2-Ethyl-5-methylthiophene (BioDeep_00000615839)
代谢物信息卡片
2-Methyl-5-ethyl-thiophene
化学式: C7H10S (126.0503)
中文名称: 2-乙基-5-甲基噻吩, 2-乙基-5-甲噻吩
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC1=CC=C(S1)C
InChI: InChI=1S/C7H10S/c1-3-7-5-4-6(2)8-7/h4-5H,3H2,1-2H3
描述信息
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Sarah W Robison, JinDong Li, Liliana Viera, Jonathan P Blackburn, Rakesh P Patel, J Edwin Blalock, Amit Gaggar, Xin Xu. A mechanism for matrikine regulation in acute inflammatory lung injury.
JCI insight.
2021 04; 6(7):. doi:
10.1172/jci.insight.140750. [PMID: 33830084] - Yongjun Hu, David E Smith. In Silico Prediction of the Absorption and Disposition of Cefadroxil in Humans using an Intestinal Permeability Method Scaled from Humanized PepT1 Mice.
Drug metabolism and disposition: the biological fate of chemicals.
2019 03; 47(3):173-183. doi:
10.1124/dmd.118.084236. [PMID: 30593545] - Valerie Corvalán, Beatrice Hervé, Camila Sanhueza, Nicolás Martínez, María Almonacid, Sebastián De La Fuente. [Susceptibility to first-generation Cephalosporins in Enterobacteriaceae isolated from urine culture according to CLSI and EUCAST breakpoints].
Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia.
2018 ; 35(3):329-331. doi:
10.4067/s0716-10182018000300329. [PMID: 30534916] - Susanne Johansson, David P Rosenbaum, Johan Palm, Bergur Stefansson, Mikael Knutsson, Eleanor A Lisbon, Constanze Hilgendorf. Tenapanor administration and the activity of the H+ -coupled transporter PepT1 in healthy volunteers.
British journal of clinical pharmacology.
2017 Sep; 83(9):2008-2014. doi:
10.1111/bcp.13313. [PMID: 28432691] - Xiaomei Chen, Richard F Keep, Yan Liang, Hao-Jie Zhu, Margareta Hammarlund-Udenaes, Yongjun Hu, David E Smith. Influence of peptide transporter 2 (PEPT2) on the distribution of cefadroxil in mouse brain: A microdialysis study.
Biochemical pharmacology.
2017 05; 131(?):89-97. doi:
10.1016/j.bcp.2017.02.005. [PMID: 28192085] - Feifeng Song, Yongjun Hu, Huidi Jiang, David E Smith. Species Differences in Human and Rodent PEPT2-Mediated Transport of Glycylsarcosine and Cefadroxil in Pichia Pastoris Transformants.
Drug metabolism and disposition: the biological fate of chemicals.
2017 02; 45(2):130-136. doi:
10.1124/dmd.116.073320. [PMID: 27836942] - Najia Rahim, Syed Baqir Shyum Naqvi, Mehtab Alam, Abdur Rasheed, Urooj Abdul Khalique. Comparative bioavailability and pharmacokinetic study of Cefadroxil capsules in male healthy volunteers of Pakistan.
Pakistan journal of pharmaceutical sciences.
2016 Mar; 29(2):453-9. doi:
NULL. [PMID: 27087092] - Yehua Xie, Hong Shen, Yongjun Hu, Meihua Rose Feng, David E Smith. Population pharmacokinetic modeling of cefadroxil renal transport in wild-type and Pept2 knockout mice.
Xenobiotica; the fate of foreign compounds in biological systems.
2016; 46(4):342-9. doi:
10.3109/00498254.2015.1080881. [PMID: 26372256] - Cecilia Piñera, Francisca Loyola, Pamela Hernández. [Nephronia in pediatrics: part of the spectrum of upper urinary tract infections. Clinical cases and review of the literature].
Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia.
2015 Oct; 32(5):564-8. doi:
10.4067/s0716-10182015000600011. [PMID: 26633114] - Yu Chul Kim, In-Bong Kim, Chi-Kyoung Noh, Holly P Quach, In-Soo Yoon, Edwin C Y Chow, Myungsoo Kim, Hyo-Eon Jin, Kwan Hyung Cho, Suk-Jae Chung, K Sandy Pang, Han-Joo Maeng. Effects of 1α,25-dihydroxyvitamin D3 , the natural vitamin D receptor ligand, on the pharmacokinetics of cefdinir and cefadroxil, organic anion transporter substrates, in rat.
Journal of pharmaceutical sciences.
2014 Nov; 103(11):3793-3805. doi:
10.1002/jps.24195. [PMID: 25266751] - Hyo-Eon Jin, In-Bong Kim, Yu Chul Kim, Kwan Hyung Cho, Han-Joo Maeng. Determination of cefadroxil in rat plasma and urine using LC-MS/MS and its application to pharmacokinetic and urinary excretion studies.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2014 Feb; 947-948(?):103-10. doi:
10.1016/j.jchromb.2013.12.027. [PMID: 24412692] - Yeamin Huh, Richard F Keep, David E Smith. Impact of lipopolysaccharide-induced inflammation on the disposition of the aminocephalosporin cefadroxil.
Antimicrobial agents and chemotherapy.
2013 Dec; 57(12):6171-8. doi:
10.1128/aac.01497-13. [PMID: 24080658] - Maria M Posada, David E Smith. In vivo absorption and disposition of cefadroxil after escalating oral doses in wild-type and PepT1 knockout mice.
Pharmaceutical research.
2013 Nov; 30(11):2931-9. doi:
10.1007/s11095-013-1168-3. [PMID: 23959853] - Maria M Posada, David E Smith. Relevance of PepT1 in the intestinal permeability and oral absorption of cefadroxil.
Pharmaceutical research.
2013 Apr; 30(4):1017-25. doi:
10.1007/s11095-012-0937-8. [PMID: 23224978] - Dirk R de Waart, Koen van de Wetering, Cindy Kunne, Suzanne Duijst, Coen C Paulusma, Ronald P J Oude Elferink. Oral availability of cefadroxil depends on ABCC3 and ABCC4.
Drug metabolism and disposition: the biological fate of chemicals.
2012 Mar; 40(3):515-21. doi:
10.1124/dmd.111.041731. [PMID: 22166395] - Zhuming Wang, Zhenghua Song, Donghua Chen. Study on the binding behavior of bovine serum albumin with cephalosporin analogues by chemiluminescence method.
Talanta.
2010 Dec; 83(2):312-9. doi:
10.1016/j.talanta.2010.09.029. [PMID: 21111139] - Mohamed A Kamal, Richard F Keep, David E Smith. Role and relevance of PEPT2 in drug disposition, dynamics, and toxicity.
Drug metabolism and pharmacokinetics.
2008; 23(4):236-42. doi:
10.2133/dmpk.23.236. [PMID: 18762710] - Eunice Kazue Kano, Valentina Porta, Eunice Emiko Mori Koono, Simone Grigoleto Schramm, Cristina Helena dos Reis Serra. Bioequivalence study of two oral formulations of cefadroxil in healthy volunteers.
Arzneimittel-Forschung.
2008; 58(1):42-7. doi:
10.1055/s-0031-1296465. [PMID: 18368950] - Hong Shen, Scott M Ocheltree, Yongjun Hu, Richard F Keep, David E Smith. Impact of genetic knockout of PEPT2 on cefadroxil pharmacokinetics, renal tubular reabsorption, and brain penetration in mice.
Drug metabolism and disposition: the biological fate of chemicals.
2007 Jul; 35(7):1209-16. doi:
10.1124/dmd.107.015263. [PMID: 17452417] - Branka Bedenic, Marijana Topic, Ana Budimir, Marina Bubonja. Urinary bactericidal activity of oral antibiotics against common urinary tract pathogens in an ex vivo model.
Chemotherapy.
2006; 52(6):293-7. doi:
10.1159/000095969. [PMID: 17008781] - Xiaoli Du, Chonghua Li, Heather K Sun, Charles H Nightingale, David P Nicolau. A sensitive assay of amoxicillin in mouse serum and broncho-alveolar lavage fluid by liquid-liquid extraction and reversed-phase HPLC.
Journal of pharmaceutical and biomedical analysis.
2005 Sep; 39(3-4):648-52. doi:
10.1016/j.jpba.2005.04.021. [PMID: 15935600] - S Otoom, M Hasan, N Najib. Comparative bioavailability of two cefadroxil products using serum and urine data in healthy human volunteers.
Clinical and experimental pharmacology & physiology.
2004 Jul; 31(7):433-7. doi:
10.1111/j.1440-1681.2004.04012.x. [PMID: 15236630] - Suparat Khamdang, Michio Takeda, Ellappan Babu, Rie Noshiro, Maristela Lika Onozato, Akihiro Tojo, Atsushi Enomoto, Xiu-Lin Huang, Shinichi Narikawa, Naohiko Anzai, Pawinee Piyachaturawat, Hitoshi Endou. Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics.
European journal of pharmacology.
2003 Mar; 465(1-2):1-7. doi:
10.1016/s0014-2999(03)01381-5. [PMID: 12650826] - Michio Takeda, Ellappan Babu, Shinichi Narikawa, Hitoshi Endou. Interaction of human organic anion transporters with various cephalosporin antibiotics.
European journal of pharmacology.
2002 Mar; 438(3):137-42. doi:
10.1016/s0014-2999(02)01306-7. [PMID: 11909604] - C H Oliveira, J Salmon, M Sucupira, J Ilha, G De Nucci. Comparative bioavailability of two cefadroxil formulations in healthy human volunteers after a single-dose administration.
Biopharmaceutics & drug disposition.
2000 Sep; 21(6):243-7. doi:
10.1002/bdd.232. [PMID: 11304723] - A El-Gindy, A F El Walily, M F Bedair. First-derivative spectrophotometric and LC determination of cefuroxime and cefadroxil in urine.
Journal of pharmaceutical and biomedical analysis.
2000 Aug; 23(2-3):341-52. doi:
10.1016/s0731-7085(00)00306-x. [PMID: 10933526] - J E Kim, S R Kim, S H Lee, C H Lee, D D Kim. The effect of pore formers on the controlled release of cefadroxil from a polyurethane matrix.
International journal of pharmaceutics.
2000 May; 201(1):29-36. doi:
10.1016/s0378-5173(00)00388-4. [PMID: 10867262] - M E Ganapathy, W Huang, D P Rajan, A L Carter, M Sugawara, K Iseki, F H Leibach, V Ganapathy. beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter.
The Journal of biological chemistry.
2000 Jan; 275(3):1699-707. doi:
10.1074/jbc.275.3.1699. [PMID: 10636865] - M Hefnawy, Y El-Shabrawy, F Belal. Spectrofluorometric determination of alpha-aminocephalosporins in biological fluids and pharmaceutical preparations.
Journal of pharmaceutical and biomedical analysis.
1999 Dec; 21(4):703-7. doi:
10.1016/s0731-7085(99)00208-3. [PMID: 10701934] - N Shetty, R I Shulman, G M Scott. An audit of first generation cephalosporin usage.
The Journal of hospital infection.
1999 Mar; 41(3):229-32. doi:
10.1016/s0195-6701(99)90021-x. [PMID: 10204126] - H Carsenti-Etesse, R Farinotti, J Durant, P M Roger, F De Salvador, E Bernard, B Rouveix, P Dellamonica. Pharmacokinetic parameters and killing rates in serum of volunteers receiving amoxicillin, cefadroxil or cefixime alone or associated with niflumic acid or paracetamol.
European journal of drug metabolism and pharmacokinetics.
1998 Jul; 23(3):357-66. doi:
10.1007/bf03192294. [PMID: 9842977] - N E Duffee, B E Stang, D J Schaeffer. The pharmacokinetics of cefadroxil over a range of oral doses and animal ages in the foal.
Journal of veterinary pharmacology and therapeutics.
1997 Dec; 20(6):427-33. doi:
10.1046/j.1365-2885.1997.00085.x. [PMID: 9430765] - I Adamsson, C Edlund, S Sjöstedt, C E Nord. Comparative effects of cefadroxil and phenoxymethylpenicillin on the normal oropharyngeal and intestinal microflora.
Infection.
1997 May; 25(3):154-8. doi:
10.1007/bf02113603. [PMID: 9181382] - N Selvakumar, V Kumar, C N Paramasivan. In vitro susceptibility of clinical isolates of Mycobacterium tuberculosis to cefadroxil--a cephalosporin antibiotic.
The Indian journal of medical research.
1997 Feb; 105(?):58-60. doi:
NULL. [PMID: 9055496] - R H Barbhaiya. A pharmacokinetic comparison of cefadroxil and cephalexin after administration of 250, 500 and 1000 mg solution doses.
Biopharmaceutics & drug disposition.
1996 May; 17(4):319-30. doi:
10.1002/(sici)1099-081x(199605)17:4<319::aid-bdd957>3.0.co;2-w. [PMID: 8743403] - P Muth, R Metz, H Beck, W W Bolten, H Vergin. Improved high-performance liquid chromatographic determination of amoxicillin in human plasma by means of column switching.
Journal of chromatography. A.
1996 Apr; 729(1-2):259-66. doi:
10.1016/0021-9673(95)01021-1. [PMID: 9004948] - M J Gimeno, M Martínez, L Granero, F Torres-Molina, J E Peris. Influence of probenecid on the renal excretion mechanisms of cefadroxil.
Drug metabolism and disposition: the biological fate of chemicals.
1996 Feb; 24(2):270-2. doi:
NULL. [PMID: 8742242] - M Boll, M Herget, M Wagener, W M Weber, D Markovich, J Biber, W Clauss, H Murer, H Daniel. Expression cloning and functional characterization of the kidney cortex high-affinity proton-coupled peptide transporter.
Proceedings of the National Academy of Sciences of the United States of America.
1996 Jan; 93(1):284-9. doi:
10.1073/pnas.93.1.284. [PMID: 8552623] - Z Yuan, H Q Russlie, D M Canafax. Sensitive assay for measuring amoxicillin in human plasma and middle ear fluid using solid-phase extraction and reversed-phase high-performance liquid chromatography.
Journal of chromatography. B, Biomedical applications.
1995 Dec; 674(1):93-9. doi:
10.1016/0378-4347(95)00302-1. [PMID: 8749256] - M E Ganapathy, M Brandsch, P D Prasad, V Ganapathy, F H Leibach. Differential recognition of beta -lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2.
The Journal of biological chemistry.
1995 Oct; 270(43):25672-7. doi:
10.1074/jbc.270.43.25672. [PMID: 7592745] - M Boll, H Daniel. Target size analysis of the peptide/H(+)-symporter in kidney brush-border membranes.
Biochimica et biophysica acta.
1995 Feb; 1233(2):145-52. doi:
10.1016/0005-2736(94)00245-k. [PMID: 7865539] - N Snippe, N C van de Merbel, F P Ruiter, O M Steijger, H Lingeman, U A Brinkman. Automated column liquid chromatographic determination of amoxicillin and cefadroxil in bovine serum and muscle tissue using on-line dialysis for sample preparation.
Journal of chromatography. B, Biomedical applications.
1994 Dec; 662(1):61-70. doi:
10.1016/0378-4347(94)00377-7. [PMID: 7894694] - M Ries, U Wenzel, H Daniel. Transport of cefadroxil in rat kidney brush-border membranes is mediated by two electrogenic H+-coupled systems.
The Journal of pharmacology and experimental therapeutics.
1994 Dec; 271(3):1327-33. doi:
NULL. [PMID: 7996442] - L Granero, M J Gimeno, F Torres-Molina, J Chesa-Jiménez, J E Peris. Studies on the renal excretion mechanisms of cefadroxil.
Drug metabolism and disposition: the biological fate of chemicals.
1994 May; 22(3):447-50. doi:
NULL. [PMID: 8070323] - Y Akimoto, M Komiya, K Kaneko, A Fujii. Cefadroxil concentrations in human serum, gingiva, and mandibular bone following a single oral administration.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.
1994 Apr; 52(4):397-400; discussion 400. doi:
10.1016/0278-2391(94)90447-2. [PMID: 8133373] - J A Klein. Tumescent technique for local anesthesia improves safety in large-volume liposuction.
Plastic and reconstructive surgery.
1993 Nov; 92(6):1085-98; discussion 1099. doi:
10.1097/00006534-199311000-00014. [PMID: 8234507] - A T Tang, Y L Lau, B Jones, G M Halpern, C Y Yeung. Cefadroxil reduces the production of IgE in a 3 year old asthmatic with juvenile rheumatoid arthritis.
Allergologia et immunopathologia.
1993 Jul; 21(4):131-5. doi:
. [PMID: 8237716] - B Charles, S Chulavatnatol. Simple analysis of amoxycillin in plasma by high performance liquid chromatography with internal standardization and ultraviolet detection.
Biomedical chromatography : BMC.
1993 Jul; 7(4):204-7. doi:
10.1002/bmc.1130070407. [PMID: 8219698] - T Miyakawa, W Zhang, T Uchida, N S Kim, S Goto. In vivo release of water-soluble drugs from stabilized water-in-oil-in-water (W/O/W) type multiple emulsions following intravenous administrations using rats.
Biological & pharmaceutical bulletin.
1993 Mar; 16(3):268-72. doi:
10.1248/bpb.16.268. [PMID: 8364471] - M C García-Carbonell, L Granero, F Torres-Molina, J C Aristorena, J Chesa-Jiménez, J M Plá-Delfina, J E Peris-Ribera. Nonlinear pharmacokinetics of cefadroxil in the rat.
Drug metabolism and disposition: the biological fate of chemicals.
1993 Mar; 21(2):215-7. doi:
NULL. [PMID: 8097688] - P Dellamonica, R Garraffo, H Etesse-Carsenti, E Bernard, V Mondain. Pharmacokinetic and bacteriological study of cefadroxil-salicylate and josamycin-salicylate drug regimens.
International journal of clinical pharmacology research.
1993; 13(1):11-20. doi:
NULL. [PMID: 8509232] - T Uchida, T Yasutake, S Goto. Utility of mixture of commercially available polymers as constituents of sustained-release microcapsules containing cefadroxil or theophylline.
Chemical & pharmaceutical bulletin.
1992 Feb; 40(2):463-6. doi:
10.1248/cpb.40.463. [PMID: 1606646] - K S Nungu, S Bengtsson, C Olerud, L Rehnberg, S Larsson. Oral cefadroxil prophylaxis in hip fracture surgery. Serum concentrations studied in 17 patients.
Acta orthopaedica Scandinavica.
1992 Feb; 63(1):4-6. doi:
10.3109/17453679209154839. [PMID: 1738968] - H Etesse-Carsenti, R Garraffo, E Bernard, F de Salvador, C Pradier, J Durant, V Mondain, H B Drugeon, P Dellamonica. [Bactericidal effect of cefadroxil, amoxicillin alone or in combination with clavulanic acid in sera of healthy volunteers].
Pathologie-biologie.
1991 Dec; 39(10):972-7. doi:
. [PMID: 1805138] - M F Barkworth, B Mangold, K D Rehm, G Schmieder, H Töberich, A Vinchenzo, J Weber, C Rübartsch. [The biological availability of cefadroxil given simultaneously with N-acetylcysteine].
Arzneimittel-Forschung.
1991 Aug; 41(8):839-43. doi:
NULL. [PMID: 1781807] - J P Barrio Lera, A I Alvarez, J G Prieto. Effects of ethanol on the pharmacokinetics of cephalexin and cefadroxil in the rat.
Journal of pharmaceutical sciences.
1991 Jun; 80(6):511-6. doi:
10.1002/jps.2600800602. [PMID: 1941538] - T M Garrigues, U Martin, J E Peris-Ribera, L F Prescott. Dose-dependent absorption and elimination of cefadroxil in man.
European journal of clinical pharmacology.
1991; 41(2):179-83. doi:
10.1007/bf00265914. [PMID: 1743250] - V Tzias, A S Dontas, G Petrikkos, M Papapetropoulou, J Dracopoulos, H Giamarellou. Three-day antibiotic therapy in bacteriuria of old age.
The Journal of antimicrobial chemotherapy.
1990 Nov; 26(5):705-11. doi:
10.1093/jac/26.5.705. [PMID: 2079452] - H Nakanomyo, M Hiraoka, M Kidono. [Microbiological assay method of BMY-28100 and some other cephem antibiotic in serum and tissues. Development of new sample preparation with Evan's blue, a high albumin binding dye].
The Japanese journal of antibiotics.
1990 Sep; 43(9):1538-44. doi:
. [PMID: 2262961] - S G Bragman, M W Casewell. The in-vitro activity of ceftibuten against 475 clinical isolates of gram-negative bacilli, compared with cefuroxime and cefadroxil.
The Journal of antimicrobial chemotherapy.
1990 Feb; 25(2):221-6. doi:
10.1093/jac/25.2.221. [PMID: 2329100] - C Stathakis, N Roulleau, M Libert, G Germano, M Kissling. Cefetamet pivoxil in acute pyelonephritis: an open study.
Current medical research and opinion.
1990; 12(1):43-50. doi:
10.1185/03007999009111490. [PMID: 2188796] - M C Nahata, D S Jackson, D A Powell. Cefadroxil kinetics and dynamics in a pediatric patient with acute osteomyelitis.
Chemotherapy.
1990; 36(6):392-5. doi:
10.1159/000238794. [PMID: 2292202] - A Sánchez-Picó, J E Peris-Ribera, C Toledano, F Torres-Molina, V G Casabó, A Martín-Villodre, J M Plá-Delfina. Non-linear intestinal absorption kinetics of cefadroxil in the rat.
The Journal of pharmacy and pharmacology.
1989 Mar; 41(3):179-85. doi:
10.1111/j.2042-7158.1989.tb06425.x. [PMID: 2568445] - H Wedrén. On chronic prostatitis with special studies of Staphylococcus epidermidis.
Scandinavian journal of urology and nephrology. Supplementum.
1989; 123(?):1-36. doi:
NULL. [PMID: 2483757] - A Strömberg, U Friberg, O Cars. Concentrations of phenoxymethylpenicillin and cefadroxil in tonsillar tissue and tonsillar surface fluid.
European journal of clinical microbiology.
1987 Oct; 6(5):525-9. doi:
10.1007/bf02014240. [PMID: 3125047] - J A McAteer, M F Hiltke, B M Silber, R D Faulkner. Liquid-chromatographic determination of five orally active cephalosporins--cefixime, cefaclor, cefadroxil, cephalexin, and cephradine--in human serum.
Clinical chemistry.
1987 Oct; 33(10):1788-90. doi:
. [PMID: 3665031] - S Soback, G Ziv, B Kurtz, R Paz. Clinical pharmacokinetics of five oral cephalosporins in calves.
Research in veterinary science.
1987 Sep; 43(2):166-72. doi:
10.1016/s0034-5288(18)30767-7. [PMID: 3317582] - K Lindgren. Determination of cefadroxil in serum by high-performance liquid chromatography with cephradine as internal standard.
Journal of chromatography.
1987 Jan; 413(?):347-50. doi:
10.1016/0378-4347(87)80252-9. [PMID: 3558690] - N Minkov, Z Zlatanov, B Zozikov, D Khristova. [Treatment of urinary infection with cephadroxyl (Pharmachem)--microbiological and clinical research].
Vutreshni bolesti.
1987; 26(5):98-104. doi:
NULL. [PMID: 3433735] - D R Chisholm, R G DeRegis, D A Behr. Therapeutic efficacy of cefadroxil and cephalexin for pneumonia in a rat test model.
Antimicrobial agents and chemotherapy.
1986 Jul; 30(1):105-9. doi:
10.1128/aac.30.1.105. [PMID: 3752972] - B Tanrisever, P J Santella. Cefadroxil. A review of its antibacterial, pharmacokinetic and therapeutic properties in comparison with cephalexin and cephradine.
Drugs.
1986; 32 Suppl 3(?):1-16. doi:
10.2165/00003495-198600323-00003. [PMID: 3542485] - C H Nightingale. Penetration and concentration of cefadroxil in sputum, lung and pleural fluid.
Drugs.
1986; 32 Suppl 3(?):17-20. doi:
10.2165/00003495-198600323-00004. [PMID: 3803249] - W D Wilson, J D Baggot, P J Adamson, D C Hirsh, S K Hietala. Cefadroxil in the horse: pharmacokinetics and in vitro antibacterial activity.
Journal of veterinary pharmacology and therapeutics.
1985 Sep; 8(3):246-53. doi:
10.1111/j.1365-2885.1985.tb00953.x. [PMID: 4057345] - P G Welling, A Selen, J G Pearson, F Kwok, M C Rogge, A Ifan, D Marrero, W A Craig, C A Johnson. A pharmacokinetic comparison of cephalexin and cefadroxil using HPLC assay procedures.
Biopharmaceutics & drug disposition.
1985 Apr; 6(2):147-57. doi:
10.1002/bdd.2510060206. [PMID: 4005394] - Y Akimoto, H Nishimura, M Komiya, T Shibata, K Kaneko, A Fujii, T Tamura. Concentrations of ampicillin and cefadroxil in human serum and mixed saliva following a single oral administration of talampicillin and cefadroxil, and relationships between serum and mixed saliva concentrations.
General pharmacology.
1985; 16(3):273-5. doi:
10.1016/0306-3623(85)90082-5. [PMID: 4018542] - K Malaka-Zafiriu, F Papadopoulos, P Avgoustidou-Savopoulou, F Papachristos. Comparison of cefadroxil and ampicillin in the treatment of urinary tract infections in children.
Clinical therapeutics.
1984; 6(2):178-84. doi:
. [PMID: 6705012] - J Degen, L Ringwelski, H Maier-Lenz. [Concentration of cefadroxil in kidney tissue and serum after oral administration in patients with normal and impaired renal function].
Arzneimittel-Forschung.
1983; 33(9):1339-42. doi:
NULL. [PMID: 6685518] - B Hampel, H Lode, J Wagner, P Koeppe. Pharmacokinetics of cefadroxil and cefaclor during an eight-day dosage period.
Antimicrobial agents and chemotherapy.
1982 Dec; 22(6):1061-3. doi:
10.1128/aac.22.6.1061. [PMID: 7159069] - A Leroy, G Humbert, M Godin, J P Fillastre. Pharmacokinetics of cefadroxil in patients with impaired renal function.
The Journal of antimicrobial chemotherapy.
1982 Sep; 10 Suppl B(?):39-46. doi:
10.1093/jac/10.suppl_b.39. [PMID: 7142092] - R B Wilber, R G DeRegis, E J Fox. The role of cefadroxil in the therapy of urinary tract infections.
The Journal of antimicrobial chemotherapy.
1982 Sep; 10 Suppl B(?):77-84. doi:
10.1093/jac/10.suppl_b.77. [PMID: 7142098] - F La Rosa, S Ripa, M Prenna, A Ghezzi, M Pfeffer. Pharmacokinetics of cefadroxil after oral administration in humans.
Antimicrobial agents and chemotherapy.
1982 Feb; 21(2):320-2. doi:
10.1128/aac.21.2.320. [PMID: 7073267] - E L Mariño, A Dominguez-Gil, C Muriel. Influence of dosage form and administration route on the pharmacokinetic parameters of cefadroxil.
International journal of clinical pharmacology, therapy, and toxicology.
1982 Feb; 20(2):73-7. doi:
NULL. [PMID: 7061182] - E L Mariño, A Dominguez-Gil. The pharmacokinetics of cefadroxil associated with probenecid.
International journal of clinical pharmacology, therapy, and toxicology.
1981 Nov; 19(11):506-8. doi:
NULL. [PMID: 6795136] - G H McCracken, C M Ginsburg, V Namasonthi, M Petruska. Evaluation of short-term antibiotic therapy in children with uncomplicated urinary tract infections.
Pediatrics.
1981 Jun; 67(6):796-801. doi:
. [PMID: 7015262] - M Minamitani, K Hachimori, H Nakazawa, N Tomori. [Therapeutic experience with cefadroxil syrup in acute infections, especially scarlet fever, in pediatric field (author's transl)].
The Japanese journal of antibiotics.
1981 Feb; 34(2):161-70. doi:
. [PMID: 7253196] - S Nakazawa, H Sato, K Niino, S Nakazawa, H Suzuki, A Iwasaki, Y Hirama, A Narita, H Chikaoka, T Yamaguchi. [Some investigations on cefadroxil dry syrup (author's transl)].
The Japanese journal of antibiotics.
1981 Feb; 34(2):171-9. doi:
. [PMID: 7253197] - M Takimoto, K Cho, H Yoshioka, N Sanae, S Maruyama. [Clinical results of cefadroxil in children and pharmacokinetics of the drug (author's transl)].
The Japanese journal of antibiotics.
1981 Feb; 34(2):140-2. doi:
. [PMID: 7253191] - T Shinozaki, K Komaki, S Hashira, R Fujii. [Clinical results of cefadroxil in pediatric field (author's transl)].
The Japanese journal of antibiotics.
1981 Feb; 34(2):146-51. doi:
. [PMID: 7253193] - T Nishimura, K Kiromatsu, T Takashima, K Tabuki, Y Kotani. [Laboratory and clinical studies of cefadroxil (author's transl)].
The Japanese journal of antibiotics.
1981 Jan; 34(1):41-50. doi:
. [PMID: 7017197] - Y Kobayashi, Y Morikawa, T Haruta, T Fujiwara. [Fundamental and clinical studies on cefadroxil dry syrup in children (author's transl)].
The Japanese journal of antibiotics.
1981 Jan; 34(1):33-40. doi:
. [PMID: 7241805] - M Hori, Y Toyonaga, Y Kurosu, K Kumagai. [Laboratory and clinical studies on cefadroxil in the field of pediatrics (author's transl)].
The Japanese journal of antibiotics.
1981 Jan; 34(1):61-76. doi:
. [PMID: 7241807] - N Iwai, A Sasaki, M Miyazu, T Osuga. [Laboratory and clinical studies on cefadroxil in the field of pediatrics (author's transl)].
The Japanese journal of antibiotics.
1981 Jan; 34(1):77-94. doi:
. [PMID: 7241809] - E L Mariño, A A Dominguez-Gil, M Cepeda, M J Otero, A Dominguez-Gil. Effect of experimentally induced renal impairment on the pharmacokinetics of cefadroxil in rabbits.
Arzneimittel-Forschung.
1981; 31(3):478-81. doi:
NULL. [PMID: 7194673] - E L Mariño, M Pajares, A A Dominguez-Gil, M Cepeda, A Dominguez-Gil. Disposition of cefadroxil administered orally to rabbits with experimentally induced renal impairment.
Arzneimittel-Forschung.
1981; 31(9):1459-61. doi:
NULL. [PMID: 7197955] - E L Mariño, A Dominguez-Gil. Influence of dose on the pharmacokinetics of cefadroxil.
European journal of clinical pharmacology.
1980 Nov; 18(6):505-9. doi:
10.1007/bf00874664. [PMID: 7461017] - H Nakanomyo, K Imai, M Hiraoka, Y Hasegawa. [Microbiological assay method of cefadroxil in biological specimens (author's transl)].
The Japanese journal of antibiotics.
1980 Aug; 33(8):767-72. doi:
NULL. [PMID: 7206222] - H Nakanomyo, K Imai, M Hiraoka, Y Hasegawa. [Pharmacokinetics of cefadroxil in rats: comparison of fasting and non-fasting (author's transl)].
The Japanese journal of antibiotics.
1980 Aug; 33(8):778-81. doi:
NULL. [PMID: 7206224] - H Nakanomyo, K Imai, M Hiraoka, Y Hasegawa. [Studied on protein binding of cefadroxil and some other cephalosporins (author's transl)].
The Japanese journal of antibiotics.
1980 Aug; 33(8):773-7. doi:
NULL. [PMID: 7206223] - M Kodama, M Fujii, M Hayashi. [Clinical experience with cefadroxil for acute simple cystitis (author's transl)].
The Japanese journal of antibiotics.
1980 Mar; 33(3):367-70. doi:
NULL. [PMID: 7401311]
