Olvanil (BioDeep_00000605911)
代谢物信息卡片
化学式: C26H43NO3 (417.3242768)
中文名称: 奥伐尼
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCC=CCCCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
InChI: InChI=1S/C26H43NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-26(29)27-22-23-19-20-24(28)25(21-23)30-2/h10-11,19-21,28H,3-9,12-18,22H2,1-2H3,(H,27,29)/b11-10-
描述信息
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D000893 - Anti-Inflammatory Agents
D018501 - Antirheumatic Agents
同义名列表
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:177616
- KEGGdrug: D05249
- PubChem: 5311093
- Metlin: METLIN64924
- ChEMBL: CHEMBL76903
- CAS: 58493-49-5
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Kenji Kobata, Ikue Takemura, Gaku Tago, Takayuki Moriya, Kaori Kubota, Sachie Nakatani, Masahiro Wada, Tatsuo Watanabe. Formation of long-chain N-vanillyl-acylamides from plant oils.
Bioscience, biotechnology, and biochemistry.
2014; 78(7):1242-5. doi:
10.1080/09168451.2014.912118. [PMID: 25229865] - David A Barrière, Christophe Mallet, Anders Blomgren, Charlotte Simonsen, Laurence Daulhac, Frédéric Libert, Eric Chapuy, Monique Etienne, Edward D Högestätt, Peter M Zygmunt, Alain Eschalier. Fatty acid amide hydrolase-dependent generation of antinociceptive drug metabolites acting on TRPV1 in the brain.
PloS one.
2013; 8(8):e70690. doi:
10.1371/journal.pone.0070690. [PMID: 23940628] - Lisa Alenmyr, Annkatrin Herrmann, Edward D Högestätt, Lennart Greiff, Peter M Zygmunt. TRPV1 and TRPA1 stimulation induces MUC5B secretion in the human nasal airway in vivo.
Clinical physiology and functional imaging.
2011 Nov; 31(6):435-44. doi:
10.1111/j.1475-097x.2011.01039.x. [PMID: 21981454] - Daniel Ursu, Kelly Knopp, Ruth E Beattie, Bin Liu, Emanuele Sher. Pungency of TRPV1 agonists is directly correlated with kinetics of receptor activation and lipophilicity.
European journal of pharmacology.
2010 Sep; 641(2-3):114-22. doi:
10.1016/j.ejphar.2010.05.029. [PMID: 20576527] - Zhi-Liang Chu, Chris Carroll, Ruoping Chen, Jean Alfonso, Veronica Gutierrez, Hongmei He, Annette Lucman, Charles Xing, Kristen Sebring, Jinyao Zhou, Brandee Wagner, David Unett, Robert M Jones, Dominic P Behan, James Leonard. N-oleoyldopamine enhances glucose homeostasis through the activation of GPR119.
Molecular endocrinology (Baltimore, Md.).
2010 Jan; 24(1):161-70. doi:
10.1210/me.2009-0239. [PMID: 19901198] - L Alenmyr, E D Högestätt, P M Zygmunt, L Greiff. TRPV1-mediated itch in seasonal allergic rhinitis.
Allergy.
2009 May; 64(5):807-10. doi:
10.1111/j.1398-9995.2009.01937.x. [PMID: 19220220] - Pouya Movahed, Vladimir Evilevitch, Tomas L G Andersson, Bo A G Jönsson, Per Wollmer, Peter M Zygmunt, Edward D Högestätt. Vascular effects of anandamide and N-acylvanillylamines in the human forearm and skin microcirculation.
British journal of pharmacology.
2005 Sep; 146(2):171-9. doi:
10.1038/sj.bjp.0706313. [PMID: 15997233] - J C Jerman, J Gray, S J Brough, L Ooi, D Owen, J B Davis, D Smart. Comparison of effects of anandamide at recombinant and endogenous rat vanilloid receptors.
British journal of anaesthesia.
2002 Dec; 89(6):882-7. doi:
10.1093/bja/aef281. [PMID: 12453933] - Chung-Ren Jan, Bang-Ping Jiann, Yih-Chau Lu, Hong-Tai Chang, Jong-Khing Huang. Effect of olvanil (N-vanillyl-cis-9-octadecenoamide) on cytosolic Ca2+ increase in renal tubular cells.
Life sciences.
2002 Nov; 71(26):3081-90. doi:
10.1016/s0024-3205(02)02174-4. [PMID: 12408875] - V Ralevic, D A Kendall, J C Jerman, D N Middlemiss, D Smart. Cannabinoid activation of recombinant and endogenous vanilloid receptors.
European journal of pharmacology.
2001 Jul; 424(3):211-9. doi:
10.1016/s0014-2999(01)01153-0. [PMID: 11672565] - D Smart, J C Jerman, M J Gunthorpe, S J Brough, J Ranson, W Cairns, P D Hayes, A D Randall, J B Davis. Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology.
European journal of pharmacology.
2001 Apr; 417(1-2):51-8. doi:
10.1016/s0014-2999(01)00901-3. [PMID: 11301059] - A Szallasi, V Di Marzo. New perspectives on enigmatic vanilloid receptors.
Trends in neurosciences.
2000 Oct; 23(10):491-7. doi:
10.1016/s0166-2236(00)01630-1. [PMID: 11006466] - M Beltramo, D Piomelli. Anandamide transport inhibition by the vanilloid agonist olvanil.
European journal of pharmacology.
1999 Jan; 364(1):75-8. doi:
10.1016/s0014-2999(98)00821-8. [PMID: 9920187] - G B Kasting, W R Francis, L A Bowman, G O Kinnett. Percutaneous absorption of vanilloids: in vivo and in vitro studies.
Journal of pharmaceutical sciences.
1997 Jan; 86(1):142-6. doi:
10.1021/js950484a. [PMID: 9002474] - W K Sietsema, E F Berman, R W Farmer, C S Maddin. The antinociceptive effect and pharmacokinetics of olvanil following oral and subcutaneous dosing in the mouse.
Life sciences.
1988; 43(17):1385-91. doi:
10.1016/0024-3205(88)90305-0. [PMID: 3185099]