Queuosine (BioDeep_00000605303)
代谢物信息卡片
化学式: C17H23N5O7 (409.1597408)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(C(C1NCC2=CN(C3=C2C(=O)NC(=N3)N)C4C(C(C(O4)CO)O)O)O)O
InChI: InChI=1S/C17H23N5O7/c18-17-20-14-10(15(28)21-17)6(3-19-7-1-2-8(24)11(7)25)4-22(14)16-13(27)12(26)9(5-23)29-16/h1-2,4,7-9,11-13,16,19,23-27H,3,5H2,(H3,18,20,21,28)/t7-,8-,9+,11+,12+,13+,16+/m0/s1
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:60193
- PubChem: 135540987
- Metlin: METLIN62373
- MeSH: Nucleoside Q
- CAS: 57072-36-3
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- James Jaryenneh, Joseph S Schoeniger, Catherine M Mageeney. Genome sequence and characterization of a novel Pseudomonas putida phage, MiCath.
Scientific reports.
2023 12; 13(1):21834. doi:
10.1038/s41598-023-48634-z. [PMID: 38071193] - Claire Fergus, Dominic Barnes, Mashael A Alqasem, Vincent P Kelly. The queuine micronutrient: charting a course from microbe to man.
Nutrients.
2015 Apr; 7(4):2897-929. doi:
10.3390/nu7042897. [PMID: 25884661] - Rémi Zallot, Céline Brochier-Armanet, Kirk W Gaston, Farhad Forouhar, Patrick A Limbach, John F Hunt, Valérie de Crécy-Lagard. Plant, animal, and fungal micronutrient queuosine is salvaged by members of the DUF2419 protein family.
ACS chemical biology.
2014 Aug; 9(8):1812-25. doi:
10.1021/cb500278k. [PMID: 24911101] - Marta Marchetti, Delphine Capela, Renaud Poincloux, Nacer Benmeradi, Marie-Christine Auriac, Aurélie Le Ru, Isabelle Maridonneau-Parini, Jacques Batut, Catherine Masson-Boivin. Queuosine biosynthesis is required for sinorhizobium meliloti-induced cytoskeletal modifications on HeLa Cells and symbiosis with Medicago truncatula.
PloS one.
2013; 8(2):e56043. doi:
10.1371/journal.pone.0056043. [PMID: 23409119] - Tatsiana Rakovich, Coilin Boland, Ilana Bernstein, Vimbai M Chikwana, Dirk Iwata-Reuyl, Vincent P Kelly. Queuosine deficiency in eukaryotes compromises tyrosine production through increased tetrahydrobiopterin oxidation.
The Journal of biological chemistry.
2011 Jun; 286(22):19354-63. doi:
10.1074/jbc.m111.219576. [PMID: 21487017] - Peng Chen, Gunilla Jäger, Bo Zheng. Transfer RNA modifications and genes for modifying enzymes in Arabidopsis thaliana.
BMC plant biology.
2010 Sep; 10(?):201. doi:
10.1186/1471-2229-10-201. [PMID: 20836892] - Jibin Sun, Xin Lu, Ursula Rinas, An Ping Zeng. Metabolic peculiarities of Aspergillus niger disclosed by comparative metabolic genomics.
Genome biology.
2007; 8(9):R182. doi:
10.1186/gb-2007-8-9-r182. [PMID: 17784953] - Jeremy Foster, Mehul Ganatra, Ibrahim Kamal, Jennifer Ware, Kira Makarova, Natalia Ivanova, Anamitra Bhattacharyya, Vinayak Kapatral, Sanjay Kumar, Janos Posfai, Tamas Vincze, Jessica Ingram, Laurie Moran, Alla Lapidus, Marina Omelchenko, Nikos Kyrpides, Elodie Ghedin, Shiliang Wang, Eugene Goltsman, Victor Joukov, Olga Ostrovskaya, Kiryl Tsukerman, Mikhail Mazur, Donald Comb, Eugene Koonin, Barton Slatko. The Wolbachia genome of Brugia malayi: endosymbiont evolution within a human pathogenic nematode.
PLoS biology.
2005 Apr; 3(4):e121. doi:
10.1371/journal.pbio.0030121. [PMID: 15780005] - R C Morris, M S Elliott. Queuosine modification of tRNA: a case for convergent evolution.
Molecular genetics and metabolism.
2001 Sep; 74(1-2):147-59. doi:
10.1006/mgme.2001.3216. [PMID: 11592812] - J R Katze, W T Beck, C S Cheng, J A McCloskey. Why is tumor tRNA hypomodified with respect to Q nucleoside?.
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.
1983; 84(?):146-59. doi:
10.1007/978-3-642-81947-6_10. [PMID: 6405458] - J R Katze, W R Farkas. A factor in serum and amniotic fluid is a substrate for the tRNA-modifying enzyme tRNA-guanine transferase.
Proceedings of the National Academy of Sciences of the United States of America.
1979 Jul; 76(7):3271-5. doi:
10.1073/pnas.76.7.3271. [PMID: 291001]