2,4,3,5-tetramethoxystilbene (BioDeep_00000605773)

   


代谢物信息卡片


1-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-2,4-dimethoxy-benzene

化学式: C18H20O4 (300.13615200000004)
中文名称: 2,3,4,5-四甲氧基二苯乙烯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=CC(=C(C=C1)C=CC2=CC(=CC(=C2)OC)OC)OC
InChI: InChI=1S/C18H20O4/c1-19-15-8-7-14(18(12-15)22-4)6-5-13-9-16(20-2)11-17(10-13)21-3/h5-12H,1-4H3/b6-5+

描述信息

同义名列表

4 个代谢物同义名

2,4,3,5-tetramethoxystilbene; 2,3,4,5-Tetramethoxystilbene; 1-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-2,4-dimethoxy-benzene; TMS



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

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Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Annick D van den Brand, Judith Villevoye, Sandra M Nijmeijer, Martin van den Berg, Majorie B M van Duursen. Anti-tumor properties of methoxylated analogues of resveratrol in malignant MCF-7 but not in non-tumorigenic MCF-10A mammary epithelial cell lines. Toxicology. 2019 06; 422(?):35-43. doi: 10.1016/j.tox.2019.04.009. [PMID: 31004704]
  • Kirsty M Mair, Katie Y Harvey, Alasdair D Henry, Dianne Z Hillyard, Margaret Nilsen, Margaret R MacLean. Obesity alters oestrogen metabolism and contributes to pulmonary arterial hypertension. The European respiratory journal. 2019 06; 53(6):. doi: 10.1183/13993003.01524-2018. [PMID: 30923189]
  • Mireille Alhouayek, Sandra Gouveia-Figueira, Marie-Louise Hammarström, Christopher J Fowler. Involvement of CYP1B1 in interferon γ-induced alterations of epithelial barrier integrity. British journal of pharmacology. 2018 03; 175(6):877-890. doi: 10.1111/bph.14122. [PMID: 29232759]
  • Brett L Jennings, David E Montanez, Michael E May, Anne M Estes, Xiao R Fang, Fariborz A Yaghini, Alie Kanu, Kafait U Malik. Cytochrome P450 1B1 contributes to increased blood pressure and cardiovascular and renal dysfunction in spontaneously hypertensive rats. Cardiovascular drugs and therapy. 2014 Apr; 28(2):145-61. doi: 10.1007/s10557-014-6510-4. [PMID: 24477449]
  • Brett L Jennings, Larry J Anderson, Anne M Estes, Xiao R Fang, Chi Young Song, William B Campbell, Kafait U Malik. Involvement of cytochrome P-450 1B1 in renal dysfunction, injury, and inflammation associated with angiotensin II-induced hypertension in rats. American journal of physiology. Renal physiology. 2012 Feb; 302(4):F408-20. doi: 10.1152/ajprenal.00542.2011. [PMID: 22088434]
  • Seyhan Sahan-Firat, Brett L Jennings, Fariborz A Yaghini, Chi Young Song, Anne M Estes, Xiao R Fang, Nasreen Farjana, Amir I Khan, Kafait U Malik. 2,3',4,5'-Tetramethoxystilbene prevents deoxycorticosterone-salt-induced hypertension: contribution of cytochrome P-450 1B1. American journal of physiology. Heart and circulatory physiology. 2010 Dec; 299(6):H1891-901. doi: 10.1152/ajpheart.00655.2010. [PMID: 20852048]
  • Hai-Shu Lin, Qiu-Yi Choo, Paul C Ho. Quantification of oxyresveratrol analog trans-2,4,3',5'-tetramethoxystilbene in rat plasma by a rapid HPLC method: application in a pre-clinical pharmacokinetic study. Biomedical chromatography : BMC. 2010 Dec; 24(12):1373-8. doi: 10.1002/bmc.1454. [PMID: 21077256]
  • Kittisak Likhitwitayawuid, Acom Sornsute, Boonchoo Sritularak, Poonsakdi Ploypradith. Chemical transformations of oxyresveratrol (trans-2,4,3',5'-tetrahydroxystilbene) into a potent tyrosinase inhibitor and a strong cytotoxic agent. Bioorganic & medicinal chemistry letters. 2006 Nov; 16(21):5650-3. doi: 10.1016/j.bmcl.2006.08.018. [PMID: 16919455]
  • Young-Jin Chun, Sang-Kwang Lee, Mie Young Kim. Modulation of human cytochrome P450 1B1 expression by 2,4,3',5'-tetramethoxystilbene. Drug metabolism and disposition: the biological fate of chemicals. 2005 Dec; 33(12):1771-6. doi: 10.1124/dmd.105.006502. [PMID: 16120791]
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