IODIPAMIDE (BioDeep_00000598060)

   


代谢物信息卡片


IODIPAMIDE

化学式: C20H14I6N2O6 (1139.512)
中文名称: 碘帕胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=C(C(=C(C(=C1I)NC(=O)CCCCC(=O)NC2=C(C=C(C(=C2I)C(=O)O)I)I)I)C(=O)O)I
InChI: InChI=1S/C20H14I6N2O6/c21-7-5-9(23)17(15(25)13(7)19(31)32)27-11(29)3-1-2-4-12(30)28-18-10(24)6-8(22)14(16(18)26)20(33)34/h5-6H,1-4H2,(H,27,29)(H,28,30)(H,31,32)(H,33,34)

描述信息

V - Various > V08 - Contrast media > V08A - X-ray contrast media, iodinated > V08AC - Watersoluble, hepatotropic x-ray contrast media
D006133 - Growth Substances > D010937 - Plant Growth Regulators > D014283 - Triiodobenzoic Acids

同义名列表

1 个代谢物同义名

IODIPAMIDE



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Silvia Gazzin, Nathalie Strazielle, Claudio Tiribelli, Jean-François Ghersi-Egea. Transport and metabolism at blood-brain interfaces and in neural cells: relevance to bilirubin-induced encephalopathy. Frontiers in pharmacology. 2012; 3(?):89. doi: 10.3389/fphar.2012.00089. [PMID: 22629246]
  • Ali J Ryan, Jamie Ghuman, Patricia A Zunszain, Chun-wa Chung, Stephen Curry. Structural basis of binding of fluorescent, site-specific dansylated amino acids to human serum albumin. Journal of structural biology. 2011 Apr; 174(1):84-91. doi: 10.1016/j.jsb.2010.10.004. [PMID: 20940056]
  • Francesco Busetti, Kathryn L Linge, Justin W Blythe, Anna Heitz. Rapid analysis of iodinated X-ray contrast media in secondary and tertiary treated wastewater by direct injection liquid chromatography-tandem mass spectrometry. Journal of chromatography. A. 2008 Dec; 1213(2):200-8. doi: 10.1016/j.chroma.2008.10.021. [PMID: 18980771]
  • Qundan Zhang, Yanyan Huang, Rui Zhao, Guoquan Liu, Yi Chen. Determining binding sites of drugs on human serum albumin using FIA-QCM. Biosensors & bioelectronics. 2008 Sep; 24(1):48-54. doi: 10.1016/j.bios.2008.03.009. [PMID: 18436441]
  • Patricia A Zunszain, Jamie Ghuman, Antony F McDonagh, Stephen Curry. Crystallographic analysis of human serum albumin complexed with 4Z,15E-bilirubin-IXalpha. Journal of molecular biology. 2008 Aug; 381(2):394-406. doi: 10.1016/j.jmb.2008.06.016. [PMID: 18602119]
  • E Alibrahim, R N Gibson, J Vincent, T Speer, N Collier, C Jardine. Spiral computed tomography-intravenous cholangiography with three-dimensional reconstructions for imaging the biliary tree. Australasian radiology. 2006 Apr; 50(2):136-42. doi: 10.1111/j.1440-1673.2006.01557.x. [PMID: 16635032]
  • Robert N Gibson, Janette M Vincent, Tony Speer, Neil A Collier, Keith Noack. Accuracy of computed tomographic intravenous cholangiography (CT-IVC) with iotroxate in the detection of choledocholithiasis. European radiology. 2005 Aug; 15(8):1634-42. doi: 10.1007/s00330-004-2606-8. [PMID: 15627178]
  • P Maniatis, C Triantopoulou, E Sofianou, I Siafas, E Psatha, C Dervenis, E Koulentianos. Virtual CT cholangiography in patients with choledocholithiasis. Abdominal imaging. 2003 Jul; 28(4):536-44. doi: 10.1007/s00261-002-0062-y. [PMID: 14580098]
  • H Toyoda, K Hayakawa, M Kikkawa, H Fukushima, M Kataoka, S Mukaihara, K Nishimura, S Kawakami. Usefulness of three-dimensional CT cholangiography for patients prior to laparoscopic cholecystectomy. Radiation medicine. 2000 May; 18(3):161-6. doi: NULL. [PMID: 10972546]
  • Iu K Napolov. [The effect of epsilon-aminocaproic acid and prednisolone on the activation of the complement system due to x-ray contrast agents in rats in vitro]. Eksperimental'naia i klinicheskaia farmakologiia. 1997 Mar; 60(2):62-4. doi: NULL. [PMID: 9206574]
  • K Yamasaki, T Maruyama, U Kragh-Hansen, M Otagiri. Characterization of site I on human serum albumin: concept about the structure of a drug binding site. Biochimica et biophysica acta. 1996 Jul; 1295(2):147-57. doi: 10.1016/0167-4838(96)00013-1. [PMID: 8695640]
  • W Krause, D Niehues. Biochemical characterization of x-ray contrast media. Investigative radiology. 1996 Jan; 31(1):30-42. doi: 10.1097/00004424-199601000-00006. [PMID: 8850363]
  • S M Stockberger, J L Wass, S Sherman, G A Lehman, K K Kopecky. Intravenous cholangiography with helical CT: comparison with endoscopic retrograde cholangiography. Radiology. 1994 Sep; 192(3):675-80. doi: 10.1148/radiology.192.3.8058932. [PMID: 8058932]
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  • Iu K Napolov, N L Shimanovskiĭ, E N Bolotova, N M Borsukova, P V Sergeev. [The effect of x-ray contrast media on the amount of thromboxane and prostacyclin in the blood of man and rats in vivo and in vitro]. Eksperimental'naia i klinicheskaia farmakologiia. 1993 Sep; 56(5):41-3. doi: NULL. [PMID: 8312809]
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  • Iu K Napolov, N M Borsukova, N L Shimanovskiĭ. [Effects of contrast media on interleukin-2 levels in human plasma in vitro]. Biulleten' eksperimental'noi biologii i meditsiny. 1992 Sep; 114(9):288-90. doi: NULL. [PMID: 1477362]
  • R H Elsner, K Ziegler. Radiation inactivation of multispecific transport systems for bile acids and xenobiotics in basolateral rat liver plasma membrane vesicles. The Journal of biological chemistry. 1992 May; 267(14):9788-93. doi: 10.1016/s0021-9258(19)50162-4. [PMID: 1577813]
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  • P V Sergeev, Iu K Napolov, N A Konstantinova, N L Shimanovskiĭ. [The effect of x-ray contrast agents on the concentration and size of immune complexes in the blood]. Farmakologiia i toksikologiia. 1990 Jul; 53(4):54-6. doi: NULL. [PMID: 2226763]
  • E C Lasser, S G Lyon. Inhibition of angiotensin-converting enzyme by contrast media. I. In vitro findings. Investigative radiology. 1990 Jun; 25(6):698-702. doi: 10.1097/00004424-199006000-00014. [PMID: 2354933]
  • P V Sergeev, A Ia Kul'berg, N L Shimanovskiĭ, Iu K Napolov, S V Ukhanov. [Effect of x-ray contrast substances on the complement system of rats]. Biulleten' eksperimental'noi biologii i meditsiny. 1989 Jun; 107(6):716-8. doi: NULL. [PMID: 2790171]
  • L Lauteala, M Kormano, M R Violante. Accumulation and elimination of particulate iodipamide ethyl ester in the lungs and kidneys of the rat. A morphological study. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 1988 Jul; 96(7):660-6. doi: 10.1111/j.1699-0463.1988.tb00926.x. [PMID: 3408591]
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  • M S Sands, M R Violante, G Gadeholt. Computed tomographic enhancement of liver and spleen in the dog with iodipamide ethyl ester particulate suspensions. Investigative radiology. 1987 May; 22(5):408-16. doi: 10.1097/00004424-198705000-00009. [PMID: 3597009]
  • N O Hoem, G Briseid. Acetylcysteine in rats: inhibition of activation of prekallikrein and factor XII--protection against dextran-induced blood pressure fall. Pharmacology & toxicology. 1987 Feb; 60(2):140-4. doi: 10.1111/j.1600-0773.1987.tb01513.x. [PMID: 2437551]
  • N O Hoem, G Briseid, S Ekelund, S Salvesen. Effects of intravenous radiographic contrast media on the blood pressure and on factors of the contact activation system in the rat. Acta pharmacologica et toxicologica. 1986 Sep; 59(3):189-94. doi: 10.1111/j.1600-0773.1986.tb00153.x. [PMID: 2432754]
  • L Lauteala, M Kormano, M R Violante. Response of white blood cells to iodipamide ethyl ester particles. Investigative radiology. 1986 Jul; 21(7):562-5. doi: 10.1097/00004424-198607000-00008. [PMID: 3733383]
  • M Täfler, K Ziegler, M Frimmer. Iodipamide uptake by rat liver plasma membrane vesicles enriched in the sinusoidal fraction: evidence for a carrier-mediated transport dependent on membrane potential. Biochimica et biophysica acta. 1986 Feb; 855(1):157-68. doi: 10.1016/0005-2736(86)90200-2. [PMID: 3942739]
  • S E Seltzer, C Hamilton, D VanDeripe. Experimental evaluation of iosefamate meglumine and its derivatives as hepatobiliary CT contrast agents. AJR. American journal of roentgenology. 1985 Jul; 145(1):67-72. doi: 10.2214/ajr.145.1.67. [PMID: 3873857]
  • H K Beyer, B Schulze. [Immediate effect of x-ray contrast media on thyroid hormone parameters]. Nuklearmedizin. Nuclear medicine. 1985 Jun; 24(3):122-6. doi: NULL. [PMID: 3932974]
  • J Torras, A Martínez Castelao, R Romero, J Alsina. [Acute renal failure caused by iodinated contrast material]. Medicina clinica. 1985 May; 84(19):772-6. doi: NULL. [PMID: 4033249]
  • A Milton, B Odlind. Renal tubular accumulation of organic substances: a new in vivo method which differentiates between luminal and peritubular uptake. Acta physiologica Scandinavica. 1985 Mar; 123(3):237-48. doi: 10.1111/j.1748-1716.1985.tb07584.x. [PMID: 3933280]
  • I Myara, M S Chamaki, C Lagrange, A Lemonnier. [Interference of several radiological contrast media in the determination of proteinuria]. Annales de biologie clinique. 1985; 43(4):347-8. doi: NULL. [PMID: 4091298]
  • S E Seltzer, P M Shulkin, D F Adams, M A Davis, G B Hoey, R M Hopkins, M E Bosworth. Usefulness of liposomes carrying losefamate for CT opacification of liver and spleen. AJR. American journal of roentgenology. 1984 Sep; 143(3):575-9. doi: 10.2214/ajr.143.3.575. [PMID: 6331738]
  • L Lauteala, M Kormano, M R Violante. Effect of intravenously administered iodipamide ethyl ester particles on rat liver morphology. Investigative radiology. 1984 Mar; 19(2):133-41. doi: 10.1097/00004424-198403000-00011. [PMID: 6533104]
  • I von Zabern, H Przyklenk, R Nolte, W Vogt. Effect of metrizamide, a nonionic radiographic contrast agent, on human serum complement. Comparison with ionic contrast media. International archives of allergy and applied immunology. 1984; 73(4):321-9. doi: 10.1159/000233492. [PMID: 6421748]
  • G Limido. [Problems related to the radiographic study of the biliary tract using oral or intravenous contrast media. Main side effects and biochemical changes induced by the administration of contrast media]. Minerva dietologica e gastroenterologica. 1984 Jan; 30(1):9-15. doi: NULL. [PMID: 6374500]
  • T Sherwood. Nephrotoxicity of radiocontrast media in ischemic renal failure in rabbits. Nephron. 1983; 34(3):205. doi: 10.1159/000183013. [PMID: 6877454]
  • P J Durda, R J Pagano, N Bauman, J A Brockman. Effects of iodipamide on human C3 and factor B in vitro. The Journal of allergy and clinical immunology. 1982 Nov; 70(5):353-60. doi: 10.1016/0091-6749(82)90024-0. [PMID: 6922882]
  • M D Apstein, S J Robins. Effect of organic anions on biliary lipids in the rat. Gastroenterology. 1982 Nov; 83(5):1120-6. doi: 10.1016/s0016-5085(82)80082-6. [PMID: 7117794]
  • L C Hutton, J F Tuckerman, A R Henderson. Elevation of serum lactate dehydrogenase-5 following methylglucamine iodipamide (Cholografin/Biligrafin) infusion for intravenous cholangiography. Clinica chimica acta; international journal of clinical chemistry. 1982 Jul; 122(2):279-82. doi: 10.1016/0009-8981(82)90287-x. [PMID: 7105412]
  • S G Schultz, K J Lavelle, R Swain. Nephrotoxicity of radiocontrast media in ischemic renal failure in rabbits. Nephron. 1982; 32(2):113-7. doi: 10.1159/000182829. [PMID: 6129580]
  • A A Moss, A C Brito. Computed tomography of the liver in rhesus monkeys following losefamate meglumine administration. Radiology. 1981 Oct; 141(1):123-7. doi: 10.1148/radiology.141.1.7291516. [PMID: 7291516]
  • A G Belykh. [Effect of contrast media on the structure and function of hepatocyte plasma membranes]. Farmakologiia i toksikologiia. 1981 May; 44(3):322-6. doi: NULL. [PMID: 6456930]
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  • P V Sergeev, A G Belykh. [Reaction between x-ray contrast media and dyes and hepatocyte plasma membranes]. Farmakologiia i toksikologiia. 1981 Mar; 44(2):195-200. doi: NULL. [PMID: 7274428]
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  • S K Lin, A A Moss, S Riegelman. Saturation kinetics of iodipamide. Investigative radiology. 1977 Mar; 12(2):175-9. doi: 10.1097/00004424-197703000-00013. [PMID: 856758]
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