gemeprost (BioDeep_00000593209)

   


代谢物信息卡片


gemeprost

化学式: C23H38O5 (394.2719098)
中文名称: 吉美前列素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCC(C)(C)C(C=CC1C(CC(=O)C1CCCCC=CC(=O)OC)O)O
InChI: InChI=1S/C23H38O5/c1-5-6-15-23(2,3)21(26)14-13-18-17(19(24)16-20(18)25)11-9-7-8-10-12-22(27)28-4/h10,12-14,17-18,20-21,25-26H,5-9,11,15-16H2,1-4H3/b12-10+,14-13+/t17-,18-,20-,21-/m1/s1

描述信息

G - Genito urinary system and sex hormones > G02 - Other gynecologicals > G02A - Uterotonics > G02AD - Prostaglandins
D012102 - Reproductive Control Agents > D000019 - Abortifacient Agents
C78568 - Prostaglandin Analogue

同义名列表

1 个代谢物同义名

gemeprost



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Marc Bygdeman. Pharmacokinetics of prostaglandins. Best practice & research. Clinical obstetrics & gynaecology. 2003 Oct; 17(5):707-16. doi: 10.1016/s1521-6934(03)00043-9. [PMID: 12972009]
  • A M Henry, M Haukkamaa. Comparison of vaginal misoprostol and gemeprost as pre-treatment in first trimester pregnancy interruption. British journal of obstetrics and gynaecology. 1999 Jun; 106(6):540-3. doi: 10.1111/j.1471-0528.1999.tb08321.x. [PMID: 10426610]
  • P Gavriil, E Jauniaux, B Gulbis, D Jurkovic, S Meuris. Changes in the coelomic fluid composition following two different methods of cervical ripening. Human reproduction (Oxford, England). 1995 Sep; 10(9):2453-5. doi: 10.1093/oxfordjournals.humrep.a136318. [PMID: 8530685]
  • E J Lazda, V R Sams. The effects of gemeprost on the second trimester fetus. British journal of obstetrics and gynaecology. 1995 Sep; 102(9):731-4. doi: 10.1111/j.1471-0528.1995.tb11432.x. [PMID: 7547765]
  • K J Thong, J E Norman, D T Baird. Changes in the concentration of alpha-fetoprotein and placental hormones following two methods of medical abortion in early pregnancy. British journal of obstetrics and gynaecology. 1993 Dec; 100(12):1111-4. doi: 10.1111/j.1471-0528.1993.tb15175.x. [PMID: 7507707]
  • J E Norman, K J Thong, M W Rodger, D T Baird. Medical abortion in women of less than or equal to 56 days amenorrhoea: a comparison between gemeprost (a PGE1 analogue) alone and mifepristone and gemeprost. British journal of obstetrics and gynaecology. 1992 Jul; 99(7):601-6. doi: 10.1111/j.1471-0528.1992.tb13830.x. [PMID: 1525104]
  • K R Petersen, G K Larsen, K Nørring, F R Jensen. Misdiagnosis of interstitial pregnancy followed by uterine cornual rupture during induced midtrimester abortion. Acta obstetricia et gynecologica Scandinavica. 1992 May; 71(4):316-8. doi: 10.3109/00016349209021061. [PMID: 1322630]
  • T Chard, F Olajide, M Kitau. Changes in circulating alphafetoprotein following administration of mifepristone in first trimester pregnancy. British journal of obstetrics and gynaecology. 1990 Nov; 97(11):1030-2. doi: 10.1111/j.1471-0528.1990.tb02477.x. [PMID: 1701323]
  • I T Cameron, D T Baird. The return to ovulation following early abortion: a comparison between vacuum aspiration and prostaglandin. Acta endocrinologica. 1988 Jun; 118(2):161-7. doi: 10.1530/acta.0.1180161. [PMID: 3291533]
  • M W Rodger, D T Baird. Induction of therapeutic abortion in early pregnancy with mifepristone in combination with prostaglandin pessary. Lancet (London, England). 1987 Dec; 2(8573):1415-8. doi: 10.1016/s0140-6736(87)91126-3. [PMID: 2891991]
  • V Dimov, K Gréen, M Bygdeman, N J Christensen. Metabolism of 16, 16-dimethyl-trans-delta 2-prostaglandin E1 methyl ester (ONO-802) following intravenous and vaginal administration to pregnant women. Drug metabolism and disposition: the biological fate of chemicals. 1986 Jul; 14(4):494-502. doi: NULL. [PMID: 2873999]
  • A Kondo, M Kobayashi, T Takita, H Narita. Effect of prostaglandin on urethral resistance and micturition. Urological research. 1983; 11(1):19-22. doi: 10.1007/bf00272704. [PMID: 6574652]
  • K Bremme, P Eneroth, M Bygdeman. Maternal serum hormone changes during abortion induced with 16,16-dimethyl-trans-delta 2-PGE1 methyl ester. Prostaglandins, leukotrienes, and medicine. 1982 Jun; 8(6):647-51. doi: NULL. [PMID: 6955815]
  • K Matsumoto, A Akimoto, K Shibata, S Matsuo, T Muryobayashi, T Sakai, T Tsuda, M Tsuboshima. [Effects of 16,16-Dimethyl-trans-delta 2-PGE1 methyl ester (ONO-802) on uterine, placental and ovarian circulation (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 1981 Oct; 78(4):239-48. doi: 10.1254/fpj.78.239. [PMID: 7327453]