Oryzanol A (BioDeep_00000620085)
Main id: BioDeep_00000395619
PANOMIX_OTCML-2023
代谢物信息卡片
7,7,12,16-tetramethyl-15-(6-methylhept-5-en-2-yl)pentacyclo[9.7.0.0^{1,3}.0^{3,8}.0^{12,16}]octadecan-6-yl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
化学式: C40H58O4 (602.4334868)
中文名称: 谷维素
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(CCC=C(C)C)C1CCC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)C)OC(=O)C=CC6=CC(=C(C=C6)O)OC)C)C
InChI: InChI=1S/C40H58O4/c1-26(2)10-9-11-27(3)29-18-20-38(7)33-16-15-32-36(4,5)34(19-21-39(32)25-40(33,39)23-22-37(29,38)6)44-35(42)17-13-28-12-14-30(41)31(24-28)43-8/h10,12-14,17,24,27,29,32-34,41H,9,11,15-16,18-23,25H2,1-8H3/b17-13+
描述信息
D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents
D005765 - Gastrointestinal Agents > D000897 - Anti-Ulcer Agents
D009676 - Noxae > D000963 - Antimetabolites
From rice bran oil (Oryza sativa). Oryzanol A is found in cereals and cereal products, rice, and fats and oils.
γ-Oryzanol is a potent DNA methyltransferases (DNMTs) inhibitor in the striatum of mice. γ-Oryzanol significantly inhibits the activities of DNMT1 (IC50=3.2 μM), DNMT3a (IC50=22.3 μM).
同义名列表
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:176202
- PubChem: 12313778
- Metlin: METLIN91095
- foodb: FDB014675
- CAS: 11042-64-1
- medchemexpress: HY-B2194
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Shujie Wang, Yuyue Qin, Yaping Liu, Guoqin Liu, Guiguang Cheng, Thanapop Soteyome. Controlling release of astaxanthin in β-sitosterol oleogel-based emulsions via different self-assembled mechanisms and composition of the oleogelators.
Food research international (Ottawa, Ont.).
2024 Jun; 186(?):114350. doi:
10.1016/j.foodres.2024.114350. [PMID: 38729698] - Juliana Silva Siqueira, Jessica Leite Garcia, Artur Junio Togneri Ferron, Fernando Moreto, Luis Eduardo Sormani, Mariane Rovero Costa, Thiago Luiz Novaga Palacio, Gisele Alborghetti Nai, Giancarlo Aldini, Fabiane Valentini Francisqueti-Ferron, Camila Renata Correa, Alfonsina D'Amato. Proteomic study of gamma-oryzanol preventive effect on a diet-induced non-alcoholic fatty liver disease model.
The Journal of nutritional biochemistry.
2024 May; 127(?):109607. doi:
10.1016/j.jnutbio.2024.109607. [PMID: 38432453] - Sapna I, A Jayadeep. Enzyme-treated red rice (Oryza sativa L.) bran extracts mitigate inflammatory markers in RAW 264.7 macrophage cells and exhibit anti-inflammatory efficacy greater/comparable to ferulic acid, catechin, γ-tocopherol, and γ-oryzanol.
Journal of ethnopharmacology.
2024 Apr; 323(?):117616. doi:
10.1016/j.jep.2023.117616. [PMID: 38142877] - Hai-Long Zhang, Zhi-Xian Wang, Kun-Li Wang, Jing Du, Jun-Bo He, Wei-Nong Zhang. Lipid concomitant γ-oryzanol decreased oil absorbency of French fries by changing the microstructure of French fries and physical properties of frying oil.
Journal of the science of food and agriculture.
2024 Apr; 104(6):3246-3255. doi:
10.1002/jsfa.13211. [PMID: 38081762] - Zi-Han Dai, Chen-Cheng Zhou, Cai-Yu Yu, Cheng-Jie Qian, Shu-Qing Jin, Shi-Qi Du, Yi-Yun Lv, Chen Jin, Gang Zheng, Yu Zhan. Gamma-oryzanol alleviates osteoarthritis development by targeting Keap1-Nrf2 binding to interfere with chondrocyte ferroptosis.
International immunopharmacology.
2024 Feb; 128(?):111469. doi:
10.1016/j.intimp.2023.111469. [PMID: 38211480] - Zhu Zhu, Ying Xu, Yiwen Guo, Ruijie Liu, Ming Chang, Xingguo Wang. Antioxidant interaction between α-tocopherol and γ-oryzanol in HepG2 cells.
Food & function.
2024 Jan; 15(2):992-1003. doi:
10.1039/d3fo03727d. [PMID: 38179649] - Pan Gao, Ying Liu, Shu Wang, Chuanyang Huang, Wu Zhong, Jiaojiao Yin, Chuanrong Hu, Dongping He, Xingguo Wang. Effects of different oleogelators on the structural properties and composition of iron walnut-oil oleogels.
Ultrasonics sonochemistry.
2024 Jan; 102(?):106729. doi:
10.1016/j.ultsonch.2023.106729. [PMID: 38103368] - Hashem Andishmand, Mohammad Yousefi, Nahideh Jafari, Sodeif Azadmard-Damirchi, Aziz Homayouni-Rad, Mohammadali Torbati, Hamed Hamishehkar. Designing and fabrication of colloidal nano-phytosomes with gamma-oryzanol and phosphatidylcholine for encapsulation and delivery of polyphenol-rich extract from pomegranate peel.
International journal of biological macromolecules.
2024 Jan; 256(Pt 2):128501. doi:
10.1016/j.ijbiomac.2023.128501. [PMID: 38040148] - Manisha Thapa, Lei Liu, Bronwyn J Barkla, Tobias Kretzschmar, Suzy Y Rogiers, Terry J Rose. Accumulation patterns of anthocyanin and γ-oryzanol during black rice grain development.
PloS one.
2024; 19(5):e0302745. doi:
10.1371/journal.pone.0302745. [PMID: 38776277] - Bahareh Nikooyeh, Azizollaah Zargaraan, Samira Ebrahimof, Ali Kalayi, Maliheh Zahedirad, Hootan Yazdani, Marjan Rismanchi, Taher Karami, Marzieh Khazraei, Ali Jafarpour, Tirang R Neyestani. Daily consumption of γ-oryzanol-fortified canola oil, compared with unfortified canola and sunflower oils, resulted in a better improvement of certain cardiometabolic biomarkers of adult subjects with type 2 diabetes: a randomized controlled clinical trial.
European journal of medical research.
2023 Oct; 28(1):416. doi:
10.1186/s40001-023-01409-8. [PMID: 37817285] - Salisa Chumsantea, Apiwat Jiruttisakul, Akkaradech Nakornsadet, Piraporn Sombutsuwan, Kornkanok Aryusuk. Simultaneous Determination of Vitamin E and γ-Oryzanol in Rice Bran Oil via HPSEC-PDA without Sample Pretreatment.
Journal of oleo science.
2023; 72(7):655-665. doi:
10.5650/jos.ess22257. [PMID: 37380482] - Bobo Sun, Pan Gao, Hui Yu, Zhiwen Dong, Jiaojiao Yin, Wu Zhong, Chuanrong Hu, Dongping He, Xingguo Wang. Optimization of Composite Decolorizer Efficacy Based on Decolorization Efficiency, Toxicity, and Nutritional Value of Rice Bran Oil.
Journal of oleo science.
2023; 72(8):755-765. doi:
10.5650/jos.ess23050. [PMID: 37532566] - Ashwag H Alwadani, Soheir A Almasri, Amal A Aloud, Nawal A Albadr, Ghedeir M Alshammari, Mohammed Abdo Yahya. The Synergistic Protective Effect of γ-Oryzanol (OZ) and N-Acetylcysteine (NAC) against Experimentally Induced NAFLD in Rats Entails Hypoglycemic, Antioxidant, and PPARα Stimulatory Effects.
Nutrients.
2022 Dec; 15(1):. doi:
10.3390/nu15010106. [PMID: 36615764] - Ying Xu, Yiwen Guo, Ruru Liu, Ruijie Liu, Ming Chang. In vitro digestion of binary mixture of α-tocopherol and γ-oryzanol in oil-in-water emulsion: Changes in stability and antioxidant potential.
Food research international (Ottawa, Ont.).
2022 09; 159(?):111606. doi:
10.1016/j.foodres.2022.111606. [PMID: 35940803] - Wenli Sun, Jin Shi, Jun Hong, Guochao Zhao, Wensheng Wang, Dabing Zhang, Wei Zhang, Jianxin Shi. Natural variation and underlying genetic loci of γ-oryzanol in Asian cultivated rice seeds.
The plant genome.
2022 09; 15(3):e20201. doi:
10.1002/tpg2.20201. [PMID: 35762101] - Sisi Yan, Jihong Chen, Lingfeng Zhu, Tianyi Guo, Dandan Qin, Zuomin Hu, Shuai Han, Yaping Zhou, Otobang Donald Akan, Ji Wang, Feijun Luo, Qinlu Lin. Oryzanol Attenuates High Fat and Cholesterol Diet-Induced Hyperlipidemia by Regulating the Gut Microbiome and Amino Acid Metabolism.
Journal of agricultural and food chemistry.
2022 Jun; 70(21):6429-6443. doi:
10.1021/acs.jafc.2c00885. [PMID: 35587527] - Sisi Yan, Jihong Chen, Lingfeng Zhu, Tianyi Guo, Dandan Qin, Zuomin Hu, Shuai Han, Ji Wang, Froilan Bernard Matias, Lixin Wen, Feijun Luo, Qinlu Lin. Oryzanol alleviates high fat and cholesterol diet-induced hypercholesterolemia associated with the modulation of the gut microbiota in hamsters.
Food & function.
2022 Apr; 13(8):4486-4501. doi:
10.1039/d1fo03464b. [PMID: 35348138] - Abouzar Najafi, Hossein Daghigh-Kia, Mahdieh Mehdipour, Hossein Mohammadi, Hamed Hamishehkar. Comparing the effect of rooster semen extender supplemented with gamma-oryzanol and its nano form on post-thaw sperm quality and fertility.
Poultry science.
2022 Mar; 101(3):101637. doi:
10.1016/j.psj.2021.101637. [PMID: 35038650] - Mohamad Reza Toorani, Mohammad-Taghi Golmakani. Effect of triacylglycerol structure on the antioxidant activity of γ-oryzanol.
Food chemistry.
2022 Feb; 370(?):130974. doi:
10.1016/j.foodchem.2021.130974. [PMID: 34500298] - Atita Panyathep, Khanittha Punturee, Teera Chewonarin. Gamma-Oryzanol-Rich Fraction from Purple Rice Extract Attenuates Lipopolysaccharide-Stimulated Inflammatory Responses, Migration and VEGFA Production in SW480 Cells via Modulation of TLR4 and NF-κB Pathways.
Nutrition and cancer.
2022; 74(6):2254-2264. doi:
10.1080/01635581.2021.2002921. [PMID: 34766845] - Yi Shen, Dianxing Wu, Vincenzo Fogliano, Nicoletta Pellegrini. Rice varieties with a high endosperm lipid content have reduced starch digestibility and increased γ-oryzanol bioaccessibility.
Food & function.
2021 Nov; 12(22):11547-11556. doi:
10.1039/d1fo03039f. [PMID: 34708854] - Somaiyeh Maleki, AmirAhmad Arabzadeh, Kazem Nejati, Farzaneh Fathi. Exploring The Interactions of a Natural Gamma-Oryzanol with Human Serum Albumin: Surface Plasmon Resonance, Fluorescence, and Molecular Modeling Studies.
Drug research.
2021 Nov; 71(9):520-527. doi:
10.1055/a-1533-2941. [PMID: 34331299] - Letícia Mattei, Fabiane Valentini Francisqueti-Ferron, Jéssica Leite Garcia, Artur Junio Togneri Ferron, Carol Cristina Vágula de Almeida Silva, Cristina Schmitt Gregolin, Erika Tiemi Nakandakare-Maia, Janaína das Chagas Paixão Silva, Fernando Moreto, Igor Otávio Minatel, Camila Renata Corrêa. Antioxidant and anti-inflammatory properties of gamma- oryzanol attenuates insulin resistance by increasing GLUT- 4 expression in skeletal muscle of obese animals.
Molecular and cellular endocrinology.
2021 11; 537(?):111423. doi:
10.1016/j.mce.2021.111423. [PMID: 34400258] - Fabiane Valentini Francisqueti-Ferron, Artur Junio Togneri Ferron, Alessandra Altomare, Jéssica Leite Garcia, Fernando Moreto, Ana Lúcia A Ferreira, Igor Otávio Minatel, Giancarlo Aldini, Camila Renata Corrêa. Gamma-oryzanol reduces renal inflammation and oxidative stress by modulating AGEs/RAGE axis in animals submitted to high sugar-fat diet.
Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia.
2021 Oct; 43(4):460-469. doi:
10.1590/2175-8239-jbn-2021-0002. [PMID: 34174064] - Mariangela Hoffmann Bruscatto, Deborah Murowaniecki Otero, Vanessa Ribeiro Pestana-Bauer, Alexandre Lorini, Carla Rosane Barboza Mendonça, Rui Carlos Zambiazi. Study of the thermal stability of γ-oryzanol present in rice bran oil over time.
Journal of the science of food and agriculture.
2021 Oct; 101(13):5715-5720. doi:
10.1002/jsfa.11179. [PMID: 33682139] - Ewa Młodzińska-Michta, Weronika Korzeniowska. Gamma-oryzanol as an example of a complex of phytosterol esters and ferulic acid with broad biological activity.
Postepy biochemii.
2021 09; 67(3):205-211. doi:
10.18388/pb.2021_391. [PMID: 34894391] - Tapan Behl, Sachin Kumar, Aayush Sehgal, Sukhbir Singh, Shilpa Kumari, Mihaela Cristina Brisc, Mihai Alexandru Munteanu, Ciprian Brisc, Camelia Liana Buhas, Claudia Judea-Pusta, Camelia Liana Buhas, Claudia Judea-Pusta, Delia Carmen Nistor-Cseppento, Simona Bungau. Rice bran, an off-shoot to newer therapeutics in neurological disorders.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2021 Aug; 140(?):111796. doi:
10.1016/j.biopha.2021.111796. [PMID: 34098194] - Ruru Liu, Ying Xu, Ming Chang, Lin Tang, Mengyao Lu, Ruijie Liu, Qingzhe Jin, Xingguo Wang. Antioxidant interaction of α-tocopherol, γ-oryzanol and phytosterol in rice bran oil.
Food chemistry.
2021 May; 343(?):128431. doi:
10.1016/j.foodchem.2020.128431. [PMID: 33131960] - Mustafa Munir Mustafa Dahleh, Stífani Machado Araujo, Vandreza Cardoso Bortolotto, Franciane Cabral Pinheiro, Márcia Rósula Poetini, Elize Aparecida Santos Musachio, Luana Barreto Meichtry, Shanda de Freitas Couto, Marina Prigol. Exercise associated with γ-oryzanol supplementation suppresses oxidative stress and prevents changes in locomotion in Drosophila melanogaster.
Free radical research.
2021 Feb; 55(2):198-209. doi:
10.1080/10715762.2021.1895992. [PMID: 33655816] - Fabiane Valentini Francisqueti-Ferron, Jéssica Leite Garcia, Artur Junio Togneri Ferron, Erika Tiemi Nakandakare-Maia, Cristina Schmitt Gregolin, Janaina Paixão das Chagas Silva, Klinsmann Carolo Dos Santos, Ângelo Thompson Colombo Lo, Juliana Silva Siqueira, Letícia de Mattei, Bruno Henrique de Paula, Felipe Sarzi, Carol Cristina Vágula de Almeida Silva, Fernando Moreto, Mariane Róvero Costa, Ana Lucia A Ferreira, Igor Otávio Minatel, Camila Renata Corrêa. Gamma-oryzanol as a potential modulator of oxidative stress and inflammation via PPAR-y in adipose tissue: a hypothetical therapeutic for cytokine storm in COVID-19?.
Molecular and cellular endocrinology.
2021 01; 520(?):111095. doi:
10.1016/j.mce.2020.111095. [PMID: 33253762] - Elham Ramazani, Maryam Akaberi, Seyed Ahmad Emami, Zahra Tayarani-Najaran. Biological and Pharmacological Effects of Gamma-oryzanol: An Updated Review of the Molecular Mechanisms.
Current pharmaceutical design.
2021; 27(19):2299-2316. doi:
10.2174/1381612826666201102101428. [PMID: 33138751] - Yichao Du, Furui Zhong, Huanli Cheng, Tongxi Li, Yifan Chen, Peng Tan, Meizhou Huang, Tiancheng Liang, Yu Liu, Xianming Xia, Wenguang Fu. The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Oxidative medicine and cellular longevity.
2021; 2021(?):4628050. doi:
10.1155/2021/4628050. [PMID: 34512864] - Piraporn Sombutsuwan, Apiwat Jirattisakul, Akkaradech Nakornsadet, Saengchai Akepratumchai, Salisa Chumsantea, Siriluck Pojjanapornpun, Supathra Lilitchan, Kanit Krisnangkura, Kornkanok Aryusuk. A Simple and Efficient Method for Synthesis and Extraction of Ethyl Ferulate from γ-Oryzanol.
Journal of oleo science.
2021; 70(6):757-767. doi:
10.5650/jos.ess20180. [PMID: 34078757] - Atita Panyathep, Teera Chewonarin. Inhibitory effect of a gamma-oryzanol-rich fraction from purple rice extract on lipopolysaccharide-induced metastasis in human colon cancer cells.
Journal of food biochemistry.
2020 12; 44(12):e13487. doi:
10.1111/jfbc.13487. [PMID: 33029825] - Lulu Dong, Muwen Lv, Xiangyang Gao, Luping Zhang, Michael Rogers, Yong Cao, Yaqi Lan. In vitro gastrointestinal digestibility of phytosterol oleogels: influence of self-assembled microstructures on emulsification efficiency and lipase activity.
Food & function.
2020 Nov; 11(11):9503-9513. doi:
10.1039/d0fo01642j. [PMID: 32955534] - S Singh, C Kothari, M Patel, S Panchal. Novel bio-analytical technique for estimation of gamma oryzanol in rat plasma and brain homogenate using HPLC.
Annales pharmaceutiques francaises.
2020 Nov; 78(6):515-524. doi:
10.1016/j.pharma.2020.07.003. [PMID: 32681901] - Sonia Calligaris, Marilisa Alongi, Paolo Lucci, Monica Anese. Effect of different oleogelators on lipolysis and curcuminoid bioaccessibility upon in vitro digestion of sunflower oil oleogels.
Food chemistry.
2020 Jun; 314(?):126146. doi:
10.1016/j.foodchem.2019.126146. [PMID: 31954944] - Hui-Li Lin, Shih-Hsiung Lin, Kuo-Ping Shen, Hua-Chen Chan, Yu-Hsiu Tseng, Hsueh-Wei Yen, Shi-Hui Law, Liang-Yin Ke. Efficiency comparison of PGBR extract and γ-oryzanol in antioxidative stress and anti-inflammatory properties against metabolic syndrome.
Journal of food biochemistry.
2020 02; 44(2):e13129. doi:
10.1111/jfbc.13129. [PMID: 31846084] - Lin Huang, Weiwei Jiang, Lijuan Zhu, Chaoyang Ma, Zhaoping Ou, Chenxi Luo, Jing Wu, Lixin Wen, Zhuliang Tan, Jine Yi. γ-Oryzanol suppresses cell apoptosis by inhibiting reactive oxygen species-mediated mitochondrial signaling pathway in H2O2-stimulated L02 cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2020 Jan; 121(?):109554. doi:
10.1016/j.biopha.2019.109554. [PMID: 31678753] - Dan Li, Chao Zhang, Ai-Wu Zhang, Li-Li Qian, Dong-Jie Zhang. Changes of liposome and antioxidant activity in immature rice during seed development.
Journal of food science.
2020 Jan; 85(1):86-95. doi:
10.1111/1750-3841.14967. [PMID: 31945205] - Laura A Calvo-Castro, Nadine Sus, Christina Schiborr, Anja Bosy-Westphal, Maria Luisa Duran, Doris Fesenmeyer, Gerhard Fesenmeyer, Jan Frank. Pharmacokinetics of vitamin E, γ-oryzanol, and ferulic acid in healthy humans after the ingestion of a rice bran-enriched porridge prepared with water or with milk.
European journal of nutrition.
2019 Aug; 58(5):2099-2110. doi:
10.1007/s00394-018-1770-6. [PMID: 29978378] - Warangkana Pornputtapitak, Jaturavit Pantakitcharoenkul, Veerawat Teeranachaideekul, Kitiphat Sinthiptharakoon, Chaweewan Sapcharoenkun, Benchaporn Meemuk. Effect of Oil Content on Physiochemical Characteristics of γ-Oryzanol-Loaded Nanostructured Lipid Carriers.
Journal of oleo science.
2019 Aug; 68(8):699-707. doi:
10.5650/jos.ess18127. [PMID: 31292337] - Xiao-Xuan Guo, Zhu Zeng, Yong-Zhong Qian, Jing Qiu, Kai Wang, Yong Wang, Bao-Ping Ji, Feng Zhou. Wheat Flour, Enriched with γ-Oryzanol, Phytosterol, and Ferulic Acid, Alleviates Lipid and Glucose Metabolism in High-Fat-Fructose-Fed Rats.
Nutrients.
2019 Jul; 11(7):. doi:
10.3390/nu11071697. [PMID: 31340583] - Sarah A Willett, Casimir C Akoh. Physicochemical Characterization of Yellow Cake Prepared with Structured Lipid Oleogels.
Journal of food science.
2019 Jun; 84(6):1390-1399. doi:
10.1111/1750-3841.14624. [PMID: 31107548] - Takumi Kokumai, Junya Ito, Eri Kobayashi, Naoki Shimizu, Hiroyuki Hashimoto, Takahiro Eitsuka, Teruo Miyazawa, Kiyotaka Nakagawa. Comparison of Blood Profiles of γ-Oryzanol and Ferulic Acid in Rats after Oral Intake of γ-Oryzanol.
Nutrients.
2019 May; 11(5):. doi:
10.3390/nu11051174. [PMID: 31130653] - Ana Castanho, Manuela Lageiro, Ricardo C Calhelha, Isabel C F R Ferreira, Marina Sokovic, Luís M Cunha, Carla Brites. Exploiting the bioactive properties of γ-oryzanol from bran of different exotic rice varieties.
Food & function.
2019 May; 10(5):2382-2389. doi:
10.1039/c8fo02596g. [PMID: 30950464] - Eduarda Escobar, Sabrina Lopes, Cristiano Malavolta, Juliana Bernera Ramalho, Daniele Missio, Hirya Fernandes Pinto, Melina Bucco Soares, Fábio Gallas Leivas, Daniela Dos Santos Brum, Francielli Weber Santos Cibin. Effect of γ-oryzanol on testicular degeneration induced by scrotal insulation in rams.
Theriogenology.
2019 Apr; 128(?):167-175. doi:
10.1016/j.theriogenology.2019.01.041. [PMID: 30772660] - Akkarach Bumrungpert, Rewadee Chongsuwat, Chanchira Phosat, Arisa Butacnum. Rice Bran Oil Containing Gamma-Oryzanol Improves Lipid Profiles and Antioxidant Status in Hyperlipidemic Subjects: A Randomized Double-Blind Controlled Trial.
Journal of alternative and complementary medicine (New York, N.Y.).
2019 Mar; 25(3):353-358. doi:
10.1089/acm.2018.0212. [PMID: 30265563] - Larissa Naida Rosa, Aline Coqueiro, Paulo Henrique Março, Patrícia Valderrama. Thermal rice oil degradation evaluated by UV-Vis-NIR and PARAFAC.
Food chemistry.
2019 Feb; 273(?):52-56. doi:
10.1016/j.foodchem.2018.03.065. [PMID: 30292374] - Piramon Pokkanta, Phumon Sookwong, Manatchanok Tanang, Saranya Setchaiyan, Pittayaporn Boontakham, Sugunya Mahatheeranont. Simultaneous determination of tocols, γ-oryzanols, phytosterols, squalene, cholecalciferol and phylloquinone in rice bran and vegetable oil samples.
Food chemistry.
2019 Jan; 271(?):630-638. doi:
10.1016/j.foodchem.2018.07.225. [PMID: 30236726] - Eri Kobayashi, Junya Ito, Naoki Shimizu, Takumi Kokumai, Shunji Kato, Kazue Sawada, Hiroyuki Hashimoto, Takahiro Eitsuka, Teruo Miyazawa, Kiyotaka Nakagawa. Evaluation of γ-oryzanol Accumulation and Lipid Metabolism in the Body of Mice Following Long-Term Administration of γ-oryzanol.
Nutrients.
2019 Jan; 11(1):. doi:
10.3390/nu11010104. [PMID: 30621350] - Salina Akter, Hiroyuki Sasaki, Kazi Rasel Uddin, Yuko Ikeda, Hiroki Miyakawa, Shigenobu Shibata. Anxiolytic effects of γ-oryzanol in chronically- stressed mice are related to monoamine levels in the brain.
Life sciences.
2019 Jan; 216(?):119-128. doi:
10.1016/j.lfs.2018.11.042. [PMID: 30468832] - Giordano Lesma, Andrea Luraghi, Teodora Bavaro, Roberta Bortolozzi, Giulia Rainoldi, Gabriella Roda, Giampietro Viola, Daniela Ubiali, Alessandra Silvani. Phytosterol and γ-Oryzanol Conjugates: Synthesis and Evaluation of their Antioxidant, Antiproliferative, and Anticholesterol Activities.
Journal of natural products.
2018 10; 81(10):2212-2221. doi:
10.1021/acs.jnatprod.8b00465. [PMID: 30360625] - Sara Martillanes, María Concepción Ayuso-Yuste, María Victoria Gil, Raquel Manzano-Durán, Jonathan Delgado-Adámez. Bioavailability, composition and functional characterization of extracts from Oryza sativa L. bran.
Food research international (Ottawa, Ont.).
2018 09; 111(?):299-305. doi:
10.1016/j.foodres.2018.05.057. [PMID: 30007689] - Phumon Sookwong, Sugunya Mahatheeranont. Some Strategies for Utilization of Rice Bran Functional Lipids and Phytochemicals.
Journal of oleo science.
2018 Jun; 67(6):669-678. doi:
10.5650/jos.ess17257. [PMID: 29760331] - Bhaskaragoud G, Geetha V, Sharanappa T, Mohan Kumar A S, Hema Kumar C, Suresh Kumar G. Hypolipidemic and Antioxidant Properties of Oryzanol Concentrate in Reducing Diabetic Nephropathy via SREBP1 Downregulation Rather than β-Oxidation.
Molecular nutrition & food research.
2018 04; 62(8):e1700511. doi:
10.1002/mnfr.201700511. [PMID: 29469229] - Warangkana Pornputtapitak, Jaturavit Pantakitcharoenkul, Ratchada Panpakdee, Veerawat Teeranachaideekul, Nuttanan Sinchaipanid. Development of γ-Oryzanol Rich Extract from Leum Pua Glutinous Rice Bran Loaded Nanostructured Lipid Carriers for Topical Delivery.
Journal of oleo science.
2018 Feb; 67(2):125-133. doi:
10.5650/jos.ess17113. [PMID: 29367479] - Fabiane Valentini Francisqueti, Artur Junio Togneri Ferron, Fabiana Kurokawa Hasimoto, Pedro Henrique Rizzi Alves, Jéssica Leite Garcia, Klinsmann Carolo Dos Santos, Fernando Moreto, Vanessa Dos Santos Silva, Ana Lúcia A Ferreira, Igor Otávio Minatel, Camila Renata Corrêa. Gamma Oryzanol Treats Obesity-Induced Kidney Injuries by Modulating the Adiponectin Receptor 2/PPAR-α Axis.
Oxidative medicine and cellular longevity.
2018; 2018(?):1278392. doi:
10.1155/2018/1278392. [PMID: 30271526] - W Rungratanawanich, G Abate, M M Serafini, M Guarienti, M Catanzaro, M Marziano, M Memo, C Lanni, D Uberti. Characterization of the Antioxidant Effects of γ-Oryzanol: Involvement of the Nrf2 Pathway.
Oxidative medicine and cellular longevity.
2018; 2018(?):2987249. doi:
10.1155/2018/2987249. [PMID: 29725495] - Fabiane Valentini Francisqueti, Igor Otávio Minatel, Artur Junio Togneri Ferron, Silméia Garcia Zanati Bazan, Vanessa Dos Santos Silva, Jéssica Leite Garcia, Dijon Henrique Salomé de Campos, Ana Lúcia Ferreira, Fernando Moreto, Antonio Carlos Cicogna, Camila Renata Corrêa. Effect of Gamma-Oryzanol as Therapeutic Agent to Prevent Cardiorenal Metabolic Syndrome in Animals Submitted to High Sugar-Fat Diet.
Nutrients.
2017 Nov; 9(12):. doi:
10.3390/nu9121299. [PMID: 29186059] - Long Wang, Qinlu Lin, Tao Yang, Ying Liang, Ying Nie, Yi Luo, Junjun Shen, Xiangjin Fu, Yiping Tang, Feijun Luo. Oryzanol Modifies High Fat Diet-Induced Obesity, Liver Gene Expression Profile, and Inflammation Response in Mice.
Journal of agricultural and food chemistry.
2017 Sep; 65(38):8374-8385. doi:
10.1021/acs.jafc.7b03230. [PMID: 28853872] - Soon Young Shin, Heon-Woong Kim, Hwan-Hee Jang, Yu-Jin Hwang, Jeong-Sook Choe, Yoongho Lim, Jung-Bong Kim, Young Han Lee. γ-Oryzanol-Rich Black Rice Bran Extract Enhances the Innate Immune Response.
Journal of medicinal food.
2017 Sep; 20(9):855-863. doi:
10.1089/jmf.2017.3966. [PMID: 28686509] - Xinmei Jin, Lijun Ding, Depeng Xia, Peifang Chen. [Effects of acupoint catgut embedding combined with auricular point pressure on menopausal syndrome of liver-kidney deficiency type and estradiol].
Zhongguo zhen jiu = Chinese acupuncture & moxibustion.
2017 Aug; 37(8):836-839. doi:
10.13703/j.0255-2930.2017.08.010. [PMID: 29231343] - Kelly Cristina Massarolo, Taiana Denardi de Souza, Carolina Carvalho Collazzo, Eliana Badiale Furlong, Leonor Almeida de Souza Soares. The impact of Rhizopus oryzae cultivation on rice bran: Gamma-oryzanol recovery and its antioxidant properties.
Food chemistry.
2017 Aug; 228(?):43-49. doi:
10.1016/j.foodchem.2017.01.127. [PMID: 28317745] - Takumi Ogawa, Koji Kashima, Yoshikazu Yuki, Mio Mejima, Shiho Kurokawa, Masaharu Kuroda, Atsushi Okazawa, Hiroshi Kiyono, Daisaku Ohta. Seed Metabolome Analysis of a Transgenic Rice Line Expressing Cholera Toxin B-subunit.
Scientific reports.
2017 07; 7(1):5196. doi:
10.1038/s41598-017-04701-w. [PMID: 28701756] - Saman Heydari, Saeed Ghanbarzadeh, Behzad Anoush, Mohammadreza Ranjkesh, Yousef Javadzadeh, Maryam Kouhsoltani, Hamed Hamishehkar. Nanoethosomal formulation of gammaoryzanol for skin-aging protection and wrinkle improvement: a histopathological study.
Drug development and industrial pharmacy.
2017 Jul; 43(7):1154-1162. doi:
10.1080/03639045.2017.1300169. [PMID: 28277843] - Hoa Thi Truong, Phuong Duc Luu, Kiyoshi Imamura, Takeo Matsubara, Hideki Takahashi, Norimichi Takenaka, Luu Van Boi, Yasuaki Maeda. Binary Solvent Extraction of Tocols, γ-Oryzanol, and Ferulic Acid from Rice Bran Using Alkaline Treatment Combined with Ultrasonication.
Journal of agricultural and food chemistry.
2017 Jun; 65(24):4897-4904. doi:
10.1021/acs.jafc.7b00055. [PMID: 28541677] - Sukanya Mingyai, Aikkarach Kettawan, Khongsak Srikaeo, Riantong Singanusong. Physicochemical and Antioxidant Properties of Rice Bran Oils Produced from Colored Rice Using Different Extraction Methods.
Journal of oleo science.
2017 Jun; 66(6):565-572. doi:
10.5650/jos.ess17014. [PMID: 28515384] - Felix Aladedunye, Roman Przybylski, Bertrand Matthaus. Performance of antioxidative compounds under frying conditions: A review.
Critical reviews in food science and nutrition.
2017 May; 57(8):1539-1561. doi:
10.1080/10408398.2013.777686. [PMID: 25607749] - Cristina Perez-Ternero, Carmen Claro, Juan Parrado, Maria Dolores Herrera, Maria Alvarez de Sotomayor. Rice bran enzymatic extract reduces atherosclerotic plaque development and steatosis in high-fat fed ApoE-/- mice.
Nutrition (Burbank, Los Angeles County, Calif.).
2017 May; 37(?):22-29. doi:
10.1016/j.nut.2016.12.005. [PMID: 28359358] - Tawanda Muzhingi, Natalia Palacios-Rojas, Alejandra Miranda, Maria L Cabrera, Kyung-J Yeum, Guangwen Tang. Genetic variation of carotenoids, vitamin E and phenolic compounds in Provitamin A biofortified maize.
Journal of the science of food and agriculture.
2017 Feb; 97(3):793-801. doi:
10.1002/jsfa.7798. [PMID: 27173638] - C Perez-Ternero, M D Herrera, U Laufs, M Alvarez de Sotomayor, C Werner. Food supplementation with rice bran enzymatic extract prevents vascular apoptosis and atherogenesis in ApoE-/- mice.
European journal of nutrition.
2017 Feb; 56(1):225-236. doi:
10.1007/s00394-015-1074-z. [PMID: 26476632] - Sujitra Thaithet, Supaporn Kradtap Hartwell, Somchai Lapanantnoppakhun. Sequential Injection Chromatography with an Ultra-short Monolithic Column for the Low-Pressure Separation of α-Tocopherol and γ-Oryzanol in Vegetable Oils and Nutrition Supplements.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2017; 33(3):313-319. doi:
10.2116/analsci.33.313. [PMID: 28302972] - Yogita P Pal, Amit P Pratap. Rice Bran Oil: A Versatile Source for Edible and Industrial Applications.
Journal of oleo science.
2017; 66(6):551-556. doi:
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Food & function.
2016 Dec; 7(12):4816-4822. doi:
10.1039/c6fo01552b. [PMID: 27878202] - Phumon Sookwong, Panawan Suttiarporn, Pittayaporn Boontakham, Pattawat Seekhow, Sutee Wangtueai, Sugunya Mahatheeranont. Simultaneous quantification of vitamin E, γ-oryzanols and xanthophylls from rice bran essences extracted by supercritical CO2.
Food chemistry.
2016 Nov; 211(?):140-7. doi:
10.1016/j.foodchem.2016.05.001. [PMID: 27283617] - Y Poorna Chandra Rao, D Sugasini, B R Lokesh. Dietary gamma oryzanol plays a significant role in the anti-inflammatory activity of rice bran oil by decreasing pro-inflammatory mediators secreted by peritoneal macrophages of rats.
Biochemical and biophysical research communications.
2016 Oct; 479(4):747-752. doi:
10.1016/j.bbrc.2016.09.140. [PMID: 27693794] - Xiao-Wei Chen, Ya-Jun Chen, Jin-Mei Wang, Jian Guo, Shou-Wei Yin, Xiao-Quan Yang. Phytosterol structured algae oil nanoemulsions and powders: improving antioxidant and flavor properties.
Food & function.
2016 Sep; 7(9):3694-702. doi:
10.1039/c6fo00449k. [PMID: 27501908] - Mustapha Umar Imam, Maznah Ismail, Der Jiun Ooi, Nur Hanisah Azmi, Nadarajan Sarega, Kim Wei Chan, Muhammad Iqbal Bhanger. Are bioactive-rich fractions functionally richer?.
Critical reviews in biotechnology.
2016 Aug; 36(4):585-93. doi:
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Biochemical and biophysical research communications.
2016 07; 476(2):82-9. doi:
10.1016/j.bbrc.2016.05.053. [PMID: 27179780] - Igor Otavio Minatel, Yoon-Mi Lee, Haelim Yoon, Young Yoon, Sang-Ik Han, Camila Renata Correa, Denise Fecchio, Kyung-Jin Yeum. Antiadipogenic Activity of γ-Oryzanol and Its Stability in Pigmented Rice.
Journal of medicinal food.
2016 Jul; 19(7):710-5. doi:
10.1089/jmf.2015.3647. [PMID: 27309274] - Yu-Ping Huang, Hsi-Mei Lai. Bioactive compounds and antioxidative activity of colored rice bran.
Journal of food and drug analysis.
2016 07; 24(3):564-574. doi:
10.1016/j.jfda.2016.01.004. [PMID: 28911562] - Dan Zhu, Antoni Sánchez-Ferrer, Laura Nyström. Antioxidant Activity of Individual Steryl Ferulates from Various Cereal Grain Sources.
Journal of natural products.
2016 Feb; 79(2):308-16. doi:
10.1021/acs.jnatprod.5b00880. [PMID: 26790041] - Stephanie Hagl, Dirk Berressem, Rehka Grewal, Nadine Sus, Jan Frank, Gunter P Eckert. Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice.
Nutritional neuroscience.
2016; 19(1):1-10. doi:
10.1179/1476830515y.0000000040. [PMID: 26241203] - Stífani Machado Araujo, Mariane Trindade de Paula, Marcia Rósula Poetini, Luana Meichtry, Vandreza Cardoso Bortolotto, Micheli Stefani Zarzecki, Cristiano Ricardo Jesse, Marina Prigol. Effectiveness of γ-oryzanol in reducing neuromotor deficits, dopamine depletion and oxidative stress in a Drosophila melanogaster model of Parkinson's disease induced by rotenone.
Neurotoxicology.
2015 Dec; 51(?):96-105. doi:
10.1016/j.neuro.2015.09.003. [PMID: 26366809] - Tossaton Charoonratana, Thanapat Songsak, Apirak Sakunpak, Pathamaporn Pathompak, Laksana Charoenchai. [Using liquid chromatography-mass spectrometry based metabolomics to discriminate between cold pressed rice bran oils produced from two different cultivars of Oryza sativa L. ssp. indica in Thailand].
Se pu = Chinese journal of chromatography.
2015 Sep; 33(9):966-73. doi:
10.3724/sp.j.1123.2015.04006. [PMID: 26753285] - Nam Ho Kim, Jieun Kwak, Ji Yeon Baik, Mi-Ra Yoon, Jeom-Sig Lee, Sung Won Yoon, In-Hwan Kim. Changes in lipid substances in rice during grain development.
Phytochemistry.
2015 Aug; 116(?):170-179. doi:
10.1016/j.phytochem.2015.05.004. [PMID: 26021733] - Pitchaporn Wanyo, Niwat Kaewseejan, Naret Meeso, Sirithon Siriamornpun. Marigold flower-powder exhibits significant potential to inhibit lipid oxidation in rice bran tea.
Food & function.
2015 Jun; 6(6):1808-17. doi:
10.1039/c5fo00228a. [PMID: 25927551] - Ou Wang, Jia Liu, Qian Cheng, Xiaoxuan Guo, Yong Wang, Liang Zhao, Feng Zhou, Baoping Ji. Effects of ferulic acid and γ-oryzanol on high-fat and high-fructose diet-induced metabolic syndrome in rats.
PloS one.
2015; 10(2):e0118135. doi:
10.1371/journal.pone.0118135. [PMID: 25646799] - Kazuo Mukai, Eri Ishikawa, Takumi Abe, Aya Ouchi, Shin-Ichi Nagaoka, Kazumasa Murata, Teruo Miyazawa, Kiyotaka Nakagawa. Kinetic study of the quenching reaction of singlet oxygen by seven rice bran extracts in ethanol solution. Development of a singlet oxygen absorption capacity (SOAC) assay method.
Bioscience, biotechnology, and biochemistry.
2015; 79(12):2063-72. doi:
10.1080/09168451.2015.1069701. [PMID: 26222314] - Daichi Ijiri, Tsutomu Nojima, Mana Kawaguchi, Yoko Yamauchi, Yoshikazu Fujita, Satoru Ijiri, Akira Ohtsuka. Effects of feeding outer bran fraction of rice on lipid accumulation and fecal excretion in rats.
Bioscience, biotechnology, and biochemistry.
2015; 79(8):1337-41. doi:
10.1080/09168451.2015.1032883. [PMID: 25867004] - Norsharina Ismail, Maznah Ismail, Mustapha Umar Imam, Nur Hanisah Azmi, Siti Farhana Fathy, Jhi Biau Foo, Muhammad Firdaus Abu Bakar. Mechanistic basis for protection of differentiated SH-SY5Y cells by oryzanol-rich fraction against hydrogen peroxide-induced neurotoxicity.
BMC complementary and alternative medicine.
2014 Dec; 14(?):467. doi:
10.1186/1472-6882-14-467. [PMID: 25475556] - Igor Otavio Minatel, Sang-Ik Han, Giancarlo Aldini, Mara Colzani, Nirupa R Matthan, Camila Renata Correa, Denise Fecchio, Kyung-Jin Yeum. Fat-soluble bioactive components in colored rice varieties.
Journal of medicinal food.
2014 Oct; 17(10):1134-41. doi:
10.1089/jmf.2014.3146. [PMID: 25162990] - Yu-Xin Wang, Yang Li, An-Min Sun, Feng-Jiao Wang, Guo-Ping Yu. Hypolipidemic and antioxidative effects of aqueous enzymatic extract from rice bran in rats fed a high-fat and -cholesterol diet.
Nutrients.
2014 Sep; 6(9):3696-710. doi:
10.3390/nu6093696. [PMID: 25230211] - Byungrok Min, Anna McClung, Ming-Hsuan Chen. Effects of hydrothermal processes on antioxidants in brown, purple and red bran whole grain rice (Oryza sativa L.).
Food chemistry.
2014 Sep; 159(?):106-15. doi:
10.1016/j.foodchem.2014.02.164. [PMID: 24767032] - Sakuntala Uttama, Arunpomrn Itharat, Rujiluk Rattarom, Sunita Makchuchit, Sumalee Panthong, Intouch Sakpakdeejaroen. Biological activities and chemical content of Sung Yod rice bran oil extracted by expression and soxhlet extraction methods.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet.
2014 Aug; 97 Suppl 8(?):S125-32. doi:
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Indian journal of biochemistry & biophysics.
2014 Feb; 51(1):75-80. doi:
". [PMID: 24791420] - Ratana Banjerdpongchai, Benjawan Wudtiwai, Korawan Sringarm. Cytotoxic and apoptotic-inducing effects of purple rice extracts and chemotherapeutic drugs on human cancer cell lines.
Asian Pacific journal of cancer prevention : APJCP.
2014 Jan; 14(11):6541-8. doi:
10.7314/apjcp.2013.14.11.6541. [PMID: 24377565] - Jae-Suk Choi, Min-Hee Jeon, Woi-Sook Moon, Jin-Nam Moon, Eun Jin Cheon, Joo-Wan Kim, Sung Kyu Jung, Yi-Hwa Ji, Sang Wook Son, Mi-Ryung Kim. In vivo hair growth-promoting effect of rice bran extract prepared by supercritical carbon dioxide fluid.
Biological & pharmaceutical bulletin.
2014; 37(1):44-53. doi:
10.1248/bpb.b13-00528. [PMID: 24389480]