Alkest TW 20 (BioDeep_00000621031)
代谢物信息卡片
2-{2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy}ethyl dodecanoate
化学式: C26H50O10 (522.34038)
中文名称: 吐温20(TWEEN ® 20)
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCC(=O)OCCOCC(C1C(C(CO1)OCCO)OCCO)OCCO
InChI: InChI=1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3
描述信息
D010592 - Pharmaceutic Aids > D014677 - Pharmaceutical Vehicles > D005079 - Excipients
D013501 - Surface-Active Agents > D011092 - Polyethylene Glycols
D013501 - Surface-Active Agents > D011136 - Polysorbates
D001697 - Biomedical and Dental Materials
同义名列表
数据库引用编号
6 个数据库交叉引用编号
- PubChem: 443314
- Metlin: METLIN92150
- ChEMBL: CHEMBL371631
- MeSH: Polysorbates
- CAS: 1052273-76-3
- CAS: 9005-64-5
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Khoa A Nguyen, Vincent J P Boerkamp, John P M van Duynhoven, Arend Dubbelboer, Marie Hennebelle, Peter A Wierenga. A mechanistic kinetic model for lipid oxidation in Tween 20-stabilized O/W emulsions.
Food chemistry.
2024 Sep; 451(?):139404. doi:
10.1016/j.foodchem.2024.139404. [PMID: 38714112] - Eunji Jeon, Moonhee Park, Abhik Mojumdar, Young Hwan Kim, Jong-Soon Choi, Kun Cho. Optimized quantification of fatty acids in complex media using advanced analytical techniques.
Rapid communications in mass spectrometry : RCM.
2024 Jul; 38(14):e9764. doi:
10.1002/rcm.9764. [PMID: 38714901] - Jue Wang, Huimin Sun, Huiying Yang, Rui Yang, Xiaoyu Zhu, Shengya Guo, Yanfeng Huang, Yiqiao Xu, Chunqi Li, Jiasheng Tu, Chunmeng Sun. Dessecting the toxicological profile of polysorbate 80 (PS80): comparative analysis of constituent variability and biological impact using a zebrafish model.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2024 Jul; 198(?):106796. doi:
10.1016/j.ejps.2024.106796. [PMID: 38735400] - Renata Vardanega, Fernanda L Lüdtke, Luís Loureiro, Raquel F S Gonçalves, Ana C Pinheiro, António A Vicente. Development and characterization of nanostructured lipid carriers for cannabidiol delivery.
Food chemistry.
2024 May; 441(?):138295. doi:
10.1016/j.foodchem.2023.138295. [PMID: 38183719] - Jiin Felgner, Elizabeth Clarke, Jenny E Hernandez-Davies, Sharon Jan, Ariel S Wirchnianski, Aarti Jain, Rie Nakajima, Algimantas Jasinskas, Erwin Strahsburger, Kartik Chandran, Steven Bradfute, D Huw Davies. Broad antibody and T cell responses to Ebola, Sudan, and Bundibugyo ebolaviruses using mono- and multi-valent adjuvanted glycoprotein vaccines.
Antiviral research.
2024 May; 225(?):105851. doi:
10.1016/j.antiviral.2024.105851. [PMID: 38458540] - Enjun Xie, Yunmei Chen, Wanbao Yang, Quan Pan, James Zheng Shen, Fenghua Zhou, Jie Shen, Tao Li, Qili Li, Xiaopeng Li. Long-term exposure to dietary emulsifier Tween 80 promotes liver lipid accumulation and induces different-grade inflammation in young and aged mice.
Food research international (Ottawa, Ont.).
2024 May; 184(?):114205. doi:
10.1016/j.foodres.2024.114205. [PMID: 38609253] - Lilit Grigoryan, Yupeng Feng, Lorenza Bellusci, Lilin Lai, Bushra Wali, Madison Ellis, Meng Yuan, Prabhu S Arunachalam, Mengyun Hu, Sangeeta Kowli, Sheena Gupta, Sofia Maysel-Auslender, Holden T Maecker, Hady Samaha, Nadine Rouphael, Ian A Wilson, Alberto C Moreno, Mehul S Suthar, Surender Khurana, Stéphane Pillet, Nathalie Charland, Brian J Ward, Bali Pulendran. AS03 adjuvant enhances the magnitude, persistence, and clonal breadth of memory B cell responses to a plant-based COVID-19 vaccine in humans.
Science immunology.
2024 Apr; 9(94):eadi8039. doi:
10.1126/sciimmunol.adi8039. [PMID: 38579013] - Sarita Maurya, Manish Gaur, Mohd Sohail Akhtar, Awadh Bihari Yadav. Evaluation of Drug-Loaded and Surface-Adsorbed DNase/Tween-80 Solid Lipid Nanoparticles against Staphylococcus aureus Biofilms.
ACS applied bio materials.
2024 Mar; 7(3):1501-1512. doi:
10.1021/acsabm.3c00887. [PMID: 38418375] - Guangyan Zheng, Wenli Wu, Zemei Liu, Yuanju Lv, Yongming Luo, Xin Che, Lihong Wang. Quercetin nanocrystals prepared using a microfluidic chip with improved in vitro dissolution.
Pharmaceutical development and technology.
2024 Mar; 29(3):143-152. doi:
10.1080/10837450.2024.2315444. [PMID: 38353125] - Daniel Palberg, Emma Kaszecki, Chetan Dhanjal, Anna Kisiała, Erin N Morrison, Naomi Stock, R J Neil Emery. Impact of glyphosate and glyphosate-based herbicides on phyllospheric Methylobacterium.
BMC plant biology.
2024 Feb; 24(1):119. doi:
10.1186/s12870-024-04818-x. [PMID: 38369476] - Rozh Q Ameen, Zahra A Amin, Hiwa O Ahmad, Diler D Ghafur, Melodya G Toma, Nyan Sabah, Muhammad Fakhir, Gardoon Abdulla. Gastroprotective effect of rhodanine and 2,4-thiazolidinediones scaffolds in rat stomachs by contribution of anti-apoptotic (BCL-2) and tumor suppressor (P53) proteins.
Scientific reports.
2024 01; 14(1):1699. doi:
10.1038/s41598-024-51446-4. [PMID: 38242960] - Piyong Sola, Kusuma Kumari Garikapati, Praveen Thaggikuppe Krishnamurthy, Mamta Kumari. Polysorbate 80 surface modified SLNs of formoterol suppress SNCA gene and mitochondrial oxidative stress in mice model of Parkinson's disease.
Scientific reports.
2023 11; 13(1):19942. doi:
10.1038/s41598-023-46511-3. [PMID: 37968340] - Wenwen Lv, Jingyi Song, Rifat Nowshin Raka, Jinlong Sun, Guizhi Shi, Hua Wu, Junsong Xiao, Duoxia Xu. Effects of food emulsifiers on high fat-diet-induced obesity, intestinal inflammation, changes in bile acid profile, and liver dysfunction.
Food research international (Ottawa, Ont.).
2023 11; 173(Pt 1):113302. doi:
10.1016/j.foodres.2023.113302. [PMID: 37803614] - Yao-Kun Xiong, Rui Li, Na Wan, Wen-Jun Gao, Xiao-Ya Wang, Min Xie, Qin Zhang, Si Yang, Hua Zhang. [Preparation and quality evaluation of total flavonoids microemulsion of 'Pueraria lobata-Hovenia dulcis'].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2023 Oct; 48(20):5540-5547. doi:
10.19540/j.cnki.cjcmm.20230614.301. [PMID: 38114146] - Toon Ieven, Lieve Coorevits, Martijn Vandebotermet, Sebastiaan Tuyls, Hélène Vanneste, Lisa Santy, Dries Wets, Paul Proost, Glynis Frans, David Devolder, Christine Breynaert, Dominique M A Bullens, Rik Schrijvers. Endotyping of IgE-Mediated Polyethylene Glycol and/or Polysorbate 80 Allergy.
The journal of allergy and clinical immunology. In practice.
2023 10; 11(10):3146-3160. doi:
10.1016/j.jaip.2023.06.031. [PMID: 37380070] - Nan Zhang, Yi Yang, Jiacheng Wu, Chunyi Xu, Yi Ma, Yinqing Zhang, Lingyan Zhu. Efficient remediation of soils contaminated with petroleum hydrocarbons using sustainable plant-derived surfactants.
Environmental pollution (Barking, Essex : 1987).
2023 Sep; ?(?):122566. doi:
10.1016/j.envpol.2023.122566. [PMID: 37717897] - Xiaoqiang Chen, Caixia Liu, Yuxue Zhang, Ruixiang Shao, Jun He, Wei Huang, Zhong Liu. Regulating effects of phytosterol esters-loaded emulsions stabilized with green tea polysaccharide conjugates and Tween on lipids in KKAy mice.
International journal of biological macromolecules.
2023 Jul; 243(?):125235. doi:
10.1016/j.ijbiomac.2023.125235. [PMID: 37290551] - Ahmet Doğan Ergin, Çağatay Oltulu, Büşra Koç. Enhanced Cytotoxic Activity of 6-Mercaptopurine-Loaded Solid Lipid Nanoparticles in Hepatic Cancer Treatment.
Assay and drug development technologies.
2023 Jul; ?(?):. doi:
10.1089/adt.2023.007. [PMID: 37417972] - Amanda C Caritá, Jacqueline Resende de Azevedo, Yves Chevalier, Delphine Arquier, Marcus V Buri, Karin A Riske, Gislaine Ricci Leonardi, Marie-Alexandrine Bolzinger. Elastic cationic liposomes for vitamin C delivery: Development, characterization and skin absorption study.
International journal of pharmaceutics.
2023 May; 638(?):122897. doi:
10.1016/j.ijpharm.2023.122897. [PMID: 37003313] - Ruiling Li, Na Wu, Hui Xue, Binghong Gao, Huilan Liu, Tianfeng Han, Xiaobo Hu, Yonggang Tu, Yan Zhao. Influence and effect mechanism of filler type on the physicochemical properties, microbial numbers, and digestibility of ovalbumin emulsion gels during storage.
Food & function.
2023 Apr; 14(8):3779-3792. doi:
10.1039/d2fo03526j. [PMID: 36995104] - Malihe Karimi, Hossein Kamali, Shaghayegh Fakhrmohammadi, Elaheh Khezri, Bizhan Malaekeh-Nikouei, Marzieh Mohammadi. Prolonged local delivery of doxorubicin to cancer cells using lipid liquid crystalline system.
International journal of pharmaceutics.
2023 Apr; 639(?):122947. doi:
10.1016/j.ijpharm.2023.122947. [PMID: 37044227] - Periakaruppan Nithya, Sathya Raghunathan, Muthusamy Prabakaran, Susaimanickam Arul Antony, Davoodbasha MubarakAli. Synthesis and Characterization of Tween-20 Capped Biosynthesized Silver Nanoparticles for Anticancer and Antimicrobial Property.
Applied biochemistry and biotechnology.
2023 Apr; 195(4):2282-2293. doi:
10.1007/s12010-022-04069-2. [PMID: 35802241] - Espoir K Kambale, Frederick M Katemo, Joëlle Quetin-Leclercq, Patrick B Memvanga, Ana Beloqui. 'Green'-synthesized zinc oxide nanoparticles and plant extracts: A comparison between synthesis processes and antihyperglycemic activity.
International journal of pharmaceutics.
2023 Mar; 635(?):122715. doi:
10.1016/j.ijpharm.2023.122715. [PMID: 36773728] - Kunpeng Yu, Cheng Peng, Yanling Lin, Lijun Li, Hui Ni, Qingbiao Li. [Expression of β-glucosidase An-bgl3 from Aspergillus niger for conversion of scopolin].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology.
2023 Mar; 39(3):1232-1246. doi:
10.13345/j.cjb.220709. [PMID: 36994584] - Segun A Aderibigbe, Sunday O Idowu, Ajibola A Olaniyi. Isotonic, aqueous-based media as simple and suitable test media for short-term Haemonchus placei adult worm motility assay.
Experimental parasitology.
2023 Mar; 249(?):108516. doi:
10.1016/j.exppara.2023.108516. [PMID: 36967034] - Veerawat Teeranachaideekul, Siriwat Soontaranon, Supreeya Sukhasem, Doungdaw Chantasart, Amaraporn Wongrakpanich. Influence of the emulsifier on nanostructure and clinical application of liquid crystalline emulsions.
Scientific reports.
2023 03; 13(1):4185. doi:
10.1038/s41598-023-31329-w. [PMID: 36918671] - Dan-Ni Lu, Qian Xie, Zhuo Xu, Jian-Mei Yuan, Rong Ma, Jian Wang. [Protective effects of three kinds of borneol on different brain regions in acute cerebral ischemia/reperfusion model rats].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2023 Mar; 48(5):1289-1299. doi:
10.19540/j.cnki.cjcmm.20221025.406. [PMID: 37005813] - Rui Li, Baskaran Stephen Inbaraj, Bing-Huei Chen. Quantification of Xanthone and Anthocyanin in Mangosteen Peel by UPLC-MS/MS and Preparation of Nanoemulsions for Studying Their Inhibition Effects on Liver Cancer Cells.
International journal of molecular sciences.
2023 Feb; 24(4):. doi:
10.3390/ijms24043934. [PMID: 36835343] - M A Sundaramahalingam, C Amrutha, J Rajeshbanu, K Thirukumaran, S Manibalan, Muthupandian Ashokkumar, P Sivashanmugam. In silico approach for enhancing innate lipid content of Yarrowia lipolytica, by blocking the acyl-CoA oxidase-1 enzyme, using various analogous compounds of lipids.
Journal of biomolecular structure & dynamics.
2023 02; 41(2):511-524. doi:
10.1080/07391102.2021.2008498. [PMID: 34825634] - Thiloka Kariyawasam, Paul D Prenzler, Julia A Howitt, Gregory S Doran. Eucalyptus saponin- and sophorolipid-mediated desorption of polycyclic aromatic hydrocarbons from contaminated soil and sediment.
Environmental science and pollution research international.
2023 Feb; 30(8):21638-21653. doi:
10.1007/s11356-022-23562-z. [PMID: 36271995] - Haiyang Jiang, Shaobin Zhong, Paul Schwarz, Bingcan Chen, Jiajia Rao. Antifungal activity, mycotoxin inhibitory efficacy, and mode of action of hop essential oil nanoemulsion against Fusarium graminearum.
Food chemistry.
2023 Jan; 400(?):134016. doi:
10.1016/j.foodchem.2022.134016. [PMID: 36084588] - Rui Zhao, Meng Yu, Zhe Sun, Lin-Jie Li, Xin-Yu Guo, Yong Xu, Xue-Min Wu. Regulating droplet impact and wetting behaviors on hydrophobic leaves using a nonionic surfactant.
Journal of colloid and interface science.
2023 Jan; 629(Pt A):926-937. doi:
10.1016/j.jcis.2022.08.179. [PMID: 36152617] - Javed Khan, Muhammad Ishtiaq Ali, Asif Jamal, Mushtaq Ahmad, Jahangir Khan Achakzai, Muhammad Zafar. Response of mixed bacterial culture towards dibenzothiophene desulfurization under the influence of surfactants and microscopically (SEM and TEM) characterized magnetic Fe3 O4 nanoparticles.
Microscopy research and technique.
2022 Dec; 85(12):3838-3849. doi:
10.1002/jemt.24230. [PMID: 36111961] - Julieta N Naso, Fernando A Bellesi, Víctor M Pizones Ruiz-Henestrosa, Ana M R Pilosof. Solubilization of lipolysis products in mixed micelles is enhanced in presence of bile salts and Tween 80 as revealed by a model study (oleic acid) and emulsified chia-oil.
Food research international (Ottawa, Ont.).
2022 11; 161(?):111804. doi:
10.1016/j.foodres.2022.111804. [PMID: 36192949] - Adarsha Gupta, Max J H Worthington, Justin M Chalker, Munish Puri. Integration of the Exogenous Tuning of Thraustochytrid Fermentation and Sulfur Polymerization of Single-Cell Oil for Developing Plant-like Oils.
Marine drugs.
2022 Oct; 20(10):. doi:
10.3390/md20100655. [PMID: 36286478] - Ann-Christin Jacobsen, Aleksei Kabedev, Patrick D Sinko, Johan E Palm, Christel A S Bergström, Alexandra Teleki. Intrinsic lipolysis rate for systematic design of lipid-based formulations.
Drug delivery and translational research.
2022 Oct; ?(?):. doi:
10.1007/s13346-022-01246-y. [PMID: 36209313] - Mohamad Rahmati, Ebrahim Babapoor, Mehrouz Dezfulian. Amikacin-loaded niosome nanoparticles improve amikacin activity against antibiotic-resistant Klebsiella pneumoniae strains.
World journal of microbiology & biotechnology.
2022 Oct; 38(12):230. doi:
10.1007/s11274-022-03405-2. [PMID: 36184645] - Karin Schroën, Claire C Berton-Carabin. A unifying approach to lipid oxidation in emulsions: Modelling and experimental validation.
Food research international (Ottawa, Ont.).
2022 10; 160(?):111621. doi:
10.1016/j.foodres.2022.111621. [PMID: 36076435] - Ellen Denise Prado Almeida, Luiz André Santos Silva, Guilherme Rodolfo Souza de Araujo, Monalisa Martins Montalvão, Saulo Santos Matos, Joyce Kelly Marinheiro da Cunha Gonsalves, Rogéria de Souza Nunes, Cristiano Teles de Meneses, Rennan Geovanny Oliveira Araujo, Víctor Hugo Vitorino Sarmento, Waldecy De Lucca, Cristiane Bani Correa, José Joatan Rodrigues, Ana Amélia Moreira Lira. Chitosan-functionalized nanostructured lipid carriers containing chloroaluminum phthalocyanine for photodynamic therapy of skin cancer.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2022 Oct; 179(?):221-231. doi:
10.1016/j.ejpb.2022.09.009. [PMID: 36122783] - Fernanda Luisa Lüdtke, Marcella Aparecida Stahl, Renato Grimaldi, Marcus Bruno Soares Forte, Mirna Lúcia Gigante, Ana Paula Badan Ribeiro. Optimization of high pressure homogenization conditions to produce nanostructured lipid carriers using natural and synthetic emulsifiers.
Food research international (Ottawa, Ont.).
2022 10; 160(?):111746. doi:
10.1016/j.foodres.2022.111746. [PMID: 36076468] - Kesavan Subaharan, Periyasamy Senthamarai Selvan, Thagare Manjunatha Subramanya, Rajendran Senthoorraja, Sowmya Manjunath, Tania Das, Vppalayam Shanmugam Pragadheesh, Nandagopal Bakthavatsalam, Muthu Gounder Mohan, Sengottayan Senthil-Nathan, Sreehari Uragayala, Paulraj Philip Samuel, Renu Govindarajan, Muthuswamy Eswaramoorthy. Ultrasound-assisted nanoemulsion of Trachyspermum ammi essential oil and its constituent thymol on toxicity and biochemical aspect of Aedes aegypti.
Environmental science and pollution research international.
2022 Oct; 29(47):71326-71337. doi:
10.1007/s11356-022-20870-2. [PMID: 35595904] - Wenzhu Li, Fang Zhao, Xinyuan Xie, Jiayu Yang, Jianyang Pan, Haibin Qu. Quantitative profiling of comprehensive composition in compound herbal injections: An NMR approach applied on Shenmai injection.
Phytochemical analysis : PCA.
2022 Oct; 33(7):1045-1057. doi:
10.1002/pca.3158. [PMID: 35750658] - Bakr Ahmed, Md Rizwanullah, Showkat Rasool Mir, M Shaheer Akhtar, Saima Amin. Development of cannabidiol nanoemulsion for direct nose to brain delivery: statistical optimization,in vitroandin vivoevaluation.
Biomedical materials (Bristol, England).
2022 Sep; 17(6):. doi:
10.1088/1748-605x/ac9267. [PMID: 36108625] - Vaikunthavasan Thiruchenthooran, Marta Świtalska, Lorena Bonilla, Marta Espina, Maria Luisa García, Joanna Wietrzyk, Elena Sánchez-López, Anna Gliszczyńska. Novel Strategies against Cancer: Dexibuprofen-Loaded Nanostructured Lipid Carriers.
International journal of molecular sciences.
2022 Sep; 23(19):. doi:
10.3390/ijms231911310. [PMID: 36232614] - Zhengjun Chen, Xinyan Hao, Hairui Wang, Xiaofang Zhong, Xiaoyan Chen, Yuanhao Zhao, Yuandong Zhang, Guangsheng Du, Xun Sun. Smart combination of aluminum hydroxide and MF59 to induce strong cellular immune responses.
Journal of controlled release : official journal of the Controlled Release Society.
2022 09; 349(?):699-711. doi:
10.1016/j.jconrel.2022.07.032. [PMID: 35907590] - Fei Wang, Jiuyan Chen, Yalei Xu, Usman Farooq, Taotao Lu, Weifeng Chen, Xinhai Wang, Zhichong Qi. Surfactants-mediated the enhanced mobility of tetracycline in saturated porous media and its variation with aqueous chemistry.
Chemosphere.
2022 Sep; 302(?):134887. doi:
10.1016/j.chemosphere.2022.134887. [PMID: 35551941] - Hyemin Park, Dongpil Lee, Jae-Eung Kim, Seonmi Park, Joo Hyun Park, Cheol Woong Ha, Minji Baek, Seok-Hwan Yoon, Kwang Hyun Park, Peter Lee, Ji-Sook Hahn. Efficient production of retinol in Yarrowia lipolytica by increasing stability using antioxidant and detergent extraction.
Metabolic engineering.
2022 09; 73(?):26-37. doi:
10.1016/j.ymben.2022.06.001. [PMID: 35671979] - Björn-Hendrik Peters, Yangjie Wei, C Russell Middaugh, Christian Schöneich. Intra-Micellar and Extra-Micellar Oxidation in Phosphate and Histidine Buffers Containing Polysorbate 80.
Journal of pharmaceutical sciences.
2022 09; 111(9):2435-2444. doi:
10.1016/j.xphs.2022.06.011. [PMID: 35716732] - Marta Tramontana, Leonardo Bianchi, Filippo Biondi, Katharina Hansel, Nicolò Malatesta, Rossella Marietti, Luca Stingeni. A case of delayed allergy to polyethylene glycol 2000 and polysorbate 80 confirmed by patch test: Consequences for anti-SARS-CoV2 vaccination?.
Contact dermatitis.
2022 Aug; 87(2):209-210. doi:
10.1111/cod.14131. [PMID: 35445750] - Mubashar Rehman, Muhammad Ziaullah Khan, Muhammad Tayyab, Asadullah Madni, Qandeel Khalid. Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs.
Journal of visualized experiments : JoVE.
2022 07; ?(185):. doi:
10.3791/63995. [PMID: 35969097] - Yue Li, Jinlian Duan, Heng Xia, Yongkun Li, Bin Shu, Weigang Duan. Macromolecules in polysorbate 80 for injection: an important cause of anaphylactoid reactions.
BMC pharmacology & toxicology.
2022 07; 23(1):52. doi:
10.1186/s40360-022-00591-5. [PMID: 35850712] - M Borduas, P A Spagnuolo, A G Marangoni, M G Corradini, A J Wright, M A Rogers. Lipid crystallinity of oil-in-water emulsions alters in vitro.
Food chemistry.
2022 Jul; 382(?):132326. doi:
10.1016/j.foodchem.2022.132326. [PMID: 35152026] - Milad Ebadi, Claire McCague, Ophelia Vallee, Patrick K Taylor, Amy H Y Lee, Majid Bahrami. Salt and surfactant coated filters with antiviral properties and low pressure drop for prospective SARS-CoV2 applications.
Scientific reports.
2022 Jul; 12(1):11546. doi:
10.1038/s41598-022-15203-9. [PMID: 35798756] - Kristen M Ahlschwede, Edward Ofori, Terrick Andey, Anita Osei, John S Somberg. Formulation, Characterization, and the Diuretic Effects of a New Intravenous Metolazone Emulsion.
Drug research.
2022 Jul; 72(6):299-305. doi:
10.1055/a-1813-9489. [PMID: 35537450] - Iris M Otani, Lulu R Tsao, Monica Tang. Coronavirus disease 2019 vaccine administration in patients with reported reactions to polyethylene glycol- and polysorbate-containing therapeutics.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
2022 07; 129(1):88-94.e1. doi:
10.1016/j.anai.2022.03.006. [PMID: 35288274] - Xiaojing Ma, Tong Wang, Zequan Yu, Junqian Shao, Jun Chu, Huixia Zhu, Risheng Yao. Formulation and Physicochemical and Biological Characterization of Etoposide-Loaded Submicron Emulsions with Biosurfactant of Sophorolipids.
AAPS PharmSciTech.
2022 Jul; 23(6):181. doi:
10.1208/s12249-022-02329-2. [PMID: 35773548] - Nicholas A Turner, Allan Xu, Smitha Zaharoff, Thomas L Holland, Thomas P Lodise. Determination of plasma protein binding of dalbavancin.
The Journal of antimicrobial chemotherapy.
2022 06; 77(7):1899-1902. doi:
10.1093/jac/dkac131. [PMID: 35488862] - Hannah Dane, Anastasios Koidis, Linda D Stewart, Irene R Grant. Optimization of the composition of a solid culture medium for Mycobacterium avium subsp. paratuberculosis using factorial design and response surface methodology.
Journal of applied microbiology.
2022 Jun; 132(6):4252-4265. doi:
10.1111/jam.15517. [PMID: 35261128] - Shahla Shahsavandi, Mohammad Majid Ebrahimi, Mohammad Bagher Ghadiri, Mohammad Reza Samiee. Tween 80 improves the infectivity of BCL1 cell-adapted infectious bursal disease virus.
Journal of virological methods.
2022 06; 304(?):114502. doi:
10.1016/j.jviromet.2022.114502. [PMID: 35219784] - Magdalena Rys, Małgorzata Miastkowska, Elżbieta Sikora, Anna Łętocha, Agnieszka Krajewska, Agnieszka Synowiec. Bio-Herbicidal Potential of Nanoemulsions with Peppermint Oil on Barnyard Grass and Maize.
Molecules (Basel, Switzerland).
2022 May; 27(11):. doi:
10.3390/molecules27113480. [PMID: 35684420] - Xueyi Xue, Jiang Wang, Diwakar Shukla, Lily S Cheung, Li-Qing Chen. When SWEETs Turn Tweens: Updates and Perspectives.
Annual review of plant biology.
2022 05; 73(?):379-403. doi:
10.1146/annurev-arplant-070621-093907. [PMID: 34910586] - Andrey V Kustov, Philipp K Morshnev, Natal'ya V Kukushkina, Nataliya L Smirnova, Dmitry B Berezin, Dmitry R Karimov, Olga V Shukhto, Tatyana V Kustova, Dmitry V Belykh, Marina V Mal'shakova, Vladimir P Zorin, Tatyana E Zorina. Solvation, Cancer Cell Photoinactivation and the Interaction of Chlorin Photosensitizers with a Potential Passive Carrier Non-Ionic Surfactant Tween 80.
International journal of molecular sciences.
2022 May; 23(10):. doi:
10.3390/ijms23105294. [PMID: 35628108] - Shuai Guo, Chaoxian Wei, Yaxian Zhu, Yong Zhang. How surfactants affect the depuration of polycyclic aromatic hydrocarbons adsorbed on the mangrove leaf surfaces: insight from an in situ method.
Environmental science and pollution research international.
2022 May; 29(21):31413-31425. doi:
10.1007/s11356-021-18469-0. [PMID: 35001285] - Seyedeh Nesa Rezaeian Shiadeh, Elham Khodaverdi, Mahdi Faal Maleki, Farhad Eisvand, Hamidreza Boujaran, Hassan Zarei, Ramin Vosooghi, Farzin Hadizadeh, Hossein Kamali. Lipid-liquid crystals for 2 months controlled risperidone release: In-vitro evaluation and pharmacokinetics in rabbits.
International journal of pharmaceutics.
2022 Apr; 618(?):121649. doi:
10.1016/j.ijpharm.2022.121649. [PMID: 35278600] - Samaneh Fateh Basharzad, Mehrdad Hamidi, Aziz Maleki, Zahra Karami, Hamed Mohamadpour, Mohammad Reza Saghatchi Zanjani. Polysorbate-coated mesoporous silica nanoparticles as an efficient carrier for improved rivastigmine brain delivery.
Brain research.
2022 04; 1781(?):147786. doi:
10.1016/j.brainres.2022.147786. [PMID: 35041841] - Igor Kevin Mkam Tsengam, Marzhana Omarova, Elizabeth G Kelley, Alon McCormick, Geoffrey D Bothun, Srinivasa R Raghavan, Vijay T John. Transformation of Lipid Vesicles into Micelles by Adding Nonionic Surfactants: Elucidating the Structural Pathway and the Intermediate Structures.
The journal of physical chemistry. B.
2022 03; 126(11):2208-2216. doi:
10.1021/acs.jpcb.1c09685. [PMID: 35286100] - M Koroleva, I Portnaya, E Mischenko, I Abutbul-Ionita, L Kolik-Shmuel, D Danino. Solid lipid nanoparticles and nanoemulsions with solid shell: Physical and thermal stability.
Journal of colloid and interface science.
2022 Mar; 610(?):61-69. doi:
10.1016/j.jcis.2021.12.010. [PMID: 34922082] - Kristen Holbrook, Dina Andrews, Wes Sutherland, Aldo Coppi, Shane Barry, Max Escamilla, Simon Authier, Loїs Miraucourt, Fang Xie, Brooke Rock, Jeanine Bussiere. Threshold for Anaphylactoid Reaction to Polysorbate 80 in Canines.
International journal of toxicology.
2022 Mar; 41(2):89-98. doi:
10.1177/10915818211063478. [PMID: 35337210] - Guilherme L Alves, Fernanda V Teixeira, Priscila Bianca Rodrigues da Rocha, Anna Paula Krawczyk-Santos, Lígia Marquez Andrade, Marcilio Cunha-Filho, Ricardo N Marreto, Stephânia F Taveira. Preformulation and characterization of raloxifene-loaded lipid nanoparticles for transdermal administration.
Drug delivery and translational research.
2022 03; 12(3):526-537. doi:
10.1007/s13346-021-00949-y. [PMID: 33682031] - Mylène Pouliot, Jeanine Bussiere, Aldo Coppi, Kristen Holbrook, Amy Shelton, Samantha Sparapani, Jonathan Maher, Tanja S Zabka, Emmanuel Boulay, Simon Authier. Polysorbate 80-Induced Anaphylactoid Reaction and the Effects on Cardiovascular Function: Dose Threshold and Species Comparison.
International journal of toxicology.
2022 Mar; 41(2):99-107. doi:
10.1177/10915818211072780. [PMID: 35245984] - Stephanie V MacWilliams, Damien A Sebben, Andrew J Clulow, James K Ferri, Graeme Gillies, Matt Golding, Ben J Boyd, David A Beattie, Marta Krasowska. The effect of emulsifier type on the secondary crystallisation of monoacylglycerol and triacylglycerols in model dairy emulsions.
Journal of colloid and interface science.
2022 Feb; 608(Pt 3):2839-2848. doi:
10.1016/j.jcis.2021.11.008. [PMID: 34801239] - Joachim Schuster, Vinay Kamuju, Roman Mathaes. Fate of antibody and polysorbate particles in a human serum model.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2022 Feb; 171(?):72-79. doi:
10.1016/j.ejpb.2021.12.005. [PMID: 34920132] - Stéphane Pillet, Prabhu S Arunachalam, Guadalupe Andreani, Nadia Golden, Jane Fontenot, Pyone Pyone Aye, Katharina Röltgen, Gabrielle Lehmicke, Philipe Gobeil, Charlotte Dubé, Sonia Trépanier, Nathalie Charland, Marc-André D'Aoust, Kasi Russell-Lodrigue, Christopher Monjure, Robert V Blair, Scott D Boyd, Rudolf P Bohm, Jay Rappaport, François Villinger, Nathalie Landry, Bali Pulendran, Brian J Ward. Safety, immunogenicity, and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in nonhuman primates.
Cellular & molecular immunology.
2022 02; 19(2):222-233. doi:
10.1038/s41423-021-00809-2. [PMID: 34983950] - Priya Sellaturay, Padmalal Gurugama, Verah Harper, Tom Dymond, Pamela Ewan, Shuaib Nasser. The Polysorbate containing AstraZeneca COVID-19 vaccine is tolerated by polyethylene glycol (PEG) allergic patients.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
2022 01; 52(1):12-17. doi:
10.1111/cea.14064. [PMID: 34822190] - Charlotte Dubé, Sarah Paris-Robidas, Iryna Primakova, Eric Destexhe, Brian J Ward, Nathalie Landry, Sonia Trépanier. Lack of effects on female fertility or pre- and postnatal development of offspring in rats after exposure to AS03-adjuvanted recombinant plant-derived virus-like particle vaccine candidate for COVID-19.
Reproductive toxicology (Elmsford, N.Y.).
2022 01; 107(?):69-80. doi:
10.1016/j.reprotox.2021.11.006. [PMID: 34838689] - Shailendra Chouhan, Lalit Singh Chauhan. Effect of Surfactant Chain Length on Emulsification Dynamics of Self Emulsifying Formulation of Poorly Soluble Drug.
Current drug delivery.
2022; 19(8):874-888. doi:
10.2174/1567201818666210727092639. [PMID: 34315366] - Taya Carpenter, Justin Konig, Jillian Hochfelder, Subhadra Siegel, Melissa Gans. Polyethylene glycol and polysorbate testing in 12 patients before or after coronavirus disease 2019 vaccine administration.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
2022 01; 128(1):99-101. doi:
10.1016/j.anai.2021.10.009. [PMID: 34648975] - Xingyu Lu, Mingyue Li, Freddy A Arce, Jing Ling, Nico Setiawan, Yaqiang Wang, Xiaohuo Shi, Heather R Campbell, Matthew J Nethercott, Wei Xu, Eric J Munson, Patrick J Marsac, Yongchao Su. Mechanistic Investigation of Drug Supersaturation in the Presence of Polysorbates as Solubilizing Additives by Solution Nuclear Magnetic Resonance Spectroscopy.
Molecular pharmaceutics.
2021 12; 18(12):4310-4321. doi:
10.1021/acs.molpharmaceut.1c00477. [PMID: 34761934] - Amali G Guruge, Dallas B Warren, Hassan Benameur, Leigh Ford, Hywel D Williams, Vincent Jannin, Colin W Pouton, David K Chalmers. Computational and Experimental Models of Type III Lipid-Based Formulations of Loratadine Containing Complex Nonionic Surfactants.
Molecular pharmaceutics.
2021 12; 18(12):4354-4370. doi:
10.1021/acs.molpharmaceut.1c00547. [PMID: 34807627] - Zhengnan Jia, Miaomiao Ding, Masahito Nakano, Kunqi Hong, Ruidong Huang, Dieter Becker, Jane Glazebrook, Fumiaki Katagiri, Xiaowei Han, Kenichi Tsuda. Letter to the Editor: DNA Purification-Free PCR from Plant Tissues.
Plant & cell physiology.
2021 12; 62(10):1503-1505. doi:
10.1093/pcp/pcab120. [PMID: 34320213] - Brae Anne McArthur, Sheri Madigan, Daphne J Korczak. Tweens are not teens: the problem of amalgamating broad age groups when making pandemic recommendations.
Canadian journal of public health = Revue canadienne de sante publique.
2021 12; 112(6):984-987. doi:
10.17269/s41997-021-00585-6. [PMID: 34716572] - Noha M Badawi, Mona A Elkafrawy, Rania M Yehia, Dalia A Attia. Clinical comparative study of optimized metronidazole loaded lipid nanocarrier vaginal emulgel for management of bacterial vaginosis and its recurrence.
Drug delivery.
2021 Dec; 28(1):814-825. doi:
10.1080/10717544.2021.1912211. [PMID: 33899634] - Toon Ieven, Thomas Van Weyenbergh, Martijn Vandebotermet, David Devolder, Christine Breynaert, Rik Schrijvers. Tolerability of polysorbate 80-containing COVID-19 vaccines in confirmed polyethylene glycol-allergic patients.
The journal of allergy and clinical immunology. In practice.
2021 12; 9(12):4470-4472.e1. doi:
10.1016/j.jaip.2021.09.039. [PMID: 34626857] - Xuanxuan Nian, Jiayou Zhang, Tao Deng, Jing Liu, Zheng Gong, Chuanshuo Lv, Luyao Yao, Junying Li, Shihe Huang, Xiaoming Yang. AddaVax Formulated with PolyI:C as a Potential Adjuvant of MDCK-based Influenza Vaccine Enhances Local, Cellular, and Antibody Protective Immune Response in Mice.
AAPS PharmSciTech.
2021 Nov; 22(8):270. doi:
10.1208/s12249-021-02145-0. [PMID: 34766215] - Sarunya Tuntiyasawasdikul, Bungorn Sripanidkulchai. Curcuma comosa loaded transfersomal gel for transdermal application: formulation, in vitro and in vivo evaluation.
Drug development and industrial pharmacy.
2021 Nov; 47(11):1824-1834. doi:
10.1080/03639045.2022.2064486. [PMID: 35403530] - Esmat Rousta, Akihiko Oka, Bo Liu, Jeremy Herzog, Aadra P Bhatt, Jeremy Wang, Mohammad B Habibi Najafi, Ryan Balfour Sartor. The Emulsifier Carboxymethylcellulose Induces More Aggressive Colitis in Humanized Mice with Inflammatory Bowel Disease Microbiota Than Polysorbate-80.
Nutrients.
2021 Oct; 13(10):. doi:
10.3390/nu13103565. [PMID: 34684567] - Marlene Costa, Sonia Losada-Barreiro, Fátima Paiva-Martins, Carlos Bravo-Díaz. Effects of Surfactant Volume Fraction on the Antioxidant Efficiency and on The Interfacial Concentrations of Octyl and Tetradecyl p-Coumarates in Corn Oil-in-Water Emulsions.
Molecules (Basel, Switzerland).
2021 Oct; 26(19):. doi:
10.3390/molecules26196058. [PMID: 34641602] - Mitchell M Pitlick, Miguel A Park, Alexei Gonzalez-Estrada, Sergio E Chiarella. Biphasic anaphylaxis after first dose of messenger RNA coronavirus disease 2019 vaccine with positive polysorbate 80 skin testing result.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
2021 10; 127(4):498-499. doi:
10.1016/j.anai.2021.07.020. [PMID: 34343674] - Keith J Chappell, Francesca L Mordant, Zheyi Li, Danushka K Wijesundara, Paula Ellenberg, Julia A Lackenby, Stacey T M Cheung, Naphak Modhiran, Michael S Avumegah, Christina L Henderson, Kym Hoger, Paul Griffin, Jillian Bennet, Luca Hensen, Wuji Zhang, Thi H O Nguyen, Sara Marrero-Hernandez, Kevin J Selva, Amy W Chung, Mai H Tran, Peter Tapley, James Barnes, Patrick C Reading, Suellen Nicholson, Stavroula Corby, Thomas Holgate, Bruce D Wines, P Mark Hogarth, Katherine Kedzierska, Damian F J Purcell, Charani Ranasinghe, Kanta Subbarao, Daniel Watterson, Paul R Young, Trent P Munro. Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial.
The Lancet. Infectious diseases.
2021 10; 21(10):1383-1394. doi:
10.1016/s1473-3099(21)00200-0. [PMID: 33887208] - Sonja Schertel, Sharareh Salar-Behzadi, Julia Karrer, Peter Laggner, Andreas Zimmer. Impact of polysorbate 65 on tripalmitin crystal growth and release stability of hot melt coated multiparticulate systems.
International journal of pharmaceutics.
2021 Sep; 607(?):120970. doi:
10.1016/j.ijpharm.2021.120970. [PMID: 34363917] - Toshinori Shimanouchi, Tetsuya Hayashi, Kazuki Toramoto, Saki Fukuma, Keita Hayashi, Kazuma Yasuhara, Yukitaka Kimura. Microfluidic and hydrothermal preparation of vesicles using sorbitan monolaurate/polyoxyethylene (20) sorbitan monolaurate (Span 20/Tween 20).
Colloids and surfaces. B, Biointerfaces.
2021 Sep; 205(?):111836. doi:
10.1016/j.colsurfb.2021.111836. [PMID: 34058692] - Lingbin Yan, Zhulan Zhang, Yin Zhang, Huangjian Yang, Guanrong Qiu, Desen Wang, Yunyang Lian. Improvement of tacrolimus production in Streptomyces tsukubaensis by mutagenesis and optimization of fermentation medium using Plackett-Burman design combined with response surface methodology.
Biotechnology letters.
2021 Sep; 43(9):1765-1778. doi:
10.1007/s10529-021-03144-8. [PMID: 34021830] - Matthew Greenhawt, Marcus Shaker, David B K Golden. PEG/Polysorbate Skin Testing Has No Utility in the Assessment of Suspected Allergic Reactions to SARS-CoV-2 Vaccines.
The journal of allergy and clinical immunology. In practice.
2021 09; 9(9):3321-3322. doi:
10.1016/j.jaip.2021.06.025. [PMID: 34393075] - Patrycja Szumała, Aneta Pacyna-Kuchta, Andrzej Wasik. Proteolysis of whey protein isolates in nanoemulsion systems: Impact of nanoemulsification and additional synthetic emulsifiers.
Food chemistry.
2021 Jul; 351(?):129356. doi:
10.1016/j.foodchem.2021.129356. [PMID: 33647693] - Robert G Strickley, William J Lambert. A review of Formulations of Commercially Available Antibodies.
Journal of pharmaceutical sciences.
2021 07; 110(7):2590-2608.e56. doi:
10.1016/j.xphs.2021.03.017. [PMID: 33789155] - Min Hyeock Lee, Tae-Eun Kim, Hae Won Jang, Yong Gi Chun, Bum-Keun Kim. Physical and turbidimetric properties of cholecalciferol- and menaquinone-loaded lipid nanocarriers emulsified with polysorbate 80 and soy lecithin.
Food chemistry.
2021 Jun; 348(?):129099. doi:
10.1016/j.foodchem.2021.129099. [PMID: 33503533] - Mitchell M Pitlick, Andrea N Sitek, Susan A Kinate, Avni Y Joshi, Miguel A Park. Polyethylene glycol and polysorbate skin testing in the evaluation of coronavirus disease 2019 vaccine reactions: Early report.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
2021 06; 126(6):735-738. doi:
10.1016/j.anai.2021.03.012. [PMID: 33775902] - Yu-Hsiang Lin, Chi-Chung Wang, Ying-Hung Lin, Bing-Huei Chen. Preparation of Catechin Nanoemulsion from Oolong Tea Leaf Waste and Its Inhibition of Prostate Cancer Cells DU-145 and Tumors in Mice.
Molecules (Basel, Switzerland).
2021 May; 26(11):. doi:
10.3390/molecules26113260. [PMID: 34071530] - Min Liu, Chen Yang, Enchao Liu, Fang Zhang, Xianghong Meng, Bingjie Liu. Effect of environmental stresses on physicochemical properties of ALA oil-in-water nanoemulsion system prepared by emulsion phase inversion.
Food chemistry.
2021 May; 343(?):128475. doi:
10.1016/j.foodchem.2020.128475. [PMID: 33168257]