9-Methylxanthine (BioDeep_00000624760)
代谢物信息卡片
9-methyl-2,3,6,9-tetrahydro-1H-purine-2,6-dione
化学式: C6H6N4O2 (166.0490736)
中文名称: 9-甲基黄嘌呤
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN1C=NC2=C1NC(=O)NC2=O
InChI: InChI=1S/C6H6N4O2/c1-10-2-7-3-4(10)8-6(12)9-5(3)11/h2H,1H3,(H2,8,9,11,12)
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:137296
- PubChem: 70975
- Metlin: METLIN96280
- ChEMBL: CHEMBL114328
- CAS: 1198-33-0
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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European journal of clinical pharmacology.
2004 Mar; 60(1):17-21. doi:
10.1007/s00228-003-0718-8. [PMID: 14747882] - Mohammad H Boskabady, Batool Shirmohammadi, Parastoo Jandaghi, Sahar Kiani. Possible mechanism(s) for relaxant effect of aqueous and macerated extracts from Nigella sativa on tracheal chains of guinea pig.
BMC pharmacology.
2004 Feb; 4(?):3. doi:
10.1186/1471-2210-4-3. [PMID: 15070429] - R J Maughan, J Griffin. Caffeine ingestion and fluid balance: a review.
Journal of human nutrition and dietetics : the official journal of the British Dietetic Association.
2003 Dec; 16(6):411-20. doi:
10.1046/j.1365-277x.2003.00477.x. [PMID: 19774754] - Carla C A Cardoso, Ernani R Paviani, Lavínia A Cruz, Fátima C R Guma, Radovan Borojevic, Regina M Guaragna. Effect of pentoxifylline on arachidonic acid metabolism, neutral lipid synthesis and accumulation during induction of the lipocyte phenotype by retinol in murine hepatic stellate cell.
Molecular and cellular biochemistry.
2003 Dec; 254(1-2):37-46. doi:
10.1023/a:1027356412399. [PMID: 14674680] - A R Campos, A I S Barros, F A Santos, V S N Rao. Guarana (Paullinia cupana Mart.) offers protection against gastric lesions induced by ethanol and indomethacin in rats.
Phytotherapy research : PTR.
2003 Dec; 17(10):1199-202. doi:
10.1002/ptr.1212. [PMID: 14669256] - I S Oliveira-Junior, B V Pinheiro, I D C G Silva, R Salomão, R L Zollner, O S Beppu. Pentoxifylline decreases tumor necrosis factor and interleukin-1 during high tidal volume.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
2003 Oct; 36(10):1349-57. doi:
10.1590/s0100-879x2003001000011. [PMID: 14502367] - V Shukla, R P Gude. Amelioration of B16F10 melanoma cells induced oxidative stress in DBA/2 mice by pentoxifylline.
Journal of experimental & clinical cancer research : CR.
2003 Sep; 22(3):407-10. doi:
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The Journal of endocrinology.
2003 Jul; 178(1):101-9. doi:
10.1677/joe.0.1780101. [PMID: 12844341] - Vivek Shukla, Rajiv P Gude. Potentiation of lipid peroxidation in B16F10 and B16F1 melanoma cells by caffeine, a methylxanthine derivative: relationship to intracellular glutathione.
Chemotherapy.
2003 May; 49(1-2):71-5. doi:
10.1159/000069785. [PMID: 12714815] - Aydin Yagmurlu, M Emin Boleken, Dilek Ertoy, Murat Ozsan, I Haluk Gokcora, Huseyin Dindar. Preventive effect of pentoxifylline on renal scarring in rat model of pyelonephritis.
Urology.
2003 May; 61(5):1037-41. doi:
10.1016/s0090-4295(02)02428-7. [PMID: 12736043] - Jan Glogowski, Douglas R Danforth, Andrzej Ciereszko. Inhibition of alkaline phosphatase activity of boar semen by pentoxifylline, caffeine, and theophylline.
Journal of andrology.
2002 Nov; 23(6):783-92. doi:
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Journal of the American Society of Nephrology : JASN.
2002 Nov; 13(11):2723-9. doi:
10.1097/01.asn.0000025282.48298.7b. [PMID: 12397042] - I S Serin, B Ozçelik, T Bekyurek, F Ozturk, N Koc, Y Sahin. Effects of pentoxifylline in the prevention of ovarian hyperstimulation syndrome in a rabbit model.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.
2002 Oct; 16(5):355-9. doi:
10.1080/gye.16.5.355.359. [PMID: 12587528] - Marleny D A Saldaña, Carsten Zetzl, Rahoma S Mohamed, G Brunner. Extraction of methylxanthines from guaraná seeds, maté leaves, and cocoa beans using supercritical carbon dioxide and ethanol.
Journal of agricultural and food chemistry.
2002 Aug; 50(17):4820-6. doi:
10.1021/jf020128v. [PMID: 12166966] - K L Khanduja, R K Sangari, A Bhardwaj. Caffeine, quercetin and alizarin stimulate the exhalation of metabolic products of [14C]-N-nitrosodiethylamine in mice.
Indian journal of experimental biology.
2002 Jun; 40(6):739-44. doi:
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Immunobiology.
2002 Mar; 205(1):17-34. doi:
10.1078/0171-2985-00108. [PMID: 11999342] - C Raetsch, J D Jia, G Boigk, M Bauer, E G Hahn, E-O Riecken, D Schuppan. Pentoxifylline downregulates profibrogenic cytokines and procollagen I expression in rat secondary biliary fibrosis.
Gut.
2002 Feb; 50(2):241-7. doi:
10.1136/gut.50.2.241. [PMID: 11788567] - A Kakuyama, Y Sadzuka. Effect of methylxanthine derivatives on doxorubicin transport and antitumor activity.
Current drug metabolism.
2001 Dec; 2(4):379-95. doi:
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Journal of chromatography. B, Biomedical sciences and applications.
2001 Aug; 759(2):209-18. doi:
10.1016/s0378-4347(01)00251-1. [PMID: 11499474] - R P Gude, L G Menon, S G Rao. Effect of Caffeine, a xanthine derivative, in the inhibition of experimental lung metastasis induced by B16F10 melanoma cells.
Journal of experimental & clinical cancer research : CR.
2001 Jun; 20(2):287-92. doi:
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American journal of kidney diseases : the official journal of the National Kidney Foundation.
2001 Apr; 37(4):877-8. doi:
10.1016/s0272-6386(01)80144-x. [PMID: 11273893] - S Murray, A O Odupitan, B P Murray, A R Boobis, R J Edwards. Inhibition of human CYP1A2 activity in vitro by methylxanthines: potent competitive inhibition by 8-phenyltheophylline.
Xenobiotica; the fate of foreign compounds in biological systems.
2001 Mar; 31(3):135-51. doi:
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