Tetrahydrogestrinone (BioDeep_00000604217)

   


代谢物信息卡片


(17a)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,9,11-trien-3-one

化学式: C21H28O2 (312.2089188)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCC1(CCC2C1(C=CC3=C4CCC(=O)C=C4CCC23)CC)O
InChI: InChI=1S/C21H28O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h9,11,13,18-19,23H,3-8,10,12H2,1-2H3/t18-,19+,20+,21+/m1/s1

描述信息

D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D045930 - Anabolic Agents
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D000728 - Androgens

同义名列表

3 个代谢物同义名

Tetrahydrogestrinone; (17a)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,9,11-trien-3-one; THG



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ruud J B Peters, Marcel C van Engelen, Manja E Touber, Costas Georgakopoulus, Michel W F Nielen. Searching for in silico predicted metabolites and designer modifications of (cortico)steroids in urine by high-resolution liquid chromatography/time-of-flight mass spectrometry. Rapid communications in mass spectrometry : RCM. 2009 Aug; 23(15):2329-37. doi: 10.1002/rcm.4153. [PMID: 19575408]
  • M Machnik, M Gerlach, M Kietzmann, F Niedorf, M Thevis, I Schenk, S Guddat, M Düe, W Schänzer. Detection and pharmacokinetics of tetrahydrogestrinone in horses. Journal of veterinary pharmacology and therapeutics. 2009 Apr; 32(2):197-202. doi: 10.1111/j.1365-2885.2008.01021.x. [PMID: 19290951]
  • Oliver Zierau, Sylvi Lehmann, Günter Vollmer, Willhelm Schänzer, Patrick Diel. Detection of anabolic steroid abuse using a yeast transactivation system. Steroids. 2008 Oct; 73(11):1143-7. doi: 10.1016/j.steroids.2008.04.015. [PMID: 18550137]
  • Marlice Aparecida Sípoli Marques, Henrique Marcelo Gualberto Pereira, Monica Costa Padilha, Francisco Radler de Aquino Neto. Analysis of synthetic 19-norsteroids trenbolone, tetrahydrogestrinone and gestrinone by gas chromatography-mass spectrometry. Journal of chromatography. A. 2007 May; 1150(1-2):215-25. doi: 10.1016/j.chroma.2006.08.032. [PMID: 16963059]
  • J-Pablo Salvador, Francisco Sanchez-Baeza, M-Pilar Marco. Preparation of antibodies for the designer steroid tetrahydrogestrinone and development of an enzyme-linked immunosorbent assay for human urine analysis. Analytical chemistry. 2007 May; 79(10):3734-40. doi: 10.1021/ac061757x. [PMID: 17441677]
  • M E Touber, M C van Engelen, C Georgakopoulus, J A van Rhijn, M W F Nielen. Multi-detection of corticosteroids in sports doping and veterinary control using high-resolution liquid chromatography/time-of-flight mass spectrometry. Analytica chimica acta. 2007 Mar; 586(1-2):137-46. doi: 10.1016/j.aca.2006.09.058. [PMID: 17386705]
  • Michel W F Nielen, Toine F H Bovee, Marcel C van Engelen, Paula Rutgers, Astrid R M Hamers, J Hans A van Rhijn, L Ron A P Hoogenboom. Urine testing for designer steroids by liquid chromatography with androgen bioassay detection and electrospray quadrupole time-of-flight mass spectrometry identification. Analytical chemistry. 2006 Jan; 78(2):424-31. doi: 10.1021/ac051317q. [PMID: 16408923]
  • Britt E Erickson. Detecting doping. Analytical chemistry. 2005 Jun; 77(11):211 A. doi: 10.1021/ac053395j. [PMID: 15957228]
  • Jean-François Lévesque, Erin Templeton, Laird Trimble, Carl Berthelette, Nathalie Chauret. Discovery, biosynthesis, and structure elucidation of metabolites of a doping agent and a direct analogue, tetrahydrogestrinone and gestrinone, using human hepatocytes. Analytical chemistry. 2005 May; 77(10):3164-72. doi: 10.1021/ac050150y. [PMID: 15889905]
  • Fernand Labrie, Van Luu-The, Ezequiel Calvo, Céline Martel, Julie Cloutier, Sylvain Gauthier, Pascal Belleau, Jean Morissette, Marie-Hélène Lévesque, Claude Labrie. Tetrahydrogestrinone induces a genomic signature typical of a potent anabolic steroid. The Journal of endocrinology. 2005 Feb; 184(2):427-33. doi: 10.1677/joe.1.05997. [PMID: 15684350]
  • Zoë J Foster, Jeffrey A Housner. Anabolic-androgenic steroids and testosterone precursors: ergogenic aids and sport. Current sports medicine reports. 2004 Aug; 3(4):234-41. doi: 10.1249/00149619-200408000-00011. [PMID: 15231229]
  • Steven Ashley. Doping by design. Scientific American. 2004 Feb; 290(2):22-3. doi: 10.1038/scientificamerican0204-22. [PMID: 14743721]
  • Don H Catlin, Michael H Sekera, Brian D Ahrens, Borislav Starcevic, Yu-Chen Chang, Caroline K Hatton. Tetrahydrogestrinone: discovery, synthesis, and detection in urine. Rapid communications in mass spectrometry : RCM. 2004; 18(12):1245-049. doi: 10.1002/rcm.1495. [PMID: 15174177]
  • Jonathan Knight. Drugs in sport: no dope. Nature. 2003 Nov; 426(6963):114-5. doi: 10.1038/426114a. [PMID: 14614473]