Betazole (BioDeep_00000614938)
Volatile Flavor Compounds
代谢物信息卡片
化学式: C5H9N3 (111.07964340000001)
中文名称: 倍他唑
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=C(NN=C1)CCN
InChI: InChI=1S/C5H9N3/c6-3-1-5-2-4-7-8-5/h2,4H,1,3,6H2,(H,7,8)
描述信息
V - Various > V04 - Diagnostic agents > V04C - Other diagnostic agents > V04CG - Tests for gastric secretion
D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D017442 - Histamine Agonists
D005765 - Gastrointestinal Agents
Betazole (Ametazole), a pyrazole analogue of histamine, is an orally active histamine H2 receptor agonist. Betazole induces gastric acid secretion and causes an immediate and significant increase in common bile duct pressure. Betazole is used as a diagnostic agent known as histalog for investigating gastric acid secretory capacity[1][2][3].
同义名列表
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:59170
- PubChem: 7741
- Metlin: METLIN85355
- DrugBank: DB00272
- ChEMBL: CHEMBL1201323
- MeSH: Betazole
- CAS: 105-20-4
- medchemexpress: HY-B1557
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- J R M da Rocha, U Ribeiro, I Cecconello, R A A Sallum, F Takeda, A Nasi, S Szachnowicz. Gastric secretory and hormonal patterns in end-stage chagasic achalasia.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus.
2009; 22(7):606-10. doi:
10.1111/j.1442-2050.2009.00961.x
. [PMID: 19302218] - P Engler-Pinto Júnior, J Gama-Rodrigues, F P Lopasso, A C Cordeiro, A Saez-Alquezar, A A Laudanna, H W Pinotti. Site of peptic ulcer. comparison of hydrochloric acid output, pepsinogen and gastrin serum levels.
Hepato-gastroenterology.
1996 Nov; 43(12):1671-7. doi:
NULL
. [PMID: 8975987] - L A D'Albuquerque, J G Rodrigues, P Albornoz, M P De Miranda, T Genzini, H W Pinotti. Serum pepsinogen before and after proximal gastric vagotomy in duodenal ulcer treatment.
International surgery.
1989 Oct; 74(4):229-31. doi:
NULL
. [PMID: 2625397] - E Z Dajani. Perspective on the gastric antisecretory effects of misoprostol in man.
Prostaglandins.
1987; 33 Suppl(?):68-77. doi:
10.1016/0090-6980(87)90050-5
. [PMID: 3122277] - P S Key, N D Vaziri, M Childester. Effect of H2 histamine receptor blockade and stimulation on urinary acidification.
General pharmacology.
1985; 16(6):621-3. doi:
10.1016/0306-3623(85)90154-5
. [PMID: 4085782] - H Sasaki, M Nagulesparan, I M Samloff, E Straus, M L Sievers, A Dubois. Low acid output in Pima Indians. A possible cause for the rarity of duodenal ulcer in this population.
Digestive diseases and sciences.
1984 Sep; 29(9):785-9. doi:
10.1007/bf01318419
. [PMID: 6468210] - H Sasaki, M Nagulesparan, A Dubois, I M Samloff, E Straus, M L Sievers, R H Unger. Gastric function and obesity: gastric emptying, gastric acid secretion, and plasma pepsinogen.
International journal of obesity.
1984; 8(2):183-90. doi:
NULL
. [PMID: 6724800] - B Kihl, A Rökaeus, S Rosell, L Olbe. The effect of intraduodenal installation of oleic acid on plasma neurotensin-like immunoreactivity and on gastric acid secretion stimulated by betazole and sham feeding in man.
Scandinavian journal of gastroenterology.
1982 Aug; 17(5):633-9. doi:
10.3109/00365528209181071
. [PMID: 7178827] - I M Schöön, S R Bloom, L Olbe. The effect of antral distension in healthy subjects on betazole-stimulated gastric acid secretion and the plasma concentration of immunoreactive neurotensin.
Scandinavian journal of gastroenterology.
1980; 15(3):277-82. doi:
10.3109/00365528009181470
. [PMID: 7433886] - D K Kim, M K Schwartz, P Sherlock. The two stage provocative test for pancreatic disease by serum enzyme measurements.
Surgery, gynecology & obstetrics.
1980 Jan; 150(1):49-53. doi:
NULL
. [PMID: 7350701] - J R Malagelada. Pathophysiological responses to meals in the Zollinger-Ellison syndrome: I. Paradoxical postprandial inhibition of gastric secretion.
Gut.
1978 Apr; 19(4):284-9. doi:
10.1136/gut.19.4.284
. [PMID: 25828] - J R Malagelada, G F Longstreth, T B Deering, W H Summerskill, V L Go. Gastric secretion and emptying after ordinary meals in duodenal ulcer.
Gastroenterology.
1977 Nov; 73(5):989-94. doi:
NULL
. [PMID: 332582] - R H Bower, J Sode, W H Lipshutz. Cyclic adenosine monophosphate and human gastric acid secretion.
The American journal of digestive diseases.
1977 Aug; 22(8):705-11. doi:
10.1007/bf01078350
. [PMID: 195465] - P Kownin, K Limwongs, P Visutakul, A Pauswasdi, P Phornpibul, S Tongprasroet. Fasting serum gastrin and augmented histalog test in normal Thai subjects and in patients with peptic ulcer.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet.
1977 Aug; 60(8):362-7. doi:
NULL
. [PMID: 908898] - I M Samloff, D M Secrist, E Passaro. Effect of betazole on serum group I pepsinogen levels: relationship to gastric acid output in unoperated and postoperative patients.
Gastroenterology.
1977 May; 72(5 Pt 1):845-8. doi:
10.1016/s0016-5085(77)80198-4
. [PMID: 849814] - W Hughes, S Cohen, D Arvan, B Seamonds. The effect of the alkaline tide on serum-ionized calcium concentration in man.
Digestion.
1977; 15(3):175-81. doi:
10.1159/000198001
. [PMID: 14862] - I M Samloff, D M Secrist, E Passaro. The effect of betazole on serum group I pepsinogen levels: studies in symptomatic patients with and without recurrent ulcer after vagotomy and gastric resection or drainage.
Gastroenterology.
1976 Jun; 70(6):1007-13. doi:
NULL
. [PMID: 1269860] - H P Norberg, J A Schulak, B Atlas, E L Kaplan. Histamine-induced hypocalcemia in the rat.
Metabolism: clinical and experimental.
1976 Feb; 25(2):131-4. doi:
10.1016/0026-0495(76)90042-1
. [PMID: 1250153] - K J Ivey, J Hansky. Variability of serum gastrin levels in Zollinger-Ellison syndrome. Studies with two antisera to gastrin.
The American journal of digestive diseases.
1975 Jun; 20(6):513-17. doi:
10.1007/bf01074935
. [PMID: 1130377]