FA 22:4 (BioDeep_00000628822)
LipidSearch
代谢物信息卡片
Z,Z,Z,Z-5,13,16,19-Docosatetraenoic acid
化学式: C22H36O2 (332.2715)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(lipidsearch) 96.93%
分子结构信息
SMILES: C(=C/C/C=C/CCCCCCCC)\C/C=C/C/C=C/CCC(=O)O
InChI: InChI=1S/C22H36O2/c23-20(24)9-7-5-3-1-2-4-6-8-15-10-11-18-19(14-15)22-17-13-12-16(17)21(18)22/h15-19,21-22H,1-14H2,(H,23,24)
描述信息
同义名列表
24 个代谢物同义名
Z,Z,Z,Z-5,13,16,19-Docosatetraenoic acid; Docosa-5c,13c,16c,19c-tetraenoic acid; 5Z,13Z,16Z,19Z-Docosatetraenoic acid; 5c,13c,16c,19c-Docosatetraenoic acid; FA 22:4; 4Z,7Z,10Z,13E-docosatetraenoic acid; 22:4(4Z,7Z,10Z,13E); 7Z,13Z,16Z,19Z-docosatetraenoic acid; 22:4(7Z,13Z,16Z,19Z); C22:4n-3,6,9,15; 7,10,13,16-docosatetraenoic acid; C22:4n-6,9,12,15; adrenic acid; 10-[3]-ladderane-decanoic acid; 10Z,13Z,16Z,19Z-docosatetraenoic acid; Lynenic acid; 4Z,9E,15E,19Z-docosatetraenoic acid; 5Z,8Z,11Z,14Z-docosatetraenoic acid; delta5,8,11,14-22:4; 8, 12, 16, 19 (20)-docosatetraenoic acid; 8,12,16,19-docosatetraenoic acid; C22:4n-3,6,10,14; 4,7,10,13-docosatetraenoic acid; C22:4n-9,12,15,18
数据库引用编号
24 个数据库交叉引用编号
- ChEBI: CHEBI:186667
- ChEBI: CHEBI:186616
- ChEBI: CHEBI:187931
- ChEBI: CHEBI:165486
- ChEBI: CHEBI:165467
- PubChem: 131840333
- PubChem: 21775584
- PubChem: 52922003
- PubChem: 5282844
- PubChem: 42607293
- PubChem: 102021030
- PubChem: 10759012
- PubChem: 5282845
- PubChem: 5282843
- LipidMAPS: LMFA04000087
- LipidMAPS: LMFA04000066
- LipidMAPS: LMFA04000063
- LipidMAPS: LMFA04000050
- LipidMAPS: LMFA01140012
- LipidMAPS: LMFA01031304
- LipidMAPS: LMFA01031212
- LipidMAPS: LMFA01031173
- LipidMAPS: LMFA01030179
- LipidMAPS: LMFA01030177
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Chia-Hsiu Wu, Wen-Li Hsu, Ching-Chung Tsai, How-Ran Chao, Ching-Ying Wu, Yi-Hsuan Chen, Yun-Ru Lai, Chu-Huang Chen, Ming-Hsien Tsai. 7,10,13,16-Docosatetraenoic acid impairs neurobehavioral development by increasing reactive oxidative species production in Caenorhabditis elegans.
Life sciences.
2023 Apr; 319(?):121500. doi:
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2021 09; 35(9):e21868. doi:
10.1096/fj.202100493rr. [PMID: 34449920] - Ji-Yoon Lee, Miso Nam, Hye Young Son, Kwangbeom Hyun, Seo Young Jang, Jong Woo Kim, Min Wook Kim, Youngae Jung, Eunji Jang, Seon-Jin Yoon, Jungeun Kim, Jihye Kim, Jinho Seo, Jeong-Ki Min, Kyoung-Jin Oh, Baek-Soo Han, Won Kon Kim, Kwang-Hee Bae, Jaewhan Song, Jaehoon Kim, Yong-Min Huh, Geum-Sook Hwang, Eun-Woo Lee, Sang Chul Lee. Polyunsaturated fatty acid biosynthesis pathway determines ferroptosis sensitivity in gastric cancer.
Proceedings of the National Academy of Sciences of the United States of America.
2020 12; 117(51):32433-32442. doi:
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International journal of molecular sciences.
2020 Nov; 21(22):. doi:
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2020 11; 34(11):15123-15145. doi:
10.1096/fj.202001344r. [PMID: 32931072] - Souha Hammouda, Imen Ghzaiel, Wided Khamlaoui, Sonia Hammami, Samia Younes Mhenni, Slim Samet, Mohamed Hammami, Amira Zarrouk. Genetic variants in FADS1 and ELOVL2 increase level of arachidonic acid and the risk of Alzheimer's disease in the Tunisian population.
Prostaglandins, leukotrienes, and essential fatty acids.
2020 09; 160(?):102159. doi:
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Free radical biology & medicine.
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2018 07; 17(7):2307-2317. doi:
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Toxicology.
2017 09; 390(?):124-134. doi:
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Archives of biochemistry and biophysics.
2017 06; 623-624(?):64-75. doi:
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Free radical research.
2017 Mar; 51(3):269-280. doi:
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Nature chemical biology.
2017 Jan; 13(1):81-90. doi:
10.1038/nchembio.2238. [PMID: 27842066] - Kunio Yui, George Imataka, Yohei Kawasak, Hiroshi Yamada. Increased ω-3 polyunsaturated fatty acid/arachidonic acid ratios and upregulation of signaling mediator in individuals with autism spectrum disorders.
Life sciences.
2016 Jan; 145(?):205-12. doi:
10.1016/j.lfs.2015.12.039. [PMID: 26724495] - Ming Long Sirius Chung, Jean-Marie Galano, Camille Oger, Thierry Durand, Jetty Chung-Yung Lee. Hyperoxia elevates adrenic acid peroxidation in marine fish and is associated with reproductive pheromone mediators.
Marine drugs.
2015 Apr; 13(4):2215-32. doi:
10.3390/md13042215. [PMID: 25874920] - Jean-Marie Galano, Jetty Chung-Yung Lee, Cecile Gladine, Blandine Comte, Jean-Yves Le Guennec, Camille Oger, Thierry Durand. Non-enzymatic cyclic oxygenated metabolites of adrenic, docosahexaenoic, eicosapentaenoic and α-linolenic acids; bioactivities and potential use as biomarkers.
Biochimica et biophysica acta.
2015 Apr; 1851(4):446-55. doi:
10.1016/j.bbalip.2014.11.004. [PMID: 25463478] - Aurélien de La Torre, Yiu Yiu Lee, Camille Oger, Per Torp Sangild, Thierry Durand, Jetty Chung-Yung Lee, Jean-Marie Galano. Synthesis, discovery, and quantitation of dihomo-isofurans: biomarkers for in vivo adrenic acid peroxidation.
Angewandte Chemie (International ed. in English).
2014 Jun; 53(24):6249-52. doi:
10.1002/anie.201402440. [PMID: 24839059] - Juliana S Vaz, Gilberto Kac, Antonio E Nardi, Joseph R Hibbeln. Omega-6 fatty acids and greater likelihood of suicide risk and major depression in early pregnancy.
Journal of affective disorders.
2014 Jan; 152-154(?):76-82. doi:
10.1016/j.jad.2013.04.045. [PMID: 23726775] - Thierry Durand, Claudio De Felice, Cinzia Signorini, Camille Oger, Valérie Bultel-Poncé, Alexandre Guy, Jean-Marie Galano, Silvia Leoncini, Lucia Ciccoli, Alessandra Pecorelli, Giuseppe Valacchi, Joussef Hayek. F(2)-Dihomo-isoprostanes and brain white matter damage in stage 1 Rett syndrome.
Biochimie.
2013 Jan; 95(1):86-90. doi:
10.1016/j.biochi.2012.09.017. [PMID: 23009927] - Claudio De Felice, Cinzia Signorini, Thierry Durand, Camille Oger, Alexandre Guy, Valérie Bultel-Poncé, Jean-Marie Galano, Lucia Ciccoli, Silvia Leoncini, Maurizio D'Esposito, Stefania Filosa, Alessandra Pecorelli, Giuseppe Valacchi, Joussef Hayek. F2-dihomo-isoprostanes as potential early biomarkers of lipid oxidative damage in Rett syndrome.
Journal of lipid research.
2011 Dec; 52(12):2287-2297. doi:
10.1194/jlr.p017798. [PMID: 21917727] - Songsri Kaewsuwan, Nantavan Bunyapraphatsara, David J Cove, Ralph S Quatrano, Pichit Chodok. High level production of adrenic acid in Physcomitrella patens using the algae Pavlova sp. Delta(5)-elongase gene.
Bioresource technology.
2010 Jun; 101(11):4081-8. doi:
10.1016/j.biortech.2009.12.138. [PMID: 20106658] - Mike VanRollins, Randall L Woltjer, Huiyong Yin, Jason D Morrow, Thomas J Montine. F2-dihomo-isoprostanes arise from free radical attack on adrenic acid.
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2008 May; 49(5):995-1005. doi:
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Prostaglandins, leukotrienes, and essential fatty acids.
2007 Mar; 76(3):165-72. doi:
10.1016/j.plefa.2007.01.001. [PMID: 17317131] - Elizabeth A Thomas, Jeffrey K Yao. Clozapine specifically alters the arachidonic acid pathway in mice lacking apolipoprotein D.
Schizophrenia research.
2007 Jan; 89(1-3):147-53. doi:
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Prostaglandins.
1992 Dec; 44(6):519-30. doi:
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