4E,15Z-Bilirubin IXa (BioDeep_00000603844)

   


代谢物信息卡片


4E,15Z-Bilirubin IXa

化学式: C33H36N4O6 (584.2634716)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C(NC(=C1CCC(=O)O)CC2=C(C(=C(N2)C=C3C(=C(C(=O)N3)C)C=C)C)CCC(=O)O)C=C4C(=C(C(=O)N4)C=C)C
InChI: InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13+,27-14-

描述信息

A linear tetrapyrrole, product of heme degradation. An isomer of bilirubin.
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同义名列表

1 个代谢物同义名

4E,15Z-Bilirubin IXa



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Yunchang Li, Israel Emiezi Agarry, Desheng Ding, Zsolt Zalán, Pimiao Huang, Tian Cai, Kewei Chen. Screening of dephytinization reaction of chlorophyll pigments with citrus acetone powder by UPLC-DAD-MS. Journal of food science. 2023 Jan; 88(1):147-160. doi: 10.1111/1750-3841.16411. [PMID: 36517982]
  • Min Wang, Li He, Bowei Chen, Yanwei Wang, Lishan Wang, Wei Zhou, Tianxu Zhang, Lesheng Cao, Peng Zhang, Linan Xie, Qingzhu Zhang. Transgenerationally Transmitted DNA Demethylation of a Spontaneous Epialleles Using CRISPR/dCas9-TET1cd Targeted Epigenetic Editing in Arabidopsis. International journal of molecular sciences. 2022 Sep; 23(18):. doi: 10.3390/ijms231810492. [PMID: 36142407]
  • Jana Knoppová, Roman Sobotka, Jianfeng Yu, Martina Bečková, Jan Pilný, Joko P Trinugroho, Ladislav Csefalvay, David Bína, Peter J Nixon, Josef Komenda. Assembly of D1/D2 complexes of photosystem II: Binding of pigments and a network of auxiliary proteins. Plant physiology. 2022 06; 189(2):790-804. doi: 10.1093/plphys/kiac045. [PMID: 35134246]
  • Yayun Peng, Yiyang Cong, Yuzhu Lei, Fanwen Sun, Menghan Xu, Jingzi Zhang, Lei Fang, Hao Hong, Ting Cai. Transforming Passive into Active: Multimodal Pheophytin-Based Carbon Dots Customize Protein Corona to Target Metastatic Breast Cancer. Advanced healthcare materials. 2022 04; 11(8):e2102270. doi: 10.1002/adhm.202102270. [PMID: 35032116]
  • Nobuyuki Takatani, Makoto Uenosono, Yuriko Hara, Hisanori Yamakawa, Yuichi Fujita, Tatsuo Omata. Chlorophyll and Pheophytin Dephytylating Enzymes Required for Efficient Repair of PSII in Synechococcus elongatus PCC 7942. Plant & cell physiology. 2022 Mar; 63(3):410-420. doi: 10.1093/pcp/pcac006. [PMID: 35024866]
  • Caihuang Xu, Qingjun Zhu, Jing-Hua Chen, Liangliang Shen, Xiaohan Yi, Zihui Huang, Wenda Wang, Min Chen, Tingyun Kuang, Jian-Ren Shen, Xing Zhang, Guangye Han. A unique photosystem I reaction center from a chlorophyll d-containing cyanobacterium Acaryochloris marina. Journal of integrative plant biology. 2021 Oct; 63(10):1740-1752. doi: 10.1111/jipb.13113. [PMID: 34002536]
  • Alexey A Zabelin, Anatoly Ya Shkuropatov. Pigment-modified reaction centers of Chloroflexus aurantiacus: chemical exchange of bacteriopheophytins with plant-type pheophytins. Photosynthesis research. 2021 Sep; 149(3):313-328. doi: 10.1007/s11120-021-00855-x. [PMID: 34138452]
  • Tim Schnabel, Elizabeth Sattely. Engineering Posttranslational Regulation of Glutamine Synthetase for Controllable Ammonia Production in the Plant Symbiont Azospirillum brasilense. Applied and environmental microbiology. 2021 06; 87(14):e0058221. doi: 10.1128/aem.00582-21. [PMID: 33962983]
  • Luis Apaza Ticona, Ginka Ilieva Lacheva, Andreea Madalina Serban, Ángel Rumbero Sánchez. Hydroalcoholic extract of Tagetes minuta L. inhibits inflammatory bowel disease through the activity of pheophytins on the NF-κB signalling pathway. Journal of ethnopharmacology. 2021 Mar; 268(?):113603. doi: 10.1016/j.jep.2020.113603. [PMID: 33242619]
  • F Goecke, J Noda, M Paliocha, H R Gislerød. Revision of Coelastrella (Scenedesmaceae, Chlorophyta) and first register of this green coccoid microalga for continental Norway. World journal of microbiology & biotechnology. 2020 Sep; 36(10):149. doi: 10.1007/s11274-020-02897-0. [PMID: 32914262]
  • Antonio Pérez-Gálvez, Isabel Viera, Itziar Benito, María Roca. HPLC-hrTOF-MS study of copper chlorophylls: Composition of food colorants and biochemistry after ingestion. Food chemistry. 2020 Aug; 321(?):126721. doi: 10.1016/j.foodchem.2020.126721. [PMID: 32251921]
  • Patricia Giampaoli, Francine Faia Fernandes, Armando Reis Tavares, Marisa Domingos, Poliana Cardoso-Gustavson. Fluorescence emission spectra of target chloroplast metabolites (flavonoids, carotenoids, lipofuscins, pheophytins) as biomarkers of air pollutants and seasonal tropical climate. Environmental science and pollution research international. 2020 Jul; 27(20):25363-25373. doi: 10.1007/s11356-020-08646-y. [PMID: 32347483]
  • Suellen Menezes-Silva, Narlize Silva Lira, Yuri Mangueira do Nascimento, Roseana Araújo Ramos Meireles, Celidarque da Silva Dias, Josean Fechine Tavares, Marcelo Sobral da Silva, George Emmanuel Cavalcanti de Miranda, José Maria Barbosa Filho, José Pinto de Siqueira-Junior. Modulation of drug resistance in Staphylococcus aureus by 132-hydroxy-(132-R/S)-pheophytin isolated from Sargassum polyceratium. Microbial pathogenesis. 2020 Apr; 141(?):104034. doi: 10.1016/j.micpath.2020.104034. [PMID: 32007619]
  • Mikhail A Grin, Sergei I Tikhonov, Albina S Petrova, Victor A Pogorilyy, Аlexey N Noev, Victor V Tatarskiy, Dmitry B Shpakovsky, Elena R Milaeva, Elena V Kalinina, Nikolai N Chernov, Аlexander А Shtil, Andrey F Mironov, Andrey D Kaprin, Elena V Filonenko. New Derivatives of Bacteriopurpurin with Thiolated Au (I) Complexes: Dual Darkand Light Activated Antitumor Potency. Anti-cancer agents in medicinal chemistry. 2020; 20(1):49-58. doi: 10.2174/1871520619666190801102617. [PMID: 31368879]
  • Dariusz Rydzyński, Agnieszka I Piotrowicz-Cieślak, Hanna Grajek, Janusz Wasilewski. Investigation of chlorophyll degradation by tetracycline. Chemosphere. 2019 Aug; 229(?):409-417. doi: 10.1016/j.chemosphere.2019.05.035. [PMID: 31082708]
  • Ana Carrasco Del Amor, Sara Freitas, Ralph Urbatzka, Olatz Fresnedo, Susana Cristobal. Application of Bioactive Thermal Proteome Profiling to Decipher the Mechanism of Action of the Lipid Lowering 132-Hydroxy-pheophytin Isolated from a Marine Cyanobacteria. Marine drugs. 2019 Jun; 17(6):. doi: 10.3390/md17060371. [PMID: 31234367]
  • Hamdoon A Mohammed, Mohsen S Al-Omar, Mahmoud Zaki El-Readi, Ahmad H Alhowail, Maha A Aldubayan, Ahmed A H Abdellatif. Formulation of Ethyl Cellulose Microparticles Incorporated Pheophytin A Isolated from Suaeda vermiculata for Antioxidant and Cytotoxic Activities. Molecules (Basel, Switzerland). 2019 Apr; 24(8):. doi: 10.3390/molecules24081501. [PMID: 30999569]
  • Ying Chen, Yousuke Shimoda, Makio Yokono, Hisashi Ito, Ayumi Tanaka. Mg-dechelatase is involved in the formation of photosystem II but not in chlorophyll degradation in Chlamydomonas reinhardtii. The Plant journal : for cell and molecular biology. 2019 03; 97(6):1022-1031. doi: 10.1111/tpj.14174. [PMID: 30471153]
  • Andreia F R Silva, Helena Abreu, Artur M S Silva, Susana M Cardoso. Effect of Oven-Drying on the Recovery of Valuable Compounds from Ulva rigida, Gracilaria sp. and Fucus vesiculosus. Marine drugs. 2019 Feb; 17(2):. doi: 10.3390/md17020090. [PMID: 30717174]
  • Rebecca L Hansen, Hongqing Guo, Yanhai Yin, Young Jin Lee. FERONIA mutation induces high levels of chloroplast-localized Arabidopsides which are involved in root growth. The Plant journal : for cell and molecular biology. 2019 01; 97(2):341-351. doi: 10.1111/tpj.14123. [PMID: 30300943]
  • Hong-Bo Xu, Tong-Hua Yang, Pei Xie, Shi-Jun Liu, Yan-Ni Liang, Yu Zhang, Zhong-Xing Song, Zhi-Shu Tang. Pheophytin analogues from the medicinal lichen Usnea diffracta. Natural product research. 2018 May; 32(9):1088-1094. doi: 10.1080/14786419.2017.1380019. [PMID: 29092623]
  • D G Semaan, J O Igoli, L Young, A I Gray, E G Rowan, E Marrero. In vitro anti-diabetic effect of flavonoids and pheophytins from Allophylus cominia Sw. on the glucose uptake assays by HepG2, L6, 3T3-L1 and fat accumulation in 3T3-L1 adipocytes. Journal of ethnopharmacology. 2018 Apr; 216(?):8-17. doi: 10.1016/j.jep.2018.01.014. [PMID: 29339110]
  • Yu-Ra Kang, Joon Park, Sung Keun Jung, Yoon Hyuk Chang. Synthesis, characterization, and functional properties of chlorophylls, pheophytins, and Zn-pheophytins. Food chemistry. 2018 Apr; 245(?):943-950. doi: 10.1016/j.foodchem.2017.11.079. [PMID: 29287463]
  • Petrina Kapewangolo, Martha Kandawa-Schulz, Debra Meyer. Anti-HIV Activity of Ocimum labiatum Extract and Isolated Pheophytin-a. Molecules (Basel, Switzerland). 2017 Nov; 22(11):. doi: 10.3390/molecules22111763. [PMID: 29113139]
  • D G Semaan, J O Igoli, L Young, E Marrero, A I Gray, E G Rowan. In vitro anti-diabetic activity of flavonoids and pheophytins from Allophylus cominia Sw . on PTP1B, DPPIV, alpha-glucosidase and alpha-amylase enzymes. Journal of ethnopharmacology. 2017 May; 203(?):39-46. doi: 10.1016/j.jep.2017.03.023. [PMID: 28341245]
  • Junyi Chen, Xiaoyu Zhu, Jun Ren, Kai Qiu, Zhongpeng Li, Zuokun Xie, Jiong Gao, Xin Zhou, Benke Kuai. Suppressor of Overexpression of CO 1 Negatively Regulates Dark-Induced Leaf Degreening and Senescence by Directly Repressing Pheophytinase and Other Senescence-Associated Genes in Arabidopsis. Plant physiology. 2017 03; 173(3):1881-1891. doi: 10.1104/pp.16.01457. [PMID: 28096189]
  • Otávio Augusto Chaves, Ana Paula de O Amorim, Larissa H E Castro, Carlos Mauricio R Sant'Anna, Márcia C C de Oliveira, Dari Cesarin-Sobrinho, José Carlos Netto-Ferreira, Aurélio B B Ferreira. Fluorescence and Docking Studies of the Interaction between Human Serum Albumin and Pheophytin. Molecules (Basel, Switzerland). 2015 Oct; 20(10):19526-39. doi: 10.3390/molecules201019526. [PMID: 26516829]
  • Djurre H de Jong, Nicoletta Liguori, Tom van den Berg, Clement Arnarez, Xavier Periole, Siewert J Marrink. Atomistic and Coarse Grain Topologies for the Cofactors Associated with the Photosystem II Core Complex. The journal of physical chemistry. B. 2015 Jun; 119(25):7791-803. doi: 10.1021/acs.jpcb.5b00809. [PMID: 26053327]
  • Mingchih Fang, Chia-Fen Tsai, Guan-Yan Wu, Su-Hsiang Tseng, Hwei-Fang Cheng, Ching-Hao Kuo, Che-Lun Hsu, Ya-Min Kao, Daniel Yang-Chih Shih, Yu-Mei Chiang. Identification and quantification of Cu-chlorophyll adulteration of edible oils. Food additives & contaminants. Part B, Surveillance. 2015; 8(3):157-62. doi: 10.1080/19393210.2015.1025861. [PMID: 26010536]
  • Miguel J Beltran-Garcia, James F White, Fernanda M Prado, Katia R Prieto, Lydia F Yamaguchi, Monica S Torres, Massuo J Kato, Marisa H G Medeiros, Paolo Di Mascio. Nitrogen acquisition in Agave tequilana from degradation of endophytic bacteria. Scientific reports. 2014 Nov; 4(?):6938. doi: 10.1038/srep06938. [PMID: 25374146]
  • Luzia Guyer, Silvia Schelbert Hofstetter, Bastien Christ, Bruno Silvestre Lira, Magdalena Rossi, Stefan Hörtensteiner. Different mechanisms are responsible for chlorophyll dephytylation during fruit ripening and leaf senescence in tomato. Plant physiology. 2014 Sep; 166(1):44-56. doi: 10.1104/pp.114.239541. [PMID: 25033826]
  • Fabrício E L Carvalho, Carolina W Ribeiro, Márcio O Martins, Aurenivia Bonifacio, Charley C Staats, Cláudia M B Andrade, João V Cerqueira, Márcia Margis-Pinheiro, Joaquim A G Silveira. Cytosolic APX knockdown rice plants sustain photosynthesis by regulation of protein expression related to photochemistry, Calvin cycle and photorespiration. Physiologia plantarum. 2014 Apr; 150(4):632-45. doi: 10.1111/ppl.12143. [PMID: 24329817]
  • Vokkaliga Thammegowda Harshavardhan, Le Van Son, Christiane Seiler, Astrid Junker, Kathleen Weigelt-Fischer, Christian Klukas, Thomas Altmann, Nese Sreenivasulu, Helmut Bäumlein, Markus Kuhlmann. AtRD22 and AtUSPL1, members of the plant-specific BURP domain family involved in Arabidopsis thaliana drought tolerance. PloS one. 2014; 9(10):e110065. doi: 10.1371/journal.pone.0110065. [PMID: 25333723]
  • Claudia I Victoria-Campos, José de Jesús Ornelas-Paz, Elhadi M Yahia, Mark L Failla. Effect of the interaction of heat-processing style and fat type on the micellarization of lipid-soluble pigments from green and red pungent peppers (Capsicum annuum). Journal of agricultural and food chemistry. 2013 Apr; 61(15):3642-53. doi: 10.1021/jf3054559. [PMID: 23517119]
  • Myoung-Yun Pyo, Bo-kyung Park, Jeong June Choi, Mihi Yang, Hyun Ok Yang, Jin Wook Cha, Jin-Cheol Kim, In Seon Kim, Hyang Burm Lee, Mirim Jin. Pheophytin a and chlorophyll a identified from environmentally friendly cultivation of green pepper enhance interleukin-2 and interferon-γ in Peyer's patches ex vivo. Biological & pharmaceutical bulletin. 2013; 36(11):1747-53. doi: 10.1248/bpb.b13-00302. [PMID: 24189419]
  • S A G Lambrechts, A van Dam, J de Vos, A van Weert, T Sijen, M C G Aalders. On the autofluorescence of fingermarks. Forensic science international. 2012 Oct; 222(1-3):89-93. doi: 10.1016/j.forsciint.2012.05.004. [PMID: 22658744]
  • Ramón Aparicio-Ruiz, María Roca, Beatriz Gandul-Rojas. Mathematical model to predict the formation of pyropheophytin a in virgin olive oil during storage. Journal of agricultural and food chemistry. 2012 Jul; 60(28):7040-9. doi: 10.1021/jf3010965. [PMID: 22708655]
  • Appian Subramoniam, Velikkakathu V Asha, Sadasivan Ajikumaran Nair, Sreejith P Sasidharan, Parameswaran K Sureshkumar, Krishnan Nair Rajendran, Devarajan Karunagaran, Krishnan Ramalingam. Chlorophyll revisited: anti-inflammatory activities of chlorophyll a and inhibition of expression of TNF-α gene by the same. Inflammation. 2012 Jun; 35(3):959-66. doi: 10.1007/s10753-011-9399-0. [PMID: 22038065]
  • Hui Li, Lina Li, Qiusheng Zheng, Chiaki Kuroda, Qi Wang. Phaeophytin analogues from Ligularia knorringiana. Molecules (Basel, Switzerland). 2012 May; 17(5):5219-24. doi: 10.3390/molecules17055219. [PMID: 22565475]
  • O V Pobeguts, T N Smolova, V V Klimov. Bicarbonate stabilizes isolated D1/D2/cytochrome b559 complex of photosystem 2 against thermoinactivation. Biochemistry. Biokhimiia. 2012 Feb; 77(2):171-9. doi: 10.1134/s0006297912020083. [PMID: 22348477]
  • Sándor Gonda, László Tóth, Gyöngyi Gyémánt, Mihály Braun, Tamás Emri, Gábor Vasas. Effect of high relative humidity on dried Plantago lanceolata L. leaves during long-term storage: effects on chemical composition, colour and microbiological quality. Phytochemical analysis : PCA. 2012 Jan; 23(1):88-93. doi: 10.1002/pca.1329. [PMID: 21618310]
  • Adriana P Gerola, Tayana M Tsubone, Amanda Santana, Hueder P M de Oliveira, Noboru Hioka, Wilker Caetano. Properties of chlorophyll and derivatives in homogeneous and microheterogeneous systems. The journal of physical chemistry. B. 2011 Jun; 115(22):7364-73. doi: 10.1021/jp201278b. [PMID: 21568354]
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  • Agustin M Büchert, Pedro M Civello, Gustavo A Martínez. Chlorophyllase versus pheophytinase as candidates for chlorophyll dephytilation during senescence of broccoli. Journal of plant physiology. 2011 Mar; 168(4):337-43. doi: 10.1016/j.jplph.2010.07.011. [PMID: 20727617]
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  • Angelo Cichelli, Gian Pietro Pertesana. High-performance liquid chromatographic analysis of chlorophylls, pheophytins and carotenoids in virgin olive oils: chemometric approach to variety classification. Journal of chromatography. A. 2004 Aug; 1046(1-2):141-6. doi: ". [PMID: 15387182]
  • Teresa Galeano Díaz, Isabel Durán Merás, Carlos Arturo Correa, Belén Roldán, María Isabel Rodríguez Cáceres. Simultaneous fluorometric determination of chlorophylls a and B and pheophytins a and B in olive oil by partial least-squares calibration. Journal of agricultural and food chemistry. 2003 Nov; 51(24):6934-40. doi: 10.1021/jf034456m. [PMID: 14611149]
  • Anatoli Ya Shkuropatov, Sieglinde Neerken, Hjalmar P Permentier, Rik de Wijn, Kristiane A Schmidt, Vladimir A Shuvalov, Thijs J Aartsma, Peter Gast, Arnold J Hoff. The effect of exchange of bacteriopheophytin a with plant pheophytin a on charge separation in Y(M210)W mutant reaction centers of Rhodobacter sphaeroides at low temperature. Biochimica et biophysica acta. 2003 Mar; 1557(1-3):1-12. doi: 10.1016/s0005-2728(02)00373-0. [PMID: 12615343]
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