Ikshusterol (BioDeep_00000616034)

   


代谢物信息卡片


14-(5-ethyl-6-methylheptan-2-yl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-ene-5,9-diol

化学式: C29H50O2 (430.3811)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C[C@H](O)CC2=C[C@@H](O)[C@@]3([H])[C@]4([H])CC[C@]([H])([C@H](C)CC[C@@H](CC)C(C)C)[C@@]4(C)CC[C@]3([H])[C@@]12C
InChI: InChI=1S/C29H50O2/c1-7-20(18(2)3)9-8-19(4)23-10-11-24-27-25(13-15-29(23,24)6)28(5)14-12-22(30)16-21(28)17-26(27)31/h17-20,22-27,30-31H,7-16H2,1-6H3

描述信息

同义名列表

10 个代谢物同义名

Stigmast-5-en-3beta,7alpha-diol; 7alpha-Hydroxysitosterol; Ikshusterol; ST 29:1;O2; 14-(5-ethyl-6-methylheptan-2-yl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-ene-5,9-diol; (3beta,7alpha)-Stigmast-5-ene-3,7-diol; (-)-Stigmast-5-ene-3beta,7alpha-diol; Stigmast-5-ene-3beta,7alpha-diol; 7a-Hydroxysitosterol; Hydroxysitosterol



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Hans-Frieder Schött, Sabine Baumgartner, Constanze Husche, Alexandra Luister, Silvia Friedrichs, Charlotte M Miller, Florence O McCarthy, Jogchum Plat, Ulrich Laufs, Oliver Weingärtner, Dieter Lütjohann. Oxidation of sitosterol and transport of its 7-oxygenated products from different tissues in humans and ApoE knockout mice. The Journal of steroid biochemistry and molecular biology. 2017 05; 169(?):145-151. doi: 10.1016/j.jsbmb.2016.04.011. [PMID: 27132025]
  • Hans-Frieder Schött, Constanze Husche, Silvia Friedrichs, Charlotte M Miller, Florence O McCarthy, Ulrich Laufs, Jogchum Plat, Oliver Weingärtner, Dieter Lütjohann. 7β-Hydroxysitosterol crosses the blood-brain barrier more favored than its substrate sitosterol in ApoE-/- mice. Steroids. 2015 Jul; 99(Pt B):178-82. doi: 10.1016/j.steroids.2015.03.006. [PMID: 25795151]
  • Oliver Weingärtner, Constanze Husche, Hans F Schött, Timo Speer, Michael Böhm, Charlotte M Miller, Florence McCarthy, Jogchum Plat, Dieter Lütjohann, Ulrich Laufs. Vascular effects of oxysterols and oxyphytosterols in apoE -/- mice. Atherosclerosis. 2015 May; 240(1):73-9. doi: 10.1016/j.atherosclerosis.2015.02.032. [PMID: 25765595]
  • Anne Vejux, Thomas Montange, Lucy Martine, Amira Zarrouk, Jean-Marc Riedinger, Gérard Lizard. Absence of oxysterol-like side effects in human monocytic cells treated with phytosterols and oxyphytosterols. Journal of agricultural and food chemistry. 2012 Apr; 60(16):4060-6. doi: 10.1021/jf300487r. [PMID: 22490085]
  • Xiaofeng Niu, Xia Liu, Lan Pan, Lin Qi. [Study on steroids of Sedum lineare]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2011 May; 36(10):1319-21. doi: . [PMID: 21837974]
  • Simin Khaliq, Franz-Josef Volk, August Wilhelm Frahm. Phytochemical investigation of Perovskia abrotanoides. Planta medica. 2007 Jan; 73(1):77-83. doi: 10.1055/s-2006-951766. [PMID: 17315312]
  • Stamatiki Roussi, Francine Gossé, Dalal Aoudé-Werner, Xin Zhang, Philippe Geoffroy, Michel Miesch, Eric Marchioni, Francis Raul. Perturbation of polyamine metabolism and its relation to cell death in human colon cancer cells treated by 7beta-hydroxycholesterol and 7beta-hydroxysitosterol. International journal of oncology. 2006 Dec; 29(6):1549-54. doi: . [PMID: 17088995]
  • Jinyong Peng, Guorong Fan, Yutian Wu. [Studies on chemical constituents of Patrinia villosa Juss]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2005 Oct; 28(10):883-4. doi: ". [PMID: 16479923]
  • S Roussi, A Winter, F Gosse, D Werner, X Zhang, E Marchioni, P Geoffroy, M Miesch, F Raul. Different apoptotic mechanisms are involved in the antiproliferative effects of 7beta-hydroxysitosterol and 7beta-hydroxycholesterol in human colon cancer cells. Cell death and differentiation. 2005 Feb; 12(2):128-35. doi: 10.1038/sj.cdd.4401530. [PMID: 15550935]
  • A T Lehrer, D Dugassa-Gobena, S Vidal, K Seifert. Transport of resistance-inducing sterols in phloem sap of barley. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2000 Nov; 55(11-12):948-52. doi: 10.1515/znc-2000-11-1216. [PMID: 11204200]
  • K M Boberg, E Lund, J Olund, I Björkhem. Formation of C21 bile acids from plant sterols in the rat. The Journal of biological chemistry. 1990 May; 265(14):7967-75. doi: 10.1016/s0021-9258(19)39025-8. [PMID: 2335512]