Dexamethasone Phosphate (BioDeep_00000597210)

   


代谢物信息卡片


Dexamethasone Phosphate

化学式: C22H30FO8P (472.1662242)
中文名称: 地塞米松磷酸酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)(O)O)O)C)O)F)C
InChI: InChI=1S/C22H30FO8P/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30)/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

描述信息

D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
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SARS

同义名列表

1 个代谢物同义名

Dexamethasone Phosphate



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Dayle McClintock, Michaela Austel, Robert M Gogal, Frane Banovic. Oral dexamethasone sodium phosphate solution significantly reduces pruritus and clinical lesions in feline hypersensitivity dermatitis: an open-label study. Veterinary dermatology. 2021 Oct; 32(5):497-e137. doi: 10.1111/vde.13006. [PMID: 34351657]
  • Selena de Wasseige, Khristine Picotte, Jean-Pierre Lavoie. Nebulized dexamethasone sodium phosphate in the treatment of horses with severe asthma. Journal of veterinary internal medicine. 2021 May; 35(3):1604-1611. doi: 10.1111/jvim.16113. [PMID: 33817859]
  • Li-Juan Zhao, Ben-Sheng Dong, Hui Zhang, Dao-Fang Ding, Hua-Zong Guan, Ya-Fang Li, Guo-Hui Zhang, Shu-Yu Zhang, Kun Niu, Hong Zhang. Intermittent pressure imitating rolling manipulation ameliorates injury in skeletal muscle cells through oxidative stress and lipid metabolism signalling pathways. Gene. 2021 Apr; 778(?):145460. doi: 10.1016/j.gene.2021.145460. [PMID: 33515727]
  • Sanjukta Duarah, Manisha Sharma, Jingyuan Wen. Rapid and simultaneous determination of dexamethasone and dexamethasone sodium phosphate using HPLC-UV: Application in microneedle-assisted skin permeation and deposition studies. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2021 Apr; 1170(?):122609. doi: 10.1016/j.jchromb.2021.122609. [PMID: 33713946]
  • Dhananjay Jadhav, Pradeep Vavia. Dexamethasone Sodium Phosphate Loaded Modified Cyclodextrin Based Nanoparticles: An Efficient Treatment for Rheumatoid Arthritis. Journal of pharmaceutical sciences. 2021 03; 110(3):1206-1218. doi: 10.1016/j.xphs.2020.10.023. [PMID: 33075379]
  • Heather K Knych, Daniel Weiner, Rick M Arthur, Russell Baden, Daniel S McKemie, Philip H Kass. Serum concentrations, pharmacokinetic/pharmacodynamic modeling, and effects of dexamethasone on inflammatory mediators following intravenous and oral administration to exercised horses. Drug testing and analysis. 2020 Aug; 12(8):1087-1101. doi: 10.1002/dta.2862. [PMID: 32436346]
  • S Mainguy-Seers, A Bessonnat, K Picotte, J-P Lavoie. Nebulisation of dexamethasone sodium phosphate for the treatment of severe asthmatic horses. Equine veterinary journal. 2019 Sep; 51(5):641-645. doi: 10.1111/evj.13091. [PMID: 30849189]
  • Augusto F Schmidt, Matthew W Kemp, Mark Milad, Lisa A Miller, James P Bridges, Michael W Clarke, Paranthaman S Kannan, Alan H Jobe. Oral dosing for antenatal corticosteroids in the Rhesus macaque. PloS one. 2019; 14(9):e0222817. doi: 10.1371/journal.pone.0222817. [PMID: 31536601]
  • Jessica K Hartman, Tyler Beames, Bethany Parks, Daniel Doheny, Gina Song, Alina Efremenko, Miyoung Yoon, Briana Foley, Chad Deisenroth, Patrick D McMullen, Rebecca A Clewell. An in vitro approach for prioritization and evaluation of chemical effects on glucocorticoid receptor mediated adipogenesis. Toxicology and applied pharmacology. 2018 09; 355(?):112-126. doi: 10.1016/j.taap.2018.05.016. [PMID: 29782964]
  • Harris Sultan, Clint Kellogg, Jaafar El-Annan. Retinal Pigment Epithelium Tears in a 67-Year-Old Man. JAMA ophthalmology. 2018 05; 136(5):583-584. doi: 10.1001/jamaophthalmol.2017.4445. [PMID: 29423507]
  • Kongnara Papangkorn, John W Higuchi, Balbir Brar, William I Higuchi. Ocular Drug Distribution and Safety of a Noninvasive Ocular Drug Delivery System of Dexamethasone Sodium Phosphate in Rabbit. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 2018 05; 34(4):325-334. doi: 10.1089/jop.2017.0093. [PMID: 29432054]
  • A D Haspel, S Giguère, K A Hart, L J Berghaus, J L Davis. Bioavailability and tolerability of nebulised dexamethasone sodium phosphate in adult horses. Equine veterinary journal. 2018 Jan; 50(1):85-90. doi: 10.1111/evj.12724. [PMID: 28719014]
  • Alec N Salt, Jared J Hartsock, Fabrice Piu, Jennifer Hou. Dexamethasone and Dexamethasone Phosphate Entry into Perilymph Compared for Middle Ear Applications in Guinea Pigs. Audiology & neuro-otology. 2018; 23(4):245-257. doi: 10.1159/000493846. [PMID: 30497073]
  • Tao Wu, Jianguo Jiang, Luna Yang, Haifeng Li, Wanjing Zhang, Yangyang Chen, Binggong Zhao, Boda Kong, Ping Lu, Zhenzhen Zhao, Jiawei Zhu, Zhengwei Fu. Timing of glucocorticoid administration determines severity of lipid metabolism and behavioral effects in rats. Chronobiology international. 2017; 34(1):78-92. doi: 10.1080/07420528.2016.1238831. [PMID: 27791398]
  • Jennyfer Cázares-Delgadillo, Adriana Ganem-Rondero, Virginia Merino, Yogeshvar N Kalia. Controlled transdermal iontophoresis for poly-pharmacotherapy: Simultaneous delivery of granisetron, metoclopramide and dexamethasone sodium phosphate in vitro and in vivo. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2016 Mar; 85(?):31-8. doi: 10.1016/j.ejps.2016.01.027. [PMID: 26826281]
  • A M El-Kosasy, Omar Abdel-Aziz, N Magdy, N M El Zahar. Spectrophotometric and chemometric methods for determination of imipenem, ciprofloxacin hydrochloride, dexamethasone sodium phosphate, paracetamol and cilastatin sodium in human urine. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2016 Mar; 157(?):26-33. doi: 10.1016/j.saa.2015.12.011. [PMID: 26709018]
  • Zhen Huang, Wei Yang, Yao Zong, Suo Qiu, Xiaoqing Chen, Xuyuan Sun, Yuting Zhou, Zhiyong Xie, Qianying Gao. A study of the dexamethasone sodium phosphate release properties from a periocular capsular drug delivery system. Drug delivery. 2016; 23(3):849-57. doi: 10.3109/10717544.2014.919543. [PMID: 24865291]
  • Ruth A Kinkead, Christopher T Elliott, Francesca T Cannizzo, Bartolomeo Biolatti, Mark H Mooney. Proteomic identification of plasma proteins as markers of growth promoter abuse in cattle. Analytical and bioanalytical chemistry. 2015 Jun; 407(15):4495-507. doi: 10.1007/s00216-015-8651-0. [PMID: 25912459]
  • Saleh Sulaimana, Mustafa Khamis, Shlomo Nir, Filomena Lelario, Laura Scrano, Sabino Aurelio Bufo, Rafik Karaman. Stability and removal of dexamethasone sodium phosphate from wastewater using modified clays. Environmental technology. 2014 Aug; 35(13-16):1945-55. doi: 10.1080/09593330.2014.888097. [PMID: 24956788]
  • C Guglielmetti, M Mazza, M Pagano, S Carrella, S Sciuto, S Nodari, M Pezzolato, G B Richelmi, E Baioni, M Caramelli, P L Acutis, E Bozzetta. Identification by a proteomic approach of a plasma protein as a possible biomarker of illicit dexamethasone treatment in veal calves. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2014; 31(5):833-8. doi: 10.1080/19440049.2014.900191. [PMID: 24588558]
  • Ghulam Jalani, Chan Woo Jung, Jae Sang Lee, Dong Woo Lim. Fabrication and characterization of anisotropic nanofiber scaffolds for advanced drug delivery systems. International journal of nanomedicine. 2014; 9 Suppl 1(?):33-49. doi: 10.2147/ijn.s51842. [PMID: 24872702]
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  • Michael A Patane, William Schubert, Thomas Sanford, Raymond Gee, Melissa Burgos, William P Isom, Begona Ruiz-Perez. Evaluation of ocular and general safety following repeated dosing of dexamethasone phosphate delivered by transscleral iontophoresis in rabbits. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 2013 Oct; 29(8):760-9. doi: 10.1089/jop.2012.0175. [PMID: 23844757]
  • Carolina Ferranti, Marco Famele, Luca Palleschi, Elena Bozzetta, Marzia Pezzolato, Rosa Draisci. Excretion profile of corticosteroids in bovine urine compared with tissue residues after therapeutic and growth-promoting administration of dexamethasone. Steroids. 2013 Sep; 78(9):803-12. doi: 10.1016/j.steroids.2013.05.002. [PMID: 23684526]
  • Fabrizio Bossa, Vito Annese, Maria Rosa Valvano, Anna Latiano, Giuseppina Martino, Luigia Rossi, Mauro Magnani, Orazio Palmieri, Sonja Serafini, Gianluca Damonte, Ermelinda De Santo, Angelo Andriulli. Erythrocytes-mediated delivery of dexamethasone 21-phosphate in steroid-dependent ulcerative colitis: a randomized, double-blind Sham-controlled study. Inflammatory bowel diseases. 2013 Aug; 19(9):1872-9. doi: 10.1097/mib.0b013e3182874065. [PMID: 23714676]
  • Katayoun Mahdavi Ara, Zahra Akhoondpouramiri, Farhad Raofie. Carrier mediated transport solvent bar microextraction for preconcentration and determination of dexamethasone sodium phosphate in biological fluids and bovine milk samples using response surface methodology. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2013 Jul; 931(?):148-56. doi: 10.1016/j.jchromb.2013.05.022. [PMID: 23792367]
  • Peter N Laver, André Ganswindt, Stefanie B Ganswindt, Kathleen A Alexander. Non-invasive monitoring of glucocorticoid metabolites in banded mongooses (Mungos mungo) in response to physiological and biological challenges. General and comparative endocrinology. 2012 Nov; 179(2):178-83. doi: 10.1016/j.ygcen.2012.08.011. [PMID: 22926328]
  • Anna Gonciarz, Kamil Kus, Małgorzata Szafarz, Maria Walczak, Agnieszka Zakrzewska, Joanna Szymura-Oleksiak. Capillary electrophoresis/frontal analysis versus equilibrium dialysis in dexamethasone sodium phosphate-serum albumin binding studies. Electrophoresis. 2012 Nov; 33(22):3323-30. doi: 10.1002/elps.201200166. [PMID: 23097126]
  • Weina Liu, Yongjun Xu, Jianqiang Lu, Yanmin Zhang, Hui Sheng, Xin Ni. Swimming exercise ameliorates depression-like behaviors induced by prenatal exposure to glucocorticoids in rats. Neuroscience letters. 2012 Aug; 524(2):119-23. doi: 10.1016/j.neulet.2012.07.011. [PMID: 22813978]
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  • Philip A Bird, Daran P Murray, Mei Zhang, Evan J Begg. Intratympanic versus intravenous delivery of dexamethasone and dexamethasone sodium phosphate to cochlear perilymph. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 2011 Aug; 32(6):933-6. doi: 10.1097/mao.0b013e3182255933. [PMID: 21725263]
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  • Mei Zhang, Grant A Moore, Berit P Jensen, Evan J Begg, Philip A Bird. Determination of dexamethasone and dexamethasone sodium phosphate in human plasma and cochlear perilymph by liquid chromatography/tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2011 Jan; 879(1):17-24. doi: 10.1016/j.jchromb.2010.11.003. [PMID: 21112257]
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