PAz-PC (BioDeep_00000605541)
代谢物信息卡片
1-O-hexadecanoyl-2-O-(9-carboxyoctanoyl)-sn-glyceryl-3-phosphocholine
化学式: C33H64NO10P (665.4267614)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC(=O)O
InChI: InChI=1S/C33H64NO10P/c1-5-6-7-8-9-10-11-12-13-14-15-18-21-24-32(37)41-28-30(29-43-45(39,40)42-27-26-34(2,3)4)44-33(38)25-22-19-16-17-20-23-31(35)36/h30H,5-29H2,1-4H3,(H-,35,36,39,40)/t30-/m1/s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Tayana Mazin Tsubone, Helena Couto Junqueira, Maurício S Baptista, Rosangela Itri. Contrasting roles of oxidized lipids in modulating membrane microdomains.
Biochimica et biophysica acta. Biomembranes.
2019 03; 1861(3):660-669. doi:
10.1016/j.bbamem.2018.12.017. [PMID: 30605637] - Raffaela De Rosa, Francesco Spinozzi, Rosangela Itri. Hydroperoxide and carboxyl groups preferential location in oxidized biomembranes experimentally determined by small angle X-ray scattering: Implications in membrane structure.
Biochimica et biophysica acta. Biomembranes.
2018 11; 1860(11):2299-2307. doi:
10.1016/j.bbamem.2018.05.011. [PMID: 29852123] - Michael C Owen, Waldemar Kulig, Tomasz Rog, Ilpo Vattulainen, Birgit Strodel. Cholesterol Protects the Oxidized Lipid Bilayer from Water Injury: An All-Atom Molecular Dynamics Study.
The Journal of membrane biology.
2018 06; 251(3):521-534. doi:
10.1007/s00232-018-0028-9. [PMID: 29550877] - L H Moleiro, M Mell, R Bocanegra, I López-Montero, P Fouquet, Th Hellweg, J L Carrascosa, F Monroy. Permeability modes in fluctuating lipid membranes with DNA-translocating pores.
Advances in colloid and interface science.
2017 Sep; 247(?):543-554. doi:
10.1016/j.cis.2017.07.009. [PMID: 28735883] - Tiago Mendes Ferreira, Rohit Sood, Ruth Bärenwald, Göran Carlström, Daniel Topgaard, Kay Saalwächter, Paavo K J Kinnunen, O H Samuli Ollila. Acyl Chain Disorder and Azelaoyl Orientation in Lipid Membranes Containing Oxidized Lipids.
Langmuir : the ACS journal of surfaces and colloids.
2016 06; 32(25):6524-33. doi:
10.1021/acs.langmuir.6b00788. [PMID: 27260273] - Martin Lidman, Šárka Pokorná, Artur P G Dingeldein, Tobias Sparrman, Marcus Wallgren, Radek Šachl, Martin Hof, Gerhard Gröbner. The oxidized phospholipid PazePC promotes permeabilization of mitochondrial membranes by Bax.
Biochimica et biophysica acta.
2016 Jun; 1858(6):1288-97. doi:
10.1016/j.bbamem.2016.03.003. [PMID: 26947183] - Paavo K J Kinnunen, Yegor A Domanov, Juha-Pekka Mattila, Teemu Varis. Formation of lipid/peptide tubules by IAPP and temporin B on supported lipid membranes.
Soft matter.
2015 Dec; 11(47):9188-200. doi:
10.1039/b925228b. [PMID: 26575388] - Ali Makky, Motomu Tanaka. Impact of lipid oxidization on biophysical properties of model cell membranes.
The journal of physical chemistry. B.
2015 May; 119(18):5857-63. doi:
10.1021/jp512339m. [PMID: 25870900] - Cintia Kawai, Juliana C Ferreira, Mauricio S Baptista, Iseli L Nantes. Not only oxidation of cardiolipin affects the affinity of cytochrome C for lipid bilayers.
The journal of physical chemistry. B.
2014 Oct; 118(41):11863-72. doi:
10.1021/jp504518g. [PMID: 25247479] - Himanshu Khandelia, Bastien Loubet, Agnieszka Olzyńska, Piotr Jurkiewicz, Martin Hof. Pairing of cholesterol with oxidized phospholipid species in lipid bilayers.
Soft matter.
2014 Jan; 10(4):639-47. doi:
10.1039/c3sm52310a. [PMID: 24795978] - Marcus Wallgren, Lenka Beranova, Quoc Dat Pham, Khanh Linh, Martin Lidman, Jan Procek, Konrad Cyprych, Paavo K J Kinnunen, Martin Hof, Gerhard Gröbner. Impact of oxidized phospholipids on the structural and dynamic organization of phospholipid membranes: a combined DSC and solid state NMR study.
Faraday discussions.
2013; 161(?):499-513; discussion 563. doi:
10.1039/c2fd20089a. [PMID: 23805755] - Marcus Wallgren, Martin Lidman, Quoc Dat Pham, Konrad Cyprych, Gerhard Gröbner. The oxidized phospholipid PazePC modulates interactions between Bax and mitochondrial membranes.
Biochimica et biophysica acta.
2012 Nov; 1818(11):2718-24. doi:
10.1016/j.bbamem.2012.06.005. [PMID: 22705638] - Yongzhong Wang, Li Chen, Yunfei Ding, Weili Yan. Oxidized phospholipid based pH sensitive micelles for delivery of anthracyclines to resistant leukemia cells in vitro.
International journal of pharmaceutics.
2012 Jan; 422(1-2):409-17. doi:
10.1016/j.ijpharm.2011.10.029. [PMID: 22037443] - Rosalinda Sorrentino, Silvana Morello, Shuang Chen, Eduardo Bonavita, Aldo Pinto. The activation of liver X receptors inhibits toll-like receptor-9-induced foam cell formation.
Journal of cellular physiology.
2010 Apr; 223(1):158-67. doi:
10.1002/jcp.22022. [PMID: 20049870] - Abhay H Pande, Rajan K Tripathy. Preferential binding of apolipoprotein E derived peptides with oxidized phospholipid.
Biochemical and biophysical research communications.
2009 Feb; 380(1):71-5. doi:
10.1016/j.bbrc.2009.01.029. [PMID: 19159618] - Young Tag Ko, Amit Kale, William C Hartner, Brigitte Papahadjopoulos-Sternberg, Vladimir P Torchilin. Self-assembling micelle-like nanoparticles based on phospholipid-polyethyleneimine conjugates for systemic gene delivery.
Journal of controlled release : official journal of the Controlled Release Society.
2009 Jan; 133(2):132-8. doi:
10.1016/j.jconrel.2008.09.079. [PMID: 18929605] - Juha-Pekka Mattila, Karen Sabatini, Paavo K J Kinnunen. Interaction of cytochrome c with 1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine: evidence for acyl chain reversal.
Langmuir : the ACS journal of surfaces and colloids.
2008 Apr; 24(8):4157-60. doi:
10.1021/la703940s. [PMID: 18315024] - Jennifer L Kanter, Sirisha Narayana, Peggy P Ho, Ingrid Catz, Kenneth G Warren, Raymond A Sobel, Lawrence Steinman, William H Robinson. Lipid microarrays identify key mediators of autoimmune brain inflammation.
Nature medicine.
2006 Jan; 12(1):138-43. doi:
10.1038/nm1344. [PMID: 16341241]