guttiferone A (BioDeep_00000622932)

   


代谢物信息卡片


3-[(3,4-dihydroxyphenyl)carbonyl]-4-hydroxy-8-methyl-1,5,7-tris(3-methylbut-2-en-1-yl)-8-(4-methylpent-3-en-1-yl)bicyclo[3.3.1]non-3-ene-2,9-dione

化学式: C38H50O6 (602.36072)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=CCCC1(C(CC2(C(=O)C(=C(C3=CC(=C(C=C3)O)O)O)C(=O)C1(C2=O)CC=C(C)C)CC=C(C)C)CC=C(C)C)C)C
InChI: InChI=1S/C38H50O6/c1-23(2)11-10-18-36(9)28(14-12-24(3)4)22-37(19-16-25(5)6)33(42)31(32(41)27-13-15-29(39)30(40)21-27)34(43)38(36,35(37)44)20-17-26(7)8/h11-13,15-17,21,28,39-41H,10,14,18-20,22H2,1-9H3/b32-31+/t28-,36+,37-,38+/m0/s1

描述信息

同义名列表

3 个代谢物同义名

guttiferone A; 3-[(3,4-dihydroxyphenyl)carbonyl]-4-hydroxy-8-methyl-1,5,7-tris(3-methylbut-2-en-1-yl)-8-(4-methylpent-3-en-1-yl)bicyclo[3.3.1]non-3-ene-2,9-dione; (+)-Guttiferone a



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Pauline Menelle, Jérôme Quintin, Kevin Cottet, Yann Fromentin, Joëlle Dupont, Marie-Christine Lallemand, Didier Buisson. Biotransformation of guttiferones, Symphonia globulifera metabolites, by Bipolaris cactivora, an endophytic fungus isolated from its leaves. Organic & biomolecular chemistry. 2021 02; 19(6):1378-1385. doi: 10.1039/d0ob02443k. [PMID: 33480950]
  • Romain Duval, Kevin Cottet, Magali Blaud, Anaïs Merckx, Sandrine Houzé, Philippe Grellier, Marie-Christine Lallemand, Sylvie Michel. A Photoalkylative Fluorogenic Probe of Guttiferone A for Live Cell Imaging and Proteome Labeling in Plasmodium falciparum. Molecules (Basel, Switzerland). 2020 Nov; 25(21):. doi: 10.3390/molecules25215139. [PMID: 33158263]
  • Hai-Ming Wu, Yu-Mei Li. In vitro antitumor activity of guttiferone-A in human breast cancer cells is mediated via apoptosis, mitochondrial mediated oxidative stress and reactive oxygen species production. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. 2017 Nov; 22(6):1500-1504. doi: ". [PMID: 29332344]
  • Kevin Cottet, Anne Neudörffer, Marina Kritsanida, Sylvie Michel, Marie-Christine Lallemand, Martine Largeron. Polycyclic Polyprenylated Xanthones from Symphonia globulifera: Isolation and Biomimetic Electrosynthesis. Journal of natural products. 2015 Aug; 78(8):2136-40. doi: 10.1021/acs.jnatprod.5b00239. [PMID: 26221771]
  • Kévin Cottet, Grégory Genta-Jouve, Yann Fromentin, Guillaume Odonne, Christophe Duplais, Olivier Laprévote, Sylvie Michel, Marie-Christine Lallemand. Comparative LC-MS-based metabolite profiling of the ancient tropical rainforest tree Symphonia globulifera. Phytochemistry. 2014 Dec; 108(?):102-8. doi: 10.1016/j.phytochem.2014.09.009. [PMID: 25301665]
  • Peterson Menezes Terrazas, Eduardo de Souza Marques, Luisa Nathália Bolda Mariano, Valdir Cechinel-Filho, Rivaldo Niero, Sergio Faloni Andrade, Edson Luis Maistro. Benzophenone guttiferone A from Garcinia achachairu Rusby (Clusiaceae) presents genotoxic effects in different cells of mice. PloS one. 2013; 8(11):e76485. doi: 10.1371/journal.pone.0076485. [PMID: 24250785]
  • Y Nuñez-Figueredo, L García-Pupo, J Ramírez-Sánchez, Y Alcántara-Isaac, O Cuesta-Rubio, R D Hernández, Z Naal, C Curti, G L Pardo-Andreu. Neuroprotective action and free radical scavenging activity of Guttiferone-A, a naturally occurring prenylated benzophenone. Arzneimittel-Forschung. 2012 Dec; 62(12):583-9. doi: 10.1055/s-0032-1327612. [PMID: 23115059]
  • Rivaldo Niero, Marlova Manhabosco Dal Molin, Suellen Silva, Natália Santos Damian, Láis Orlof Maia, Franco Delle Monache, Valdir Cechinel Filho, Sérgio Faloni de Andrade. Gastroprotective effects of extracts and guttiferone A isolated from Garcinia achachairu Rusby (Clusiaceae) against experimentally induced gastric lesions in mice. Naunyn-Schmiedeberg's archives of pharmacology. 2012 Nov; 385(11):1103-9. doi: 10.1007/s00210-012-0788-1. [PMID: 22926730]
  • Marlova Manhabosco Dal Molin, Suellen Silva, Douglas Rafael Alves, Nara Lins Meira Quintão, Franco Delle Monache, Valdir Cechinel Filho, Rivaldo Niero. Phytochemical analysis and antinociceptive properties of the seeds of Garcinia achachairu. Archives of pharmacal research. 2012 Mar; 35(4):623-31. doi: 10.1007/s12272-012-0405-3. [PMID: 22553054]
  • Yanier Núñez Figueredo, Laura García-Pupo, Osmany Cuesta Rubio, René Delgado Hernández, Zeki Naal, Carlos Curti, Gilberto L Pardo Andreu. A strong protective action of guttiferone-A, a naturally occurring prenylated benzophenone, against iron-induced neuronal cell damage. Journal of pharmacological sciences. 2011; 116(1):36-46. doi: 10.1254/jphs.10273fp. [PMID: 21512303]