Galactosylhydroxylysine (BioDeep_00000603897)
代谢物信息卡片
Galactosylhydroxylysine
化学式: C12H24N2O8 (324.15325839999997)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(CC(C(=O)O)N)C(CN)OC1C(C(C(C(O1)CO)O)O)O
InChI: InChI=1S/C12H24N2O8/c13-3-5(1-2-6(14)11(19)20)21-12-10(18)9(17)8(16)7(4-15)22-12/h5-10,12,15-18H,1-4,13-14H2,(H,19,20)/t5?,6-,7+,8-,9-,10+,12+/m0/s1
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:37564
- PubChem: 123986
- Metlin: METLIN5576
- CAS: 32448-36-5
- RefMet: Galactosylhydroxylysine
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- F Pagani, C M Francucci, L Moro. Markers of bone turnover: biochemical and clinical perspectives.
Journal of endocrinological investigation.
2005; 28(10 Suppl):8-13. doi:
NULL. [PMID: 16550716] - S Ono, N Shimizu, T Imai, G P Rodriguez. Urinary collagen metabolite excretion in amyotrophic lateral sclerosis.
Muscle & nerve.
2001 Jun; 24(6):821-5. doi:
10.1002/mus.1075. [PMID: 11360267] - M Plebani, D Bernardi, M F Meneghetti, F Ujka, M Zaninotto. Biological variability in assessing the clinical value of biochemical markers of bone turnover.
Clinica chimica acta; international journal of clinical chemistry.
2000 Sep; 299(1-2):77-86. doi:
10.1016/s0009-8981(00)00285-0. [PMID: 10900294] - B Casetta, M Romanello, L Moro. A rapid and simple method for quantitation of urinary hydroxylysyl glycosides, indicators of collagen turnover, using liquid chromatography/tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2000; 14(23):2238-41. doi:
10.1002/1097-0231(20001215)14:23<2238::aid-rcm157>3.0.co;2-a. [PMID: 11114034] - V Lo Cascio, F Bertoldo, G Gambaro, E Gasperi, F Furlan, F Colapietro, C Lo Cascio, M Campagnola. Urinary galactosyl-hydroxylysine in postmenopausal osteoporotic women: A potential marker of bone fragility.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
1999 Aug; 14(8):1420-4. doi:
10.1359/jbmr.1999.14.8.1420. [PMID: 10457275] - S D Leigh, H S Ju, R Lundgard, G Y Daniloff, V Liu. Development of an immunoassay for urinary galactosylhydroxylysine.
Journal of immunological methods.
1998 Nov; 220(1-2):169-78. doi:
10.1016/s0022-1759(98)00159-8. [PMID: 9839938] - M Zaninotto, D Bernardi, F Ujka, P Bonato, M Plebani. A proposal for standardizing urine collections for bone resorption markers measurement.
Journal of clinical laboratory analysis.
1998; 12(3):145-9. doi:
10.1002/(sici)1098-2825(1998)12:3<145::aid-jcla3>3.0.co;2-8. [PMID: 9591700] - P Sirtori, C Sosio, R M Polo, R Tenni, A Rubinacci. A comparative study on biochemical markers of bone collagen breakdown in post-menopausal women.
Pharmacological research.
1997 Sep; 36(3):229-35. doi:
10.1006/phrs.1997.0220. [PMID: 9367668] - P Collet, D Uebelhart, L Vico, L Moro, D Hartmann, M Roth, C Alexandre. Effects of 1- and 6-month spaceflight on bone mass and biochemistry in two humans.
Bone.
1997 Jun; 20(6):547-51. doi:
10.1016/s8756-3282(97)00052-5. [PMID: 9177869] - E Casari, M Alfano, M Valente, G D Clarke, G Ferni, B Grazioli. Ovariectomy in the rat induces a rapid increase in the urinary excretion of hydroxylysine glycosides and non-reducible crosslink residues.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA.
1997; 7(6):539-43. doi:
10.1007/bf02652559. [PMID: 9604049] - A Rubinacci, P Divieti, R M Polo, M Zampino, G Resmini, R Tenni. Effect of an oral calcium load on urinary markers of collagen breakdown.
Journal of endocrinological investigation.
1996 Dec; 19(11):719-26. doi:
10.1007/bf03347874. [PMID: 9061504] - C Y Guo, W E Thomas, A W al-Dehaimi, A M Assiri, R Eastell. Longitudinal changes in bone mineral density and bone turnover in postmenopausal women with primary hyperparathyroidism.
The Journal of clinical endocrinology and metabolism.
1996 Oct; 81(10):3487-91. doi:
10.1210/jcem.81.10.8855790. [PMID: 8855790] - A Pecile, C Netti, V Sibilia, I Villa, G Calori, R Tenni, M Coluzzi, G L Moro, A Rubinacci. Comparison between urinary pyridinium cross-links and hydroxylysine glycosides in monitoring the effects of ovariectomy and 17 beta-estradiol replacement in aged rats.
The Journal of endocrinology.
1996 Sep; 150(3):383-90. doi:
10.1677/joe.0.1500383. [PMID: 8882157] - V Grazioli, M Alfano, A Stenico, E Casari. Urinary output of hydroxylysine glycosides and pyridinium cross-links in detecting rat bone collagen turnover rate.
FEBS letters.
1996 Jun; 388(2-3):134-8. doi:
10.1016/0014-5793(96)00505-4. [PMID: 8690072] - R Marabini, P Sirtori, R Chionna, L Barzizza, A Rubinacci. Galactosylhydroxylysine and pyridinium cross links in monitoring the bone response to hormone replacement therapy.
Journal of endocrinological investigation.
1996 Mar; 19(3):154-8. doi:
10.1007/bf03349858. [PMID: 8743280] - P Bettica, A K Taylor, J Talbot, L Moro, R Talamini, D J Baylink. Clinical performances of galactosyl hydroxylysine, pyridinoline, and deoxypyridinoline in postmenopausal osteoporosis.
The Journal of clinical endocrinology and metabolism.
1996 Feb; 81(2):542-6. doi:
10.1210/jcem.81.2.8636265. [PMID: 8636265] - M Romanello, K Noris Suarez, P Bettica, L Moro. Detection of pyridinium cross-links in human bile.
Calcified tissue international.
1995 Dec; 57(6):415-8. doi:
10.1007/bf00301942. [PMID: 8581871] - F Rauch, D Schnabel, M J Seibel, T Remer, A Stabrey, D Michalk, E Schönau. Urinary excretion of galactosyl-hydroxylysine is a marker of growth in children.
The Journal of clinical endocrinology and metabolism.
1995 Apr; 80(4):1295-300. doi:
10.1210/jcem.80.4.7714103. [PMID: 7714103] - M Michalsky, J J Stepan, H Wilczek, J Formankova, L Moro. Galactosyl hydroxylysine in assessment of Paget's bone disease.
Clinica chimica acta; international journal of clinical chemistry.
1995 Jan; 234(1-2):101-8. doi:
10.1016/0009-8981(94)05981-w. [PMID: 7758208] - H A Wollmann, E Schönau, W F Blum, F Meyer, K Kruse, M B Ranke. Dose-dependent responses in insulin-like growth factors, insulin-like growth factor-binding protein-3 and parameters of bone metabolism to growth hormone therapy in young adults with growth hormone deficiency.
Hormone research.
1995; 43(6):249-56. doi:
10.1159/000184302. [PMID: 7541769] - M Alfano, E Casari, A Stenico, M Murone, V Grazioli. Improved HPLC determination of urinary hydroxylysine glycosides to study turnover rate of bone in humans and rats.
Clinical chemistry.
1994 Nov; 40(11 Pt 1):2113-4. doi:
10.1093/clinchem/40.11.2113. [PMID: 7955391] - A K Taylor, S A Lueken, C Libanati, D J Baylink. Biochemical markers of bone turnover for the clinical assessment of bone metabolism.
Rheumatic diseases clinics of North America.
1994 Aug; 20(3):589-607. doi:
10.1016/s0889-857x(21)00351-3. [PMID: 7984780] - V LoCascio, V Braga, F Bertoldo, P Bettica, A F Pasini, L Stefani, L Moro. Effect of bisphosphonate therapy and parathyroidectomy on the urinary excretion of galactosylhydroxylysine in primary hyperparathyroidism.
Clinical endocrinology.
1994 Jul; 41(1):47-51. doi:
10.1111/j.1365-2265.1994.tb03783.x. [PMID: 8050131] - P Bettica, D J Baylink, L Moro. Galactosyl hydroxylysine and deoxypyridinoline: a methodological comparison.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies.
1993 Jul; 31(7):459-65. doi:
10.1515/cclm.1993.31.7.459. [PMID: 8399787] - V Grazioli, E Casari, M Murone, P A Bonini. High-performance liquid chromatographic method for measuring hydroxylysine glycosides and their ratio in urine as a possible marker of human bone collagen breakdown.
Journal of chromatography.
1993 May; 615(1):59-66. doi:
10.1016/0378-4347(93)80290-k. [PMID: 8340463] - L Moro, K Noris-Suarez, M Michalsky, M Romanello, B de Bernard. The glycosides of hydroxylysine are final products of collagen degradation in humans.
Biochimica et biophysica acta.
1993 Mar; 1156(3):288-90. doi:
10.1016/0304-4165(93)90044-9. [PMID: 8461318] - L Moro, C Gazzarrini, D Crivellari, E Galligioni, R Talamini, B de Bernard. Biochemical markers for detecting bone metastases in patients with breast cancer.
Clinical chemistry.
1993 Jan; 39(1):131-4. doi:
10.1093/clinchem/39.1.131. [PMID: 8419037] - P Bettica, L Moro, S P Robins, A K Taylor, J Talbot, F R Singer, D J Baylink. Bone-resorption markers galactosyl hydroxylysine, pyridinium crosslinks, and hydroxyproline compared.
Clinical chemistry.
1992 Nov; 38(11):2313-8. doi:
. [PMID: 1424129] - E Schönau, K Kruse, B de Bernard, L Moro. Further evidence of elevated bone resorption in Ullrich-Turner syndrome by measuring urinary galactosyl-hydroxylysine.
Acta paediatrica (Oslo, Norway : 1992).
1992 Aug; 81(8):633-4. doi:
10.1111/j.1651-2227.1992.tb12318.x. [PMID: 1392392] - G P Rodriquez, J Claus-Walker, G Reed. A study of osteoporosis as it relates to metabolic manifestations in edentulous women.
The Journal of oral implantology.
1992; 18(4):379-82. doi:
NULL. [PMID: 1298822] - P N Reddy, G D Raj, S C Dhar. Toxicological effects of an organophosphorus pesticide (dimethoate) on urinary collagen metabolites in normal and high protein diets fed female albino rats.
Life sciences.
1991; 49(18):1309-18. doi:
10.1016/0024-3205(91)90195-h. [PMID: 1921647] - L Moro, C Gazzarrini, C Modricky, L Rovis, B de Bernard, E Galligioni, D Crivellari, S Morassut, S Monfardini. High predictivity of galactosyl-hydroxylysine in urine as an indicator of bone metastases from breast cancer.
Clinical chemistry.
1990 May; 36(5):772-4. doi:
10.1093/clinchem/36.5.772. [PMID: 2337988] - G P Rodriguez, J Claus-Walker, M C Kent, H M Garza. Collagen metabolite excretion as a predictor of bone- and skin-related complications in spinal cord injury.
Archives of physical medicine and rehabilitation.
1989 Jun; 70(6):442-4. doi:
10.1016/0003-9993(89)90003-8. [PMID: 2730306] - L Moro, C Battista, C Modricky, L Rovis, B De Bernard, P Traldi, G Lubrano, F Marotti. High-performance liquid chromatographic preparation of galactosyl-hydroxylysine, a specific bone collagen marker.
Journal of chromatography.
1989 May; 490(2):285-92. doi:
10.1016/s0378-4347(00)82786-3. [PMID: 2768402] - L Moro, R S Pozzi Mucelli, C Gazzarrini, C Modricky, F Marotti, B de Bernard. Urinary beta-1-galactosyl-0-hydroxylysine (GH) as a marker of collagen turnover of bone.
Calcified tissue international.
1988 Feb; 42(2):87-90. doi:
10.1007/bf02556339. [PMID: 3127029] - L Moro, C Modricky, L Rovis, B de Bernard. Determination of galactosyl hydroxylysine in urine as a means for the identification of osteoporotic women.
Bone and mineral.
1988 Jan; 3(3):271-6. doi:
NULL. [PMID: 3207948] - C H Schröder, L A Monnens, H M van Lith-Zanders, J M Trijbels, J H Veerkamp. The urinary excretion of total hydroxylysine and its glycosides in normal persons, and in patients suffering from Alport's syndrome--contribution of the peptide-bound fraction.
Nephron.
1987; 47(4):253-7. doi:
10.1159/000184519. [PMID: 3696326] - C H Schröder, L A Monnens, H M van Lith-Zanders, J M Trijbels, J H Veerkamp, J P Langeveld. Urinary excretion of hydroxylysine and its glycosides in Alport's syndrome and several other glomerulopathies.
Nephron.
1986; 44(2):103-7. doi:
10.1159/000183975. [PMID: 3774073] - C H Schröder, J P Langeveld, B H van Raay-Selten, F J Trijbels, R de Graaf, J H Veerkamp, L A Monnens. Urinary excretion of hydroxylysine and its glycosides in normal persons of different ages--influence of maturation.
The International journal of pediatric nephrology.
1985 Oct; 6(4):239-44. doi:
. [PMID: 2419268] - A Jendryczko, M Drozdz, K Magner. Urinary excretions of hydroxylysylglycosides in rats with experimentally induced collagen-like syndrome.
Biomedica biochimica acta.
1985; 44(7-8):1133-7. doi:
. [PMID: 2417593] - L Moro, C Modricky, N Stagni, F Vittur, B de Bernard. High-performance liquid chromatographic analysis of urinary hydroxylysyl glycosides as indicators of collagen turnover.
The Analyst.
1984 Dec; 109(12):1621-2. doi:
10.1039/an9840901621. [PMID: 6532253] - G P Rodriguez, J Claus-Walker. Measurement of hydroxylysine glycosides in urine and its application to spinal cord injury.
Journal of chromatography.
1984 Jun; 308(?):65-73. doi:
10.1016/s0021-9673(01)87533-6. [PMID: 6746836] - Y Nagai, M Sato, M Sasaki. Effect of cadmium administration upon urinary excretion of hydroxylysine and hydroxyproline in the rat.
Toxicology and applied pharmacology.
1982 Apr; 63(2):188-93. doi:
10.1016/0041-008x(82)90040-0. [PMID: 7089969] - J P Segrest. Urinary metabolites of collagen.
Methods in enzymology.
1982; 82 Pt A(?):398-410. doi:
10.1016/0076-6879(82)82075-2. [PMID: 7078445] - Iu E Vel'tishchev, A A Ananenko, E I Daĭkhin, A I Klembovskiĭ, M S Ignatova. [Renal excretion of connective tissue metabolites and the state of the glomerular basement membranes in hereditary nephritis in children].
Pediatriia.
1981 Apr; ?(4):9-14. doi:
NULL. [PMID: 7255044] - E R Savolainen, M Kero, T Pihlajaniemi, K I Kivirikko. Deficiency of galactosylhydroxylysyl glucosyltransferase, an enzyme of collagen synthesis, in a family with dominant epidermolysis bullosa simplex.
The New England journal of medicine.
1981 Jan; 304(4):197-204. doi:
10.1056/nejm198101223040403. [PMID: 6449670] - D F Smith, D P Kosow, C Wu, G A Jamieson. Characterization of human platelet UDPglucose-collagen glucosyltransferase using a new rapid assay.
Biochimica et biophysica acta.
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