Sotret (BioDeep_00000616338)
Main id: BioDeep_00000014553
代谢物信息卡片
13-cis-retinoic acid, Isotretinoin
化学式: C20H28O2 (300.2089)
中文名称: 13-顺-视黄酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
InChI: InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14-
描述信息
D - Dermatologicals > D10 - Anti-acne preparations > D10A - Anti-acne preparations for topical use > D10AD - Retinoids for topical use in acne
D - Dermatologicals > D10 - Anti-acne preparations > D10B - Anti-acne preparations for systemic use > D10BA - Retinoids for treatment of acne
C274 - Antineoplastic Agent > C2122 - Cell Differentiating Agent > C1934 - Differentiation Inducer
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C804 - Retinoic Acid Agent
C308 - Immunotherapeutic Agent > C129820 - Antineoplastic Immunomodulating Agent
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
D009676 - Noxae > D013723 - Teratogens
D003879 - Dermatologic Agents
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:6067
- KEGG: C07058
- KEGGdrug: D00348
- PubChem: 5282379
- Metlin: METLIN870
- DrugBank: DB00982
- ChEMBL: CHEMBL547
- MeSH: Isotretinoin
- CAS: 4759-48-2
- PubChem: 9270
- LipidMAPS: LMPR01090021
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Madiha Sajid, Sadaf Ahmed Asim, Tayyaba Iqbal, Sadia Bhatti, Ayesha Zahir, Sania Imtiaz. Isotretinoin's Effect on Fasting Lipid Profile in Acne Patients.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP.
2024 May; 34(5):518-521. doi:
10.29271/jcpsp.2024.05.518. [PMID: 38720209] - Yiting Li, Yibin Zeng, Zile Chen, Shu Nie, Zhouwei Wu. The efficiency and safety of low-dosage isotretinoin therapy for Chinese acne vulgaris patients.
Journal of cosmetic dermatology.
2024 Mar; 23(3):926-930. doi:
10.1111/jocd.16073. [PMID: 37934937] - Nubar Nuriyeva, Emir Enis Yurdgulu, Abdulmecit Albayrak, Huseyn Aliyev, Kubra Aliyeva, Beyzagul Erkayman, Yasin Bayir. Evaluation of the protective effects of curcumin-rich turmeric (Curcuma longa) extract against isotretinoin-induced liver damage in rats.
Toxicology mechanisms and methods.
2024 Feb; 34(2):122-129. doi:
10.1080/15376516.2023.2260454. [PMID: 37771095] - Ahmet Alp Bilgic, Huri Sabur, Mutlu Acar, Filiz Canpolat. Effects of lipid-containing eye drops on the ocular surface and in vivo confocal microscopy findings in patients using systemic isotretinoin.
Cutaneous and ocular toxicology.
2023 Mar; 42(1):25-31. doi:
10.1080/15569527.2023.2166523. [PMID: 36635986] - D Morgado-Carrasco, J Gil-Lianes, E Jourdain, J Piquero-Casals. Oral Supplementation and Systemic Drugs for Skin Aging: A Narrative Review.
Actas dermo-sifiliograficas.
2023 Feb; 114(2):114-124. doi:
10.1016/j.ad.2022.09.014. [PMID: 36206809] - Mohammad Salem Hareedy, Khaled Mohamed Tawfik. Systemic isotretinoin has an impact on hemoglobin, ferritin, urea, ceruloplasmin, albumin, uric acid levels, and neutrophil to lymphocyte ratio in acne patients.
Journal of cosmetic dermatology.
2022 Nov; 21(11):6191-6198. doi:
10.1111/jocd.15199. [PMID: 35770307] - Ge-Ge Gong, Jie Zheng, Sha Li, Ya-Li Bai, Yu-Qi Feng. Triple chemical derivatization strategy assisted liquid chromatography-mass spectrometry for determination of retinoic acids in human serum.
Talanta.
2022 Aug; 245(?):123474. doi:
10.1016/j.talanta.2022.123474. [PMID: 35462137] - Agnieszka Kaźmierska, Izabela Bolesławska, Adriana Polańska, Aleksandra Dańczak-Pazdrowska, Paweł Jagielski, Sławomira Drzymała-Czyż, Zygmunt Adamski, Juliusz Przysławski. Effect of Evening Primrose Oil Supplementation on Selected Parameters of Skin Condition in a Group of Patients Treated with Isotretinoin-A Randomized Double-Blind Trial.
Nutrients.
2022 Jul; 14(14):. doi:
10.3390/nu14142980. [PMID: 35889936] - P R Criado, M Ianhez, P S Rocha, H A Miot. Pityriasis rubra pilaris (type I) following ChAdOx1 COVID-19 vaccine: A report of two cases with successful treatment with oral isotretinoin.
Journal of the European Academy of Dermatology and Venereology : JEADV.
2022 07; 36(7):e508-e510. doi:
10.1111/jdv.18055. [PMID: 35278239] - Aprajita S Yadav, Faith Stevison, Mika Kosaka, Susan Wong, Jane R Kenny, John K Amory, Nina Isoherranen. Isotretinoin and its Metabolites Alter mRNA of Multiple Enzyme and Transporter Genes In Vitro, but Downregulation of Organic Anion Transporting Polypeptide Does Not Translate to the Clinic.
Drug metabolism and disposition: the biological fate of chemicals.
2022 Jul; 50(7):1042-1052. doi:
10.1124/dmd.122.000882. [PMID: 35545255] - Agnieszka Kaźmierska, Izabela Bolesławska, Paweł Jagielski, Adriana Polańska, Aleksandra Dańczak-Pazdrowska, Grzegorz Kosewski, Zygmunt Adamski, Juliusz Przysławski. Effect of Evening Primrose Oil Supplementation on Biochemical Parameters and Nutrition of Patients Treated with Isotretinoin for Acne Vulgaris: A Randomized Double-Blind Trial.
Nutrients.
2022 Mar; 14(7):. doi:
10.3390/nu14071342. [PMID: 35405955] - Nalan Sarac, Gunseli S Pancar, Sule Ozdemir, Serra Atilla. A retrospective evaluation of laboratory parameters and hyperuricemia in patients with acne vulgaris under systemic isotretinoin treatment.
The Journal of dermatological treatment.
2022 Mar; 33(2):1063-1066. doi:
10.1080/09546634.2020.1800575. [PMID: 32705916] - Marc Hoemberg, Ruth Schwenzfeur, Frank Berthold, Thorsten Simon, Barbara Hero. Hypercalcemia is a frequent side effect of 13-cis-retinoic acid treatment in patients with high-risk neuroblastoma.
Pediatric blood & cancer.
2022 02; 69(2):e29374. doi:
10.1002/pbc.29374. [PMID: 34569150] - A Gan, A Therianou. How safe and effective is prescribing oral isotretinoin to treat acne in patients on renal dialysis? A systematic review.
Clinical and experimental dermatology.
2022 Jan; 47(1):16-23. doi:
10.1111/ced.14886. [PMID: 34388284] - Ying-Xuan Huang, Yu-Ying Chao, Yi-Hui Lin, Jing-Ru Liou, Hai-Chi Chan, Yen-Ling Chen. Determination of 13-cis-Retinoic Acid and Its Metabolites in Plasma by Micellar Electrokinetic Chromatography Using Cyclodextrin-Assisted Sweeping for Sample Preconcentration.
Molecules (Basel, Switzerland).
2021 Sep; 26(19):. doi:
10.3390/molecules26195865. [PMID: 34641409] - Nurcan Metin, Çağrı Turan. Increases in uric acid and monocyte-high-density lipoprotein ratio as possible atherosclerotic indicators in acne patients using isotretinoin.
Journal of cosmetic dermatology.
2021 Sep; 20(9):2945-2949. doi:
10.1111/jocd.13931. [PMID: 33387386] - Gajanand Sharma, Yukhti Yachha, Kanika Thakur, Akanksha Mahajan, Gurjeet Kaur, Bhupinder Singh, Kaisar Raza, O P Katare. Co-delivery of isotretinoin and clindamycin by phospholipid-based mixed micellar system confers synergistic effect for treatment of acne vulgaris.
Expert opinion on drug delivery.
2021 09; 18(9):1291-1308. doi:
10.1080/17425247.2021.1919618. [PMID: 33870824] - Ayman Abdelmaksoud, Anant Patil, Recep Dursun, Selami Aykut Temiz, Erhan Ayhan, Mohamad Goldust, Michelangelo Vestita. Could isotretinoin be a protective agent against COVID-19?: A dermatologist perspective.
Journal of cosmetic dermatology.
2021 Aug; 20(8):2394-2395. doi:
10.1111/jocd.14239. [PMID: 34008285] - Mohammed Al-Haddab, Alanoud Alhuqayl, Heba Alsharif, Dana Alolyet, Rawan Altaleb. Results of Laboratory Monitoring in Patients Taking Isotretinoin for Acne.
Cutis.
2021 Jul; 108(1):43-45. doi:
10.12788/cutis.0291. [PMID: 34397358] - Lorraine L Rosamilia. Isotretinoin Meets COVID-19: Revisiting a Fragmented Paradigm.
Cutis.
2021 07; 108(1):8-12. doi:
10.12788/cutis.0299. [PMID: 34397350] - Neslihan Demirel Öğüt, Ömer Kutlu, Ece Erbağcı. Oral isotretinoin treatment in patients with acne vulgaris during the COVID-19 pandemic: A retrospective cohort study in a tertiary care hospital.
Journal of cosmetic dermatology.
2021 Jul; 20(7):1969-1974. doi:
10.1111/jocd.14168. [PMID: 33884755] - Mustafa Gundogdu, Gokturk Dere. Is systemic isotretinoin use a risk factor for coronavirus disease 2019 (COVID-19)?.
Journal of cosmetic dermatology.
2021 Jun; 20(6):1568-1570. doi:
10.1111/jocd.14044. [PMID: 33682290] - Justin Lee, Ahmed Yousaf, Samantha Jenkins, Mohammed Tamim Zaki, Cecelia Napier, Omar I Abdul-Aziz, Zachary Zinn. The positive environmental impact of virtual isotretinoin management.
Pediatric dermatology.
2021 May; 38(3):613-616. doi:
10.1111/pde.14600. [PMID: 33870555] - Madison Jones, April W Armstrong, Hilary Baldwin, Linda Stein Gold, Leon H Kircik. ARTICLE: Advances in Oral Isotretinoin Therapy.
Journal of drugs in dermatology : JDD.
2021 May; 20(5):s5-s11. doi:
10.36849/jdd.s072a. [PMID: 33938693] - Alice L Yu, Andrew L Gilman, M Fevzi Ozkaynak, Arlene Naranjo, Mitchell B Diccianni, Jacek Gan, Jacquelyn A Hank, Ayse Batova, Wendy B London, Sheena C Tenney, Malcolm Smith, Barry L Shulkin, Marguerite Parisi, Katherine K Matthay, Susan L Cohn, John M Maris, Rochelle Bagatell, Julie R Park, Paul M Sondel. Long-Term Follow-up of a Phase III Study of ch14.18 (Dinutuximab) + Cytokine Immunotherapy in Children with High-Risk Neuroblastoma: COG Study ANBL0032.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2021 04; 27(8):2179-2189. doi:
10.1158/1078-0432.ccr-20-3909. [PMID: 33504555] - Cevriye Mülkoğlu, Nermin Karaosmanoğlu. Effect of oral isotretinoin on muscle strength in patients with acne vulgaris: a prospective controlled study.
BMC pharmacology & toxicology.
2021 03; 22(1):17. doi:
10.1186/s40360-021-00483-0. [PMID: 33743831] - Aaron J Frederiks, John R Burnett, Gerald F Watts, Sujith P Kumarasinghe, Damon A Bell. The lipid profile in children prior to isotretinoin therapy: an opportunity to detect familial hypercholesterolaemia.
Pathology.
2021 Feb; 53(2):288-290. doi:
10.1016/j.pathol.2020.07.007. [PMID: 33032808] - Funda Kemeriz, Serkan Kayabaşı, Bengü Cevirgen Cemil, Ömer Hızlı. Evaluation of oral isotretinoin effects on hearing system in patients with acne vulgaris: Reversible or not?.
Dermatologic therapy.
2021 01; 34(1):e14640. doi:
10.1111/dth.14640. [PMID: 33278063] - Marianna Donnarumma, Mariateresa Nocerino, Wanda Lauro, Maria Carmela Annunziata, Claudio Marasca, Gabriella Fabbrocini. Isotretinoin in acne treatment during the coronavirus disease 2019 (COVID-19): A retrospective analysis of adherence to therapy and side effects.
Dermatologic therapy.
2021 01; 34(1):e14677. doi:
10.1111/dth.14677. [PMID: 33320409] - L S Ostlere, A S Bansal. Management of soya and peanut allergic patients taking oral isotretinoin. Comment on: 'Four-year data from use of the nut and soya testing protocol before treatment with isotretinoin and alitretinion'.
Clinical and experimental dermatology.
2020 Dec; 45(8):1070. doi:
10.1111/ced.14401. [PMID: 32725922] - Shivani Gupta, Sarika Wairkar, Lokesh Kumar Bhatt. Isotretinoin and α-tocopherol acetate-loaded solid lipid nanoparticle topical gel for the treatment of acne.
Journal of microencapsulation.
2020 Dec; 37(8):557-565. doi:
10.1080/02652048.2020.1823499. [PMID: 32924680] - James T Pathoulas, Ronda S Farah, Lori Fiessinger, Matthew Mansh. An opportunity for improvement: iPLEDGE policy changes during the coronavirus pandemic.
Dermatologic therapy.
2020 Nov; 33(6):e14411. doi:
10.1111/dth.14411. [PMID: 33052629] - Ana M Molina, Johannes C van der Mijn, Paul Christos, John Wright, Charlene Thomas, Janice P Dutcher, David M Nanus, Scott T Tagawa, Lorraine J Gudas. NCI 6896: a phase I trial of vorinostat (SAHA) and isotretinoin (13-cis retinoic acid) in the treatment of patients with advanced renal cell carcinoma.
Investigational new drugs.
2020 10; 38(5):1383-1389. doi:
10.1007/s10637-019-00880-7. [PMID: 31898184] - Ayman Abdelmaksoud, Michelangelo Vestita, Heba Saed El-Amawy, Erhan Ayhan, İsa An, Murat Öztürk, Mohamad Goldust. Systemic isotretinoin therapy in the era of COVID-19.
Dermatologic therapy.
2020 Jul; 33(4):e13482. doi:
10.1111/dth.13482. [PMID: 32358858] - Aaron Lazorwitz, Rebecca Seale, Anne Davis, Maryam Guiahi. A pilot study on the effect of isotretinoin on serum etonogestrel concentrations in contraceptive implant users.
Contraception.
2020 07; 102(1):58-60. doi:
10.1016/j.contraception.2020.04.011. [PMID: 32325076] - Pedro Rodríguez-Jiménez, Jose Luis Ramirez-Bellver, Ricardo Ruiz-Rodríguez. Alopecia areata not due by isotretinoin. A thought in COVID-19 time.
Dermatologic therapy.
2020 07; 33(4):e13451. doi:
10.1111/dth.13451. [PMID: 32323454] - Lamia Hamouda Elgarhy. Could patients taking isotretinoin therapy be immune against SARS-CoV-2?.
Dermatologic therapy.
2020 07; 33(4):e13573. doi:
10.1111/dth.13573. [PMID: 32406143] - Tsung-Yu Tsai, Han-Wen Liu, Yuan-Chen Chao, Yu-Chen Huang. Effects of isotretinoin on glucose metabolism in patients with acne: A systematic review and meta-analysis.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG.
2020 Jun; 18(6):539-545. doi:
10.1111/ddg.14108. [PMID: 32391951] - Tekden Karapınar, Mualla Polat, Güler Buğdaycı. Evaluation of subclinical atherosclerosis in Turkish patients with acne vulgaris receiving systemic isotretinoin.
Dermatologic therapy.
2020 05; 33(3):e13307. doi:
10.1111/dth.13307. [PMID: 32160377] - Seong Hoon Seo, Ju Yeon Jung, Keedon Park, Amir M Hossini, Christos C Zouboulis, Sang Eun Lee. Autophagy regulates lipid production and contributes to the sebosuppressive effect of retinoic acid in human SZ95 sebocytes.
Journal of dermatological science.
2020 May; 98(2):128-136. doi:
10.1016/j.jdermsci.2020.04.001. [PMID: 32354609] - Eleonora Rodighiero, Mariabeatrice Bertolani, Roberta Saleri, Giuseppe Pedrazzi, Torello Lotti, Claudio Feliciani, Francesca Satolli. Do acne treatments affect insulin-like growth factor-1 serum levels? A clinical and laboratory study on patients with acne vulgaris.
Dermatologic therapy.
2020 05; 33(3):e13439. doi:
10.1111/dth.13439. [PMID: 32306454] - Justin W Marson, Hilary E Baldwin. The creatine kinase conundrum: a reappraisal of the association of isotretinoin, creatine kinase, and rhabdomyolysis.
International journal of dermatology.
2020 Mar; 59(3):279-283. doi:
10.1111/ijd.14758. [PMID: 31880325] - Hyun Jung Kim, Seung Min Lee, Jong Suk Lee, Sung Yul Lee, Euy Hyun Chung, Moon Kyun Cho, Sang Hoon Lee, Jung Eun Kim. Homocysteine, folic acid, and vitamin B12 levels in patients on isotretinoin therapy for acne vulgaris: A meta-analysis.
Journal of cosmetic dermatology.
2020 Mar; 19(3):736-745. doi:
10.1111/jocd.13059. [PMID: 31276303] - Hongyang Li, Cheng Wang, Pengcheng Ma, Mengli Zhang, Hua Yang, Shengtao Yuan, Jun Wei, Lei Tao, Kun Qian, Man Xu, Lingjun Li. The retinoid derivant ECPIRM selectively exhibited anti-proliferation effects in cutaneous T-Cell lymphoma via ITK-mediated signaling pathway.
Journal of dermatological science.
2020 Mar; 97(3):208-215. doi:
10.1016/j.jdermsci.2020.01.013. [PMID: 32165081] - Cevriye Mülkoğlu, Nermin Karaosmanoğlu. Effect of Serum 25 Hydroxy Vitamin D Level on Isotretinoin-Induced Musculoskeletal Symptoms: A Cross-Sectional Study.
Scientific reports.
2020 02; 10(1):2245. doi:
10.1038/s41598-020-59167-0. [PMID: 32042004] - Gulcan Saylam Kurtipek, Gözde Ulutas Demirbas, Abdullah Demirbas, Nihal Sarı, Emre Zekey, Fatma Tuncez Akyurek, Gökhan Güngör. The effects of isotretinoin therapy on the biliary system.
Dermatologic therapy.
2020 01; 33(1):e13177. doi:
10.1111/dth.13177. [PMID: 31769896] - Nasr Y Khalil, Ibrahim A Darwish, Abdulmohsen A Al-Qahtani. Isotretinoin.
Profiles of drug substances, excipients, and related methodology.
2020; 45(?):119-157. doi:
10.1016/bs.podrm.2019.10.005. [PMID: 32164966] - John S Barbieri, Daniel B Shin, Shiyu Wang, David J Margolis, Junko Takeshita. The clinical utility of laboratory monitoring during isotretinoin therapy for acne and changes to monitoring practices over time.
Journal of the American Academy of Dermatology.
2020 Jan; 82(1):72-79. doi:
10.1016/j.jaad.2019.06.025. [PMID: 31228528] - Ivana Ilić, Nada Oršolić, Edi Rođak, Dyana Odeh, Marko Lovrić, Robert Mujkić, Marija Delaš Aždajić, Anđela Grgić, Maja Tolušić Levak, Martin Vargek, Branko Dmitrović, Tatjana Belovari. The effect of high-fat diet and 13-cis retinoic acid application on lipid profile, glycemic response and oxidative stress in female Lewis rats.
PloS one.
2020; 15(9):e0238600. doi:
10.1371/journal.pone.0238600. [PMID: 32947606] - Yusuke Marikawa, Hong-Ru Chen, Mark Menor, Youping Deng, Vernadeth B Alarcon. Exposure-based assessment of chemical teratogenicity using morphogenetic aggregates of human embryonic stem cells.
Reproductive toxicology (Elmsford, N.Y.).
2020 01; 91(?):74-91. doi:
10.1016/j.reprotox.2019.10.004. [PMID: 31711903] - Ayşe Öktem, Yıldız Hayran, Esra Arı, Başak Yalçın. Minimize the regular laboratory monitoring during the systemic isotretinoin treatment: data of 704 patients with acne vulgaris.
The Journal of dermatological treatment.
2019 Dec; 30(8):813-817. doi:
10.1080/09546634.2019.1591578. [PMID: 30836808] - Nancy S Younis, Nourah Yousef Al-Harbi. Public Understanding and Awareness of Isotretinoin Use and Safety in Al Ahsa, Eastern Saudi Arabia.
Therapeutic innovation & regulatory science.
2019 09; 53(5):618-622. doi:
10.1177/2168479018807677. [PMID: 30380941] - Emine T Alatas, Asude Kara Polat, Mehmet Kalayci, Gursoy Dogan, Aslı Akin Belli. Plasma dermcidin levels in acne patients, and the effect of isotretinoin treatment on dermcidin levels.
Dermatologic therapy.
2019 09; 32(5):e13044. doi:
10.1111/dth.13044. [PMID: 31364786] - Habibullah Aktas, Goksen Ertugrul, Muharrem Parlak, Mehmet Unal. Long-term isotretinoin use does not cause parenchymal liver change: Ultrasonographic study in 50 patients.
Dermatologic therapy.
2019 09; 32(5):e13012. doi:
10.1111/dth.13012. [PMID: 31241229] - Francesco Lacarrubba, Anna Elisa Verzì, Sebastiano Barresi, Giuseppe Micali. Multiple xanthogranulomas in an adult patient: clinical, dermoscopic, reflectance confocal microscopy and histopathological features.
BMJ case reports.
2019 Jul; 12(7):. doi:
10.1136/bcr-2019-229772. [PMID: 31266759] - Faith Stevison, Mika Kosaka, Jane R Kenny, Susan Wong, Cathryn Hogarth, John K Amory, Nina Isoherranen. Does In Vitro Cytochrome P450 Downregulation Translate to In Vivo Drug-Drug Interactions? Preclinical and Clinical Studies With 13-cis-Retinoic Acid.
Clinical and translational science.
2019 07; 12(4):350-360. doi:
10.1111/cts.12616. [PMID: 30681285] - B F Thomazini, C A Lamas, M A H Dolder. Safety of isotretinoin treatment as measured by liver parameters.
Histology and histopathology.
2019 Jul; 34(7):755-763. doi:
10.14670/hh-18-075. [PMID: 30556579] - Funda Tamer, Mehmet Eren Yuksel, Emine Avcı. Is mean platelet volume an inflammatory marker in acne patients treated with isotretinoin?.
Acta dermatovenerologica Alpina, Pannonica, et Adriatica.
2019 Jun; 28(2):65-69. doi:
10.15570/actaapa.2019.17. [PMID: 31233169] - Deniz Kulaksiz, Cavit Kart, Suleyman Guven, Kubra Akbulut, Umit Cobanoglu, Orhan Deger. Comparison of the effect of isotretionin and alitretionin on endometriotic implants and serum vascular endothelial growth factor level: an experimental study.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.
2019 Apr; 35(4):301-304. doi:
10.1080/09513590.2018.1526275. [PMID: 30600729] - Gonca Soyuduru, Esra Ösoy Adışen, İlkay Kadıoğlu Özer, A. Burhan Aksakal. The effect of isotretinoin on insulin resistance and adipocytokine levels in acne vulgaris patients.
Turkish journal of medical sciences.
2019 Feb; 49(1):238-244. doi:
10.3906/sag-1806-44. [PMID: 30761880] - Mohammed Abu El-Hamd, Moustafa A El Taieb, Hassan M Ibrahim, Sanaa S Aly. Vitamin D levels in acne vulgaris patients treated with oral isotretinoin.
Journal of cosmetic dermatology.
2019 Feb; 18(1):16-20. doi:
10.1111/jocd.12503. [PMID: 29460332] - Andrzej Wróbel, Urszula Doboszewska, Ewa Rechberger, Małgorzata Bańczerowska-Górska, Piotr Czuczwar, Ewa Poleszak, Jarosław Dudka, Piotr Wlaź, Paweł Miotła, Edyta Wlaźlak, Tomasz Rechberger. Blebbistatin, a Myosin II Inhibitor, Exerts Antidepressant-Like Activity and Suppresses Detrusor Overactivity in an Animal Model of Depression Coexisting with Overactive Bladder.
Neurotoxicity research.
2019 Jan; 35(1):196-207. doi:
10.1007/s12640-018-9948-5. [PMID: 30155683] - Andrzej Wróbel, Ewa Rechberger, Tomasz Rechberger. The influence of duloxetine on detrusor overactivity in rats with depression induced by 13-cis-retinoic acid.
International urogynecology journal.
2018 07; 29(7):987-995. doi:
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Pediatric hematology and oncology.
2018 Apr; 35(3):218-224. doi:
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Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.
2018 Feb; 34(2):107-109. doi:
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European journal of pharmacology.
2017 Oct; 812(?):216-224. doi:
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Ugeskrift for laeger.
2017 Oct; 179(40):. doi:
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Pediatrics.
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Journal of cosmetic dermatology.
2017 Sep; 16(3):348-352. doi:
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Annales de dermatologie et de venereologie.
2017 Aug; 144(8-9):508-517. doi:
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Dermatologic therapy.
2017 Jul; 30(4):. doi:
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Journal of drugs in dermatology : JDD.
2017 Jun; 16(6):557-564. doi:
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Current eye research.
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Dermatology online journal.
2017 May; 23(5):. doi:
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The Journal of dermatological treatment.
2017 Mar; 28(2):141-144. doi:
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Cutaneous and ocular toxicology.
2017 Mar; 36(1):77-84. doi:
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PLoS neglected tropical diseases.
2017 03; 11(3):e0005472. doi:
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Cutaneous and ocular toxicology.
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The Journal of dermatological treatment.
2017 Feb; 28(1):82-85. doi:
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Dermatology (Basel, Switzerland).
2017; 233(4):314-319. doi:
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European journal of pediatrics.
2016 Dec; 175(12):2005-2006. doi:
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Expert review of clinical pharmacology.
2016 Nov; 9(11):1435-1442. doi:
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Cancer chemotherapy and pharmacology.
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Journal of the American Academy of Dermatology.
2016 Aug; 75(2):323-8. doi:
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Turkish journal of medical sciences.
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JAMA dermatology.
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International journal of clinical pharmacology and therapeutics.
2015 Oct; 53(10):897-904. doi:
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Clinical and experimental dermatology.
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JPMA. The Journal of the Pakistan Medical Association.
2015 Sep; 65(9):950-3. doi:
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The journal of obstetrics and gynaecology research.
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Dermatologic therapy.
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Cutaneous and ocular toxicology.
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Medical archives (Sarajevo, Bosnia and Herzegovina).
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Gynecologic and obstetric investigation.
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