8-Oxoguanine (BioDeep_00000624657)

   


代谢物信息卡片


6-hydroxy-2-imino-8,9-dihydro-2H-purin-8-one

化学式: C5H3N5O2 (165.0287)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C12=NC(=O)N=C1N=C(NC2=O)N
InChI: InChI=1S/C5H3N5O2/c6-4-8-2-1(3(11)10-4)7-5(12)9-2/h(H3,6,8,9,10,11,12)

描述信息

同义名列表

3 个代谢物同义名

8-Oxoguanine; 6-hydroxy-2-imino-8,9-dihydro-2H-purin-8-one; 2-Amino-1H-purine-6,8-dione



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(1)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • John R Mercer, Kelly Gray, Nichola Figg, Sheetal Kumar, Martin R Bennett. The methyl xanthine caffeine inhibits DNA damage signaling and reactive species and reduces atherosclerosis in ApoE(-/-) mice. Arteriosclerosis, thrombosis, and vascular biology. 2012 Oct; 32(10):2461-7. doi: 10.1161/atvbaha.112.251322. [PMID: 22859494]
  • Stéphanie Duclos, Pierre Aller, Pawel Jaruga, Miral Dizdaroglu, Susan S Wallace, Sylvie Doublié. Structural and biochemical studies of a plant formamidopyrimidine-DNA glycosylase reveal why eukaryotic Fpg glycosylases do not excise 8-oxoguanine. DNA repair. 2012 Sep; 11(9):714-25. doi: 10.1016/j.dnarep.2012.06.004. [PMID: 22789755]
  • Min Ni, Jinrong Qiu, Weiwei He, Xiaoning Wang. The functional Ser326Cys polymorphism in hOGG1 is associated with gastric cancer risk: evidence from 1180 cases and 2444 controls. European journal of gastroenterology & hepatology. 2012 Jun; 24(6):683-7. doi: 10.1097/meg.0b013e328351d1c0. [PMID: 22343785]
  • Shiuan-Chih Chen, Chun-Chieh Chen, Chung-Yih Kuo, Chun-Huang Huang, Chin-Hsiu Lin, Zi-Yun Lu, Yi-Yu Chen, Hong-Shen Lee, Ruey-Hong Wong. Elevated risk of hypertension induced by arsenic exposure in Taiwanese rural residents: possible effects of manganese superoxide dismutase (MnSOD) and 8-oxoguanine DNA glycosylase (OGG1) genes. Archives of toxicology. 2012 Jun; 86(6):869-78. doi: 10.1007/s00204-011-0797-8. [PMID: 22193621]
  • Wei Gan, Ben Nie, Fei Shi, Xin-Min Xu, Jian-Chang Qian, Yasumitsu Takagi, Hiroshi Hayakawa, Mutsuo Sekiguchi, Jian-Ping Cai. Age-dependent increases in the oxidative damage of DNA, RNA, and their metabolites in normal and senescence-accelerated mice analyzed by LC-MS/MS: urinary 8-oxoguanosine as a novel biomarker of aging. Free radical biology & medicine. 2012 May; 52(9):1700-7. doi: 10.1016/j.freeradbiomed.2012.02.016. [PMID: 22348977]
  • Krzysztof Roszkowski, Ryszard Olinski. Urinary 8-oxoguanine as a predictor of survival in patients undergoing radiotherapy. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2012 Apr; 21(4):629-34. doi: 10.1158/1055-9965.epi-11-0981. [PMID: 22301827]
  • Paola Brun, Paola Brun, Maria Vono, Paola Venier, Elena Tarricone, Velika Deligianni, Emilio Martines, Matteo Zuin, Silvia Spagnolo, Roberto Cavazzana, Romilda Cardin, Ignazio Castagliuolo, Alvise La Gloria Valerio, Andrea Leonardi. Disinfection of ocular cells and tissues by atmospheric-pressure cold plasma. PloS one. 2012; 7(3):e33245. doi: 10.1371/journal.pone.0033245. [PMID: 22432007]
  • Mohammad Rezaee, Elahe Alizadeh, Darel Hunting, Léon Sanche. DNA-Platinum Thin Films for Use in Chemoradiation Therapy Studies. Bioinorganic chemistry and applications. 2012; 2012(?):923914. doi: 10.1155/2012/923914. [PMID: 21977010]
  • Larysa V Yuzefovych, Viktoriya A Solodushko, Glenn L Wilson, Lyudmila I Rachek. Protection from palmitate-induced mitochondrial DNA damage prevents from mitochondrial oxidative stress, mitochondrial dysfunction, apoptosis, and impaired insulin signaling in rat L6 skeletal muscle cells. Endocrinology. 2012 Jan; 153(1):92-100. doi: 10.1210/en.2011-1442. [PMID: 22128025]
  • Zhenming Cai, Huimei Chen, Jing Tao, Wenwen Guo, Xiufang Liu, Bixia Zheng, Wei Sun, Yaping Wang. Association of base excision repair gene polymorphisms with ESRD risk in a Chinese population. Oxidative medicine and cellular longevity. 2012; 2012(?):928421. doi: 10.1155/2012/928421. [PMID: 22720119]
  • Steffen Loft, Peter Svoboda, Kazuaki Kawai, Hiroshi Kasai, Mette Sørensen, Anne Tjønneland, Ulla Vogel, Peter Møller, Kim Overvad, Ole Raaschou-Nielsen. Association between 8-oxo-7,8-dihydroguanine excretion and risk of lung cancer in a prospective study. Free radical biology & medicine. 2012 Jan; 52(1):167-72. doi: 10.1016/j.freeradbiomed.2011.10.439. [PMID: 22044660]
  • Ji-Hua Nie, Zhi-Hai Chen, Xing Liu, Yan-Wen Wu, Ji-Xiang Li, Yi Cao, Tom K Hei, Jian Tong. Oxidative damage in various tissues of rats exposed to radon. Journal of toxicology and environmental health. Part A. 2012; 75(12):694-9. doi: 10.1080/15287394.2012.690086. [PMID: 22757673]
  • Mohamed Abdouh, Wassim Chatoo, Jida El Hajjar, Jocelyn David, José Ferreira, Gilbert Bernier. Bmi1 is down-regulated in the aging brain and displays antioxidant and protective activities in neurons. PloS one. 2012; 7(2):e31870. doi: 10.1371/journal.pone.0031870. [PMID: 22384090]
  • Marek Banasik, Todd Stedeford, Robert P Strosznajder, Masanori Takehashi, Seigo Tanaka, Kunihiro Ueda. Inhibition of poly(ADP-ribose) polymerase-1 attenuates the toxicity of carbon tetrachloride. Journal of enzyme inhibition and medicinal chemistry. 2011 Dec; 26(6):883-9. doi: 10.3109/14756366.2011.557315. [PMID: 21395487]
  • Nicole Berdelle, Teodora Nikolova, Steve Quiros, Thomas Efferth, Bernd Kaina. Artesunate induces oxidative DNA damage, sustained DNA double-strand breaks, and the ATM/ATR damage response in cancer cells. Molecular cancer therapeutics. 2011 Dec; 10(12):2224-33. doi: 10.1158/1535-7163.mct-11-0534. [PMID: 21998290]
  • Joshua M Chouteau, Boniface Obiako, Olena M Gorodnya, Viktor M Pastukh, Mykhaylo V Ruchko, Anthony J Wright, Glenn L Wilson, Mark N Gillespie. Mitochondrial DNA integrity may be a determinant of endothelial barrier properties in oxidant-challenged rat lungs. American journal of physiology. Lung cellular and molecular physiology. 2011 Dec; 301(6):L892-8. doi: 10.1152/ajplung.00210.2011. [PMID: 21890512]
  • Hoon Kim, Seung-Yup Ku, Jong Won Kang, Heon Kim, Yong Dae Kim, Seok Hyun Kim, Young Min Choi, Jung Gu Kim, Shin Yong Moon. The 8-hydroxydeoxyguanosine concentrations according to hormone therapy and S326C polymorphism of OGG1 gene in postmenopausal women. Molecular genetics and metabolism. 2011 Dec; 104(4):644-7. doi: 10.1016/j.ymgme.2011.08.016. [PMID: 21908221]
  • Ayse Basak Engin, Bensu Karahalil, Atilla Engin, Ali Esat Karakaya. DNA repair enzyme polymorphisms and oxidative stress in a Turkish population with gastric carcinoma. Molecular biology reports. 2011 Nov; 38(8):5379-86. doi: 10.1007/s11033-011-0690-9. [PMID: 21390502]
  • Jürgen Pauluhn, Martin Wiemann. Siderite (FeCO₃) and magnetite (Fe₃O₄) overload-dependent pulmonary toxicity is determined by the poorly soluble particle not the iron content. Inhalation toxicology. 2011 Nov; 23(13):763-83. doi: 10.3109/08958378.2011.606431. [PMID: 22035119]
  • Junko Fujihara, Mikiko Soejima, Toshihiro Yasuda, Yoshiro Koda, Takashi Kunito, Hisato Iwata, Shinsuke Tanabe, Haruo Takeshita. Polymorphic trial in oxidative damage of arsenic exposed Vietnamese. Toxicology and applied pharmacology. 2011 Oct; 256(2):174-8. doi: 10.1016/j.taap.2011.08.007. [PMID: 21864556]
  • Birgitta Grundmark, Björn Zethelius, Hans Garmo, Lars Holmberg. Serum levels of selenium and smoking habits at age 50 influence long term prostate cancer risk; a 34 year ULSAM follow-up. BMC cancer. 2011 Oct; 11(?):431. doi: 10.1186/1471-2407-11-431. [PMID: 21982398]
  • Glen E Kisby, Peter S Spencer. Is neurodegenerative disease a long-latency response to early-life genotoxin exposure?. International journal of environmental research and public health. 2011 10; 8(10):3889-921. doi: 10.3390/ijerph8103889. [PMID: 22073019]
  • Lukáš Pácal, Jana Varvařovská, Zdeněk Rušavý, Silva Lacigová, Rudolf Stětina, Jaroslav Racek, Renata Pomahačová, Veronika Tanhäuserová, Kateřina Kaňková. Parameters of oxidative stress, DNA damage and DNA repair in type 1 and type 2 diabetes mellitus. Archives of physiology and biochemistry. 2011 Oct; 117(4):222-30. doi: 10.3109/13813455.2010.551135. [PMID: 21338322]
  • S Mousavi, M Abdollahi, A Ahmadi, A Najafi, M Pazouki, M Hadjibabaie, S Ziaee, H Hamishehkar, A Kebriaeezadeh, M Mojtahedzadeh. The dilemma of hyperoxia following positive pressure mechanical ventilation: role of iron and the benefit of iron chelation with deferasirox. European review for medical and pharmacological sciences. 2011 Oct; 15(10):1141-8. doi: NULL. [PMID: 22165674]
  • Anca Macovei, Alma Balestrazzi, Massimo Confalonieri, Matteo Faé, Daniela Carbonera. New insights on the barrel medic MtOGG1 and MtFPG functions in relation to oxidative stress response in planta and during seed imbibition. Plant physiology and biochemistry : PPB. 2011 Sep; 49(9):1040-50. doi: 10.1016/j.plaphy.2011.05.007. [PMID: 21696973]
  • Kashyap B Choksi, Jonathan E Nuss, James H DeFord, John Papaconstantinou. Mitochondrial electron transport chain functions in long-lived Ames dwarf mice. Aging. 2011 Aug; 3(8):754-67. doi: 10.18632/aging.100357. [PMID: 21934186]
  • Zsolt Radak, Zhongfu Zhao, Sataro Goto, Erika Koltai. Age-associated neurodegeneration and oxidative damage to lipids, proteins and DNA. Molecular aspects of medicine. 2011 Aug; 32(4-6):305-15. doi: 10.1016/j.mam.2011.10.010. [PMID: 22020115]
  • Bin Xia, Jianwei Chen, Yikai Zhou. Cellular oxidative damage of HEK293T cells induced by combination of CdCl(2) and nano-TiO (2). Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. 2011 Jun; 31(3):290-294. doi: 10.1007/s11596-011-0369-4. [PMID: 21671166]
  • Mykhaylo V Ruchko, Olena M Gorodnya, Andres Zuleta, Viktor M Pastukh, Mark N Gillespie. The DNA glycosylase Ogg1 defends against oxidant-induced mtDNA damage and apoptosis in pulmonary artery endothelial cells. Free radical biology & medicine. 2011 May; 50(9):1107-13. doi: 10.1016/j.freeradbiomed.2010.10.692. [PMID: 20969951]
  • Hu Zhao, Chao Qin, Fu Yan, Bin Wu, Qiang Cao, Meilin Wang, Zhengdong Zhang, Changjun Yin. hOGG1 Ser326Cys polymorphism and renal cell carcinoma risk in a Chinese population. DNA and cell biology. 2011 May; 30(5):317-21. doi: 10.1089/dna.2010.1135. [PMID: 21166493]
  • Nady Braidy, Gilles J Guillemin, Hussein Mansour, Tailoi Chan-Ling, Anne Poljak, Ross Grant. Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats. PloS one. 2011 Apr; 6(4):e19194. doi: 10.1371/journal.pone.0019194. [PMID: 21541336]
  • Nassira Zribi, Nozha Feki Chakroun, Henda Elleuch, Fatma Ben Abdallah, Afifa Sellami Ben Hamida, Jalel Gargouri, Faiza Fakhfakh, Leila Ammar Keskes. Sperm DNA fragmentation and oxidation are independent of malondialdheyde. Reproductive biology and endocrinology : RB&E. 2011 Apr; 9(?):47. doi: 10.1186/1477-7827-9-47. [PMID: 21492479]
  • Hamzeh Al Zabadi, Luc Ferrari, Irène Sari-Minodier, Marie-Aude Kerautret, Aziz Tiberguent, Christophe Paris, Denis Zmirou-Navier. Integrated exposure assessment of sewage workers to genotoxicants: an urinary biomarker approach and oxidative stress evaluation. Environmental health : a global access science source. 2011 Mar; 10(?):23. doi: 10.1186/1476-069x-10-23. [PMID: 21435260]
  • Stephanie R Bollmann, Colin M Tominey, Peter D Hoffman, Taylor M C Hoffman, John B Hays. Reversion-reporter transgenes to analyze all six base-substitution pathways in Arabidopsis. Plant physiology. 2011 Mar; 155(3):1286-300. doi: 10.1104/pp.110.167726. [PMID: 21212302]
  • Sultan Ahmed, Sultana Mahabbat-e Khoda, Rokeya Sultana Rekha, Renee M Gardner, Syeda Shegufta Ameer, Sophie Moore, Eva-Charlotte Ekström, Marie Vahter, Rubhana Raqib. Arsenic-associated oxidative stress, inflammation, and immune disruption in human placenta and cord blood. Environmental health perspectives. 2011 Feb; 119(2):258-64. doi: 10.1289/ehp.1002086. [PMID: 20940111]
  • Anders Joergensen, Kasper Broedbaek, Allan Weimann, Richard D Semba, Luigi Ferrucci, Martin B Joergensen, Henrik E Poulsen. Association between urinary excretion of cortisol and markers of oxidatively damaged DNA and RNA in humans. PloS one. 2011; 6(6):e20795. doi: 10.1371/journal.pone.0020795. [PMID: 21687734]
  • M Marin-Kuan, V Ehrlich, T Delatour, C Cavin, B Schilter. Evidence for a role of oxidative stress in the carcinogenicity of ochratoxin a. Journal of toxicology. 2011; 2011(?):645361. doi: 10.1155/2011/645361. [PMID: 21776264]
  • Ana Lena Fidantsef, Anne Bagg Britt. Preferential repair of the transcribed DNA strand in plants. Frontiers in plant science. 2011; 2(?):105. doi: 10.3389/fpls.2011.00105. [PMID: 22629267]
  • Claire M Payne, Cheray Crowley-Skillicorn, Carol Bernstein, Hana Holubec, Harris Bernstein. Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis. Clinical and experimental gastroenterology. 2011; 4(?):75-119. doi: 10.2147/ceg.s17114. [PMID: 21753893]
  • Simon Wan Chan, Peter C Dedon. The biological and metabolic fates of endogenous DNA damage products. Journal of nucleic acids. 2010 Dec; 2010(?):929047. doi: 10.4061/2010/929047. [PMID: 21209721]
  • Stéphanie Lagadu, Mathilde Lechevrel, François Sichel, Jean Breton, Didier Pottier, Rémy Couderc, Fathi Moussa, Virginie Prevost. 8-oxo-7,8-dihydro-2'-deoxyguanosine as a biomarker of oxidative damage in oesophageal cancer patients: lack of association with antioxidant vitamins and polymorphism of hOGG1 and GST. Journal of experimental & clinical cancer research : CR. 2010 Dec; 29(?):157. doi: 10.1186/1756-9966-29-157. [PMID: 21134244]
  • Manolis Kogevinas, Cristina M Villanueva, Laia Font-Ribera, Danae Liviac, Mariona Bustamante, Felicidad Espinoza, Mark J Nieuwenhuijsen, Aina Espinosa, Pilar Fernandez, David M DeMarini, Joan O Grimalt, Tamara Grummt, Ricard Marcos. Genotoxic effects in swimmers exposed to disinfection by-products in indoor swimming pools. Environmental health perspectives. 2010 Nov; 118(11):1531-7. doi: 10.1289/ehp.1001959. [PMID: 20833606]
  • Tomasz Obtulowicz, Maja Swoboda, Elzbieta Speina, Daniel Gackowski, Rafal Rozalski, Agnieszka Siomek, Justyna Janik, Beata Janowska, Jaroslaw M Ciesla, Arkadiusz Jawien, Zbigniew Banaszkiewicz, Jolanta Guz, Tomasz Dziaman, Anna Szpila, Ryszard Olinski, Barbara Tudek. Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients. Mutagenesis. 2010 Sep; 25(5):463-71. doi: 10.1093/mutage/geq028. [PMID: 20534734]
  • Randa A El-Zein, Claudia M Monroy, Andrea Cortes, Margaret R Spitz, Anthony Greisinger, Carol J Etzel. Rapid method for determination of DNA repair capacity in human peripheral blood lymphocytes amongst smokers. BMC cancer. 2010 Aug; 10(?):439. doi: 10.1186/1471-2407-10-439. [PMID: 20718982]
  • Peter Møller, Steffen Loft. Oxidative damage to DNA and lipids as biomarkers of exposure to air pollution. Environmental health perspectives. 2010 Aug; 118(8):1126-36. doi: 10.1289/ehp.0901725. [PMID: 20423813]
  • Rame Taha, Ernest Seidman, Genevieve Mailhot, François Boudreau, Fernand-Pierre Gendron, Jean-François Beaulieu, Daniel Ménard, Edgard Delvin, Devendra Amre, Emile Levy. Oxidative stress and mitochondrial functions in the intestinal Caco-2/15 cell line. PloS one. 2010 Jul; 5(7):e11817. doi: 10.1371/journal.pone.0011817. [PMID: 20676402]
  • Leonardo S Vidal, Adriana M Alves, Ricardo M Kuster, Claudia Lage, Alvaro C Leitão. Genotoxicity and mutagenicity of Echinodorus macrophyllus (chapéu-de-couro) extracts. Genetics and molecular biology. 2010 Jul; 33(3):549-57. doi: 10.1590/s1415-47572010005000060. [PMID: 21637431]
  • Valentina Bollati, Barbara Marinelli, Pietro Apostoli, Matteo Bonzini, Francesco Nordio, Mirjam Hoxha, Valeria Pegoraro, Valeria Motta, Letizia Tarantini, Laura Cantone, Joel Schwartz, Pier Alberto Bertazzi, Andrea Baccarelli. Exposure to metal-rich particulate matter modifies the expression of candidate microRNAs in peripheral blood leukocytes. Environmental health perspectives. 2010 Jun; 118(6):763-8. doi: 10.1289/ehp.0901300. [PMID: 20061215]
  • Barbara Tudek, Alicja Winczura, Justyna Janik, Agnieszka Siomek, Marek Foksinski, Ryszard Oliński. Involvement of oxidatively damaged DNA and repair in cancer development and aging. American journal of translational research. 2010 May; 2(3):254-84. doi: ". [PMID: 20589166]
  • H Sova, A Jukkola-Vuorinen, U Puistola, S Kauppila, P Karihtala. 8-Hydroxydeoxyguanosine: a new potential independent prognostic factor in breast cancer. British journal of cancer. 2010 Mar; 102(6):1018-23. doi: 10.1038/sj.bjc.6605565. [PMID: 20179711]
  • John Mach, Adrian W Midgley, Steve Dank, Ross S Grant, David J Bentley. The effect of antioxidant supplementation on fatigue during exercise: potential role for NAD+(H). Nutrients. 2010 03; 2(3):319-29. doi: 10.3390/nu2030319. [PMID: 22254024]
  • Ryouhei Yoshihara, Yoshihiro Hase, Ryohei Sato, Koichi Takimoto, Issay Narumi. Mutational effects of different LET radiations in rpsL transgenic Arabidopsis. International journal of radiation biology. 2010 Feb; 86(2):125-31. doi: 10.3109/09553000903336826. [PMID: 20148698]
  • Krishna Vanaja Donkena, Charles Y F Young, Donald J Tindall. Oxidative stress and DNA methylation in prostate cancer. Obstetrics and gynecology international. 2010; 2010(?):302051. doi: 10.1155/2010/302051. [PMID: 20671914]
  • Xiaofei Gao, Fengyi Wan, Kristina Mateo, Eduardo Callegari, Dan Wang, Wanyin Deng, Jose Puente, Feng Li, Michael S Chaussee, B Brett Finlay, Michael J Lenardo, Philip R Hardwidge. Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function. PLoS pathogens. 2009 Dec; 5(12):e1000708. doi: 10.1371/journal.ppat.1000708. [PMID: 20041225]
  • J Y Ro, D Y Kim, S-H Lee, J W Park, M-H Chung. Effects of 7,8-dihydro-8-oxo-deoxyguanosine on antigen challenge in ovalbumin-sensitized mice may be mediated by suppression of Rac. British journal of pharmacology. 2009 Dec; 158(7):1743-52. doi: 10.1111/j.1476-5381.2009.00436.x. [PMID: 19845673]
  • Mohamed M A E L Salem, Mohammad Shalbaf, Nicholas C J Gibbons, Bhaven Chavan, J M Thornton, Karin U Schallreuter. Enhanced DNA binding capacity on up-regulated epidermal wild-type p53 in vitiligo by H2O2-mediated oxidation: a possible repair mechanism for DNA damage. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2009 Nov; 23(11):3790-807. doi: 10.1096/fj.09-132621. [PMID: 19641144]
  • Marcus S Cooke, Paul T Henderson, Mark D Evans. Sources of extracellular, oxidatively-modified DNA lesions: implications for their measurement in urine. Journal of clinical biochemistry and nutrition. 2009 Nov; 45(3):255-70. doi: 10.3164/jcbn.sr09-41. [PMID: 19902015]
  • Dolores Córdoba-Cañero, Teresa Morales-Ruiz, Teresa Roldán-Arjona, Rafael R Ariza. Single-nucleotide and long-patch base excision repair of DNA damage in plants. The Plant journal : for cell and molecular biology. 2009 Nov; 60(4):716-28. doi: 10.1111/j.1365-313x.2009.03994.x. [PMID: 19682284]
  • Zoreh Davanipour, Henrik E Poulsen, Allan Weimann, Eugene Sobel. Endogenous melatonin and oxidatively damaged guanine in DNA. BMC endocrine disorders. 2009 Oct; 9(?):22. doi: 10.1186/1472-6823-9-22. [PMID: 19835624]
  • Paola Manini, Giuseppe De Palma, Roberta Andreoli, Boleslaw Marczynski, Monika Hanova, Paola Mozzoni, Alessio Naccarati, Ludmila Vodickova, Pavel Hlavac, Antonio Mutti, Pavel Vodicka. Biomarkers of nucleic acid oxidation, polymorphism in, and expression of, hOGG1 gene in styrene-exposed workers. Toxicology letters. 2009 Oct; 190(1):41-7. doi: 10.1016/j.toxlet.2009.06.862. [PMID: 19563869]
  • T Shpitzer, Y Hamzany, G Bahar, R Feinmesser, D Savulescu, I Borovoi, M Gavish, R M Nagler. Salivary analysis of oral cancer biomarkers. British journal of cancer. 2009 Oct; 101(7):1194-8. doi: 10.1038/sj.bjc.6605290. [PMID: 19789535]
  • Kyota Fujita, Toshihiro Seike, Noriko Yutsudo, Mizuki Ohno, Hidetaka Yamada, Hiroo Yamaguchi, Kunihiko Sakumi, Yukiko Yamakawa, Mizuho A Kido, Atsushi Takaki, Toshihiko Katafuchi, Yoshinori Tanaka, Yusaku Nakabeppu, Mami Noda. Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. PloS one. 2009 Sep; 4(9):e7247. doi: 10.1371/journal.pone.0007247. [PMID: 19789628]
  • Takeshi Hirano, Akinori Sakai, Yuko Ootsuyama, Hiroshi Kasai. Chronic alcohol consumption prevents 8-hydroxyguanine accumulation in 3'-methyl-4-dimethylaminoazobenzene-treated mouse liver. Biochemical and biophysical research communications. 2009 Sep; 387(2):316-20. doi: 10.1016/j.bbrc.2009.07.016. [PMID: 19596271]
  • David J Studholme, Selena Gimenez Ibanez, Daniel MacLean, Jeffery L Dangl, Jeff H Chang, John P Rathjen. A draft genome sequence and functional screen reveals the repertoire of type III secreted proteins of Pseudomonas syringae pathovar tabaci 11528. BMC genomics. 2009 Aug; 10(?):395. doi: 10.1186/1471-2164-10-395. [PMID: 19703286]
  • Marika Crohns, Seppo Saarelainen, Marina Erhola, Hannu Alho, Pirkko Kellokumpu-Lehtinen. Impact of radiotherapy and chemotherapy on biomarkers of oxidative DNA damage in lung cancer patients. Clinical biochemistry. 2009 Jul; 42(10-11):1082-90. doi: 10.1016/j.clinbiochem.2009.02.022. [PMID: 19272366]
  • Scott D Kathe, Ramiro Barrantes-Reynolds, Pawel Jaruga, Michael R Newton, Cynthia J Burrows, Viswanath Bandaru, Miral Dizdaroglu, Jeffrey P Bond, Susan S Wallace. Plant and fungal Fpg homologs are formamidopyrimidine DNA glycosylases but not 8-oxoguanine DNA glycosylases. DNA repair. 2009 May; 8(5):643-53. doi: 10.1016/j.dnarep.2008.12.013. [PMID: 19217358]
  • Andrew J Ridley, James R Whiteside, Trevor J McMillan, Sarah L Allinson. Cellular and sub-cellular responses to UVA in relation to carcinogenesis. International journal of radiation biology. 2009 Mar; 85(3):177-95. doi: 10.1080/09553000902740150. [PMID: 19296341]
  • J A Cross, C Brennan, T Gray, R C Temple, N Dozio, J C Hughes, N J Levell, H Murphy, D Fowler, D A Hughes, M J Sampson. Absence of telomere shortening and oxidative DNA damage in the young adult offspring of women with pre-gestational type 1 diabetes. Diabetologia. 2009 Feb; 52(2):226-34. doi: 10.1007/s00125-008-1207-5. [PMID: 19034420]
  • Yolanda Lorenzo, Amaia Azqueta, Luisa Luna, Félix Bonilla, Gemma Domínguez, Andrew R Collins. The carotenoid beta-cryptoxanthin stimulates the repair of DNA oxidation damage in addition to acting as an antioxidant in human cells. Carcinogenesis. 2009 Feb; 30(2):308-14. doi: 10.1093/carcin/bgn270. [PMID: 19056931]
  • Natalia I Dmitrieva, Hua Tang Chen, André Nussenzweig, Maurice B Burg. Knockout of Ku86 accelerates cellular senescence induced by high NaCl. Aging. 2009 Feb; 1(2):245-53. doi: 10.18632/aging.100022. [PMID: 19946467]
  • Zsolt Radak, Mustafa Atalay, Judit Jakus, István Boldogh, Kelvin Davies, Sataro Goto. Exercise improves import of 8-oxoguanine DNA glycosylase into the mitochondrial matrix of skeletal muscle and enhances the relative activity. Free radical biology & medicine. 2009 Jan; 46(2):238-43. doi: 10.1016/j.freeradbiomed.2008.10.022. [PMID: 18992806]
  • Yoji Kato, Natsuko Dozaki, Toshiyuki Nakamura, Noritoshi Kitamoto, Akihiro Yoshida, Michitaka Naito, Masayasu Kitamura, Toshihiko Osawa. Quantification of Modified Tyrosines in Healthy and Diabetic Human Urine using Liquid Chromatography/Tandem Mass Spectrometry. Journal of clinical biochemistry and nutrition. 2009 Jan; 44(1):67-78. doi: 10.3164/jcbn.08-185. [PMID: 19177191]
  • C-H Pan, C-C Chan, Y-L Huang, K-Y Wu. Urinary 1-hydroxypyrene and malondialdehyde in male workers in Chinese restaurants. Occupational and environmental medicine. 2008 Nov; 65(11):732-5. doi: 10.1136/oem.2007.036970. [PMID: 18940956]
  • Simona Simone, Yves Gorin, Chakradhar Velagapudi, Hanna E Abboud, Samy L Habib. Mechanism of oxidative DNA damage in diabetes: tuberin inactivation and downregulation of DNA repair enzyme 8-oxo-7,8-dihydro-2'-deoxyguanosine-DNA glycosylase. Diabetes. 2008 Oct; 57(10):2626-36. doi: 10.2337/db07-1579. [PMID: 18599524]
  • Eric van der Walt, Darren P Martin, Arvind Varsani, Jane E Polston, Edward P Rybicki. Experimental observations of rapid Maize streak virus evolution reveal a strand-specific nucleotide substitution bias. Virology journal. 2008 Sep; 5(?):104. doi: 10.1186/1743-422x-5-104. [PMID: 18816368]
  • Laureen C Colis, Paromita Raychaudhury, Ashis K Basu. Mutational specificity of gamma-radiation-induced guanine-thymine and thymine-guanine intrastrand cross-links in mammalian cells and translesion synthesis past the guanine-thymine lesion by human DNA polymerase eta. Biochemistry. 2008 Aug; 47(31):8070-9. doi: 10.1021/bi800529f. [PMID: 18616294]
  • Leslie A Bransfield, Alissa Rennie, Kala Visvanathan, Shelly-Ann Odwin, Thomas W Kensler, James D Yager, Marlin D Friesen, John D Groopman. Formation of two novel estrogen guanine adducts and HPLC/MS detection of 4-hydroxyestradiol-N7-guanine in human urine. Chemical research in toxicology. 2008 Aug; 21(8):1622-30. doi: 10.1021/tx800145w. [PMID: 18582124]
  • Yuko Tanimura, Kazuhiro Shimizu, Kai Tanabe, Takeshi Otsuki, Ryohei Yamauchi, Yuichi Matsubara, Motoyuki Iemitsu, Seiji Maeda, Ryuichi Ajisaka. Exercise-induced oxidative DNA damage and lymphocytopenia in sedentary young males. Medicine and science in sports and exercise. 2008 Aug; 40(8):1455-62. doi: 10.1249/mss.0b013e31817242cf. [PMID: 18614946]
  • Marcella Renis, Laura Calandra, Christian Scifo, Barbara Tomasello, Venera Cardile, Luca Vanella, Roberto Bei, Luca La Fauci, Fabio Galvano. Response of cell cycle/stress-related protein expression and DNA damage upon treatment of CaCo2 cells with anthocyanins. The British journal of nutrition. 2008 Jul; 100(1):27-35. doi: 10.1017/s0007114507876239. [PMID: 18053307]
  • Dongmei Li, Chuntao Yuan, Yi Gong, Yufeng Huang, Xiaodong Han. The effects of methyl tert-butyl ether (MTBE) on the male rat reproductive system. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2008 Jul; 46(7):2402-8. doi: 10.1016/j.fct.2008.03.024. [PMID: 18467015]
  • Neriman Gokden, Liwen Li, Haihong Zhang, Robert F Schafer, Steven Schichman, Margie A Scott, Bruce R Smoller, Chun-Yang Fan. Loss of heterozygosity of DNA repair gene, hOGG1, in renal cell carcinoma but not in renal papillary adenoma. Pathology international. 2008 Jun; 58(6):339-43. doi: 10.1111/j.1440-1827.2008.02234.x. [PMID: 18477212]
  • Tuula M Kalliomäki, Gordon McCallum, Sarah Jane Lunt, Peter G Wells, Richard P Hill. Analysis of the effects of exposure to acute hypoxia on oxidative lesions and tumour progression in a transgenic mouse breast cancer model. BMC cancer. 2008 May; 8(?):151. doi: 10.1186/1471-2407-8-151. [PMID: 18507854]
  • Daniel Gackowski, Rafal Rozalski, Agnieszka Siomek, Tomasz Dziaman, Krzysztof Nicpon, Maciej Klimarczyk, Aleksander Araszkiewicz, Ryszard Olinski. Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia. Journal of the neurological sciences. 2008 Mar; 266(1-2):57-62. doi: 10.1016/j.jns.2007.08.041. [PMID: 17888453]
  • Samy L Habib, Simona Simone, Jeff J Barnes, Hanna E Abboud. Tuberin haploinsufficiency is associated with the loss of OGG1 in rat kidney tumors. Molecular cancer. 2008 Jan; 7(?):10. doi: 10.1186/1476-4598-7-10. [PMID: 18218111]
  • Keisuke Tachibana, Daisuke Yamasaki, Kenji Ishimoto, Takefumi Doi. The Role of PPARs in Cancer. PPAR research. 2008; 2008(?):102737. doi: 10.1155/2008/102737. [PMID: 18584037]
  • Carrie V Breton, Molly L Kile, Paul J Catalano, Elaine Hoffman, Quazi Quamruzzaman, Mahmuder Rahman, Golam Mahiuddin, David C Christiani. GSTM1 and APE1 genotypes affect arsenic-induced oxidative stress: a repeated measures study. Environmental health : a global access science source. 2007 Dec; 6(?):39. doi: 10.1186/1476-069x-6-39. [PMID: 18053222]
  • Bhaskar Malayappan, Timothy J Garrett, Mark Segal, Christiaan Leeuwenburgh. Urinary analysis of 8-oxoguanine, 8-oxoguanosine, fapy-guanine and 8-oxo-2'-deoxyguanosine by high-performance liquid chromatography-electrospray tandem mass spectrometry as a measure of oxidative stress. Journal of chromatography. A. 2007 Oct; 1167(1):54-62. doi: 10.1016/j.chroma.2007.08.024. [PMID: 17765254]
  • Kyung Jin Lee, Hye Gwang Jeong. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage. Toxicology letters. 2007 Sep; 173(2):80-7. doi: 10.1016/j.toxlet.2007.06.008. [PMID: 17689207]
  • Ching-Hsein Chen, Tsan-Zon Liu, Chin-Hui Chen, Chung Hang Wong, Chi-Hung Chen, Fung-Jou Lu, Ssu Ching Chen. The efficacy of protective effects of tannic acid, gallic acid, ellagic acid, and propyl gallate against hydrogen peroxide-induced oxidative stress and DNA damages in IMR-90 cells. Molecular nutrition & food research. 2007 Aug; 51(8):962-8. doi: 10.1002/mnfr.200600230. [PMID: 17628875]
  • Barbara Tudek. Base excision repair modulation as a risk factor for human cancers. Molecular aspects of medicine. 2007 Jun; 28(3-4):258-75. doi: 10.1016/j.mam.2007.05.003. [PMID: 17628657]
  • Maria Teresa Russo, Gabriele De Luca, Paolo Degan, Margherita Bignami. Different DNA repair strategies to combat the threat from 8-oxoguanine. Mutation research. 2007 Jan; 614(1-2):69-76. doi: 10.1016/j.mrfmmm.2006.03.007. [PMID: 16769088]
  • Li Jiang, Yi Zhong, Shinya Akatsuka, Yu-Ting Liu, Khokon Kumar Dutta, Wen-Hua Lee, Janice Onuki, Ken-ichi Masumura, Takehiko Nohmi, Shinya Toyokuni. Deletion and single nucleotide substitution at G:C in the kidney of gpt delta transgenic mice after ferric nitrilotriacetate treatment. Cancer science. 2006 Nov; 97(11):1159-67. doi: 10.1111/j.1349-7006.2006.00301.x. [PMID: 16925583]
  • Ge Wang, Yang Hong, Michael K Johnson, Robert J Maier. Lipid peroxidation as a source of oxidative damage in Helicobacter pylori: protective roles of peroxiredoxins. Biochimica et biophysica acta. 2006 Nov; 1760(11):1596-603. doi: 10.1016/j.bbagen.2006.05.005. [PMID: 17069977]
  • P Therond. [Oxidative stress and damages to biomolecules (lipids, proteins, DNA)]. Annales pharmaceutiques francaises. 2006 Nov; 64(6):383-9. doi: 10.1016/s0003-4509(06)75333-0. [PMID: 17119467]
  • Eliette Touati, Valérie Michel, Jean-Michel Thiberge, Patrick Avé, Michel Huerre, Franck Bourgade, Arne Klungland, Agnès Labigne. Deficiency in OGG1 protects against inflammation and mutagenic effects associated with H. pylori infection in mouse. Helicobacter. 2006 Oct; 11(5):494-505. doi: 10.1111/j.1523-5378.2006.00442.x. [PMID: 16961812]
  • Zuzana Chovanová, Jana Muchová, Monika Sivonová, Monika Dvoráková, Ingrid Zitnanová, Iveta Waczulíková, Jana Trebatická, Igor Skodácek, Zdenka Duracková. Effect of polyphenolic extract, Pycnogenol, on the level of 8-oxoguanine in children suffering from attention deficit/hyperactivity disorder. Free radical research. 2006 Sep; 40(9):1003-10. doi: 10.1080/10715760600824902. [PMID: 17015282]
  • Eugenia A Kemeleva, Olga I Sinitsyna, Nataliya G Kolosova, Elena A Vasyunina, Dmitry O Zharkov, Kimberly A Conlon, Miguel Berrios, Georgy A Nevinsky. Immunofluorescent detection of 8-oxoguanine DNA lesions in liver cells from aging OXYS rats, a strain prone to overproduction of free radicals. Mutation research. 2006 Jul; 599(1-2):88-97. doi: 10.1016/j.mrfmmm.2006.01.008. [PMID: 16574166]
  • Jan Peter Thomas, Juergen Lautermann, Bernd Liedert, Frank Seiler, Juergen Thomale. High accumulation of platinum-DNA adducts in strial marginal cells of the cochlea is an early event in cisplatin but not carboplatin ototoxicity. Molecular pharmacology. 2006 Jul; 70(1):23-9. doi: 10.1124/mol.106.022244. [PMID: 16569706]
  • Steffen Loft, Peter Svoboda, Hiroshi Kasai, Anne Tjønneland, Ulla Vogel, Peter Møller, Kim Overvad, Ole Raaschou-Nielsen. Prospective study of 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion and the risk of lung cancer. Carcinogenesis. 2006 Jun; 27(6):1245-50. doi: 10.1093/carcin/bgi313. [PMID: 16364924]