dibekacin (BioDeep_00000600344)

   

Chemicals and Drugs Antibiotics


代谢物信息卡片


dibekacin

化学式: C18H37N5O8 (451.2642002)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CC(C(OC1CN)OC2C(CC(C(C2O)OC3C(C(C(C(O3)CO)O)N)O)N)N)N
InChI: InChI=1S/C18H37N5O8/c19-4-6-1-2-7(20)17(28-6)30-15-8(21)3-9(22)16(14(15)27)31-18-13(26)11(23)12(25)10(5-24)29-18/h6-18,24-27H,1-5,19-23H2/t6-,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1

描述信息

J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01G - Aminoglycoside antibacterials
A kanamycin that is kanamycin B lacking the 3- and 4-hydroxy groups on the 2,6-diaminosugar ring.
S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AA - Antibiotics
C784 - Protein Synthesis Inhibitor > C2363 - Aminoglycoside Antibiotic
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C254 - Anti-Infective Agent > C258 - Antibiotic

同义名列表

1 个代谢物同义名

dibekacin



数据库引用编号

8 个数据库交叉引用编号

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代谢反应

0 个相关的代谢反应过程信息。

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  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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文献列表

  • Elizabeth A Lakota, Nobuo Sato, Tomokazu Koresawa, Kenichiro Kondo, Sujata M Bhavnani, Paul G Ambrose, Christopher M Rubino. Population Pharmacokinetic Analyses for Arbekacin after Administration of ME1100 Inhalation Solution. Antimicrobial agents and chemotherapy. 2019 08; 63(8):. doi: 10.1128/aac.00267-19. [PMID: 31182524]
  • Yoko Hirai, Kazunori Maebashi, Hideki Fushimi, Yukiko Hiraiwa, Shoichi Murakami, Takayuki Usui, Yoshihisa Akiyama, Nobuto Minowa, Daishiro Ikeda. In vitro and in vivo antimicrobial activity of TS2037, a novel aminoglycoside antibiotic. The Journal of antibiotics. 2018 03; 71(3):363-371. doi: 10.1038/s41429-017-0002-2. [PMID: 29348522]
  • Kohei Uechi, Tatsuya Tada, Kayo Shimada, Isamu Nakasone, Tetsu Sonozaki, Teruo Kirikae, Jiro Fujita. Emergence of ArmA, a 16S rRNA methylase in highly aminoglycoside-resistant clinical isolates of Klebsiella pneumoniae and Klebsiella oxytoca in Okinawa, Japan. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2018 Jan; 24(1):68-70. doi: 10.1016/j.jiac.2017.09.006. [PMID: 29066218]
  • Norihito Kaku, Yoshitomo Morinaga, Kazuaki Takeda, Kosuke Kosai, Naoki Uno, Hiroo Hasegawa, Taiga Miyazaki, Koichi Izumikawa, Hiroshi Mukae, Katsunori Yanagihara. Efficacy and pharmacokinetics of ME1100, a novel optimized formulation of arbekacin for inhalation, compared with amikacin in a murine model of ventilator-associated pneumonia caused by Pseudomonas aeruginosa. The Journal of antimicrobial chemotherapy. 2017 04; 72(4):1123-1128. doi: 10.1093/jac/dkw517. [PMID: 27999047]
  • Mao Hagihara, Hideo Kato, Yukihiro Hamada, Jun Hirai, Daisuke Sakanashi, Hiroyuki Suematsu, Naoya Nishiyama, Yusuke Koizumi, Yuka Yamagishi, Katsuhiko Matsuura, Hiroshige Mikamo. Population pharmacokinetics of arbekacin in different infectious disease settings and evaluation of dosing regimens. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2016 Jul; 22(7):436-43. doi: 10.1016/j.jiac.2016.03.008. [PMID: 27260679]
  • Yohei Funatsu, Naoki Hasegawa, Hiroshi Fujiwara, Ho Namkoong, Takahiro Asami, Sadatomo Tasaka, Yoshifumi Kimizuka, Hirofumi Kamata, Makoto Ishii, Osamu Iketani, Haruhiko Ogata, Satoshi Iwata, Tomoko Betsuyaku. Pharmacokinetics of arbekacin in bronchial epithelial lining fluid of healthy volunteers. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2014 Oct; 20(10):607-11. doi: 10.1016/j.jiac.2014.05.007. [PMID: 24973909]
  • Kenji Okada, Toshimi Kimura, Hiroshige Mikamo, Kei Kasahara, Masafumi Seki, Shunji Takakura, Issei Tokimatsu, Norio Ohmagari, Yoshiko Takahashi, Kazuaki Matsumoto, Masahiro Igarashi, Masahiro Kobayashi, Yukihiro Hamada, Takahiro Mochizuki, Masao Kimura, Yoshifumi Nishi, Yusuke Tanigawara, Yoshio Takesue. Clinical practice guidelines for therapeutic drug monitoring of arbekacin: a consensus review of the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2014 Jan; 20(1):1-5. doi: 10.1016/j.jiac.2013.08.008. [PMID: 24486168]
  • Sangeetha Rajenderan, Veeraraghavan Balaji, Shalini Anandan, Rani Diana Sahni, Giannoula S Tansarli, Matthew E Falagas. Determination of MIC distribution of arbekacin, cefminox, fosfomycin, biapenem and other antibiotics against gram-negative clinical isolates in South India: a prospective study. PloS one. 2014; 9(7):e103253. doi: 10.1371/journal.pone.0103253. [PMID: 25068396]
  • Keisuke Sunakawa, Seiji Hori. [Safety and pharmacokinetics of 400 and 600 mg arbekacin sulfate to healthy male volunteers]. The Japanese journal of antibiotics. 2013 Apr; 66(2):97-109. doi: NULL. [PMID: 23951728]
  • Autumn R Breaud, Claudia L Henemyre-Harris, Sabitha Schools, Nkechinyere Emezienna, William Clarke. Rapid quantification of the aminoglycoside arbekacin in serum using high performance liquid chromatography-tandem mass spectrometry. Clinica chimica acta; international journal of clinical chemistry. 2013 Mar; 418(?):102-6. doi: 10.1016/j.cca.2013.01.004. [PMID: 23333924]
  • Tetsuya Matsumoto, Hideaki Hanaki, Toshimi Kimura, Manabu Nemoto, Masaaki Higashihara, Hiroyuki Yokota, Shigeto Oda, Nobu Akiyama, Naoki Miyao, Minoru Yoshida, Tetsuo Yukioka, Kazui Soma, Kazuma Ohyashiki, Yukio Suzuki, Takao Arai, Keiichi Ikegami, Toshio Ichiwata, Yoshihito Otsuka, Masahiro Kobayashi, Kyoichi Totsuka, Keisuke Sunakawa. Clinical efficacy and safety of arbekacin sulfate in patients with MRSA sepsis or pneumonia: a multi-institutional study. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2013 Feb; 19(1):128-37. doi: 10.1007/s10156-012-0519-z. [PMID: 23263188]
  • Yukihiro Hamada, Kazuyoshi Tamura, Ikumi Koyama, Megumi Seki, Kazuo Yago, Keisuke Sunakawa, Masakazu Kuroyama. Evaluation of arbekacin anti-MRSA agents for adult in Japan. The Japanese journal of antibiotics. 2012 Aug; 65(4):221-34. doi: NULL. [PMID: 23259253]
  • Masahiko Hayashi, Kazuya Ooi, Satoko Yamada, Hiromi Wakabayashi, Takao Imanishi, Makoto Kondo, Masami Nishii, Kazuro Ikawa, Norifumi Morikawa. [Arbekacin sulfate concentrations in peripheral lymph and in serum after intravenous injection: report of four cases]. The Japanese journal of antibiotics. 2012 Jun; 65(3):207-15. doi: NULL. [PMID: 23173295]
  • Yoshihiro Yamamoto, Koichi Izumikawa, Koji Hashiguchi, Yuichi Fukuda, Tsutomu Kobayashi, Akira Kondo, Yuichi Inoue, Yoshitomo Morinaga, Shigeki Nakamura, Yoshifumi Imamura, Taiga Miyazaki, Hiroshi Kakeya, Katsunori Yanagihara, Shigeru Kohno. The efficacy and safety of high-dose arbekacin sulfate therapy (once-daily treatment) in patients with MRSA infection. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2012 Apr; 18(2):241-6. doi: 10.1007/s10156-012-0397-4. [PMID: 22398881]
  • Daisuke Kinoshita. [Evaluation of once a day of arbekacin administration to neonates as a new object of peak concentration]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 2010 Nov; 84(6):727-33. doi: 10.11150/kansenshogakuzasshi.84.727. [PMID: 21226325]
  • Andrew Prayle, Alan Watson, Heather Fortnum, Alan Smyth. Side effects of aminoglycosides on the kidney, ear and balance in cystic fibrosis. Thorax. 2010 Jul; 65(7):654-8. doi: 10.1136/thx.2009.131532. [PMID: 20627927]
  • Kazuro Ikawa, Norifumi Morikawa, Hidemichi Suyama, Kayo Ikeda, Takao Yamanoue. Pharmacokinetics and pharmacodynamics of once-daily arbekacin during continuous venovenous hemodiafiltration in critically ill patients. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2009 Dec; 15(6):420-3. doi: 10.1007/s10156-009-0717-5. [PMID: 20012736]
  • Roberto Cabrera, Joaquím Ruiz, Javier Sánchez-Céspedes, Pilar Goñi, Rafael Gómez-Lus, M Teresa Jiménez de Anta, Joaquím Gascón, Jordi Vila. Characterization of the enzyme aac(3)-Id in a clinical isolate of Salmonella enterica serovar Haifa causing traveler's diarrhea. Enfermedades infecciosas y microbiologia clinica. 2009 Oct; 27(8):453-6. doi: 10.1016/j.eimc.2008.11.016. [PMID: 19403206]
  • Kenji Fujii, Junya Nagai, Takeshi Sawada, Ryoko Yumoto, Mikihisa Takano. Effect of PEGylation of N-WASP181-200 on the inhibitory potency for renal aminoglycoside accumulation. Bioconjugate chemistry. 2009 Aug; 20(8):1553-8. doi: 10.1021/bc900094g. [PMID: 19572636]
  • N Fukuoka, M Aibiki. Recommended dose of arbekacin, an aminoglycoside against methicillin-resistant Staphylococcus aureus, does not achieve desired serum concentration in critically ill patients with lowered creatinine clearance. Journal of clinical pharmacy and therapeutics. 2008 Oct; 33(5):521-7. doi: 10.1111/j.1365-2710.2008.00947.x. [PMID: 18834367]
  • R Scott Obach, Franco Lombardo, Nigel J Waters. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals. 2008 Jul; 36(7):1385-405. doi: 10.1124/dmd.108.020479. [PMID: 18426954]
  • Jong Hyun Kim, Hyon-Oh Lah, Dong-Seok Yim. Population pharmacokinetics of arbekacin in burn patients. European journal of clinical pharmacology. 2008 Jun; 64(6):599-603. doi: 10.1007/s00228-008-0470-1. [PMID: 18320181]
  • T Otsuka, A Tanaka, K Suemaru, T Inoue, T Nishimiya, M Murase, H Araki. Evaluation of the clinical application of cystatin C, a new marker of the glomerular filtration rate, for the initial dose-setting of arbekacin. Journal of clinical pharmacy and therapeutics. 2008 Jun; 33(3):227-35. doi: 10.1111/j.1365-2710.2008.00905.x. [PMID: 18452409]
  • Sachiko Murakami, Junya Nagai, Kenji Fujii, Ryoko Yumoto, Mikihisa Takano. Influences of dosage regimen and co-administration of low-molecular weight proteins and basic peptides on renal accumulation of arbekacin in mice. The Journal of antimicrobial chemotherapy. 2008 Mar; 61(3):658-64. doi: 10.1093/jac/dkm512. [PMID: 18192282]
  • Shigeo Yamamura, Keiko Kawada, Rieko Takehira, Kenji Nishizawa, Shirou Katayama, Masaaki Hirano, Yasunori Momose. Prediction of aminoglycoside response against methicillin-resistant Staphylococcus aureus infection in burn patients by artificial neural network modeling. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2008 Jan; 62(1):53-8. doi: 10.1016/j.biopha.2007.11.004. [PMID: 18083323]
  • Hiroyuki Hayashi, Takashi Matsuzaki, Akio Saito, Takahiko Aoyama, Yoshiaki Matsumoto. [Analysis of factors in selecting anti-methicillin-resistant Staphylococcus aureus drugs by doctors]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2008 Jan; 128(1):81-7. doi: 10.1248/yakushi.128.81. [PMID: 18176058]
  • Hideya Kokubun, Toshimi Kimura, Kazuo Yago. [Appropriate usage of antibiotics by therapeutic drug monitoring]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2007 Jun; 127(6):925-9. doi: 10.1248/yakushi.127.925. [PMID: 17541241]
  • Yusuke Tanigawara, Reiko Sato, Kunihiko Morita, Mitsuo Kaku, Naoki Aikawa, Kihachiro Shimizu. Population pharmacokinetics of Arbekacin in patients infected with methicillin-resistant Staphylococcus aureus. Antimicrobial agents and chemotherapy. 2006 Nov; 50(11):3754-62. doi: 10.1128/aac.00420-05. [PMID: 17065621]
  • Reiko Sato, Yusuke Tanigawara, Mitsuo Kaku, Naoki Aikawa, Kihachiro Shimizu. Pharmacokinetic-pharmacodynamic relationship of arbekacin for treatment of patients infected with methicillin-resistant Staphylococcus aureus. Antimicrobial agents and chemotherapy. 2006 Nov; 50(11):3763-9. doi: 10.1128/aac.00480-05. [PMID: 17065622]
  • Yong Jin, Jin-Wook Jang, Chang-Hoon Han, Mun-Han Lee. Development of immunoassays for the detection of kanamycin in veterinary fields. Journal of veterinary science. 2006 Jun; 7(2):111-7. doi: 10.4142/jvs.2006.7.2.111. [PMID: 16645333]
  • Shigeo Yamamura, Keiko Kawada, Rieko Takehira, Kenji Nishizawa, Shirou Katayama, Masaaki Hirano, Yasunori Momose. Artificial neural network modeling to predict the plasma concentration of aminoglycosides in burn patients. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2004 May; 58(4):239-44. doi: 10.1016/j.biopha.2003.12.012. [PMID: 15183849]
  • Toshimi Kimura, Keisuke Sunakawa, Nobuo Matsuura, Hiroaki Kubo, Shigehiko Shimada, Kazuo Yago. Population pharmacokinetics of arbekacin, vancomycin, and panipenem in neonates. Antimicrobial agents and chemotherapy. 2004 Apr; 48(4):1159-67. doi: 10.1128/aac.48.4.1159-1167.2004. [PMID: 15047516]
  • Tsutomu Yamazaki, Kazuhiro Endo, Kazunori Tominaga, Masataka Fukuda, Shigefumi Maesaki, Giichi Hashikita, Akira Itabashi. [Epidemiological study of Arbekacin-resistant, methicillin resistant Staphylococcus aureus in Saitama Medical School Hospital]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 2004 Apr; 78(4):305-11. doi: 10.11150/kansenshogakuzasshi1970.78.305. [PMID: 15176234]
  • S Yamamura, R Takehira, K Kawada, K Nishizawa, S Katayama, M Hirano, Y Momose. Application of artificial neural network modelling to identify severely ill patients whose aminoglycoside concentrations are likely to fall below therapeutic concentrations. Journal of clinical pharmacy and therapeutics. 2003 Oct; 28(5):425-32. doi: 10.1046/j.0269-4727.2003.00514.x. [PMID: 14632968]
  • Keiji Suzuki. Efficacy and safety of arbekacin for staphylococcal infection in the NICU. Pediatrics international : official journal of the Japan Pediatric Society. 2003 Jun; 45(3):301-6. doi: 10.1046/j.1442-200x.2003.01722.x. [PMID: 12828585]
  • Keiji Suzuki, Kouji Tanikawa, Takashi Matsuzaki. Pharmacokinetics and dosing of arbekacin in preterm and term newborn infants. Pediatrics international : official journal of the Japan Pediatric Society. 2003 Apr; 45(2):175-9. doi: 10.1046/j.1442-200x.2003.01679.x. [PMID: 12709144]
  • Kazuo Kizawa, Miyono Miyazaki, Mineko Nagasawa, Naoko Ogake, Akio Nagai, Takahiro Sanzen, Yasuhito Kawamura. [Attenuation of arbekacin-induced nephrotoxicity in rats by pazufloxacin mesilate]. The Japanese journal of antibiotics. 2003 Feb; 56(1):44-54. doi: NULL. [PMID: 12723398]
  • Toyoji Okubo, Shizuko Iyobe. [Antibacterial activities and PK/PD parameters of aminoglycosides against recent clinical isolates of gram-negative rods]. The Japanese journal of antibiotics. 2002 Oct; 55(5):514-23. doi: NULL. [PMID: 12532635]
  • M Araake, T Hara, A Miyata, M Tani, H Ogawa. [Combination effect of arbekacin and cefepime on mixed culture of MRSA and P. aeruginosa]. The Japanese journal of antibiotics. 2001 Feb; 54(2):69-78. doi: NULL. [PMID: 11338680]
  • T Nakamura, T Kokuryo, M Okuda, Y Hashimoto, K Inui. Effects of arbekacin and vancomycin on release of lactate dehydrogenase and fragmentation of DNA in LLC-PK1 kidney epithelial cells. Pharmaceutical research. 1999 Jul; 16(7):1132-5. doi: 10.1023/a:1011919306412. [PMID: 10450943]
  • S Yamamura, K Nishizawa, M Hirano, Y Momose, A Kimura. Prediction of plasma levels of aminoglycoside antibiotic in patients with severe illness by means of an artificial neural network simulator. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques. 1998 Sep; 1(3):95-101. doi: NULL. [PMID: 10948396]
  • A Arancibia, D Baillarie, M Bravo, J Chávez. Disposition kinetics of dibekacin in patients with renal failure and in patients undergoing hemodialysis. International journal of clinical pharmacology and therapeutics. 1995 Nov; 33(11):623-7. doi: NULL. [PMID: 8688988]
  • K Matsuo, T Uete. [Clinical laboratory approach to evaluate administration dose of arbekacin. Reevaluation of in vitro MIC break points in the disk susceptibility test]. The Japanese journal of antibiotics. 1994 Aug; 47(8):1041-52. doi: NULL. [PMID: 7933533]
  • A Hashimoto, T Ohtsubo, K Tomono, M Kaku, H Koga, S Kohno, K Hara, H Sugiyama, K Taira, Y Inoue. [Clinical effect of the combined therapy of arbekacin and imipenem/cilastatin against methicillin-resistant Staphylococcus aureus]. The Japanese journal of antibiotics. 1994 Jun; 47(6):804-12. doi: . [PMID: 8072190]
  • K Totsuka, K Shimizu, N Mitomi, T Niizato, M Araake. [Evaluation of once-daily administration of arbekacin. Experimental study and determination of pharmacokinetic properties in man]. The Japanese journal of antibiotics. 1994 Jun; 47(6):676-92. doi: NULL. [PMID: 8072176]
  • K Kono, S Takeda, I Tatara, K Arakawa. In vitro activities of arbekacin, alone and in combination, against methicillin-resistant Staphylococcus aureus. The Japanese journal of antibiotics. 1994 Jun; 47(6):710-9. doi: NULL. [PMID: 8072179]
  • T Niizato, M Ohnishi, S Nishiyama, H Asaoka, A Saito. [A study on nephrotoxicity of arbekacin and vancomycin in rats]. The Japanese journal of antibiotics. 1994 Jun; 47(6):664-75. doi: NULL. [PMID: 8072175]
  • M Kuwabara, F Konishi, T Yokoyama, T Kodama, T Santoh, S Nakai, N Miyoshi, T Kurimura, T Miyazawa, K Arita. [Clinical efficacy of arbekacin in deep MRSA infection. Including follow-up study after the termination of chemotherapy]. The Japanese journal of antibiotics. 1994 Jun; 47(6):771-80. doi: NULL. [PMID: 8072186]
  • I Hayashi, M Inoue, H Hashimoto. [Nationwide investigation in Japan of the status of MRSA infections and usefulness of arbekacin]. The Japanese journal of antibiotics. 1994 Jun; 47(6):595-605. doi: NULL. [PMID: 8072167]
  • S Ichiyama, K Shimokata. [Clinical efficacy of arbekacin on MRSA infections]. The Japanese journal of antibiotics. 1994 Jun; 47(6):731-5. doi: NULL. [PMID: 8072181]
  • T Kawashima, T Shishibara, H Nakamura, T Kuriyama, S Kanno, M Watanabe, N Kikuchi, F Kunitomo, F Yamagishi, F Mizutani. [Clinical efficacy of arbekacin on MRSA pneumonia]. The Japanese journal of antibiotics. 1994 Jun; 47(6):741-50. doi: NULL. [PMID: 8072183]
  • S Odagiri, M Sumitomo, K Takahashi, F Matsumoto, I Sakurai, T Imai, K Yoshikawa, A Ito, M Sugiyama, M Suzuki. [An evaluation study on arbekacin for MRSA-infectious diseases including pneumonia, septicemia and others]. The Japanese journal of antibiotics. 1994 Jun; 47(6):751-62. doi: NULL. [PMID: 8072184]
  • H Hamazaki, A Horiuchi, H Hasegawa, T Masaoka, T Kitani, Y Kanayama, H Sugiyama, N Tatsumi, T Kageyama, H Uchino. [Clinical efficacy of arbekacin on MRSA infections with hematopoietic disorders. The Hanshin Study Group of Hematopoietic Disorders and Infections]. The Japanese journal of antibiotics. 1994 Jun; 47(6):763-70. doi: NULL. [PMID: 8072185]
  • I Komiya, N Mitomi, T Kuribayashi, H Takata. Toxicokinetic approach for evaluating respiratory depression effect of aminoglycoside antibiotics: species differences in drug susceptibility. Biopharmaceutics & drug disposition. 1993 Jul; 14(5):443-54. doi: 10.1002/bdd.2510140510. [PMID: 8218962]
  • Y Ito, H Tokuyama, S Yamada, H Komeda, Y Takahashi, M Okano, A Saitoh, T Deguchi, M Kanematsu, Y Kawada. [A study of methicillin-resistant Staphylococcus aureus (MRSA) infection in urological field]. Nihon Hinyokika Gakkai zasshi. The japanese journal of urology. 1993 Mar; 84(3):514-20. doi: 10.5980/jpnjurol1989.84.514. [PMID: 8515639]
  • K Deguchi, N Yokota, M Koguchi, Y Suzuki, K Suzuki, S Fukayama, R Ishihara. [Bacteriological evaluations of combination effects with cefotiam and other antimicrobial agents against methicillin-resistant Staphylococcus aureus. II. Synergistic actions of cefotiam with arbekacin and minocycline]. The Japanese journal of antibiotics. 1993 Feb; 46(2):123-9. doi: NULL. [PMID: 8331772]
  • S Arai, R Kawamura, H Kamiya, T Ishii, M Sakurai. The in vivo and in vitro postantibiotic effect of aminoglycosides using a clinically isolated micro-organism. Acta paediatrica Japonica : Overseas edition. 1993 Feb; 35(1):17-21. doi: 10.1111/j.1442-200x.1993.tb02998.x. [PMID: 8460539]
  • S Arakawa, H Maeda, A Fujii, S Kamidono, K Hamada, S Miyazaki, S Hara. [Clinical study of aminoglycosides on renal dysfunction--pharmacokinetics of arbekacin and its elimination effects by hemodialysis and adsorption with charcoal]. Hinyokika kiyo. Acta urologica Japonica. 1989 Apr; 35(4):697-704. doi: . [PMID: 2735273]
  • H Kumon, A Mizuno, Y Nasu, M Tsugawa, M Kishi, H Ohmori. [Pharmacokinetics of arbekacin in healthy volunteers and patients with renal insufficiency]. The Japanese journal of antibiotics. 1989 Jan; 42(1):200-7. doi: NULL. [PMID: 2709618]
  • I Kitasato, T Niizato, S Inouye. Effect of glucarolactam on low-dose nephrotoxicities of dibekacin and gentamicin in Fischer rats. Drugs under experimental and clinical research. 1989; 15(6-7):249-59. doi: NULL. [PMID: 2591297]
  • J P Mallie, C Billerey. [Experimental study of nephrotoxicity: effects, on the newborn rat kidney, of aminoglycoside administration during gestation]. Nephrologie. 1989; 10(1):27-31. doi: NULL. [PMID: 2716942]
  • I Kitasato, T Niizato, T Watanabe, S Inouye. Reduction of dibekacin-induced nephrotoxicity in the rat by the formation of N-alkylsulfonate derivatives. Drugs under experimental and clinical research. 1989; 15(6-7):239-47. doi: NULL. [PMID: 2591296]
  • M Ollagnier, C Guy. [Aminoglycoside-induced nephrotoxicity. Evaluation of drug surveillance centers]. Therapie. 1988 Aug; 43(5):405-6. doi: NULL. [PMID: 3227501]
  • B Olier, J P Morin, N Thomas, J P Fillastre. [Habekacin: a new aminoglycoside. Study of nephrotoxicity in rats in comparison with gentamicin, netilmicin and amikacin]. Pathologie-biologie. 1988 Jun; 36(6):795-800. doi: NULL. [PMID: 3047639]
  • G A Loeuille, R Cournol, J Delnatte, G Martin. [Plasma level of dibekacin in children with mucoviscidosis. Comparison with a control population]. Annales de pediatrie. 1987 Nov; 34(9):713-7. doi: NULL. [PMID: 3426082]
  • M Takahashi, Y Aramaki, A Inaba, S Tsuchiya. Inhibition of alkaline phosphatase activity and D-glucose uptake in rat renal brush-border membrane vesicles by aminoglycosides. Biochimica et biophysica acta. 1987 Sep; 903(1):31-6. doi: 10.1016/0005-2736(87)90152-0. [PMID: 3651455]
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