16,16-dimethyl-PGE1 (BioDeep_00000594210)

   


代谢物信息卡片


9-oxo-11R,15S-dihydroxy-16,16-dimethyl-13E-prostaenoic acid

化学式: C22H38O5 (382.2719098)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCC(C)(C)C(C=CC1C(CC(=O)C1CCCCCCC(=O)O)O)O
InChI: InChI=1S/C22H38O5/c1-4-5-14-22(2,3)20(25)13-12-17-16(18(23)15-19(17)24)10-8-6-7-9-11-21(26)27/h12-13,16-17,19-20,24-25H,4-11,14-15H2,1-3H3,(H,26,27)/b13-12+/t16-,17-,19-,20-/m1/s1



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • L M Lichtenberger, T N Ahmed, J C Barreto, Y C Kao, E J Dial. Use of fluorescent hydrophobic dyes in establishing the presence of lipids in the gastric mucus gel layer. Journal of clinical gastroenterology. 1992; 14 Suppl 1(?):S82-7. doi: 10.1097/00004836-199206001-00014. [PMID: 1378468]
  • Y Kurebayashi, Y Honda. Protection by 16,16-dimethyl prostaglandin E2 and dibutyryl cyclic AMP against complement-mediated hepatic necrosis in rats. Hepatology (Baltimore, Md.). 1991 Sep; 14(3):545-50. doi: 10.1002/hep.1840140323. [PMID: 1651899]
  • J P Waymack, L L Moldawer, S F Lowry, R F Guzman, C V Okerberg, A D Mason, B A Pruitt. Effect of prostaglandin E in multiple experimental models. IV. Effect on resistance to endotoxin and tumor necrosis factor shock. The Journal of surgical research. 1990 Oct; 49(4):328-32. doi: 10.1016/0022-4804(90)90031-v. [PMID: 2214741]
  • J P Waymack, W T Chance. Effect of prostaglandin E in multiple experimental models: V. Effect on tumor/host interaction. Journal of surgical oncology. 1990 Oct; 45(2):110-6. doi: 10.1002/jso.2930450210. [PMID: 1976854]
  • J P Waymack, W T Chance, J L Nelson, A D Mason. The effect of PGE in multiple experimental models. II. Effect on steady-state levels of plasma and brain amino acids and transmitters. Physiology & behavior. 1989 Jun; 45(6):1201-5. doi: 10.1016/0031-9384(89)90110-8. [PMID: 2573094]
  • C Limas, C J Limas. Homologous regulation of prostaglandin E2 receptors in rat renal medulla. Archives of biochemistry and biophysics. 1987 Nov; 259(1):89-97. doi: 10.1016/0003-9861(87)90473-5. [PMID: 3479947]
  • T L Walden, M Patchen, S L Snyder. 16,16-Dimethyl prostaglandin E2 increases survival in mice following irradiation. Radiation research. 1987 Mar; 109(3):440-8. doi: 10.2307/3577044. [PMID: 3562785]
  • L Makowka, W Lopatin, T Gilas, J Falk, M J Phillips, R Falk. Prevention of cyclosporine (CyA) nephrotoxicity by synthetic prostaglandins. Clinical nephrology. 1986; 25 Suppl 1(?):S89-94. doi: NULL. [PMID: 3708941]
  • K L Raheja, W G Linscheer, C Cho, R Coulson. Failure of exogenous prostaglandin to afford complete protection against acetaminophen-induced hepatotoxicity in the rat. Journal of toxicology and environmental health. 1985; 15(3-4):477-84. doi: 10.1080/15287398509530674. [PMID: 4032494]
  • B I Hirschowitz, E Molina. Analysis of food stimulation of gastrin release in dogs by a panel of inhibitors. Peptides. 1984 Jan; 5(1):35-40. doi: 10.1016/0196-9781(84)90047-0. [PMID: 6143304]
  • L Axelrod, P Lloyd-Jones, A M Ferris, D B Martin. Enhancement of ketosis by 16,16 dimethylprostaglandin E2 during the genesis of diabetic ketoacidosis in rats. Prostaglandins and medicine. 1981 Feb; 6(2):147-52. doi: 10.1016/0161-4630(81)90085-9. [PMID: 6787629]
  • M J Ruwart, B D Rush, N M Friedle, R C Piper, G J Kolaja. Protective effects of 16,16-dimethyl PGE2 on the liver and kidney. Prostaglandins. 1981; 21 Suppl(?):97-102. doi: 10.1016/0090-6980(81)90124-6. [PMID: 7302263]