Thiamin diphosphate (BioDeep_00000593099)
代谢物信息卡片
2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethyl phosphono hydrogen phosphate
化学式: C12H18N4O7P2S (424.03714180000003)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCOP(=O)(O)OP(=O)(O)[O-]
InChI: InChI=1S/C12H18N4O7P2S/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21)
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:45931
- PubChem: 644169
- PubChem: 5431
- Metlin: METLIN2832
- DrugBank: DB01987
- ChEMBL: CHEMBL1236235
- MeSH: Thiamine Pyrophosphate
- CAS: 136-09-4
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yehong Li, Mengze Zhou, Huanqiu Li, Chen Dai, Li Yin, Chunxiao Liu, Yuxin Li, Enming Zhang, Xinli Dong, Hui Ji, Qinghua Hu. Macrophage P2Y6 receptor deletion attenuates atherosclerosis by limiting foam cell formation through phospholipase Cβ/store-operated calcium entry/calreticulin/scavenger receptor A pathways.
European heart journal.
2024 Jan; 45(4):268-283. doi:
10.1093/eurheartj/ehad796. [PMID: 38036416] - Yi-Hsin Chung, Ting-Chieh Chen, Wen-Ju Yang, Soon-Ziet Chen, Jia-Ming Chang, Wei-Yu Hsieh, Ming-Hsiun Hsieh. Ectopic expression of a bacterial thiamin monophosphate kinase enhances vitamin B1 biosynthesis in plants.
The Plant journal : for cell and molecular biology.
2023 Nov; ?(?):. doi:
10.1111/tpj.16563. [PMID: 37996996] - Wei-Yu Hsieh, Hsin-Mei Wang, Yi-Hsin Chung, Kim-Teng Lee, Hong-Sheng Liao, Ming-Hsiun Hsieh. THIAMIN REQUIRING2 is involved in thiamin diphosphate biosynthesis and homeostasis.
The Plant journal : for cell and molecular biology.
2022 09; 111(5):1383-1396. doi:
10.1111/tpj.15895. [PMID: 35791282] - Marcel Llavero-Pasquina, Katrin Geisler, Andre Holzer, Payam Mehrshahi, Gonzalo I Mendoza-Ochoa, Shelby A Newsad, Matthew P Davey, Alison G Smith. Thiamine metabolism genes in diatoms are not regulated by thiamine despite the presence of predicted riboswitches.
The New phytologist.
2022 09; 235(5):1853-1867. doi:
10.1111/nph.18296. [PMID: 35653609] - Donogh Maguire, Alana Burns, Dinesh Talwar, Anthony Catchpole, Fiona Stefanowicz, David P Ross, Peter Galloway, Alastair Ireland, Gordon Robson, Michael Adamson, Lesley Orr, Joanna-Lee Kerr, Xenofon Roussis, Eoghan Colgan, Ewan Forrest, David Young, Donald C McMillan. Randomised trial of intravenous thiamine and/or magnesium sulphate administration on erythrocyte transketolase activity, lactate concentrations and alcohol withdrawal scores.
Scientific reports.
2022 04; 12(1):6941. doi:
10.1038/s41598-022-10970-x. [PMID: 35484175] - Donogh Maguire, Anthony Catchpole, Owen Sheerins, Dinesh Talwar, Alana Burns, Mark Blyth, Andrew Shaw, Bryn Jones, Colin Drury, Johann Harten, Innes Smith, Donald C McMillan. The relation between acute changes in the systemic inflammatory response and circulating thiamine and magnesium concentrations after elective knee arthroplasty.
Scientific reports.
2021 05; 11(1):11271. doi:
10.1038/s41598-021-90591-y. [PMID: 34050237] - Mugagga Kalyesubula, Ramgopal Mopuri, Jimmy Asiku, Alexander Rosov, Sara Yosefi, Nir Edery, Samuel Bocobza, Uzi Moallem, Hay Dvir. High-dose vitamin B1 therapy prevents the development of experimental fatty liver driven by overnutrition.
Disease models & mechanisms.
2021 03; 14(3):. doi:
10.1242/dmm.048355. [PMID: 33608323] - Osatohanmwen J Enogieru, Megan L Koleske, Bianca Vora, Huy Ngo, Sook Wah Yee, Derrick Chatad, Marina Sirota, Kathleen M Giacomini. The Effects of Genetic Mutations and Drugs on the Activity of the Thiamine Transporter, SLC19A2.
The AAPS journal.
2021 03; 23(2):35. doi:
10.1208/s12248-021-00562-4. [PMID: 33649974] - Payam Mehrshahi, Ginnie Trinh D T Nguyen, Aleix Gorchs Rovira, Andrew Sayer, Marcel Llavero-Pasquina, Michelle Lim Huei Sin, Elliot J Medcalf, Gonzalo I Mendoza-Ochoa, Mark A Scaife, Alison G Smith. Development of Novel Riboswitches for Synthetic Biology in the Green Alga Chlamydomonas.
ACS synthetic biology.
2020 06; 9(6):1406-1417. doi:
10.1021/acssynbio.0c00082. [PMID: 32496044] - Zeenat B Noordally, Celso Trichtinger, Ivan Dalvit, Manuel Hofmann, Céline Roux, Nicola Zamboni, Lucille Pourcel, Elisabet Gas-Pascual, Alexandra Gisler, Teresa B Fitzpatrick. The coenzyme thiamine diphosphate displays a daily rhythm in the Arabidopsis nucleus.
Communications biology.
2020 05; 3(1):209. doi:
10.1038/s42003-020-0927-z. [PMID: 32372067] - Heidi M Blank, Ophelia Papoulas, Nairita Maitra, Riddhiman Garge, Brian K Kennedy, Birgit Schilling, Edward M Marcotte, Michael Polymenis. Abundances of transcripts, proteins, and metabolites in the cell cycle of budding yeast reveal coordinate control of lipid metabolism.
Molecular biology of the cell.
2020 05; 31(10):1069-1084. doi:
10.1091/mbc.e19-12-0708. [PMID: 32129706] - Jaya Joshi, Jacob S Folz, Jesse F Gregory, Donald R McCarty, Oliver Fiehn, Andrew D Hanson. Rethinking the PDH Bypass and GABA Shunt as Thiamin-Deficiency Workarounds.
Plant physiology.
2019 10; 181(2):389-393. doi:
10.1104/pp.19.00857. [PMID: 31409697] - Kyly C Whitfield, Hou Kroeun, Tim Green, Frank T Wieringa, Mam Borath, Prak Sophonneary, Jeffrey R Measelle, Dare Baldwin, Lisa N Yelland, Shalem Leemaqz, Kathleen Chan, Jelisa Gallant. Thiamine dose response in human milk with supplementation among lactating women in Cambodia: study protocol for a double-blind, four-parallel arm randomised controlled trial.
BMJ open.
2019 07; 9(7):e029255. doi:
10.1136/bmjopen-2019-029255. [PMID: 31292183] - Turgay Ucak, Yucel Karakurt, Gamze Tasli, Ferda Keskin Cimen, Erel Icel, Nezahat Kurt, Ibrahim Ahiskali, Halis Süleyman. The effects of thiamine pyrophosphate on ethanol induced optic nerve damage.
BMC pharmacology & toxicology.
2019 07; 20(1):40. doi:
10.1186/s40360-019-0319-5. [PMID: 31277705] - Laise Rosado-Souza, Sebastian Proost, Michael Moulin, Susan Bergmann, Samuel E Bocobza, Asaph Aharoni, Teresa B Fitzpatrick, Marek Mutwil, Alisdair R Fernie, Toshihiro Obata. Appropriate Thiamin Pyrophosphate Levels Are Required for Acclimation to Changes in Photoperiod.
Plant physiology.
2019 05; 180(1):185-197. doi:
10.1104/pp.18.01346. [PMID: 30837347] - Magdalena Jankowska, Monika Lichodziejewska-Niemierko, Sylwia Małgorzewicz, Bolesław Rutkowski. Biologically active form of vitamin B1 in human peritoneal effluent.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University.
2017 Dec; 26(9):1405-1410. doi:
10.17219/acem/68722. [PMID: 29442462] - Wei-Yu Hsieh, Jo-Chien Liao, Hsin-Tzu Wang, Tzu-Huan Hung, Ching-Chih Tseng, Tsui-Yun Chung, Ming-Hsiun Hsieh. The Arabidopsis thiamin-deficient mutant pale green1 lacks thiamin monophosphate phosphatase of the vitamin B1 biosynthesis pathway.
The Plant journal : for cell and molecular biology.
2017 Jul; 91(1):145-157. doi:
10.1111/tpj.13552. [PMID: 28346710] - Adrian McCann, Øivind Midttun, Kyly C Whitfield, Hou Kroeun, Mam Borath, Prak Sophonneary, Per Magne Ueland, Timothy J Green. Comparable Performance Characteristics of Plasma Thiamine and Erythrocyte Thiamine Diphosphate in Response to Thiamine Fortification in Rural Cambodian Women.
Nutrients.
2017 Jun; 9(7):. doi:
10.3390/nu9070676. [PMID: 28661435] - Mirko Paulikat, Cindy Wechsler, Kai Tittmann, Ricardo A Mata. Theoretical Studies of the Electronic Absorption Spectra of Thiamin Diphosphate in Pyruvate Decarboxylase.
Biochemistry.
2017 04; 56(13):1854-1864. doi:
10.1021/acs.biochem.6b00984. [PMID: 28296385] - Magdalena Jankowska, Paweł Rudnicki-Velasquez, Hanna Storoniak, Przemysław Rutkowski, Bolesław Rutkowski, Karol Krzymiński, Alicja Dębska-Ślizień. Thiamine Diphosphate Status and Dialysis-Related Losses in End-Stage Kidney Disease Patients Treated with Hemodialysis.
Blood purification.
2017; 44(4):294-300. doi:
10.1159/000480651. [PMID: 29080898] - Manaki Mimura, Rémi Zallot, Thomas D Niehaus, Ghulam Hasnain, Satinder K Gidda, Thuy N D Nguyen, Erin M Anderson, Robert T Mullen, Greg Brown, Alexander F Yakunin, Valérie de Crécy-Lagard, Jesse F Gregory, Donald R McCarty, Andrew D Hanson. Arabidopsis TH2 Encodes the Orphan Enzyme Thiamin Monophosphate Phosphatase.
The Plant cell.
2016 10; 28(10):2683-2696. doi:
10.1105/tpc.16.00600. [PMID: 27677881] - Vendula Bartáková, Anna Pleskačová, Katarína Kuricová, Lukáš Pácal, Veronika Dvořáková, Jana Bělobrádková, Marie Tomandlová, Josef Tomandl, Kateřina Kaňková. Dysfunctional protection against advanced glycation due to thiamine metabolism abnormalities in gestational diabetes.
Glycoconjugate journal.
2016 08; 33(4):591-8. doi:
10.1007/s10719-016-9688-9. [PMID: 27287225] - Fang Zhang, Jinit Masania, Attia Anwar, Mingzhan Xue, Daniel Zehnder, Hemali Kanji, Naila Rabbani, Paul J Thornalley. The uremic toxin oxythiamine causes functional thiamine deficiency in end-stage renal disease by inhibiting transketolase activity.
Kidney international.
2016 08; 90(2):396-403. doi:
10.1016/j.kint.2016.03.010. [PMID: 27198804] - Padmanabhan Srinivasan, Edwin C Thrower, Fred S Gorelick, Hamid M Said. Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
American journal of physiology. Gastrointestinal and liver physiology.
2016 05; 310(10):G874-83. doi:
10.1152/ajpgi.00461.2015. [PMID: 26999808] - Ghulam Hasnain, Sanja Roje, Na Sa, Rémi Zallot, Michael J Ziemak, Valérie de Crécy-Lagard, Jesse F Gregory, Andrew D Hanson. Bacterial and plant HAD enzymes catalyse a missing phosphatase step in thiamin diphosphate biosynthesis.
The Biochemical journal.
2016 Jan; 473(2):157-66. doi:
10.1042/bj20150805. [PMID: 26537753] - Daniela Hampel, Setareh Shahab-Ferdows, Linda S Adair, Margaret E Bentley, Valerie L Flax, Denise J Jamieson, Sascha R Ellington, Gerald Tegha, Charles S Chasela, Debbie Kamwendo, Lindsay H Allen. Thiamin and Riboflavin in Human Milk: Effects of Lipid-Based Nutrient Supplementation and Stage of Lactation on Vitamer Secretion and Contributions to Total Vitamin Content.
PloS one.
2016; 11(2):e0149479. doi:
10.1371/journal.pone.0149479. [PMID: 26886782] - Aparajita Banerjee, Alyssa L Preiser, Thomas D Sharkey. Engineering of Recombinant Poplar Deoxy-D-Xylulose-5-Phosphate Synthase (PtDXS) by Site-Directed Mutagenesis Improves Its Activity.
PloS one.
2016; 11(8):e0161534. doi:
10.1371/journal.pone.0161534. [PMID: 27548482] - Sondés Guedich, Barbara Puffer-Enders, Mireille Baltzinger, Guillaume Hoffmann, Cyrielle Da Veiga, Fabrice Jossinet, Stéphane Thore, Guillaume Bec, Eric Ennifar, Dominique Burnouf, Philippe Dumas. Quantitative and predictive model of kinetic regulation by E. coli TPP riboswitches.
RNA biology.
2016; 13(4):373-90. doi:
10.1080/15476286.2016.1142040. [PMID: 26932506] - Jingwen Lu, Xiaoli Pan, Guoqiang Fei, Changpeng Wang, Lei Zhao, Shaoming Sang, Huimin Liu, Meng Liu, Hui Wang, Zhiliang Wang, Chunjiu Zhong. Correlation of thiamine metabolite levels with cognitive function in the non-demented elderly.
Neuroscience bulletin.
2015 Dec; 31(6):676-84. doi:
10.1007/s12264-015-1563-3. [PMID: 26519048] - Marcus I Gibson, Edward J Brignole, Elizabeth Pierce, Mehmet Can, Stephen W Ragsdale, Catherine L Drennan. The Structure of an Oxalate Oxidoreductase Provides Insight into Microbial 2-Oxoacid Metabolism.
Biochemistry.
2015 Jul; 54(26):4112-20. doi:
10.1021/acs.biochem.5b00521. [PMID: 26061898] - Mahdi Khozaei, Stuart Fisk, Tracy Lawson, Yves Gibon, Ronan Sulpice, Mark Stitt, Stephane C Lefebvre, Christine A Raines. Overexpression of plastid transketolase in tobacco results in a thiamine auxotrophic phenotype.
The Plant cell.
2015 Feb; 27(2):432-47. doi:
10.1105/tpc.114.131011. [PMID: 25670766] - Sunita Yadav, D Swati, Hariharan Chandrasekharan. Thiamine pyrophosphate riboswitch in some representative plant species: a bioinformatics study.
Journal of computational biology : a journal of computational molecular cell biology.
2015 Jan; 22(1):1-9. doi:
10.1089/cmb.2014.0169. [PMID: 25243980] - Amber Cathie Gomersall, Huy Anh Phan, Sylvana Iacuone, Song Feng Li, Roger W Parish. The Mycoplasma hyorhinis p37 Protein Rapidly Induces Genes in Fibroblasts Associated with Inflammation and Cancer.
PloS one.
2015; 10(10):e0140753. doi:
10.1371/journal.pone.0140753. [PMID: 26512722] - Darcy McRose, Jian Guo, Adam Monier, Sebastian Sudek, Susanne Wilken, Shuangchun Yan, Thomas Mock, John M Archibald, Tadhg P Begley, Adrian Reyes-Prieto, Alexandra Z Worden. Alternatives to vitamin B1 uptake revealed with discovery of riboswitches in multiple marine eukaryotic lineages.
The ISME journal.
2014 Dec; 8(12):2517-29. doi:
10.1038/ismej.2014.146. [PMID: 25171333] - Samuel E Bocobza, Asaph Aharoni. Small molecules that interact with RNA: riboswitch-based gene control and its involvement in metabolic regulation in plants and algae.
The Plant journal : for cell and molecular biology.
2014 Aug; 79(4):693-703. doi:
10.1111/tpj.12540. [PMID: 24773387] - Paul S Hoffman, Alexandra M Bruce, Igor Olekhnovich, Cirle A Warren, Stacey L Burgess, Raquel Hontecillas, Monica Viladomiu, Josep Bassaganya-Riera, Richard L Guerrant, Timothy L Macdonald. Preclinical studies of amixicile, a systemic therapeutic developed for treatment of Clostridium difficile infections that also shows efficacy against Helicobacter pylori.
Antimicrobial agents and chemotherapy.
2014 Aug; 58(8):4703-12. doi:
10.1128/aac.03112-14. [PMID: 24890599] - Samuel G Porter, Debra Coats, Philip R Fischer, Kevanna Ou, Elizabeth L Frank, Phivan Sreang, Soksan Saing, Mark D Topazian, Felicity T Enders, Allison K Cabalka. Thiamine deficiency and cardiac dysfunction in Cambodian infants.
The Journal of pediatrics.
2014 Jun; 164(6):1456-61. doi:
10.1016/j.jpeds.2014.01.049. [PMID: 24607240] - H L Hernández-Montiel, C M Vásquez López, J G González-Loyola, G C Vega-Anaya, M E Villagrán-Herrera, M A Gallegos-Corona, C Saldaña, M Ramos Gómez, P García Horshman, P García Solís, J C Solís-S, M L Robles-Osorio, J Ávila Morales, A Varela-Echavarría, R Paredes Guerrero. Chronic administration of thiamine pyrophosphate decreases age-related histological atrophic testicular changes and improves sexual behavior in male Wistar rats.
Histology and histopathology.
2014 Jun; 29(6):785-95. doi:
10.14670/hh-29.785. [PMID: 24371036] - Katherine Deigan Warner, Philip Homan, Kevin M Weeks, Alison G Smith, Chris Abell, Adrian R Ferré-D'Amaré. Validating fragment-based drug discovery for biological RNAs: lead fragments bind and remodel the TPP riboswitch specifically.
Chemistry & biology.
2014 May; 21(5):591-5. doi:
10.1016/j.chembiol.2014.03.007. [PMID: 24768306] - Mehmet Ibrahim Turan, Huseyin Tan, Nihal Cetin, Halis Suleyman, Atilla Cayir. Effects of thiamine and thiamine pyrophosphate on epileptic episode model established with caffeine in rats.
Epilepsy research.
2014 Mar; 108(3):405-10. doi:
10.1016/j.eplepsyres.2013.12.006. [PMID: 24434003] - Svetlana M Nabokina, Katsuhisa Inoue, Veedamali S Subramanian, Judith E Valle, Hiroaki Yuasa, Hamid M Said. Molecular identification and functional characterization of the human colonic thiamine pyrophosphate transporter.
The Journal of biological chemistry.
2014 Feb; 289(7):4405-16. doi:
10.1074/jbc.m113.528257. [PMID: 24379411] - M I Turan, A Cayir, N Cetin, H Suleyman, I Siltelioglu Turan, H Tan. An investigation of the effect of thiamine pyrophosphate on cisplatin-induced oxidative stress and DNA damage in rat brain tissue compared with thiamine: thiamine and thiamine pyrophosphate effects on cisplatin neurotoxicity.
Human & experimental toxicology.
2014 Jan; 33(1):14-21. doi:
10.1177/0960327113485251. [PMID: 23632005] - Aymeric Goyer, Ghulam Hasnain, Océane Frelin, Maria A Ralat, Jesse F Gregory, Andrew D Hanson. A cross-kingdom Nudix enzyme that pre-empts damage in thiamin metabolism.
The Biochemical journal.
2013 Sep; 454(3):533-42. doi:
10.1042/bj20130516. [PMID: 23834287] - Michael Moulin, Ginnie T D T Nguyen, Mark A Scaife, Alison G Smith, Teresa B Fitzpatrick. Analysis of Chlamydomonas thiamin metabolism in vivo reveals riboswitch plasticity.
Proceedings of the National Academy of Sciences of the United States of America.
2013 Sep; 110(36):14622-7. doi:
10.1073/pnas.1307741110. [PMID: 23959877] - Ismail Demiryilmaz, Ebru Sener, Nihal Cetin, Durdu Altuner, Fatih Akcay, Halis Suleyman. A comparative investigation of biochemical and histopathological effects of thiamine and thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat ovarian tissue.
Archives of pharmacal research.
2013 Sep; 36(9):1133-9. doi:
10.1007/s12272-013-0173-8. [PMID: 23760618] - Debra Coats, Elizabeth L Frank, Joel M Reid, Kevanna Ou, Mary Chea, Mengkheang Khin, Chiva Preou, Felicity T Enders, Philip R Fischer, Mark Topazian. Thiamine pharmacokinetics in Cambodian mothers and their breastfed infants.
The American journal of clinical nutrition.
2013 Sep; 98(3):839-44. doi:
10.3945/ajcn.113.062737. [PMID: 23864540] - Durdu Altuner, Nihal Cetin, Bahadir Suleyman, Zeynep Aslan, Ahmet Hacimuftuoglu, Mine Gulaboglu, Neslihan Isaoglu, Ismail Demiryilmaz, Halis Suleyman. Effect of thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat kidney.
Indian journal of pharmacology.
2013 Jul; 45(4):339-43. doi:
10.4103/0253-7613.115005. [PMID: 24014907] - Aparajita Banerjee, Yan Wu, Rahul Banerjee, Yue Li, Honggao Yan, Thomas D Sharkey. Feedback inhibition of deoxy-D-xylulose-5-phosphate synthase regulates the methylerythritol 4-phosphate pathway.
The Journal of biological chemistry.
2013 Jun; 288(23):16926-16936. doi:
10.1074/jbc.m113.464636. [PMID: 23612965] - E Cetin, S Civelek, G Andican, F Candan Polizzi, V Yumuk, G Burçak. Plasma AGE-peptides and C-peptide in early-stage diabetic nephropathy patients on thiamine and pyridoxine therapy.
Minerva medica.
2013 Feb; 104(1):93-101. doi:
NULL. [PMID: 23392542] - Robert van Lis, Carole Baffert, Yohann Couté, Wolfgang Nitschke, Ariane Atteia. Chlamydomonas reinhardtii chloroplasts contain a homodimeric pyruvate:ferredoxin oxidoreductase that functions with FDX1.
Plant physiology.
2013 Jan; 161(1):57-71. doi:
10.1104/pp.112.208181. [PMID: 23154536] - Mehmet Ibrahim Turan, Isil Siltelioglu Turan, Renad Mammadov, Konca Altınkaynak, Abdullah Kisaoglu. The effect of thiamine and thiamine pyrophosphate on oxidative liver damage induced in rats with cisplatin.
BioMed research international.
2013; 2013(?):783809. doi:
10.1155/2013/783809. [PMID: 23841092] - Samuel E Bocobza, Sergey Malitsky, Wagner L Araújo, Adriano Nunes-Nesi, Sagit Meir, Michal Shapira, Alisdair R Fernie, Asaph Aharoni. Orchestration of thiamin biosynthesis and central metabolism by combined action of the thiamin pyrophosphate riboswitch and the circadian clock in Arabidopsis.
The Plant cell.
2013 Jan; 25(1):288-307. doi:
10.1105/tpc.112.106385. [PMID: 23341335] - Debra Coats, Kelsey Shelton-Dodge, Kevanna Ou, Vannara Khun, Sommon Seab, Kimsan Sok, Chiva Prou, Silvia Tortorelli, Thomas P Moyer, Lisa E Cooper, Tadhg P Begley, Felicity Enders, Philip R Fischer, Mark Topazian. Thiamine deficiency in Cambodian infants with and without beriberi.
The Journal of pediatrics.
2012 Nov; 161(5):843-7. doi:
10.1016/j.jpeds.2012.05.006. [PMID: 22703952] - Océane Frelin, Gennaro Agrimi, Valentina L Laera, Alessandra Castegna, Lynn G L Richardson, Robert T Mullen, Claudia Lerma-Ortiz, Ferdinando Palmieri, Andrew D Hanson. Identification of mitochondrial thiamin diphosphate carriers from Arabidopsis and maize.
Functional & integrative genomics.
2012 Jun; 12(2):317-26. doi:
10.1007/s10142-012-0273-4. [PMID: 22426856] - Sławomir Michalak, Tomasz Piorunek, Danuta Lenart-Jankowska, Krystyna Osztynowicz, Wojciech Kozubski. [Anti-heat shock protein 70 (anti - Hsp 70) antibodies in alcohol use disorder patients].
Przeglad lekarski.
2012; 69(10):781-4. doi:
. [PMID: 23421033] - Mark E Obrenovich, Raymond J Shamberger, Derrick Lonsdale. Altered heavy metals and transketolase found in autistic spectrum disorder.
Biological trace element research.
2011 Dec; 144(1-3):475-86. doi:
10.1007/s12011-011-9146-2. [PMID: 21755304] - Martina Krautwald, Dale Leech, Stacey Horne, Megan L Steele, Josephine Forbes, Anton Rahmadi, Renate Griffith, Gerald Münch. The advanced glycation end product-lowering agent ALT-711 is a low-affinity inhibitor of thiamine diphosphokinase.
Rejuvenation research.
2011 Aug; 14(4):383-91. doi:
10.1089/rej.2010.1143. [PMID: 21612515] - Weina Zhao, Xudong Cheng, Zongan Huang, Huajie Fan, Huilan Wu, Hong-Qing Ling. Tomato LeTHIC is an Fe-requiring HMP-P synthase involved in thiamine synthesis and regulated by multiple factors.
Plant & cell physiology.
2011 Jun; 52(6):967-82. doi:
10.1093/pcp/pcr048. [PMID: 21511719] - Xuhui Niu, Xiang Liu, Yanfei Zhou, Congwei Niu, Zhen Xi, Xiao-Dong Su. Preliminary X-ray crystallographic studies of the catalytic subunit of Escherichia coli AHAS II with its cofactors.
Acta crystallographica. Section F, Structural biology and crystallization communications.
2011 Jun; 67(Pt 6):659-61. doi:
10.1107/s1744309111008839. [PMID: 21636904] - Susana Alcázar-Leyva, Noé Alvarado-Vásquez. Could thiamine pyrophosphate be a regulator of the nitric oxide synthesis in the endothelial cell of diabetic patients?.
Medical hypotheses.
2011 May; 76(5):629-31. doi:
10.1016/j.mehy.2011.01.015. [PMID: 21288652] - Danilo Meyer, Piotr Neumann, Christoph Parthier, Rudolf Friedemann, Natalia Nemeria, Frank Jordan, Kai Tittmann. Double duty for a conserved glutamate in pyruvate decarboxylase: evidence of the participation in stereoelectronically controlled decarboxylation and in protonation of the nascent carbanion/enamine intermediate.
Biochemistry.
2010 Sep; 49(37):8197-212. doi:
10.1021/bi100828r. [PMID: 20715795] - B Renee Bozard, Preethi S Ganapathy, Jennifer Duplantier, Barbara Mysona, Yonju Ha, Penny Roon, Robert Smith, I David Goldman, Puttur Prasad, Pamela M Martin, Vadivel Ganapathy, Sylvia B Smith. Molecular and biochemical characterization of folate transport proteins in retinal Müller cells.
Investigative ophthalmology & visual science.
2010 Jun; 51(6):3226-35. doi:
10.1167/iovs.09-4833. [PMID: 20053979] - Sergio Torres, Hermelinda Salgado-Ceballos, José Luis Torres, Sandra Orozco-Suarez, Araceli Díaz-Ruíz, Angelina Martínez, Mario Rivera-Cruz, Camilo Ríos, Alicia Lara, Carlos Collado, Gabriel Guizar-Sahagún. Early metabolic reactivation versus antioxidant therapy after a traumatic spinal cord injury in adult rats.
Neuropathology : official journal of the Japanese Society of Neuropathology.
2010 Feb; 30(1):36-43. doi:
10.1111/j.1440-1789.2009.01037.x. [PMID: 19563509] - Iu M Parkhomenko, A A Strokina, S Iu Pilipchuk, S P Stepanenko, L I Chekhovskaia, G V Donchenko. [Existence of two different active sites on thiamine binding protein in plasma membranes of synaptosomes].
Ukrains'kyi biokhimichnyi zhurnal (1999 ).
2010 Jan; 82(1):34-41. doi:
. [PMID: 20684226] - S Torres, H Salgado-Ceballos, G Guizar-Sahagún, J L Torres, S Orozco-Suarez, A Diaz-Ruiz, M E Vázquez, C Collado, C Ríos. Deleterious versus neuroprotective effect of metabolic inhibition after traumatic spinal cord injury.
Spinal cord.
2009 Oct; 47(10):745-50. doi:
10.1038/sc.2009.27. [PMID: 19488053] - Michel Frédérich, David Delvaux, Tiziana Gigliobianco, Marjorie Gangolf, Georges Dive, Gabriel Mazzucchelli, Benjamin Elias, Edwin De Pauw, Luc Angenot, Pierre Wins, Lucien Bettendorff. Thiaminylated adenine nucleotides. Chemical synthesis, structural characterization and natural occurrence.
The FEBS journal.
2009 Jun; 276(12):3256-68. doi:
10.1111/j.1742-4658.2009.07040.x. [PMID: 19438713] - Maria Rapala-Kozik, Anna Gołda, Marta Kujda. Enzymes that control the thiamine diphosphate pool in plant tissues. Properties of thiamine pyrophosphokinase and thiamine-(di)phosphate phosphatase purified from Zea mays seedlings.
Plant physiology and biochemistry : PPB.
2009 Apr; 47(4):237-42. doi:
10.1016/j.plaphy.2008.12.015. [PMID: 19167902] - V M Bautista-Hernández, R López-Ascencio, M Del Toro-Equihua, C Vásquez. Effect of thiamine pyrophosphate on levels of serum lactate, maximum oxygen consumption and heart rate in athletes performing aerobic activity.
The Journal of international medical research.
2008 Nov; 36(6):1220-6. doi:
10.1177/147323000803600608. [PMID: 19094430] - Samuel E Bocobza, Asaph Aharoni. Switching the light on plant riboswitches.
Trends in plant science.
2008 Oct; 13(10):526-33. doi:
10.1016/j.tplants.2008.07.004. [PMID: 18778966] - Iu M Parkhomenko, S Iu Pilipchuk, A A Sidorova, S P Stepanenko, L I Chekhovskaia, G V Donchenko. [Thiamine metabolism disorders in the rat brain in experimental alcoholism and a possibility of their correction by vitamin E].
Ukrains'kyi biokhimichnyi zhurnal (1999 ).
2008 Jul; 80(4):96-104. doi:
. [PMID: 19140455] - S Bäckermann, C Poel, W Ternes. Thiamin phosphates in egg yolk granules and plasma of regular and embryonated eggs of hens and in five- and seven-day-old embryos.
Poultry science.
2008 Jan; 87(1):108-15. doi:
10.3382/ps.2007-00158. [PMID: 18079459] - Wim Versées, Stijn Spaepen, Martin D H Wood, Finian J Leeper, Jos Vanderleyden, Jan Steyaert. Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase.
The Journal of biological chemistry.
2007 Nov; 282(48):35269-78. doi:
10.1074/jbc.m706048200. [PMID: 17905741] - Samuel Bocobza, Avital Adato, Tali Mandel, Michal Shapira, Evgeny Nudler, Asaph Aharoni. Riboswitch-dependent gene regulation and its evolution in the plant kingdom.
Genes & development.
2007 Nov; 21(22):2874-9. doi:
10.1101/gad.443907. [PMID: 18006684] - Andreas Wachter, Meral Tunc-Ozdemir, Beth C Grove, Pamela J Green, David K Shintani, Ronald R Breaker. Riboswitch control of gene expression in plants by splicing and alternative 3' end processing of mRNAs.
The Plant cell.
2007 Nov; 19(11):3437-50. doi:
10.1105/tpc.107.053645. [PMID: 17993623] - P J Thornalley, R Babaei-Jadidi, H Al Ali, N Rabbani, A Antonysunil, J Larkin, A Ahmed, G Rayman, C W Bodmer. High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease.
Diabetologia.
2007 Oct; 50(10):2164-70. doi:
10.1007/s00125-007-0771-4. [PMID: 17676306] - F Batifoulier, M A Verny, C Besson, E Chanliaud, C Rémésy, C Demigné. Restoration of thiamine status with white or whole wheat bread in a thiamine-depleted rat model.
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition.
2007 Jan; 77(1):46-56. doi:
10.1024/0300-9831.77.1.46. [PMID: 17685095] - Eun-Ha Lee, Mi-Sun Ahn, Jin-Soon Hwang, Kyung-Hwa Ryu, Sun-Jun Kim, Sung-Hwan Kim. A Korean female patient with thiamine-responsive pyruvate dehydrogenase complex deficiency due to a novel point mutation (Y161C)in the PDHA1 gene.
Journal of Korean medical science.
2006 Oct; 21(5):800-4. doi:
10.3346/jkms.2006.21.5.800. [PMID: 17043409] - Stéphane Thore, Marc Leibundgut, Nenad Ban. Structure of the eukaryotic thiamine pyrophosphate riboswitch with its regulatory ligand.
Science (New York, N.Y.).
2006 May; 312(5777):1208-11. doi:
10.1126/science.1128451. [PMID: 16675665] - Tara Quasim, Donald C McMillan, Dinesh Talwar, Aikaterina Vasilaki, Denis St J O'Reilly, John Kinsella. The relationship between plasma and red cell B-vitamin concentrations in critically-ill patients.
Clinical nutrition (Edinburgh, Scotland).
2005 Dec; 24(6):956-60. doi:
10.1016/j.clnu.2005.06.004. [PMID: 16054730] - Veerle Foulon, Mieke Sniekers, Els Huysmans, Stanny Asselberghs, Vincent Mahieu, Guy P Mannaerts, Paul P Van Veldhoven, Minne Casteels. Breakdown of 2-hydroxylated straight chain fatty acids via peroxisomal 2-hydroxyphytanoyl-CoA lyase: a revised pathway for the alpha-oxidation of straight chain fatty acids.
The Journal of biological chemistry.
2005 Mar; 280(11):9802-12. doi:
10.1074/jbc.m413362200. [PMID: 15644336] - Khanh Vinh Quoc Luong, Lan Thi Hoang Nguyen. Adult hypophosphatasia and a low level of red blood cell thiamine pyrophosphate.
Annals of nutrition & metabolism.
2005 Mar; 49(2):107-9. doi:
10.1159/000084743. [PMID: 15802905] - F Batifoulier, M-A Verny, C Besson, C Demigné, C Rémésy. Determination of thiamine and its phosphate esters in rat tissues analyzed as thiochromes on a RP-amide C16 column.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2005 Feb; 816(1-2):67-72. doi:
10.1016/j.jchromb.2004.11.004. [PMID: 15664335] - Jennifer A McCourt, Siew Siew Pang, Luke W Guddat, Ronald G Duggleby. Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase.
Biochemistry.
2005 Feb; 44(7):2330-8. doi:
10.1021/bi047980a. [PMID: 15709745] - Hiroshi Ihara, Takayuki Matsumoto, Yoshio Shino, Naotaka Hashizume. Assay values for thiamine or thiamine phosphate esters in whole blood do not depend on the anticoagulant used.
Journal of clinical laboratory analysis.
2005; 19(5):205-8. doi:
10.1002/jcla.20079. [PMID: 16170809] - N E Petushok, B G Petushok, M A El'chaninova, A A Ban'kovskiĭ, R V Trebukhina. [Functional activity of blood and liver cells under formaldehyde intoxication via inhalation].
Biomeditsinskaia khimiia.
2005; 51(1):76-80. doi:
". [PMID: 15850223] - Joungmok Kim, Dong-Gil Beak, Young-Tae Kim, Jung-Do Choi, Moon-Young Yoon. Effects of deletions at the C-terminus of tobacco acetohydroxyacid synthase on the enzyme activity and cofactor binding.
The Biochemical journal.
2004 Nov; 384(Pt 1):59-68. doi:
10.1042/bj20040427. [PMID: 15521822] - Andrew Gray, Donald C McMillan, Chris Wilson, Cathy Williamson, Denis St J O'Reilly, Dinesh Talwar. The relationship between plasma and red cell concentrations of vitamins thiamine diphosphate, flavin adenine dinucleotide and pyridoxal 5-phosphate following elective knee arthroplasty.
Clinical nutrition (Edinburgh, Scotland).
2004 Oct; 23(5):1080-3. doi:
10.1016/j.clnu.2004.01.013. [PMID: 15380899] - Liesbeth de Jong, Yan Meng, Joseph Dent, Siegfried Hekimi. Thiamine pyrophosphate biosynthesis and transport in the nematode Caenorhabditis elegans.
Genetics.
2004 Oct; 168(2):845-54. doi:
10.1534/genetics.104.028605. [PMID: 15514058] - Marina V Kovina, Aart De Kok, Irina A Sevostyanova, Ludmila S Khailova, Natalya V Belkina, German A Kochetov. The molecular origin of the thiamine diphosphate-induced spectral bands of ThDP-dependent enzymes.
Proteins.
2004 Aug; 56(2):338-45. doi:
10.1002/prot.20115. [PMID: 15211516] - C Patrini, A Griziotti, L Ricciardi. Obese individuals as thiamin storers.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.
2004 Jul; 28(7):920-4. doi:
10.1038/sj.ijo.0802638. [PMID: 15098017] - Jacinta L Chuang, R Max Wynn, Clint C Moss, Jiu-Li Song, Jun Li, Nibal Awad, Hanna Mandel, David T Chuang. Structural and biochemical basis for novel mutations in homozygous Israeli maple syrup urine disease patients: a proposed mechanism for the thiamin-responsive phenotype.
The Journal of biological chemistry.
2004 Apr; 279(17):17792-800. doi:
10.1074/jbc.m313879200. [PMID: 14742428] - Anna Gołda, Piotr Szyniarowski, Katarzyna Ostrowska, Andrzej Kozik, Maria Rapała-Kozik. Thiamine binding and metabolism in germinating seeds of selected cereals and legumes.
Plant physiology and biochemistry : PPB.
2004 Mar; 42(3):187-95. doi:
10.1016/j.plaphy.2004.01.002. [PMID: 15051042] - G Rindi, C Patrini, A Nauti, R Bellazzi, P Magni. Three thiamine analogues differently alter thiamine transport and metabolism in nervous tissue: an in vivo kinetic study using rats.
Metabolic brain disease.
2003 Dec; 18(4):245-63. doi:
10.1023/b:mebr.0000020187.98238.58. [PMID: 15128183] - Conceição Calhau, Fátima Martel, Cândido Hipólito-Reis, Isabel Azevedo. Effect of thiamine on 3H-MPP+ uptake by Caco-2 cells.
Pharmacological research.
2003 Dec; 48(6):579-84. doi:
10.1016/s1043-6618(03)00176-2. [PMID: 14527822] - Stefan Gerhardt, Stefanie Echt, Marco Busch, Jörg Freigang, Günter Auerbach, Gerd Bader, William F Martin, Adelbert Bacher, Robert Huber, Markus Fischer. Structure and properties of an engineered transketolase from maize.
Plant physiology.
2003 Aug; 132(4):1941-9. doi:
10.1104/pp.103.020982. [PMID: 12913150] - Narasimhan Sudarsan, Jeffrey E Barrick, Ronald R Breaker. Metabolite-binding RNA domains are present in the genes of eukaryotes.
RNA (New York, N.Y.).
2003 Jun; 9(6):644-7. doi:
10.1261/rna.5090103. [PMID: 12756322] - Anja Schütz, Tatyana Sandalova, Stefano Ricagno, Gerhard Hübner, Stephan König, Gunter Schneider. Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid.
European journal of biochemistry.
2003 May; 270(10):2312-21. doi:
10.1046/j.1432-1033.2003.03601.x. [PMID: 12752451] - J Drewe, F Delco, T Kissel, C Beglinger. Effect of intravenous infusions of thiamine on the disposition kinetics of thiamine and its pyrophosphate.
Journal of clinical pharmacy and therapeutics.
2003 Feb; 28(1):47-51. doi:
10.1046/j.1365-2710.2003.00462.x. [PMID: 12605618] - J A Molina, F J Jiménez-Jiménez, A Hernánz, E Fernández-Vivancos, S Medina, F de Bustos, C Gómez-Escalonilla, Y Sayed. Cerebrospinal fluid levels of thiamine in patients with Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996).
2002 Jul; 109(7-8):1035-44. doi:
10.1007/s007020200087. [PMID: 12111441]