Menthokubanone (BioDeep_00000602821)

Main id: BioDeep_00000020083

PANOMIX_OTCML-2023

代谢物信息卡片

4,5,7-Trihydroxy-3,6,8-trimethoxyflavone

化学式: C18H16O8 (360.0845136)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1(O)=C(OC)C2OC(C3C=C(OC)C(O)=CC=3)=CC(=O)C=2C(O)=C1OC
InChI: InChI=1S/C18H16O8/c1-23-12-6-8(4-5-9(12)19)11-7-10(20)13-14(21)17(24-2)15(22)18(25-3)16(13)26-11/h4-7,19,21-22H,1-3H3

描述信息

同义名列表

3 个代谢物同义名

4,5,7-Trihydroxy-3,6,8-trimethoxyflavone; Menthokubanone; SUDACHITIN

数据库引用编号

6 个数据库交叉引用编号

ChEBI: CHEBI:175611
PubChem: 12443122
Metlin: METLIN49894
ChEMBL: CHEMBL479233
LipidMAPS: LMPK12111472
CAS: 4281-28-1

分类词条

Flavones and Flavonols [PK1211]

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

11 个相关的物种来源信息

1227627 - Artemisia klotzchiana: 10.1016/S0031-9422(00)81057-2
74351 - Biebersteinia orphanidis: 10.1016/S0031-9422(00)00355-1
558547 - Citrus deliciosa: 10.1248/CPB.28.717
171251 - Citrus medica: 10.1021/NP060217S
85571 - Citrus reticulata: 10.1248/CPB.28.717
558546 - Citrus sudachi: 10.1021/NP060217S
1770161 - Griffitharia pallescens: 10.1007/978-94-009-0975-5_12
199516 - Gutierrezia sarothrae: 10.1515/ZNC-1987-1-212
382522 - Helianthus strumosus: 10.1016/S0031-9422(00)80485-9
2741203 - Tetraneuris linearifolia: 10.1016/0031-9422(92)83709-8
76515 - Trichophorum cespitosum: 10.1016/0031-9422(80)85088-6

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Ricardo Satoshi Ota-Elliott, Yusuke Fukui, Yuting Bian, Zhihong Bian, Xinran Hu, Hongming Sun, Haibo Yu, Ryuta Morihara, Hiroyuki Ishiura, Toru Yamashita. Neuroprotective effect of, a flavonoid, sudachitin in mice stroke model. Brain research. 2024 03; 1827(?):148745. doi: 10.1016/j.brainres.2023.148745. [PMID: 38176520]
Kazuaki Mawatari, Nobuya Koike, Kazuanri Nohara, Marvin Wirianto, Takashi Uebanso, Takaaki Shimohata, Yasuhiro Shikishima, Hiroyuki Miura, Yoshitaka Nii, Mark J Burish, Kazuhiro Yagita, Akira Takahashi, Seung-Hee Yoo, Zheng Chen. The polymethoxyflavone Sudachitin modulates the circadian clock and improves liver physiology. Molecular nutrition & food research. 2023 Feb; ?(?):e2200270. doi: 10.1002/mnfr.202200270. [PMID: 36829302]
Gopalsamy Rajiv Gandhi, Alan Bruno Silva Vasconcelos, Ding-Tao Wu, Hua-Bin Li, Poovathumkal James Antony, Hang Li, Fang Geng, Ricardo Queiroz Gurgel, Narendra Narain, Ren-You Gan. Citrus Flavonoids as Promising Phytochemicals Targeting Diabetes and Related Complications: A Systematic Review of In Vitro and In Vivo Studies. Nutrients. 2020 Sep; 12(10):. doi: 10.3390/nu12102907. [PMID: 32977511]
Shogo Abe, Keizo Yuasa. Sudachitin, a polymethoxyflavone from Citrus sudachi, induces apoptosis via the regulation of MAPK pathways in human keratinocyte HaCaT cells. Biochemical and biophysical research communications. 2019 11; 519(2):344-350. doi: 10.1016/j.bbrc.2019.09.010. [PMID: 31514996]
Krisztina Végh, Eszter Riethmüller, Levente Hosszú, András Darcsi, Judit Müller, Ágnes Alberti, Anita Tóth, Szabolcs Béni, Árpád Könczöl, György Tibor Balogh, Ágnes Kéry. Three newly identified lipophilic flavonoids in Tanacetum parthenium supercritical fluid extract penetrating the Blood-Brain Barrier. Journal of pharmaceutical and biomedical analysis. 2018 Feb; 149(?):488-493. doi: 10.1016/j.jpba.2017.11.029. [PMID: 29182998]
Ki-Suk Kim, Dong Jin Lim, Hea Jung Yang, Eun-Kyeong Choi, Min Hee Shin, Kwang Seok Ahn, Sang Hoon Jung, Jae Young Um, Hee-Jae Jung, Jun Hee Lee, Seok-Geun Lee, Sung-Ki Jung, Hyeung-Jin Jang. The multi-targeted effects of Chrysanthemum herb extract against Escherichia coli O157:H7. Phytotherapy research : PTR. 2013 Sep; 27(9):1398-406. doi: 10.1002/ptr.4859. [PMID: 23255247]
Ayumi Uehara, Tsukasa Iwashina. Flavonoids from the Japanese monotypic genus, Nipponanthemum. Natural product communications. 2012 Aug; 7(8):1005-6. doi: . [PMID: 22978216]