Iopentol (BioDeep_00000624678)

   


代谢物信息卡片


1-N,3-N-bis(2,3-dihydroxypropyl)-5-[N-(2-hydroxy-3-methoxypropyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboximidic acid

化学式: C20H28I3N3O9 (834.8959768000001)
中文名称: 碘戊醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=O)N(CC(COC)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
InChI: InChI=1S/C20H28I3N3O9/c1-9(29)26(5-12(32)8-35-2)18-16(22)13(19(33)24-3-10(30)6-27)15(21)14(17(18)23)20(34)25-4-11(31)7-28/h10-12,27-28,30-32H,3-8H2,1-2H3,(H,24,33)(H,25,34)

描述信息

V - Various > V08 - Contrast media > V08A - X-ray contrast media, iodinated > V08AB - Watersoluble, nephrotropic, low osmolar x-ray contrast media
D006133 - Growth Substances > D010937 - Plant Growth Regulators > D014283 - Triiodobenzoic Acids

同义名列表

3 个代谢物同义名

5-[acetyl-(2-hydroxy-3-methoxypropyl)amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide; Iopentol; 1-N,3-N-bis(2,3-dihydroxypropyl)-5-[N-(2-hydroxy-3-methoxypropyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboximidic acid



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Liliana Alejandra Chicaíza-Becerra, Mario García-Molina, Óscar Gamboa. Cost-effectiveness of iso- versus low-osmolality contrast media in outpatients with high risk of contrast medium-induced nephropathy. Biomedica : revista del Instituto Nacional de Salud. 2012 Jun; 32(2):182-8. doi: NULL. [PMID: 23242291]
  • Shingo Hatakeyama, Akihiko Abe, Takehiro Suzuki, Yasuhiro Hashimoto, Takuya Koie, Tomihisa Funyu, Shigeru Satoh, Tomonori Habuchi, Chikara Ohyama, Shigeki Matsuo. Clearance and safety of the radiocontrast medium iopamidol in peritoneal dialysis patients. International journal of nephrology. 2011; 2011(?):657051. doi: 10.4061/2011/657051. [PMID: 22028966]
  • Elias Alexopoulos, Konstantinos Spargias, Stamatis Kyrzopoulos, Athanassios Manginas, Gregory Pavlides, Vassilis Voudris, Stamatios Lerakis, Dalton S McLean, Dennis V Cokkinos. Contrast-induced acute kidney injury in patients with renal dysfunction undergoing a coronary procedure and receiving non-ionic low-osmolar versus iso-osmolar contrast media. The American journal of the medical sciences. 2010 Jan; 339(1):25-30. doi: 10.1097/maj.0b013e3181c06e70. [PMID: 19996728]
  • P Rathsmann, G F Jacobs, R-D Müller. [Intravenous contrast medium application in elderly patients -- evaluation of Iopentol (Imagopaque 300)]. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. 2004 Dec; 176(12):1826-31. doi: 10.1055/s-2004-813474. [PMID: 15573295]
  • GianCarlo Marenzi, Antonio L Bartorelli, Gianfranco Lauri, Emilio Assanelli, Marco Grazi, Jeness Campodonico, Ivana Marana. Continuous veno-venous hemofiltration for the treatment of contrast-induced acute renal failure after percutaneous coronary interventions. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 2003 Jan; 58(1):59-64. doi: 10.1002/ccd.10373. [PMID: 12508197]
  • Volkmar Lufft, Linda Hoogestraat-Lufft, Lüder M Fels, Daniel Egbeyong-Baiyee, Christoph J Olbricht, Michael Galanski. Angiography for renal artery stenosis: no additional impairment of renal function by angioplasty. European radiology. 2002 Apr; 12(4):804-9. doi: 10.1007/s003300101075. [PMID: 11960230]
  • P V Sergeev, N K Sviridov, Iu A Poliaev, N L Shimanovskiĭ. [Diagnostic effectiveness and safety of currently available X-ray contrast media]. Vestnik rentgenologii i radiologii. 1999 Nov; ?(6):45-9. doi: NULL. [PMID: 10714233]
  • S Spitzer, W Münster, R Sternitzky, R Bach, F Jung. Influence of Iodixanol-270 and Iopentol-150 on the microcirculation in man: influence of viscosity on capillary perfusion. Clinical hemorheology and microcirculation. 1999; 20(1):49-55. doi: NULL. [PMID: 11185684]
  • M Mironidou, O Ximitidou, S Christopoulos, B Kokkas. The effect of some iodinated contrast media on human plasma butyrylcholinesterase activity. Investigative radiology. 1998 May; 33(5):308-10. doi: 10.1097/00004424-199805000-00008. [PMID: 9609490]
  • T Lehnert, E Keller, K Gondolf, T Schäffner, H Pavenstädt, P Schollmeyer. Effect of haemodialysis after contrast medium administration in patients with renal insufficiency. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 1998 Feb; 13(2):358-62. doi: 10.1093/oxfordjournals.ndt.a027830. [PMID: 9509446]
  • A Kruse, A Brock, J Rodenberg, E Nowakowska-Duawa, K Bjartveit. Iopentol (Imagopaque 250) compared with diatrizoate (Urografin 219) in endoscopic retrograde cholangio-pancreatography (ERCP). A clinical trial assessing safety (adverse events and S-pancreatic iso-amylase) and diagnostic information (VAS). European radiology. 1997; 7 Suppl 4(?):S131-4. doi: 10.1007/pl00006879. [PMID: 9204355]
  • D Rickards, J A Jakobsen, A J Klaveness, P Kjaersgaard. Delayed CT of the kidneys after iopentol (Imagopaque 350) injection in patients with normal renal function. An assessment of the gradual decrease in opacification over 32 h after injection. European radiology. 1997; 7 Suppl 4(?):S149-51. doi: 10.1007/pl00006883. [PMID: 9204359]
  • A Dick, G Adam, J Tacke, A Prescher, T E Southon, R W Günther. Computed tomography of experimental liver abscesses using a new liposomal contrast agent. Investigative radiology. 1996 Apr; 31(4):194-203. doi: 10.1097/00004424-199604000-00003. [PMID: 8721958]
  • M Carraro, W Mancini, M Artero, F Stacul, M Grotto, M Cova, L Faccini. Dose effect of nitrendipine on urinary enzymes and microproteins following non-ionic radiocontrast administration. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 1996 Mar; 11(3):444-8. doi: 10.1093/oxfordjournals.ndt.a027309. [PMID: 8671813]
  • J A Jakobsen. Renal experience with Visipaque. European radiology. 1996; 6 Suppl 2(?):S16-9. doi: 10.1007/bf02342567. [PMID: 8798051]
  • W Krause, D Niehues. Biochemical characterization of x-ray contrast media. Investigative radiology. 1996 Jan; 31(1):30-42. doi: 10.1097/00004424-199601000-00006. [PMID: 8850363]
  • G Stake, T Monclair, K J Berg, K Rootwelt, O Brekke. Effect of iopentol on renal function and its use for calculation of glomerular filtration rate in children. Acta radiologica (Stockholm, Sweden : 1987). 1995 Jan; 36(1):64-8. doi: NULL. [PMID: 7833171]
  • K Golman, B H Grynne. Nonionic dimer x-ray contrast media. Will they be of clinical benefit?. Investigative radiology. 1994 Jun; 29 Suppl 2(?):S230-1. doi: 10.1097/00004424-199406001-00077. [PMID: 7928240]
  • J A Jakobsen, K J Berg, U Brodahl, B Laake, A Moxness. Renal effects of nonionic contrast media after cardioangiography. Acta radiologica (Stockholm, Sweden : 1987). 1994 Mar; 35(2):191-6. doi: NULL. [PMID: 8172750]
  • T Nybonde, H Wahlgren, O Brekke, D T Kristofferssen, W Mortensson. Image quality and safety in pediatric urography using an ionic and a non-ionic iodinated contrast agent. Pediatric radiology. 1994; 24(2):107-10. doi: 10.1007/bf02020165. [PMID: 8078710]
  • J A Jakobsen, J O Nossen, N P Jørgensen, K J Berg. Renal tubular effects of diuretics and X-ray contrast media. A comparative study of equimolar doses in healthy volunteers. Investigative radiology. 1993 Apr; 28(4):319-24. doi: 10.1097/00004424-199304000-00012. [PMID: 8478172]
  • N P Jørgensen, J O Nossen, K W Borch, A B Kristiansen, D T Kristoffersen, B Lundby, L Theodorsen. Safety and tolerability of iodixanol in healthy volunteers with reference to two monomeric X-ray contrast media. European journal of radiology. 1992 Oct; 15(3):252-7. doi: 10.1016/0720-048x(92)90118-s. [PMID: 1490453]
  • M G Svaland, F Kolmannskog, P E Lillevold, K P Nordal, L Ressem, K J Berg. Pharmacokinetics of iopentol in patients with chronic renal failure. Acta radiologica (Stockholm, Sweden : 1987). 1992 Sep; 33(5):482-4. doi: NULL. [PMID: 1389660]
  • A T Andresen, P B Jacobsen, K E Rasmussen. Automated high-performance liquid chromatography of iopentol in human plasma and whole blood using on-line dialysis as sample preparation. Journal of chromatography. 1992 Mar; 575(1):93-9. doi: 10.1016/0378-4347(92)80508-n. [PMID: 1517306]
  • J A Jakobsen, B Lundby, D T Kristoffersen, K W Borch, J K Hald, K J Berg. Evaluation of renal function with delayed CT after injection of nonionic monomeric and dimeric contrast media in healthy volunteers. Radiology. 1992 Feb; 182(2):419-24. doi: 10.1148/radiology.182.2.1732960. [PMID: 1732960]
  • K J Berg, F Kolmannskog, P E Lillevold, K P Nordal, L Ressem, K Rootwelt, M G Svaland. Iopentol in patients with chronic renal failure: its effects on renal function and its use as glomerular filtration rate parameter. Scandinavian journal of clinical and laboratory investigation. 1992 Feb; 52(1):27-33. doi: 10.3109/00365519209085437. [PMID: 1594886]
  • F Laerum, A Stordahl, K E Solheim, J R Haugstvedt, H E Roald, K Skinningsrud. Intestinal follow-through examinations with iohexol and iopentol. Permeability alterations and efficacy in patients with small bowel obstruction. Investigative radiology. 1991 Nov; 26 Suppl 1(?):S177-81; discussion S185. doi: 10.1097/00004424-199111001-00060. [PMID: 1808121]
  • J A Jakobsen, A N Kolbenstvedt, K J Berg. Renal effects of iopentol and iohexol after intravenous injection. Acta radiologica (Stockholm, Sweden : 1987). 1991 Jul; 32(4):320-4. doi: NULL. [PMID: 1863505]
  • J A Jakobsen, A N Kolbenstvedt, K Levorstad, K J Berg, I Enge. Renal effects of nonionic contrast media after intravenous cardiac, and lumbar aortic injections. Investigative radiology. 1990 Sep; 25 Suppl 1(?):S135-6. doi: 10.1097/00004424-199009001-00062. [PMID: 2283233]
  • J A Jakobsen, K J Berg, A Waaler, E Andrew. Renal effects of the non-ionic contrast medium iopentol after intravenous injection in healthy volunteers. Acta radiologica (Stockholm, Sweden : 1987). 1990 Jan; 31(1):87-91. doi: NULL. [PMID: 2187515]
  • J A Jakobsen, T A Hagve, T Holager, A Waaler, T Haider, E Andrew, T Aakhus. Safety and toleration of the non-ionic contrast medium iopentol. An intravenous phase I trial. European journal of radiology. 1989 Nov; 9(4):203-7. doi: NULL. [PMID: 2591384]
  • E Andrew, A Waaler, J Jakobsen, T Holager, M Lambrechts, A Moxnes, E Kruger Hagen, T Bach-Gansmo. Clinical trial program for iopentol. A new nonionic ratio 3.0 contrast medium with emphasis on clinical phases I and II. Investigative radiology. 1988 Sep; 23 Suppl 1(?):S189-92. doi: 10.1097/00004424-198809001-00034. [PMID: 3058629]
  • A Aulie Michelet. Effects of intravascular contrast media on blood-brain barrier. Comparison between iothalamate, iohexol, iopentol and iodixanol. Acta radiologica (Stockholm, Sweden : 1987). 1987 May; 28(3):329-33. doi: NULL. [PMID: 2958041]
  • E Holtz, I F Heglund, K Golman. Albuminuria following nephroangiography with low osmolar contrast media in the rat. Acta radiologica. Supplementum. 1987; 370(?):57-9. doi: NULL. [PMID: 2980313]
  • K Skinnemoen, R Fagervoll, T Jacobsen. Determination of iopentol and other non-ionic contrast agents in biologic fluids by high-performance liquid chromatography. Acta radiologica. Supplementum. 1987; 370(?):23-5. doi: NULL. [PMID: 2980306]
  • A Waaler, N P Jørgensen, B Koksvik, K Skinnemoen, E Andrew. Pharmacokinetics of iopentol in healthy volunteers. Acta radiologica. Supplementum. 1987; 370(?):113-7. doi: NULL. [PMID: 2980304]
  • I Leunbach, K Skinnemoen, K Golman. Metabolism and excretion of iopentol in the pig. Acta radiologica. Supplementum. 1987; 370(?):105-7. doi: NULL. [PMID: 2980302]
  • A A Michelet, K Skinnemoen. Pharmacokinetics of iopentol in the rat. Acta radiologica. Supplementum. 1987; 370(?):101-4. doi: NULL. [PMID: 2980301]
  • T Aakhus, O Stokke, H Stormorken, K J Berg, K Dahlstrøm. Pharmacologic effects of iopentol after intravenous injection in healthy volunteers. Preliminary report. Acta radiologica. Supplementum. 1987; 370(?):109-12. doi: NULL. [PMID: 2980303]
  • E Holtz, K Golman. Experimental urography with new non-ionic dimeric and monomeric contrast agents. Acta radiologica. Supplementum. 1987; 370(?):49-55. doi: NULL. [PMID: 2980312]