Flazin (BioDeep_00000618469)

Main id: BioDeep_00000017455

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


1-[5-(Hydroxymethyl)-2-furanyl]-9H-pyrido[3,4-b]indole-3-carboxylic acid, 9CI

化学式: C17H12N2O4 (308.0797032)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C2C(=C1)C3=CC(=NC(=C3N2)C4=CC=C(O4)CO)C(=O)O
InChI: InChI=1S/C17H12N2O4/c20-8-9-5-6-14(23-9)16-15-11(7-13(19-16)17(21)22)10-3-1-2-4-12(10)18-15/h1-7,18,20H,8H2,(H,21,22)

描述信息

同义名列表

10 个代谢物同义名

9H-Pyrido(3,4-b)indole-3-carboxylic acid, 1-(5-(hydroxymethyl)-2-furanyl)-; 1-[5-(hydroxymethyl)furan-2-yl]-9H-pyrido[5,4-b]indole-3-carboxylic acid; 1-[5-(hydroxymethyl)-2-furyl]-9H-pyrido[5,4-b]indole-3-carboxylic acid; 1-[5-(Hydroxymethyl)-2-furyl]-9H-beta-carboline-3-carboxylic acid; 1-(5-methylol-2-furyl)-9H-$b-carboline-3-carboxylic acid; 100041-05-2; flazine; Flazin; 1-[5-(Hydroxymethyl)-2-furanyl]-9H-pyrido[3,4-b]indole-3-carboxylic acid, 9CI; 1-[5-(hydroxymethyl)furan-2-yl]-9H-pyrido[3,4-b]indole-3-carboxylic acid



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

22 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Xunzhi Wu, Zhen Chen, Yue Wu, Yifan Chen, Jiaping Jia, Nianqiu Shen, Hitoshi Chiba, Shu-Ping Hui. Flazin as a Lipid Droplet Regulator against Lipid Disorders. Nutrients. 2022 Apr; 14(7):. doi: 10.3390/nu14071501. [PMID: 35406114]
  • Ying Kong, Li-Hua Wang, Lei Liu, Li-Hua Zheng, Yong-Li Bao, Xiu-Xian Liu, Shu-Yue Wang, Zhen-Bo Song. Immunomodulatory effects of flazin from Crassostrea sikamea on splenic lymphocytes of Sprague-Dawley rats. Chinese journal of natural medicines. 2021 Nov; 19(11):836-843. doi: 10.1016/s1875-5364(21)60119-x. [PMID: 34844722]
  • Su Hui Seong, Hyun Ah Jung, Jae Sue Choi. Discovery of Flazin, an Alkaloid Isolated from Cherry Tomato Juice, As a Novel Non-Enzymatic Protein Glycation Inhibitor via in Vitro and in Silico Studies. Journal of agricultural and food chemistry. 2021 Mar; 69(12):3647-3657. doi: 10.1021/acs.jafc.0c07486. [PMID: 33739098]
  • Huipin Li, Mouming Zhao, Guowan Su, Lianzhu Lin, Yong Wang. Effect of Soy Sauce on Serum Uric Acid Levels in Hyperuricemic Rats and Identification of Flazin as a Potent Xanthine Oxidase Inhibitor. Journal of agricultural and food chemistry. 2016 Jun; 64(23):4725-34. doi: 10.1021/acs.jafc.6b01094. [PMID: 27181598]
  • Jian-Guo Tang, Yun-Hua Wang, Rui-Rui Wang, Ze-Jun Dong, Liu-Meng Yang, Yong-Tang Zheng, Ji-Kai Liu. Synthesis of analogues of flazin, in particular, flazinamide, as promising anti-HIV agents. Chemistry & biodiversity. 2008 Mar; 5(3):447-60. doi: 10.1002/cbdv.200890044. [PMID: 18357553]
  • Guo-Fang Lai, Shi-De Luo, Jian-Xin Cao, Yi-Fen Wang. [Studies on chemical constituents from roots of Mirabilis jalapa]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2008 Jan; 33(1):42-6. doi: . [PMID: 18338618]