trolox (BioDeep_00000600909)
代谢物信息卡片
3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid
化学式: C14H18O4 (250.1205)
中文名称: 奎诺二甲基丙烯酸酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C2=C(CCC(O2)(C)C(=O)O)C(=C1O)C)C
InChI: InChI=1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)
描述信息
D020011 - Protective Agents > D000975 - Antioxidants
同义名列表
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:82625
- PubChem: 40634
- Metlin: METLIN45333
- ChEMBL: CHEMBL153
- CAS: 56305-04-5
- CAS: 53188-07-1
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
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Journal of natural products.
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Journal of medicinal chemistry.
2022 07; 65(13):9174-9192. doi:
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Arhiv za higijenu rada i toksikologiju.
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Molecules (Basel, Switzerland).
2021 May; 26(11):. doi:
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Bioorganic & medicinal chemistry.
2021 04; 35(?):116074. doi:
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European journal of medicinal chemistry.
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European journal of medicinal chemistry.
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Molecules (Basel, Switzerland).
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Oxidative medicine and cellular longevity.
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Molecules (Basel, Switzerland).
2020 Nov; 25(22):. doi:
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ACS medicinal chemistry letters.
2020 Nov; 11(11):2232-2237. doi:
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The Journal of pharmacy and pharmacology.
2020 Nov; 72(11):1645-1656. doi:
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European journal of medicinal chemistry.
2020 Oct; 204(?):112620. doi:
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Anti-cancer drugs.
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Journal of pediatric urology.
2020 Aug; 16(4):465.e1-465.e8. doi:
10.1016/j.jpurol.2020.05.008. [PMID: 32595071] - Laura De Luca, Maria Paola Germanò, Antonella Fais, Francesca Pintus, Maria Rosa Buemi, Serena Vittorio, Salvatore Mirabile, Antonio Rapisarda, Rosaria Gitto. Discovery of a new potent inhibitor of mushroom tyrosinase (Agaricus bisporus) containing 4-(4-hydroxyphenyl)piperazin-1-yl moiety.
Bioorganic & medicinal chemistry.
2020 06; 28(11):115497. doi:
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Bioscience, biotechnology, and biochemistry.
2020 May; 84(5):1023-1029. doi:
10.1080/09168451.2020.1715782. [PMID: 31942834] - Yan-Gang Cao, Yan-Li Zhang, Meng-Nan Zeng, Man Qi, Ying-Jie Ren, Yan-Ling Liu, Xuan Zhao, Xiao-Ke Zheng, Wei-Sheng Feng. Renoprotective Mono- and Triterpenoids from the Fruit of Gardenia jasminoides.
Journal of natural products.
2020 04; 83(4):1118-1130. doi:
10.1021/acs.jnatprod.9b01119. [PMID: 32141747] - P S Besagil, S Çalapkorur, H Şahin. Determination of the relationship between total antioxidant capacity and dietary antioxidant intake in obese patients.
Nigerian journal of clinical practice.
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Free radical research.
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International journal of biological macromolecules.
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Journal of natural products.
2020 02; 83(2):185-193. doi:
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European journal of medicinal chemistry.
2020 Feb; 187(?):111958. doi:
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Molecules (Basel, Switzerland).
2019 Dec; 25(1):. doi:
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Molecules (Basel, Switzerland).
2019 Sep; 24(18):. doi:
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Chemical biology & drug design.
2019 09; 94(3):1680-1693. doi:
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Journal of the science of food and agriculture.
2019 Aug; 99(11):5157-5167. doi:
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Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2019 Aug; 219(?):358-366. doi:
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Biochimica et biophysica acta. Biomembranes.
2019 08; 1861(8):1489-1501. doi:
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Journal of medicinal chemistry.
2019 07; 62(13):6315-6329. doi:
10.1021/acs.jmedchem.9b00717. [PMID: 31246452] - Alexsandra Pereira Rodrigues, Gustavo Araujo Pereira, Pedro Henrique Ferreira Tomé, Henrique Silvano Arruda, Marcos Nogueira Eberlin, Glaucia Maria Pastore. Chemical Composition and Antioxidant Activity of Monguba (Pachira aquatica) Seeds.
Food research international (Ottawa, Ont.).
2019 07; 121(?):880-887. doi:
10.1016/j.foodres.2019.01.014. [PMID: 31108821] - Qiang Ren, Wen-Yu Zhao, Shao-Chun Shi, Feng-Ying Han, Ying-Ying Zhang, Qing-Bo Liu, Guo-Dong Yao, Bin Lin, Xiao-Xiao Huang, Shao-Jiang Song. Guaiane-Type Sesquiterpenoids from the Roots of Daphne genkwa and Evaluation of Their Neuroprotective Effects.
Journal of natural products.
2019 06; 82(6):1510-1517. doi:
10.1021/acs.jnatprod.8b01049. [PMID: 31150241] - Alexander V Samet, Oksana G Shevchenko, Vyacheslav V Rusak, Eduard M Chartov, Andrey B Myshlyavtsev, Daniil A Rusanov, Marina N Semenova, Victor V Semenov. Antioxidant Activity of Natural Allylpolyalkoxybenzene Plant Essential Oil Constituents.
Journal of natural products.
2019 Jun; ?(?):. doi:
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Chemical research in toxicology.
2019 06; 32(6):1165-1177. doi:
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Bioorganic & medicinal chemistry.
2019 04; 27(8):1658-1669. doi:
10.1016/j.bmc.2019.03.015. [PMID: 30858026] - Zafar Iqbal, Grant Morahan, Mahreen Arooj, Alexandre N Sobolev, Shahid Hameed. Synthesis of new arylsulfonylspiroimidazolidine-2',4'-diones and study of their effect on stimulation of insulin release from MIN6 cell line, inhibition of human aldose reductase, sorbitol accumulations in various tissues and oxidative stress.
European journal of medicinal chemistry.
2019 Apr; 168(?):154-175. doi:
10.1016/j.ejmech.2019.02.036. [PMID: 30818176] - Oluyomi Stephen Adeyemi, Rhoda Ananu Uloko, Oluwakemi Josephine Awakan, Anne Adebukola Adeyanju, David Adeiza Otohinoyi. The oral administration of silver nanoparticles activates the kynurenine pathway in rat brain independently of oxidative stress.
Chemico-biological interactions.
2019 Apr; 302(?):22-27. doi:
10.1016/j.cbi.2019.01.034. [PMID: 30707977] - Xue-Gui Liu, Yu-Qiu Sun, Jun Bian, Ting Han, Dan-Dan Yue, Dan-Qi Li, Pin-Yi Gao. Neuroprotective effects of triterpenoid saponins from Medicago sativa L. against H2O2-induced oxidative stress in SH-SY5Y cells.
Bioorganic chemistry.
2019 03; 83(?):468-476. doi:
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Journal of medicinal chemistry.
2019 02; 62(4):2184-2201. doi:
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ACS medicinal chemistry letters.
2019 Jan; 10(1):98-104. doi:
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Cellular and molecular neurobiology.
2018 Nov; 38(8):1505-1516. doi:
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Menopause (New York, N.Y.).
2018 11; 25(11):1214-1223. doi:
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Molecules (Basel, Switzerland).
2018 Sep; 23(10):. doi:
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Journal of natural products.
2018 08; 81(8):1819-1828. doi:
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Journal of natural products.
2018 08; 81(8):1693-1700. doi:
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Zygote (Cambridge, England).
2018 Aug; 26(4):333-335. doi:
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Plant foods for human nutrition (Dordrecht, Netherlands).
2018 Jun; 73(2):122-129. doi:
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Chemico-biological interactions.
2018 Jun; 289(?):119-128. doi:
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Talanta.
2018 May; 182(?):55-61. doi:
10.1016/j.talanta.2018.01.047. [PMID: 29501192] - Barbara Tóth, Judit Hohmann, Andrea Vasas. Phenanthrenes: A Promising Group of Plant Secondary Metabolites.
Journal of natural products.
2018 03; 81(3):661-678. doi:
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Food chemistry.
2018 Mar; 243(?):428-434. doi:
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Chemistry and physics of lipids.
2018 03; 211(?):44-51. doi:
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Journal of natural products.
2018 02; 81(2):227-235. doi:
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International journal of molecular sciences.
2018 Feb; 19(2):. doi:
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2018 Jan; 111(?):503-510. doi:
10.1016/j.fct.2017.12.002. [PMID: 29217270] - Siriporn Okonogi, Adchareeya Kaewpinta, Taepin Junmahasathien, Songwut Yotsawimonwat. Effect of rice variety and modification on antioxidant and anti-inflammatory activities.
Drug discoveries & therapeutics.
2018 ; 12(4):206-213. doi:
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Food chemistry.
2017 Dec; 237(?):989-996. doi:
10.1016/j.foodchem.2017.06.034. [PMID: 28764097] - Yuma Ishida, Yuka Okamoto, Yuta Matsuoka, Arisa Tada, Jindaporn Janprasit, Mayumi Yamato, Noppawan Phumala Morales, Ken-Ichi Yamada. Detection and inhibition of lipid-derived radicals in low-density lipoprotein.
Free radical biology & medicine.
2017 12; 113(?):487-493. doi:
10.1016/j.freeradbiomed.2017.10.388. [PMID: 29107744] - Kamila Czubak, Adam Antosik, Natalia Cichon, Halina Malgorzata Zbikowska. Vitamin C and Trolox decrease oxidative stress and hemolysis in cold-stored human red blood cells.
Redox report : communications in free radical research.
2017 Nov; 22(6):445-450. doi:
10.1080/13510002.2017.1289314. [PMID: 28277068] - Małgorzata Sztanke, Krzysztof Sztanke. Biologically important hydrazide-containing fused azaisocytosines as antioxidant agents.
Redox report : communications in free radical research.
2017 Nov; 22(6):572-581. doi:
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Bioorganic & medicinal chemistry letters.
2017 11; 27(21):4800-4804. doi:
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Food research international (Ottawa, Ont.).
2017 11; 101(?):173-179. doi:
10.1016/j.foodres.2017.09.007. [PMID: 28941681] - Gabriele Rocchetti, Luigi Lucini, Giulia Chiodelli, Gianluca Giuberti, Domenico Montesano, Francesco Masoero, Marco Trevisan. Impact of boiling on free and bound phenolic profile and antioxidant activity of commercial gluten-free pasta.
Food research international (Ottawa, Ont.).
2017 10; 100(Pt 2):69-77. doi:
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Scientific reports.
2017 09; 7(1):11733. doi:
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Free radical biology & medicine.
2017 09; 110(?):92-101. doi:
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European journal of medicinal chemistry.
2017 Jun; 133(?):379-402. doi:
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Bioorganic & medicinal chemistry letters.
2017 06; 27(11):2302-2307. doi:
10.1016/j.bmcl.2017.04.044. [PMID: 28434766] - Jong-Lyel Roh, Eun Hye Kim, Hyejin Jang, Daiha Shin. Nrf2 inhibition reverses the resistance of cisplatin-resistant head and neck cancer cells to artesunate-induced ferroptosis.
Redox biology.
2017 04; 11(?):254-262. doi:
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Food chemistry.
2017 Mar; 218(?):305-312. doi:
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Bioorganic & medicinal chemistry letters.
2017 02; 27(3):460-465. doi:
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European journal of medicinal chemistry.
2017 Jan; 126(?):762-775. doi:
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Medicinal chemistry (Shariqah (United Arab Emirates)).
2017; 13(3):214-225. doi:
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Clinical and experimental hypertension (New York, N.Y. : 1993).
2017; 39(4):344-349. doi:
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Journal of natural products.
2016 Dec; 79(12):3065-3071. doi:
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Journal of food science.
2016 Dec; 81(12):C2923-C2931. doi:
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European journal of medicinal chemistry.
2016 Nov; 124(?):622-636. doi:
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Bioorganic & medicinal chemistry letters.
2016 11; 26(22):5501-5506. doi:
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Bioorganic & medicinal chemistry letters.
2016 11; 26(21):5218-5221. doi:
10.1016/j.bmcl.2016.09.060. [PMID: 27712938] - Elodie Lohou, N André Sasaki, Agnès Boullier, Pascal Sonnet. Multifunctional diamine AGE/ALE inhibitors with potential therapeutical properties against Alzheimer's disease.
European journal of medicinal chemistry.
2016 Oct; 122(?):702-722. doi:
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European journal of medicinal chemistry.
2016 Oct; 121(?):331-337. doi:
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Molecular medicine (Cambridge, Mass.).
2016 Oct; 22(?):548-559. doi:
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Food & function.
2016 Aug; 7(8):3590-8. doi:
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Journal of food science.
2016 Aug; 81(8):C1914-20. doi:
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Journal of natural products.
2016 07; 79(7):1808-14. doi:
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Carbohydrate polymers.
2016 Jun; 144(?):149-58. doi:
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Journal of the science of food and agriculture.
2016 Jun; 96(8):2641-9. doi:
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Journal of food science.
2016 May; 81(5):C1055-61. doi:
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Cryobiology.
2016 Apr; 72(2):112-8. doi:
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Bioorganic & medicinal chemistry letters.
2016 Mar; 26(6):1594-1598. doi:
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Molecular nutrition & food research.
2016 Mar; 60(3):487-94. doi:
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Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2016 Mar; 181-182(?):47-54. doi:
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Plant & cell physiology.
2016 Mar; 57(3):642-53. doi:
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Journal of natural products.
2016 Feb; 79(2):395-405. doi:
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American journal of physiology. Endocrinology and metabolism.
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