Sapienic acid (BioDeep_00000607085)
Main id: BioDeep_00000628732
代谢物信息卡片
化学式: C16H30O2 (254.224568)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCC/C=C\CCCCC(=O)O
InChI: InChI=1S/C16H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h10-11H,2-9,12-15H2,1H3,(H,17,18)/b11-10-
描述信息
A hexadecenoic acid in which the double bond is located at position 6 (the Z-geoisomer). A major component of human sebaceous lipids that is involved in skin self-sterilisation and atopic dermatitis amelioration.
同义名列表
3 个代谢物同义名
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:76244
- KEGG: C21942
- PubChem: 5312419
- Metlin: METLIN73942
- CAS: 17004-51-2
- MetaboLights: MTBLC76244
- PubChem: 376218975
- LipidMAPS: LMFA01030267
- PDB-CCD: 8Z9
- RefMet: Sapienic acid
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ertan Küçüksayan, Anna Sansone, Chryssostomos Chatgilialoglu, Tomris Ozben, Demet Tekeli, Günel Talibova, Carla Ferreri. Sapienic Acid Metabolism Influences Membrane Plasticity and Protein Signaling in Breast Cancer Cell Lines.
Cells.
2022 01; 11(2):. doi:
10.3390/cells11020225. [PMID: 35053341] - Mouna Triki, Gianmarco Rinaldi, Melanie Planque, Dorien Broekaert, Alina M Winkelkotte, Carina R Maier, Sudha Janaki Raman, Anke Vandekeere, Joke Van Elsen, Martin F Orth, Thomas G P Grünewald, Almut Schulze, Sarah-Maria Fendt. mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.
Cell reports.
2020 06; 31(12):107806. doi:
10.1016/j.celrep.2020.107806. [PMID: 32579932] - Roberta Scanferlato, Massimo Bortolotti, Anna Sansone, Chryssostomos Chatgilialoglu, Letizia Polito, Marco De Spirito, Giuseppe Maulucci, Andrea Bolognesi, Carla Ferreri. Hexadecenoic Fatty Acid Positional Isomers and De Novo PUFA Synthesis in Colon Cancer Cells.
International journal of molecular sciences.
2019 Feb; 20(4):. doi:
10.3390/ijms20040832. [PMID: 30769921] - Anna Sansone, Evanthia Tolika, Maria Louka, Valentina Sunda, Simone Deplano, Michele Melchiorre, Dimitrios Anagnostopoulos, Chryssostomos Chatgilialoglu, Cesare Formisano, Rosa Di Micco, Maria Rosaria Faraone Mennella, Carla Ferreri. Hexadecenoic Fatty Acid Isomers in Human Blood Lipids and Their Relevance for the Interpretation of Lipidomic Profiles.
PloS one.
2016; 11(4):e0152378. doi:
10.1371/journal.pone.0152378. [PMID: 27045677] - Carol L Fischer, Deborah V Dawson, Derek R Blanchette, David R Drake, Philip W Wertz, Kim A Brogden. Protein Analysis of Sapienic Acid-Treated Porphyromonas gingivalis Suggests Differential Regulation of Multiple Metabolic Pathways.
Journal of bacteriology.
2016 01; 198(1):157-67. doi:
10.1128/jb.00665-15. [PMID: 26483519] - Sanganamoni Chinna Gopal, Shiva Shanker Kaki, Bhamidipati V S K Rao, Yedla Poornachandra, Chityal Ganesh Kumar, Rachapudi Badari Narayana Prasad. Synthesis of novel lipoamino acid conjugates of sapienic acid and evaluation of their cytotoxicity activities.
Journal of oleo science.
2014; 63(7):717-22. doi:
10.5650/jos.ess13218. [PMID: 24919473] - E B Cahoon, A M Cranmer, J Shanklin, J B Ohlrogge. delta 6 Hexadecenoic acid is synthesized by the activity of a soluble delta 6 palmitoyl-acyl carrier protein desaturase in Thunbergia alata endosperm.
The Journal of biological chemistry.
1994 Nov; 269(44):27519-26. doi:
10.1016/s0021-9258(18)47015-9. [PMID: 7961667] - . .
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. doi:
. [PMID: 30728499]