aminopyrene (BioDeep_00000624650)

   


代谢物信息卡片


1-Pyrenylamine (acd/name 4.0)

化学式: C16H11N (217.0891446)
中文名称: 1-氨基芘
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC2=C3C(=C1)C=CC4=C(C=CC(=C43)C=C2)N
InChI: InChI=1S/C16H11N/c17-14-9-7-12-5-4-10-2-1-3-11-6-8-13(14)16(12)15(10)11/h1-9H,17H2

描述信息

同义名列表

9 个代谢物同义名

1-Pyrenylamine (acd/name 4.0); 1-Pyrenamine (acd/name 4.0); Pyren-1-ylamine; 3-Aminopyrene; 1-Aminopyrene; pyren-1-amine; 1-Pyrenamine; Amino-pyrene; aminopyrene



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Dinesh L Wadikar, M O Farooqui, Anirban Middey, Amit Bafana, Yogesh Pakade, Pravin Naoghare, A J Vanisree, Krishnamurthi Kannan, Saravanadevi Sivanesan. Assessment of occupational exposure to diesel particulate matter through evaluation of 1-nitropyrene and 1-aminopyrene in surface coal miners, India. Environmental monitoring and assessment. 2021 May; 193(6):342. doi: 10.1007/s10661-021-09121-y. [PMID: 34002328]
  • Hua Miao, Gang Cao, Xia-Qing Wu, Yuan-Yuan Chen, Dan-Qian Chen, Lin Chen, Nosratola D Vaziri, Ya-Long Feng, Wei Su, Yi Gao, Shougang Zhuang, Xiao-Yong Yu, Li Zhang, Yan Guo, Ying-Yong Zhao. Identification of endogenous 1-aminopyrene as a novel mediator of progressive chronic kidney disease via aryl hydrocarbon receptor activation. British journal of pharmacology. 2020 08; 177(15):3415-3435. doi: 10.1111/bph.15062. [PMID: 32219844]
  • Mengran Du, Benjamin J Mullins, Peter Franklin, A W Musk, Novak S J Elliot, Nita Sodhi-Berry, Edwin Junaldi, Nicholas de Klerk, Alison Reid. Measurement of urinary 1-aminopyrene and 1-hydroxypyrene as biomarkers of exposure to diesel particulate matter in gold miners. The Science of the total environment. 2019 Oct; 685(?):723-728. doi: 10.1016/j.scitotenv.2019.06.242. [PMID: 31234134]
  • N Podechard, X Tekpli, D Catheline, J A Holme, V Rioux, P Legrand, M Rialland, O Fardel, D Lagadic-Gossmann, V Lecureur. Mechanisms involved in lipid accumulation and apoptosis induced by 1-nitropyrene in Hepa1c1c7 cells. Toxicology letters. 2011 Oct; 206(3):289-99. doi: 10.1016/j.toxlet.2011.07.024. [PMID: 21872649]
  • Subramanian Suganya, Dominic Sophia, Chinthamony Arul Raj, Muthaiyan Ahalliya Rathi, Lakshmanan Thirumoorthi, Periyasamy Meenakshi, Dugganaboyana Guru Kumar, Velliyur Kanniyapan Gopalakrishnan. Amelioration of nitrobenzene-induced nephrotoxicity by the ethanol extract of the herb Euphorbia hirta. Pharmacognosy research. 2011 Jul; 3(3):201-7. doi: 10.4103/0974-8490.85009. [PMID: 22022170]
  • Robert J Laumbach, Howard M Kipen, Kathie Kelly-McNeil, Junfeng Zhang, Lin Zhang, Paul J Lioy, Pamela Ohman-Strickland, Jing Gong, Alexander Kusnecov, Nancy Fiedler. Sickness response symptoms among healthy volunteers after controlled exposures to diesel exhaust and psychological stress. Environmental health perspectives. 2011 Jul; 119(7):945-50. doi: 10.1289/ehp.1002631. [PMID: 21330231]
  • Susan Huyck, Pamela Ohman-Strickland, Lin Zhang, Jian Tong, X U Xu, Junfeng Jim Zhang. Determining times to maximum urine excretion of 1-aminopyrene after diesel exhaust exposure. Journal of exposure science & environmental epidemiology. 2010 Nov; 20(7):650-5. doi: 10.1038/jes.2010.29. [PMID: 20442755]
  • O Wongwattanasathien, K Kangsadalampai, L Tongyonk. Antimutagenicity of some flowers grown in Thailand. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2010 Apr; 48(4):1045-51. doi: 10.1016/j.fct.2010.01.018. [PMID: 20100534]
  • Robert Laumbach, Jian Tong, Lin Zhang, Pamela Ohman-Strickland, Alan Stern, Nancy Fiedler, Howard Kipen, Kathie Kelly-McNeil, Paul Lioy, Junfeng Zhang. Quantification of 1-aminopyrene in human urine after a controlled exposure to diesel exhaust. Journal of environmental monitoring : JEM. 2009 Jan; 11(1):153-9. doi: 10.1039/b810039j. [PMID: 19137151]
  • Masanaho Sasatsu, Hiraku Onishi, Yoshiharu Machida. Preparation and biodisposition of methoxypolyethylene glycol amine-poly(DL-lactic acid) copolymer nanoparticles loaded with pyrene-ended poly(DL-lactic acid). International journal of pharmaceutics. 2008 Jun; 358(1-2):271-7. doi: 10.1016/j.ijpharm.2008.03.011. [PMID: 18448290]
  • F Bryce, F Iverson, P Andrews, M Barker, W Cherry, R Mueller, O Pulido, S Hayward, S Fernie, D L Arnold. Effects elicited by toxaphene in the cynomolgus monkey (Macaca fascicularis): a pilot study. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2001 Dec; 39(12):1243-51. doi: 10.1016/s0278-6915(01)00068-0. [PMID: 11696398]
  • M Ferrer, A Sánchez-Lamar, J L Fuentes, J Barbé, M Llagostera. Studies on the antimutagenesis of Phyllanthus orbicularis: mechanisms involved against aromatic amines. Mutation research. 2001 Nov; 498(1-2):99-105. doi: 10.1016/s1383-5718(01)00270-4. [PMID: 11673075]
  • B Miksa, M Wilczynska, C Cierniewski, T Basinska, S Slomkowski. Composite poly(methyl methacrylate-methacrylic acid-2-hydroxyethyl methacrylate) latex for immunoassay. The case of plasminogen. Journal of biomaterials science. Polymer edition. 1995; 7(6):503-13. doi: 10.1163/156856295x00562. [PMID: 8608087]
  • B Miksa, S Slomkowski. Adsorption and covalent immobilization of human serum albumin (HSA) and gamma globulins (gamma G) onto poly(styrene/acrolein) latexes with pyrene, dansyl, and 2,4-dinitrophenyl labels. Journal of biomaterials science. Polymer edition. 1995; 7(1):77-96. doi: 10.1163/156856295x00841. [PMID: 7545003]
  • P T Scheepers, H J Thuis, M H Martens, R P Bos. Assessment of occupational exposure to diesel exhaust. The use of an immunoassay for the determination of urinary metabolites of nitroarenes and polycyclic aromatic hydrocarbons. Toxicology letters. 1994 Jun; 72(1-3):191-8. doi: 10.1016/0378-4274(94)90028-0. [PMID: 7515517]
  • L C King, M J Kohan, S E George, J Lewtas, L D Claxton. Metabolism of 1-nitropyrene by human, rat, and mouse intestinal flora: mutagenicity of isolated metabolites by direct analysis of HPLC fractions with a microsuspension reverse mutation assay. Journal of toxicology and environmental health. 1990 Nov; 31(3):179-92. doi: 10.1080/15287399009531447. [PMID: 2231777]
  • K Tatsumi, S Kitamura, H Amano, K Ueda. Comparative study on metabolic formation of N-arylformamides and N-arylacetamides from carcinogenic arylamines in mammalian species. Cancer research. 1989 Apr; 49(8):2059-64. doi: . [PMID: 2702648]
  • T H Zytkovicz. The 4-5S carcinogen binding protein binds 1-aminopyrene, 1-nitropyrene and (+)-benzo[a]pyrenediolepoxide and is found in 12 tissues of the DBA/2J mouse. Toxicology letters. 1987 Dec; 39(2-3):147-57. doi: 10.1016/0378-4274(87)90227-x. [PMID: 3120356]
  • R M Santella, L L Hsieh, F Perera. Immunologic quantification of carcinogen-DNA adducts. Basic life sciences. 1986; 38(?):509-17. doi: 10.1007/978-1-4615-9462-8_53. [PMID: 3090996]
  • K El-Bayoumy, C Sharma, Y M Louis, B Reddy, S S Hecht. The role of intestinal microflora in the metabolic reduction of 1-nitropyrene to 1-aminopyrene in conventional and germfree rats and in humans. Cancer letters. 1983 Jul; 19(3):311-6. doi: 10.1016/0304-3835(83)90100-3. [PMID: 6688375]
  • I Marinovic, J C Glasinovic, F Pimentel, M T Valdivia. [Evaluation of the C14-aminopyrine test in patients with chronic liver damage]. Revista medica de Chile. 1982 Jun; 110(6):555-9. doi: NULL. [PMID: 6819624]
  • G Marsili, R Tacconi, S Cipriani. Determination of serum iron and the total iron-binding capacity with a new chromogen, 4-aminophenazone. La Ricerca in clinica e in laboratorio. 1980 Apr; 10(2):423-9. doi: 10.1007/bf02905352. [PMID: 6893870]