Prednicarbate (BioDeep_00000599972)

   


代谢物信息卡片


Prednicarbate

化学式: C27H36O8 (488.241)
中文名称: 泼尼甲酸盐-d3, 泼尼卡酯
谱图信息: 最多检出来源 not specific(not specific) 0%

分子结构信息

SMILES: CCC(=O)OCC(=O)C1(CCC2C1(CC(C3C2CCC4=CC(=O)C=CC34C)O)C)OC(=O)OCC
InChI: InChI=1S/C27H36O8/c1-5-22(31)34-15-21(30)27(35-24(32)33-6-2)12-10-19-18-8-7-16-13-17(28)9-11-25(16,3)23(18)20(29)14-26(19,27)4/h9,11,13,18-20,23,29H,5-8,10,12,14-15H2,1-4H3/t18-,19-,20-,23+,25-,26-,27-/m0/s1

描述信息

D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07A - Corticosteroids, plain > D07AC - Corticosteroids, potent (group iii)
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent
D000893 - Anti-Inflammatory Agents

同义名列表

1 个代谢物同义名

Prednicarbate



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • P Schlupp, T Blaschke, K D Kramer, H-D Höltje, W Mehnert, M Schäfer-Korting. Drug release and skin penetration from solid lipid nanoparticles and a base cream: a systematic approach from a comparison of three glucocorticoids. Skin pharmacology and physiology. 2011; 24(4):199-209. doi: 10.1159/000324053. [PMID: 21346400]
  • J Reuter, A Jocher, J Stump, B Grossjohann, G Franke, C M Schempp. Investigation of the anti-inflammatory potential of Aloe vera gel (97.5\%) in the ultraviolet erythema test. Skin pharmacology and physiology. 2008; 21(2):106-10. doi: 10.1159/000114871. [PMID: 18253066]
  • Annekathrin Haberland, Claudia Santos Maia, Katja Jores, Martin Dürrfeld, Wolfgang Mehnert, Ingolf Schimke, Bruno Christ, Monika Schäfer-Korting. Albumin effects on drug absorption and metabolism in reconstructed epidermis and excised pig skin. ALTEX. 2003; 20(1):3-9. doi: NULL. [PMID: 12579349]
  • C Santos Maia, W Mehnert, M Schaller, H C Korting, A Gysler, A Haberland, M Schäfer-Korting. Drug targeting by solid lipid nanoparticles for dermal use. Journal of drug targeting. 2002 Sep; 10(6):489-95. doi: 10.1080/1061186021000038364. [PMID: 12575739]
  • T Moshang. Prednicarbate emollient cream 0.1\% in pediatric patients with atopic dermatitis. Cutis. 2001 Jul; 68(1):63-9. doi: NULL. [PMID: 11480151]
  • C S Maia, W Mehnert, M Schäfer-Korting. Solid lipid nanoparticles as drug carriers for topical glucocorticoids. International journal of pharmaceutics. 2000 Mar; 196(2):165-7. doi: 10.1016/s0378-5173(99)00413-5. [PMID: 10699710]
  • J Barth, G Hochhaus, H Derendorf, K H Lehr, T Höhler, H Moellmann. Prednicarbate after different forms of administration. Plasma levels of drug and metabolites and effects on endogenous cortisol levels in humans. Current problems in dermatology. 1993; 21(?):147-56. doi: NULL. [PMID: 8299368]
  • T M Ernst. [Reaction of autogenous cortisol production in patients with extensive psoriasis vulgaris or atopic dermatitis following external administration of a 0.25\% prednicarbate salve (W/O emulsion)]. Zeitschrift fur Hautkrankheiten. 1986; 61 Suppl 1(?):74-9. doi: NULL. [PMID: 3010589]
  • F Schröpl. [Clinical studies with prednicarbate with special reference to double-blind comparisons with common therapeutic preparations]. Zeitschrift fur Hautkrankheiten. 1986; 61 Suppl 1(?):80-7. doi: NULL. [PMID: 3705676]
  • W Petri, P J Frosch, C Savopoulos, W Rupp, W Sittig. [Galenic and clinico-pharmacologic studies of prednicarbate (Hoe 777)]. Zeitschrift fur Hautkrankheiten. 1986; 61 Suppl 1(?):62-73. doi: ". [PMID: 3705674]