ALVERINE (BioDeep_00000600195)
代谢物信息卡片
化学式: C20H27N (281.21433820000004)
中文名称: 阿尔维林
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCN(CCCC1=CC=CC=C1)CCCC2=CC=CC=C2
InChI: InChI=1S/C20H27N/c1-2-21(17-9-15-19-11-5-3-6-12-19)18-10-16-20-13-7-4-8-14-20/h3-8,11-14H,2,9-10,15-18H2,1H3
描述信息
A - Alimentary tract and metabolism > A03 - Drugs for functional gastrointestinal disorders > A03A - Drugs for functional gastrointestinal disorders
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010276 - Parasympatholytics
C78272 - Agent Affecting Nervous System > C66880 - Anticholinergic Agent
同义名列表
1 个代谢物同义名
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:518413
- KEGGdrug: D07440
- PubChem: 3678
- Metlin: METLIN43933
- DrugBank: DB01616
- ChEMBL: CHEMBL253371
- CAS: 150-59-4
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lionel Bueno, Catherine Beaufrand, Vassilia Theodorou, Marie-Christine Andro-Delestrain. Influence of simethicone and alverine on stress-induced alterations of colonic permeability and sensitivity in rats: beneficial effect of their association.
The Journal of pharmacy and pharmacology.
2013 Apr; 65(4):567-73. doi:
10.1111/jphp.12021. [PMID: 23488786] - Gaurang R Shah, Chinmoy Ghosh, Bharat T Thaker. Determination of pregabalin in human plasma by electrospray ionisation tandem mass spectroscopy.
Journal of advanced pharmaceutical technology & research.
2010 Jul; 1(3):354-7. doi:
10.4103/0110-5558.72423. [PMID: 22247871] - Chinmoy Ghosh, Vijay Jha, Ramesh Ahir, Sujal Shah, C P Shinde, Bhaswat S Chakraborty. A rapid and most sensitive liquid chromatography/tandem mass spectrometry method for simultaneous determination of alverine and its major metabolite, para hydroxy alverine, in human plasma: application to a pharmacokinetic and bioequivalence study.
Drug testing and analysis.
2010 Jun; 2(6):284-91. doi:
10.1002/dta.130. [PMID: 20564607] - Samia Ammar, Hayet Edziri, Mohamed Ali Mahjoub, Rym Chatter, Abderrahman Bouraoui, Zine Mighri. Spasmolytic and anti-inflammatory effects of constituents from Hertia cheirifolia.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2009 Dec; 16(12):1156-61. doi:
10.1016/j.phymed.2009.03.012. [PMID: 19403291] - Noel A Gomes, Avdhoot Laud, Ashutosh Pudage, Santosh S Joshi, Vikas V Vaidya, Jayram A Tandel. Validated LC-MS/MS method for determination of Alverine and one of its hydroxy metabolites in human plasma along with its application to a bioequivalence study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2009 Jan; 877(3):197-206. doi:
10.1016/j.jchromb.2008.12.013. [PMID: 19110477] - Alexander C Ford, Nicholas J Talley, Brennan M R Spiegel, Amy E Foxx-Orenstein, Lawrence Schiller, Eamonn M M Quigley, Paul Moayyedi. Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta-analysis.
BMJ (Clinical research ed.).
2008 Nov; 337(?):a2313. doi:
10.1136/bmj.a2313. [PMID: 19008265] - G S Srivastava, A N Smith, N S Painter. Sterculia bulk-forming agent with smooth-muscle relaxant versus bran in diverticular disease.
British medical journal.
1976 Feb; 1(6005):315-8. doi:
10.1136/bmj.1.6005.315. [PMID: 764934]