SB-366791 (BioDeep_00000624918)

   


代谢物信息卡片


N-(3-Methoxyphenyl)-4-chlorocinnamanilide

化学式: C16H14ClNO2 (287.0713014)
中文名称: 3-(4-氯苯基)-N-(3-甲氧基苯基)-2-丙烯酰胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=CC=CC(=C1)NC(=O)C=CC2=CC=C(C=C2)Cl
InChI: InChI=1S/C16H14ClNO2/c1-20-15-4-2-3-14(11-15)18-16(19)10-7-12-5-8-13(17)9-6-12/h2-11H,1H3,(H,18,19)/b10-7+

描述信息

同义名列表

3 个代谢物同义名

N-(3-Methoxyphenyl)-4-chlorocinnamanilide; SB-366791; SB 366791



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Amanda J Page, George Hatzinikolas, Andrew D Vincent, Paul Cavuoto, Gary A Wittert. The TRPV1 channel regulates glucose metabolism. American journal of physiology. Endocrinology and metabolism. 2019 10; 317(4):E667-E676. doi: 10.1152/ajpendo.00102.2019. [PMID: 31408376]
  • Sun Woo Jin, Yong Pil Hwang, Chul Yung Choi, Hyung Gyun Kim, Se Jong Kim, Yongan Kim, Young Chul Chung, Kyung Jin Lee, Tae Cheon Jeong, Hye Gwang Jeong. Protective effect of rutaecarpine against t-BHP-induced hepatotoxicity by upregulating antioxidant enzymes via the CaMKII-Akt and Nrf2/ARE pathways. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2017 Feb; 100(?):138-148. doi: 10.1016/j.fct.2016.12.031. [PMID: 28025122]
  • Dominika Labuz, Viola Spahn, Melih Özgür Celik, Halina Machelska. Opioids and TRPV1 in the peripheral control of neuropathic pain--Defining a target site in the injured nerve. Neuropharmacology. 2016 Feb; 101(?):330-40. doi: 10.1016/j.neuropharm.2015.10.003. [PMID: 26453963]
  • Carin Hoffmeister, Mariane Arnoldi Silva, Mateus Fortes Rossato, Gabriela Trevisan, Sara Marchesan Oliveira, Gustavo Petri Guerra, Cassia Regina Silva, Juliano Ferreira. Participation of the TRPV1 receptor in the development of acute gout attacks. Rheumatology (Oxford, England). 2014 Feb; 53(2):240-9. doi: 10.1093/rheumatology/ket352. [PMID: 24185761]
  • Daisy van Veghel, Jan Cleynhens, Larry V Pearce, Peter M Blumberg, Koen Van Laere, Alfons Verbruggen, Guy Bormans. Synthesis and biological evaluation of [¹¹C]SB366791: a new PET-radioligand for in vivo imaging of the TRPV1 receptor. Nuclear medicine and biology. 2013 Jan; 40(1):141-7. doi: 10.1016/j.nucmedbio.2012.08.011. [PMID: 23141549]
  • Sung-E Choi, Tae Ho Kim, Sang-A Yi, Yun Cheong Hwang, Won Sun Hwang, Sun Jung Choe, Seung Jin Han, Hae Jin Kim, Dae Jung Kim, Yup Kang, Kwan-Woo Lee. Capsaicin attenuates palmitate-induced expression of macrophage inflammatory protein 1 and interleukin 8 by increasing palmitate oxidation and reducing c-Jun activation in THP-1 (human acute monocytic leukemia cell) cells. Nutrition research (New York, N.Y.). 2011 Jun; 31(6):468-78. doi: 10.1016/j.nutres.2011.05.007. [PMID: 21745629]
  • Michelle Roche, John P Kelly, Maeve O'Driscoll, David P Finn. Augmentation of endogenous cannabinoid tone modulates lipopolysaccharide-induced alterations in circulating cytokine levels in rats. Immunology. 2008 Oct; 125(2):263-71. doi: 10.1111/j.1365-2567.2008.02838.x. [PMID: 18393970]
  • R Costa, D M Marotta, M N Manjavachi, E S Fernandes, J F Lima-Garcia, A F Paszcuk, N L M Quintão, L Juliano, S D Brain, J B Calixto. Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice. British journal of pharmacology. 2008 Jul; 154(5):1094-103. doi: 10.1038/bjp.2008.172. [PMID: 18454165]
  • Sigrid E Myrdal, Peter S Steyger. TRPV1 regulators mediate gentamicin penetration of cultured kidney cells. Hearing research. 2005 Jun; 204(1-2):170-82. doi: 10.1016/j.heares.2005.02.005. [PMID: 15925202]
  • M J Gunthorpe, H K Rami, J C Jerman, D Smart, C H Gill, E M Soffin, S Luis Hannan, S C Lappin, J Egerton, G D Smith, A Worby, L Howett, D Owen, S Nasir, C H Davies, M Thompson, P A Wyman, A D Randall, J B Davis. Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist. Neuropharmacology. 2004 Jan; 46(1):133-49. doi: 10.1016/s0028-3908(03)00305-8. [PMID: 14654105]
  • Giovanni Appendino, Selena Harrison, Luciano De Petrocellis, Nives Daddario, Federica Bianchi, Aniello Schiano Moriello, Marcello Trevisani, Francesca Benvenuti, Pierangelo Geppetti, Vincenzo Di Marzo. Halogenation of a capsaicin analogue leads to novel vanilloid TRPV1 receptor antagonists. British journal of pharmacology. 2003 Aug; 139(8):1417-24. doi: 10.1038/sj.bjp.0705387. [PMID: 12922928]