Allopurinol riboside (BioDeep_00000616064)
Main id: BioDeep_00000027585
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C10H12N4O5 (268.08076619999997)
中文名称: 别嘌呤醇核糖苷
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=NN(C2=C1C(=O)NC=N2)C3C(C(C(O3)CO)O)O
InChI: InChI=1S/C10H12N4O5/c15-2-5-6(16)7(17)10(19-5)14-8-4(1-13-14)9(18)12-3-11-8/h1,3,5-7,10,15-17H,2H2,(H,11,12,18)/t5-,6-,7-,10-/m1/s1
描述信息
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
A nucleoside analogue that is allopurinol with a beta-D-ribofuranosyl moiety at the 1-position.
Allopurinol riboside, a metabolite of allopurinol, shows potent activities against parasites.
Allopurinol riboside, a metabolite of allopurinol, shows potent activities against parasites.
同义名列表
2 个代谢物同义名
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:74074
- PubChem: 135407110
- Metlin: METLIN867
- ChEMBL: CHEMBL1688966
- ChEMBL: CHEMBL603304
- CAS: 16220-07-8
- MetaboLights: MTBLC74074
- RefMet: Allopurinol riboside
- medchemexpress: HY-101397
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jan Funke, Carsten Prasse, Christian Lütke Eversloh, Thomas A Ternes. Oxypurinol - A novel marker for wastewater contamination of the aquatic environment.
Water research.
2015 May; 74(?):257-65. doi:
10.1016/j.watres.2015.02.007. [PMID: 25753675] - Diluk R W Kannangara, Darren M Roberts, Timothy J Furlong, Garry G Graham, Kenneth M Williams, Richard O Day. Oxypurinol, allopurinol and allopurinol-1-riboside in plasma following an acute overdose of allopurinol in a patient with advanced chronic kidney disease.
British journal of clinical pharmacology.
2012 May; 73(5):828-9. doi:
10.1111/j.1365-2125.2011.04147.x. [PMID: 22098112] - J B Were, T A Shapiro. Effects of probenecid on the pharmacokinetics of allopurinol riboside.
Antimicrobial agents and chemotherapy.
1993 May; 37(5):1193-6. doi:
10.1128/aac.37.5.1193. [PMID: 8517715] - T A Shapiro, J B Were, K Danso, D J Nelson, R E Desjardins, C L Pamplin. Pharmacokinetics and metabolism of allopurinol riboside.
Clinical pharmacology and therapeutics.
1991 May; 49(5):506-14. doi:
10.1038/clpt.1991.61. [PMID: 2029827] - S Reiter, W Löffler, W Gröbner, N Zöllner. Allopurinol-1-riboside formation and HGPRT-deficiency.
Advances in experimental medicine and biology.
1986; 195 Pt A(?):447-51. doi:
10.1007/978-1-4684-5104-7_74. [PMID: 3728177] - S Reiter, W Löffler, W Gröbner, N Zöllner. Urinary oxipurinol-1-riboside excretion and allopurinol-induced oroticaciduria.
Advances in experimental medicine and biology.
1986; 195 Pt A(?):453-60. doi:
10.1007/978-1-4684-5104-7_75. [PMID: 3728178] - S Reiter, H A Simmonds, D R Webster, A R Watson. On the metabolism of allopurinol. Formation of allopurinol-1-riboside in purine nucleoside phosphorylase deficiency.
Biochemical pharmacology.
1983 Jul; 32(14):2167-74. doi:
10.1016/0006-2952(83)90222-8. [PMID: 6409116] - B Finlayson, J Burns, A Smith, L Du Bois. Effect of oxipurinol and allopurinol riboside on whewellite crystallization: in vitro and in vivo observations.
Investigative urology.
1979 Nov; 17(3):227-9. doi:
NULL. [PMID: 500322]