Oxychlorpromazine (BioDeep_00000603106)
代谢物信息卡片
化学式: C17H19ClN2OS (334.0906554)
中文名称: 氧氯丙嗪
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN(C)CCCN1C2=CC=CC=C2S(=O)C3=C1C=C(C=C3)Cl
InChI: InChI=1S/C17H19ClN2OS/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)22(21)17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xufei Li, Yanying Yang, Kaowen Zhou. [Simultaneous determination of chlorpromazine and promethazine and their main metabolites by capillary electrophoresis with electrochemiluminescence].
Se pu = Chinese journal of chromatography.
2012 Sep; 30(9):938-42. doi:
10.3724/sp.j.1123.2012.04025. [PMID: 23285977] - Wakako Hikiji, Keiko Kudo, Shinji Sato, Yosuke Usumoto, Akiko Tsuji, Noriaki Ikeda. False negative result for amphetamines on the Triage Drug of Abuse panel? The cause of the unusual phenomenon with experimental analyses.
International journal of legal medicine.
2009 May; 123(3):247-52. doi:
10.1007/s00414-008-0304-9. [PMID: 19048267] - M Chetty, E Gouws, R Miller, S V Moodley. The use of a side effect as a qualitative indicator of plasma chlorpromazine levels.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology.
1999 Jan; 9(1-2):77-82. doi:
10.1016/s0924-977x(98)00005-4. [PMID: 10082231] - H Minami, T Nakahara, A Miyahara, Y Nakane. Prediction of drug responses in schizophrenia: a method using a test dose of chlorpromazine.
Psychiatry and clinical neurosciences.
1997 Aug; 51(4):217-22. doi:
10.1111/j.1440-1819.1997.tb02586.x. [PMID: 9316167] - P K Yeung, J W Hubbard, E D Korchinski, K K Midha. Radioimmunoassay for the N-oxide metabolite of chlorpromazine in human plasma and its application to a pharmacokinetic study in healthy humans.
Journal of pharmaceutical sciences.
1987 Oct; 76(10):803-8. doi:
10.1002/jps.2600761011. [PMID: 3430345] - K K Midha, J W Hubbard, J K Cooper, T Gurnsey, E M Hawes, G McKay, B S Chakraborty, P K Yeung. Therapeutic monitoring of chlorpromazine. IV: Comparison of a new high-performance liquid chromatographic method with radioimmunoassays for parent drug and some of its major metabolites.
Therapeutic drug monitoring.
1987 Sep; 9(3):358-65. doi:
. [PMID: 3672582] - E M Hawes, J W Hubbard, M Martin, G McKay, P K Yeung, K K Midha. Therapeutic monitoring of chlorpromazine. III: Minimal interconversion between chlorpromazine and metabolites in human blood.
Therapeutic drug monitoring.
1986; 8(1):37-41. doi:
. [PMID: 3961895] - J W Hubbard, J K Cooper, E M Hawes, D J Jenden, P R May, M Martin, G McKay, T Van Putten, K K Midha. Therapeutic monitoring of chlorpromazine I: Pitfalls in plasma analysis.
Therapeutic drug monitoring.
1985; 7(2):222-8. doi:
10.1097/00007691-198506000-00015. [PMID: 4024218] - G McKay, J K Cooper, E M Hawes, J W Hubbard, M Martin, K K Midha. Therapeutic monitoring of chlorpromazine II: Pitfalls in whole blood analysis.
Therapeutic drug monitoring.
1985; 7(4):472-7. doi:
10.1097/00007691-198512000-00020. [PMID: 4082244] - P K Yeung, J W Hubbard, J K Cooper, K K Midha. A study of the kinetics of chlorpromazine sulfoxide by a specific radioimmunoassay after a single oral dose of chlorpromazine in healthy volunteers.
The Journal of pharmacology and experimental therapeutics.
1983 Sep; 226(3):833-8. doi:
NULL. [PMID: 6887014] - T L FLANAGAN, T H LIN, W J NOVICK, I M RONDISH, C A BOCHER, E J VAN LOON. Spectrophotometric method for the determination of chlorpromazine and chlorpromazine sulphoxide in biological fluids.
Journal of medicinal and pharmaceutical chemistry.
1959 Jun; 1(?):263-73. doi:
10.1021/jm50004a005. [PMID: 13823366]