FEMA 3773 (BioDeep_00000623402)
代谢物信息卡片
化学式: C10H11NaO4 (218.0555006)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES:
InChI:
描述信息
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Kerstin Schweiger, Verena Grüneis, Julia Treml, Claudia Galassi, Corinna M Karl, Jakob P Ley, Gerhard E Krammer, Barbara Lieder, Veronika Somoza. Sweet Taste Antagonist Lactisole Administered in Combination with Sucrose, But Not Glucose, Increases Energy Intake and Decreases Peripheral Serotonin in Male Subjects.
Nutrients.
2020 Oct; 12(10):. doi:
10.3390/nu12103133
. [PMID: 33066498] - Xiudao Song, Guoqiang Liang, Min Shi, Liang Zhou, Fei Wang, Lurong Zhang, Fei Huang, Guorong Jiang. Acute exposure to 3‑deoxyglucosone at high glucose levels impairs insulin secretion from β‑cells by downregulating the sweet taste receptor signaling pathway.
Molecular medicine reports.
2019 Jun; 19(6):5015-5022. doi:
10.3892/mmr.2019.10163
. [PMID: 31059088] - Fei Wang, Xiudao Song, Liang Zhou, Guoqiang Liang, Fei Huang, Guorong Jiang, Lurong Zhang. The downregulation of sweet taste receptor signaling in enteroendocrine L-cells mediates 3-deoxyglucosone-induced attenuation of high glucose-stimulated GLP-1 secretion.
Archives of physiology and biochemistry.
2018 Dec; 124(5):430-435. doi:
10.1080/13813455.2017.1419366
. [PMID: 29277113] - Melody Anne de Laat, Murad Hasan Kheder, Christopher Charles Pollitt, Martin Nicholas Sillence. Sweet taste receptor inhibitors: Potential treatment for equine insulin dysregulation.
PloS one.
2018; 13(6):e0200070. doi:
10.1371/journal.pone.0200070
. [PMID: 29958298] - Elnaz Karimian Azari, Kathleen R Smith, Fanchao Yi, Timothy F Osborne, Roberto Bizzotto, Andrea Mari, Richard E Pratley, George A Kyriazis. Inhibition of sweet chemosensory receptors alters insulin responses during glucose ingestion in healthy adults: a randomized crossover interventional study.
The American journal of clinical nutrition.
2017 04; 105(4):1001-1009. doi:
10.3945/ajcn.116.146001
. [PMID: 28251932] - Yoshiaki Ohtsu, Yuko Nakagawa, Masahiro Nagasawa, Shigeki Takeda, Hirokazu Arakawa, Itaru Kojima. Diverse signaling systems activated by the sweet taste receptor in human GLP-1-secreting cells.
Molecular and cellular endocrinology.
2014 Aug; 394(1-2):70-9. doi:
10.1016/j.mce.2014.07.004
. [PMID: 25017733] - Bo Liu, Matthew Ha, Xuan-Yu Meng, Mohammed Khaleduzzaman, Zhe Zhang, Xia Li, Meng Cui. Functional characterization of the heterodimeric sweet taste receptor T1R2 and T1R3 from a New World monkey species (squirrel monkey) and its response to sweet-tasting proteins.
Biochemical and biophysical research communications.
2012 Oct; 427(2):431-7. doi:
10.1016/j.bbrc.2012.09.083
. [PMID: 23000410] - Emeline L Maillet, Robert F Margolskee, Bedrich Mosinger. Phenoxy herbicides and fibrates potently inhibit the human chemosensory receptor subunit T1R3.
Journal of medicinal chemistry.
2009 Nov; 52(21):6931-5. doi:
10.1021/jm900823s
. [PMID: 19817384] - Nobuyuki Ide, Eriko Sato, Keisuke Ohta, Tetsuya Masuda, Naofumi Kitabatake. Interactions of the sweet-tasting proteins thaumatin and lysozyme with the human sweet-taste receptor.
Journal of agricultural and food chemistry.
2009 Jul; 57(13):5884-90. doi:
10.1021/jf803956f
. [PMID: 19489607] - Maude Le Gall, Vanessa Tobin, Emilie Stolarczyk, Véronique Dalet, Armelle Leturque, Edith Brot-Laroche. Sugar sensing by enterocytes combines polarity, membrane bound detectors and sugar metabolism.
Journal of cellular physiology.
2007 Dec; 213(3):834-43. doi:
10.1002/jcp.21245
. [PMID: 17786952] - Ken-ichiro Nakajima, Tomiko Asakura, Hideaki Oike, Yuji Morita, Akiko Shimizu-Ibuka, Takumi Misaka, Hiroyuki Sorimachi, Soichi Arai, Keiko Abe. Neoculin, a taste-modifying protein, is recognized by human sweet taste receptor.
Neuroreport.
2006 Aug; 17(12):1241-4. doi:
10.1097/01.wnr.0000230513.01339.3b
. [PMID: 16951562] - Christina Kuhn, Bernd Bufe, Marcel Winnig, Thomas Hofmann, Oliver Frank, Maik Behrens, Tatjana Lewtschenko, Jay P Slack, Cynthia D Ward, Wolfgang Meyerhof. Bitter taste receptors for saccharin and acesulfame K.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2004 Nov; 24(45):10260-5. doi:
10.1523/jneurosci.1225-04.2004
. [PMID: 15537898]