Methcathinone (BioDeep_00000614827)
Main id: BioDeep_00000017851
代谢物信息卡片
Methcathinone
化学式: C10H13NO (163.0997)
中文名称: 甲卡西酮, 甲基卡西酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C(=O)C1=CC=CC=C1)NC
InChI: InChI=1S/C10H13NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,11H,1-2H3
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:149677
- PubChem: 1576
- Metlin: METLIN85213
- DrugBank: DB15339
- ChEMBL: CHEMBL4070364
- CAS: 5650-44-2
- KEGG: C22783
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Hong-Fei Shi, Bo-Peng Xu, Cheng-Xin Xu, Xiu-Qi Zhou, Hong-Fu Xu. [Rapid extraction and detection of five alkaloids in dried khat by solvent extraction-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry].
Se pu = Chinese journal of chromatography.
2023 Sep; 41(9):771-780. doi:
10.3724/sp.j.1123.2023.03009. [PMID: 37712541] - Charlotte P Magee, BaoMinh D Le, Yasmeen H Siripathane, Diana G Wilkins, Glen R Hanson, Annette E Fleckenstein. Methcathinone decreases dopamine transporter function: Role of protein kinase C.
Journal of neurochemistry.
2021 10; 159(1):116-127. doi:
10.1111/jnc.15483. [PMID: 34320222] - Dongxian Liu, Erli Zhang, Mingming Zhao, Yuli Tian, Mingkun Yang, Yong Wang. Pharmacokinetics and tissue distribution of methcathinone in rabbits.
Legal medicine (Tokyo, Japan).
2021 Jul; 51(?):101876. doi:
10.1016/j.legalmed.2021.101876. [PMID: 33853008] - Yousef A Bin Jardan, Khaled Mohamed, Nagwan Abbas, Manal El-Gendy, Nawaf Alsaif, Mohammed Alanazi, Mostafa Mohammed, Mohammed Abounassif, Mohamed Hefnawy. Development and validation of GC-MS method for determination of methcathinone and its main metabolite in mice plasma and brain tissue after SPE: Pharmacokinetic and distribution study.
Journal of pharmaceutical and biomedical analysis.
2021 Feb; 194(?):113798. doi:
10.1016/j.jpba.2020.113798. [PMID: 33298381] - Rachel A Davies, Tyson R Baird, Vy T Nguyen, Brian Ruiz, Farhana Sakloth, Jose M Eltit, S Stevens Negus, Richard A Glennon. Investigation of the Optical Isomers of Methcathinone, and Two Achiral Analogs, at Monoamine Transporters and in Intracranial Self-Stimulation Studies in Rats.
ACS chemical neuroscience.
2020 06; 11(12):1762-1769. doi:
10.1021/acschemneuro.9b00617. [PMID: 32356961] - Yu Chen, Huyen T N Tran, Yasir H Saber, F Scott Hall. High ambient temperature increases the toxicity and lethality of 3,4-methylenedioxymethamphetamine and methcathinone.
Pharmacology, biochemistry, and behavior.
2020 05; 192(?):172912. doi:
10.1016/j.pbb.2020.172912. [PMID: 32201298] - Xun Zhou, Jamal Bouitbir, Matthias E Liechti, Stephan Krähenbühl, Riccardo V Mancuso. Hyperthermia Increases Neurotoxicity Associated with Novel Methcathinones.
Cells.
2020 04; 9(4):. doi:
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Neuropharmacology.
2019 12; 161(?):107615. doi:
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2019 Sep; 125(3):253-258. doi:
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2019 01; 10(1):740-745. doi:
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2015 Sep; 87(18):9500-6. doi:
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2015 May; 172(10):2433-44. doi:
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British journal of pharmacology.
2015 May; 172(9):2210-8. doi:
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2014 Jul; 28(3):338-43. doi:
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2013 Jun; 85(12):1803-15. doi:
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European journal of neurology.
2013 Jun; 20(6):915-20. doi:
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European journal of pharmacology.
2013 Jan; 699(1-3):180-7. doi:
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2012 Jun; 4(6):402-8. doi:
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Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
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2012 Mar; 120(6):1097-107. doi:
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PloS one.
2012; 7(8):e44652. doi:
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2011 Nov; 339(2):530-6. doi:
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