Robenz (BioDeep_00000617208)
代谢物信息卡片
化学式: C15H13Cl2N5 (333.0547958)
中文名称: 盐酸氯苯胍
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=CC=C1C=NNC(=NN=CC2=CC=C(C=C2)Cl)N)Cl
InChI: InChI=1S/C15H13Cl2N5/c16-13-5-1-11(2-6-13)9-19-21-15(18)22-20-10-12-3-7-14(17)8-4-12/h1-10H,(H3,18,21,22)/b19-9-,20-10+
描述信息
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
同义名列表
19 个代谢物同义名
3-[(E)-[(4-chlorophenyl)methylidene]amino]-1-[(Z)-[(4-chlorophenyl)methylidene]amino]guanidine; Bis[(4-chlorophenyl)methylene]carbonimidic dihydrazide, 9ci; Bis((4-chlorophenyl)methylene)-carbonimidic dihydrazide; Bis[(4-chlorophenyl)methylene]-carbonimidic dihydrazide; 1,3-Bis[(p-chlorobenzylidene)amino]guanidine, 8ci; 1,3-Bis((p-chlorobenzylidene)amino)-guanidine; 1,3-Bis((p-chlorobenzylidene)amino)guanidine; Robenidine hydrochloride; Robenidine [inn:ban]; Khimkoktside; Khimkoktsid; Robenzidine; Robenzidene; Chimcoccide; Robenidinum; Robenidina; Robenidine; Khimcoccid; Robenz
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Hang Thi Nguyen, Henrietta Venter, Tania Veltman, Ruth Williams, Lisa Anne O'Donovan, Cecilia C Russell, Adam McCluskey, Stephen W Page, Abiodun David Ogunniyi, Darren J Trott. In vitro synergistic activity of NCL195 in combination with colistin against Gram-negative bacterial pathogens.
International journal of antimicrobial agents.
2021 May; 57(5):106323. doi:
10.1016/j.ijantimicag.2021.106323. [PMID: 33746046] - Abiodun D Ogunniyi, Manouchehr Khazandi, Andrew J Stevens, Sarah K Sims, Stephen W Page, Sanjay Garg, Henrietta Venter, Andrew Powell, Karen White, Kiro R Petrovski, Geraldine Laven-Law, Eliane G Tótoli, Hérida R Salgado, Hongfei Pi, Geoffrey W Coombs, Dean L Shinabarger, John D Turnidge, James C Paton, Adam McCluskey, Darren J Trott. Evaluation of robenidine analog NCL195 as a novel broad-spectrum antibacterial agent.
PloS one.
2017; 12(9):e0183457. doi:
10.1371/journal.pone.0183457. [PMID: 28873428] - Chun Liu, Sheng-Jie Wang, Qian Zhang, Yi-Xiang Shao. Influence of three coccidiostats on the pharmacokinetics of florfenicol in rabbits.
Experimental animals.
2015; 64(1):73-9. doi:
10.1538/expanim.14-0064. [PMID: 25319758] - Paweł Nosal, Dorota Kowalska, Paweł Bielański, Jerzy Kowal, Sławomir Kornaś. Herbal formulations as feed additives in the course of rabbit subclinical coccidiosis.
Annals of parasitology.
2014; 60(1):65-9. doi:
NULL. [PMID: 24930248] - Adnane Remmal, Sanaa Achahbar, Latifa Bouddine, Najat Chami, Fouzia Chami. In vitro destruction of Eimeria oocysts by essential oils.
Veterinary parasitology.
2011 Dec; 182(2-4):121-6. doi:
10.1016/j.vetpar.2011.06.002. [PMID: 21726944] - B L Pan, Y F Zhang, X Suo, Y Xue. Effect of subcutaneously administered diclazuril on the output of Eimeria species oocysts by experimentally infected rabbits.
The Veterinary record.
2008 Feb; 162(5):153-5. doi:
10.1136/vr.162.5.153. [PMID: 18245747] - R Brun, C Burri, C W Gichuki. The story of CGP 40 215: studies on its efficacy and pharmacokinetics in African green monkey infected with Trypanosoma brucei rhodesiense.
Tropical medicine & international health : TM & IH.
2001 May; 6(5):362-8. doi:
10.1046/j.1365-3156.2001.00728.x. [PMID: 11348531] - H D Chapman, A B Hacker. The effects of shuttle programs upon the growth of broilers and the development of immunity to eimeria species.
Poultry science.
1993 Apr; 72(4):658-63. doi:
10.3382/ps.0720658. [PMID: 8479951] - J E Peeters, R Geeroms. Efficacy of diclazuril against robenidine resistant Eimeria magna in rabbits.
The Veterinary record.
1989 Jun; 124(22):589-90. doi:
10.1136/vr.124.22.589. [PMID: 2773198] - L P Joyner, J Catchpole, S Berrett. Eimeria stiedai in rabbits: the demonstration of responses to chemotherapy.
Research in veterinary science.
1983 Jan; 34(1):64-7. doi:
10.1016/s0034-5288(18)32285-9. [PMID: 6132429] - J E Tulliez, E F Durand, G F Bories. Metabolic fate and pharmacokinetics of tissue residues of the anticoccidial drug robenidine in the rabbit. Incidence of coprophagy on its bioavailability.
Journal of agricultural and food chemistry.
1982 Nov; 30(6):1071-5. doi:
10.1021/jf00114a016. [PMID: 6890962] - J E Peeters, P Halen. Robenidine treatment of rabbits naturally infected with coccidia.
Laboratory animals.
1980 Jan; 14(1):53-4. doi:
10.1258/002367780780943024. [PMID: 7359888] - L R McDougald, R B Galloway. Eimeria tenella: inhibition of development in cell culture by serum from chickens fed anticoccidial drugs.
Zeitschrift fur Parasitenkunde (Berlin, Germany).
1977 Dec; 54(1):95-100. doi:
10.1007/bf00380642. [PMID: 602371] - J E Smith, N R Pasarela, J C Wyckoff. Polarographic determination of robenidine residues in chicken tissues, eggs, litter, soil, and plant tissue.
Journal - Association of Official Analytical Chemists.
1977 Nov; 60(6):1310-7. doi:
NULL. [PMID: 924934] - E H Lee, M A Fernando. Drug resistance in coccidia: a robenidine-resistant strain of eimeria tenella.
Canadian journal of comparative medicine : Revue canadienne de medecine comparee.
1977 Oct; 41(4):466-70. doi:
NULL. [PMID: 922562] - H D Chapman. Eimeria tenella: experimental studies on the development of resistance to robenidine.
Parasitology.
1976 Dec; 73(3):265-73. doi:
10.1017/s0031182000046953. [PMID: 1012746] - L R McDougald, R B Galloway. Anticoccidial drugs: effects on infectivity and survival intracellularly of Eimeria tenella sporozoites.
Experimental parasitology.
1976 Dec; 40(3):314-9. doi:
10.1016/0014-4894(76)90098-9. [PMID: 976419]