0026-0495(99)90165-8. [PMID: 10381140]
  • J A Montgomery, O A Mamer, E Colle. Profiles in altered metabolism. IV--Induction of acute dicarboxylic aciduria following 2-octynoic acid administration to the rat. Biomedical & environmental mass spectrometry. 1989 Jun; 18(6):416-23. doi: 10.1002/bms.1200180610. [PMID: 2765701]
  • C G Birch, R A Hiles, T H Eichhold, A R Jeffcoat, R W Handy, J M Hill, S L Willis, T R Hess, M E Wall. Biotransformation products of 3,4,4'-trichlorocarbanilide in rat, monkey, and man. Drug metabolism and disposition: the biological fate of chemicals. 1978 Mar; 6(2):169-76. doi: NULL. [PMID: 26533]
  • O V Popov, R R Smiller. [State of glucocorticoid activity in patients with different histologic variants of Hodgkin's disease]. Problemy gematologii i perelivaniia krovi. 1977 Jan; 22(1):11-5. doi: NULL. [PMID: 834733]