6-(methylsulfinyl)hexyl isothiocyanate (BioDeep_00000621933)

   


代谢物信息卡片


1-isothiocyanato-6-(Methylsulfinyl)hexane, 9ci

化学式: C8H15NOS2 (205.0595)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CS(=O)CCCCCCN=C=S
InChI: InChI=1S/C8H15NOS2/c1-12(10)7-5-3-2-4-6-9-8-11/h2-7H2,1H3

描述信息

同义名列表

4 个代谢物同义名

1-isothiocyanato-6-(Methylsulfinyl)hexane, 9ci; 1-Isothiocyanato-6-(methylsulfinyl)hexane; 1-isothiocyanato-6-methanesulfinylhexane; 6-(methylsulfinyl)hexyl isothiocyanate



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Jui-Feng Lin, Chih-Wen Chi, Yu-Chuen Huang, Tung-Hu Tsai, Yu-Jen Chen. Anti-Cancer Effects of Oxygen-Atom-Modified Derivatives of Wasabi Components on Human Leukemia Cells. International journal of molecular sciences. 2023 Apr; 24(7):. doi: 10.3390/ijms24076823. [PMID: 37047794]
  • Kun-Ming Wu, Hui-Fen Liao, Chih-Wen Chi, Yu Ru Kou, Yu-Jen Chen. Wasabi Compound 6-(Methylsulfinyl) Hexyl Isothiocyanate Induces Cell Death with Coexisting Mitotic Arrest and Autophagy in Human Chronic Myelogenous Leukemia K562 Cells. Biomolecules. 2019 11; 9(12):. doi: 10.3390/biom9120774. [PMID: 31771225]
  • Min-Ju Lee, Wen-Ser Tseng, Jerry Cheng-Yen Lai, Hui-Ru Shieh, Chih-Wen Chi, Yu-Jen Chen. Differential Pharmacological Activities of Oxygen Numbers on the Sulfoxide Moiety of Wasabi Compound 6-(Methylsulfinyl) Hexyl Isothiocyanate in Human Oral Cancer Cells. Molecules (Basel, Switzerland). 2018 Sep; 23(10):. doi: 10.3390/molecules23102427. [PMID: 30248933]
  • Yoko Fuke, Madoka Hishinuma, Mayumi Namikawa, Yoshie Oishi, Takeshi Matsuzaki. Wasabi-derived 6-(methylsulfinyl)hexyl isothiocyanate induces apoptosis in human breast cancer by possible involvement of the NF-κB pathways. Nutrition and cancer. 2014; 66(5):879-87. doi: 10.1080/01635581.2014.916322. [PMID: 24895898]
  • Hideaki Yamaguchi, Yumi Kidachi, Katsuyoshi Kamiie, Toshiro Noshita, Hironori Umetsu, Yoko Fuke, Kazuo Ryoyama. Utilization of 6-(methylsulfinyl)hexyl isothiocyanate for sensitization of tumor cells to antitumor agents in combination therapies. Biochemical pharmacology. 2013 Aug; 86(4):458-68. doi: 10.1016/j.bcp.2013.06.008. [PMID: 23791871]
  • Kunitoshi Uchida, Yosuke Miura, Masashi Nagai, Makoto Tominaga. Isothiocyanates from Wasabia japonica activate transient receptor potential ankyrin 1 channel. Chemical senses. 2012 Nov; 37(9):809-18. doi: 10.1093/chemse/bjs065. [PMID: 22869685]
  • De-Xing Hou, Yoshimi Korenori, Shunsuke Tanigawa, Tomoe Yamada-Kato, Masashi Nagai, Xi He, Jianhua He. Dynamics of Nrf2 and Keap1 in ARE-mediated NQO1 expression by wasabi 6-(methylsulfinyl)hexyl isothiocyanate. Journal of agricultural and food chemistry. 2011 Nov; 59(22):11975-82. doi: 10.1021/jf2032439. [PMID: 22010800]
  • Young Sun Lee, Jae Ha Yang, Man Jong Bae, Wang Keun Yoo, Shen Ye, Charlie C L Xue, Chun Guang Li. Anti-oxidant and Anti-hypercholesterolemic Activities of Wasabia japonica. Evidence-based complementary and alternative medicine : eCAM. 2010 Dec; 7(4):459-64. doi: 10.1093/ecam/nen038. [PMID: 18955343]
  • Toshiyuki Nakamura, Noritoshi Kitamoto, Toshihiko Osawa, Yoji Kato. Immunochemical detection of food-derived isothiocyanate as a lysine conjugate. Bioscience, biotechnology, and biochemistry. 2010; 74(3):536-40. doi: 10.1271/bbb.90728. [PMID: 20208364]
  • Toshiro Noshita, Yumi Kidachi, Hirokazu Funayama, Hiromasa Kiyota, Hideaki Yamaguchi, Kazuo Ryoyama. Anti-nitric oxide production activity of isothiocyanates correlates with their polar surface area rather than their lipophilicity. European journal of medicinal chemistry. 2009 Dec; 44(12):4931-6. doi: 10.1016/j.ejmech.2009.08.005. [PMID: 19716210]
  • Yoko Fuke, Shoko Shinoda, Ikuko Nagata, Saeko Sawaki, Mituyoshi Murata, Kazuo Ryoyama, Keiichi Koizumi, Ikuo Saiki, Takahiro Nomura. Preventive effect of oral administration of 6-(methylsulfinyl)hexyl isothiocyanate derived from wasabi (Wasabia japonica Matsum) against pulmonary metastasis of B16-BL6 mouse melanoma cells. Cancer detection and prevention. 2006; 30(2):174-9. doi: 10.1016/j.cdp.2005.10.005. [PMID: 16647224]
  • Tomohiro Nabekura, Shizu Kamiyama, Shuji Kitagawa. Effects of dietary chemopreventive phytochemicals on P-glycoprotein function. Biochemical and biophysical research communications. 2005 Feb; 327(3):866-70. doi: 10.1016/j.bbrc.2004.12.081. [PMID: 15649425]
  • Yasujiro Morimitsu, Yoko Nakagawa, Kazuhiro Hayashi, Hiroyuki Fujii, Takeshi Kumagai, Yoshimasa Nakamura, Toshihiko Osawa, Fumihiko Horio, Ken Itoh, Katsuyuki Iida, Masayuki Yamamoto, Koji Uchida. A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway. The Journal of biological chemistry. 2002 Feb; 277(5):3456-63. doi: 10.1074/jbc.m110244200. [PMID: 11706044]