Rhodamine_B (BioDeep_00000000560)

   

Volatile Flavor Compounds


代谢物信息卡片


Ethanaminium, N-(9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)-N-e- thyl-, chloride

化学式: C28H31N2O3.Cl (478.2023086)
中文名称: 罗丹明B
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCN(CC)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](CC)CC)C=C3O2)C4=CC=CC=C4C(=O)O.[Cl-]
InChI: 1H

描述信息

C.i. food red 15 appears as green crystals or reddish-violet powder. Used as a dye, especially for paper, as a metal chelating reagent, and in drugs and cosmetics.
Rhodamine B is an organic chloride salt having N-[9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene]-N-ethylethanaminium as the counterion. An amphoteric dye commonly used as a fluorochrome. It has a role as a fluorochrome, a fluorescent probe and a histological dye. It is an organic chloride salt and a xanthene dye. It contains a rhodamine B(1+).
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D012235 - Rhodamines
D004396 - Coloring Agents > D005456 - Fluorescent Dyes

同义名列表

122 个代谢物同义名

Ethanaminium, N-(9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)-N-e- thyl-, chloride; Ethanaminium, N-(9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)-N-e-thyl-, chloride; Ethanaminium, N-(9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)-N-ethyl-, chloride; Ethanaminium, N-[9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene]-N-ethyl-, chloride; Ethanaminium, N-(9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)-N-ethyl-,chloride; N-(9-(2-Carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)-N-e- thylethanaminium chloride; N-(9-(2-Carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)-N-e-thylethanaminium chloride; N-[9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene]-N-ethylethanaminium chloride; N-(9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)-N-ethylethanaminium chloride; Ammonium, (9-(o-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)diethyl-, chloride; (9-(o-Carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene) diethylammonium chloride; [9-(o-Carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene] diethylammonium chloride; Ethanaminium, N-(9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)-N-ethyl-; [9-(2-carboxyphenyl)-6-(diethylamino)xanthen-3-ylidene]-diethylazanium;chloride; Xanthylium, 9-(2-carboxyphenyl)-3,6-bis(diethylamino)-, chloride (1:1), dimer; 9-O-Carboxyphenyl-6-diethylamino-3-ethylimino-3-isoxanthene, 3-ethochloride; Xanthylium, 9-(2-carboxyphenyl)-3,6-bis(diethylamino)-, chloride (1:1); Basic Violet 10;Brilliant Pink B;Rhodamine O;Tetraethylrhodamine; Xanthylium, 9-(2-carboxyphenyl)-3,6-bis(diethylamino)-, chloride; 9-(2-carboxyphenyl)-3,6-bis(diethylamino) xanthylium chloride; 9-(2-carboxyphenyl)-3,6-bis(diethylamino)xanthenium chloride; 9-(2-Carboxyphenyl)-3,6-bis(diethylamino)xanthylium chloride; 9-(2-Carboxyphenyl)-3,6-bis(diethylamino)xanthyliumchloride; TETRAETHYLDIAMINO-O-CARBOXY-PHENYL-XANTHENYL CHLORIDE; Tetraethyldiamino-o-carboxyphenyl xanthenyl chloride; DIETHYL-M-AMINO-PHENOLPHTHALEIN HYDROCHLORIDE; Diethyl-m-aminophenolphthalein hydrochloride; Cosmetic Brilliant Pink Bluish D conc; FD&C RED NO. 19 (DELISTED) (II); FD&C RED NO. 19 (DELISTED) [II]; D&C RED NO. 19 (DELISTED) (II); D&C RED NO. 19 (DELISTED) [II]; PYWVYCXTNDRMGF-UHFFFAOYSA-N; Symulex Rhodamine B Toner F; Violet zasadita 10 [Czech]; FD&C RED NO. 19 (DELISTED); D&C RED NO. 19 (DELISTED); Hexacol Rhodamine B Extra; Calcozine Rhodamine BXP; Calcozine Rhodamine BX; Rhodamine, tetraethyl-; Calcozine Rhodamine BL; BASIC VIOLET 10 [INCI]; Rhodamine S [Russian]; Rhodamine, Blue shade; Acid Brilliant Pink B; rhodamine B dihydride; C.I. Basic Violet 10; Edicol Supra Rose BS; Rhodamine Lake Red B; Diabasic Rhodamine B; Elcozine Rhodamine B; rhodamine B chloride; Edicol Suppa Rose BS; Certiqual Rhodamine; FD and C Red No. 19; Rhodamine B Extra S; Rhodamine BA Export; Mitsui Rhodamine BX; Edicol Supra Rose B; tetraethylrhodamine; Akiriku Rhodamine B; rhodamine B acetate; Eriosin Rhodamine B; Takaoka Rhodamine B; Aizen Rhodamine BHC; Rhodamine B 20-7470; Violet zasadita 10; RHODAMINE B [HSDB]; CI Basic Violet 10; D and C Red No. 19; FD AND C RED NO 19; RHODAMINE B [IARC]; Aizen Rhodamine BH; RHODAMINE B (IARC); Rhodamine B Extra; Symulex Magenta F; D AND C RED NO 19; Ikada Rhodamine B; Calcozine Red BX; Brilliant Pink B; RHODAMINE B [MI]; C.I. Food Red 15; D & C Red No. 19; Geranium lake N; Basazol Red 71P; FD&C Red No. 19; Basic Violet 10; ADC Rhodamine B; UNII-K7G5SCF8IL; D & C Red No.19; Rhodamine FB CL; Basic Rose Red; Iragen Red L-U; CI Food Red 15; Symulex Pink F; D&C Red No. 19; Rhodamine BXP; D+C RED NO 19; Rhodamine BXL; D&C red no.19; Rhodamine BA; Tox21_301450; Rhodamine FB; Rhodamine BF; Rhodamine BS; Rhodamine BN; Rhodamine BL; Rhodamine BX; Food Red 15; Rhodamine S; Rhodamine B; Rhodamine?B; Rhodamine O; CAS-81-88-9; D&C Red 19; K7G5SCF8IL; Rodamina B; RhodamineB; Rheonine B; Rhodamine; Rhodamine B



数据库引用编号

14 个数据库交叉引用编号

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yuerong Qian, Xuchao Wei, Yiwei Wang, Shaoping Yin, Jun Chen, Jie Dong. Development of a novel human stratum corneum mimetic phospholipid -vesicle-based permeation assay models for in vitro permeation studies. Drug development and industrial pharmacy. 2024 May; 50(5):410-419. doi: 10.1080/03639045.2024.2331242. [PMID: 38497274]
  • Shereen A Sabry, Amal M Abd El Razek, Mohamed Nabil, Shaimaa M Khedr, Hanan M El-Nahas, Noura G Eissa. Brain-targeted delivery of Valsartan using solid lipid nanoparticles labeled with Rhodamine B; a promising technique for mitigating the negative effects of stroke. Drug delivery. 2023 Dec; 30(1):2179127. doi: 10.1080/10717544.2023.2179127. [PMID: 36794404]
  • Subramaninan Ramanathan, Jitti Kasemchainan, Ho-Chiao Chuang, Abílio J F N Sobral, Sirilux Poompradub. Rhodamine B dye degradation using used face masks-derived carbon coupled with peroxymonosulfate. Environmental pollution (Barking, Essex : 1987). 2023 Mar; 324(?):121386. doi: 10.1016/j.envpol.2023.121386. [PMID: 36868547]
  • B Harikumar, Mohammad K Okla, Ibrahim A Alaraidh, Asmaa Mohebaldin, Walid Soufan, Mostafa A Abdel-Maksoud, Mohammed Aufy, Ajith M Thomas, Lija L Raju, S Sudheer Khan. Robust visible light active CoNiO2-BiFeO3-NiS ternary nanocomposite for photo-fenton degradation of rhodamine B and methyl orange: Kinetics, degradation pathway and toxicity assessment. Journal of environmental management. 2022 Sep; 317(?):115321. doi: 10.1016/j.jenvman.2022.115321. [PMID: 35751232]
  • Chen-Chen Bai, Meng-Ying Chen, Tai-Cheng Zhou, Ruo-Lin Jiang, Lin-Yi Dong, Hua-Wei Wei, Xiang-Jin Kong, Xian-Hua Wang. Hydrophilic rhodamine B-loaded / boronic acid-modified graphene oxide nanocomposite as a substitute of enzyme-labeled second antibody for ultrasensitive detection of antibodies. Journal of pharmaceutical and biomedical analysis. 2022 Jul; 216(?):114804. doi: 10.1016/j.jpba.2022.114804. [PMID: 35490506]
  • Xin Zhan, Xiaoxiao Yu, Benmengyang Li, Rui Zhou, Qingyu Fang, Yiwei Wu. Quantifying H2O2 by ratiometric fluorescence sensor platform of N-GQDs/rhodamine B in the presence of thioglycolic acid under the catalysis of Fe3. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2022 Jul; 275(?):121191. doi: 10.1016/j.saa.2022.121191. [PMID: 35366522]
  • S Balasurya, Mohammad K Okla, Asmaa Mohebaldin, Abdullah A Al-Ghamdi, Mostafa A Abdel-Maksoud, Bander Almunqedhi, Hamada AbdElgawad, Ajith M Thomas, Lija L Raju, S Sudheer Khan. Self-assembling of 3D layered flower architecture of BiOI modified MgCr2O4 nanosphere for wider spectrum visible-light photocatalytic degradation of rhodamine B and malachite green: Mechanism, pathway, reactive sites and toxicity prediction. Journal of environmental management. 2022 Apr; 308(?):114614. doi: 10.1016/j.jenvman.2022.114614. [PMID: 35121463]
  • Qiang Chen, Bing Wan, Paijin Zhu, Shuxia Xu, Yi Huang. The synergy of adsorption and photosensitization of platinum-doped graphitic carbon nitride for improved removal of rhodamine B. Environmental science and pollution research international. 2022 Mar; 29(11):16449-16459. doi: 10.1007/s11356-021-15340-0. [PMID: 34651272]
  • Ismael Otri, Serena Medaglia, Elena Aznar, Félix Sancenón, Ramón Martínez-Máñez. Fluorogenic Detection of Human Serum Albumin Using Curcumin-Capped Mesoporous Silica Nanoparticles. Molecules (Basel, Switzerland). 2022 Feb; 27(3):. doi: 10.3390/molecules27031133. [PMID: 35164400]
  • Abdullah Khaled Al-Buriahi, Adel Ali Al-Gheethi, Ponnusamy Senthil Kumar, Radin Maya Saphira Radin Mohamed, Hanita Yusof, Abdullah Faisal Alshalif, Nasradeen A Khalifa. Elimination of rhodamine B from textile wastewater using nanoparticle photocatalysts: A review for sustainable approaches. Chemosphere. 2022 Jan; 287(Pt 2):132162. doi: 10.1016/j.chemosphere.2021.132162. [PMID: 34826899]
  • K S Trosheva, S A Sorokina, А А Efimova, P I Semenyuk, A K Berkovich, A A Yaroslavov, Z B Shifrina. Interaction of multicomponent anionic liposomes with cationic pyridylphenylene dendrimer: Does the complex behavior depend on the liposome composition?. Biochimica et biophysica acta. Biomembranes. 2021 12; 1863(12):183761. doi: 10.1016/j.bbamem.2021.183761. [PMID: 34480877]
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  • Md Rizwanullah, Ahmad Perwez, Showkat Rasool Mir, Mohd Moshahid Alam Rizvi, Saima Amin. Exemestane encapsulated polymer-lipid hybrid nanoparticles for improved efficacy against breast cancer: optimization,in vitrocharacterization and cell culture studies. Nanotechnology. 2021 Jul; 32(41):. doi: 10.1088/1361-6528/ac1098. [PMID: 34198267]
  • Maria Alice de Oliveira, Gwenaelle Pound-Lana, Patricia Capelari-Oliveira, Thaís Godinho Pontífice, Sabrina Emanuelle Dias Silva, Marina Guimarães Carvalho Machado, Bruna Bueno Postacchini, Vanessa Carla Furtado Mosqueira. Release, transfer and partition of fluorescent dyes from polymeric nanocarriers to serum proteins monitored by asymmetric flow field-flow fractionation. Journal of chromatography. A. 2021 Mar; 1641(?):461959. doi: 10.1016/j.chroma.2021.461959. [PMID: 33611111]
  • Keding Li, Yuqing Lei, Jun Liao, Yong Zhang. A facile synthesis of graphene oxide/locust bean gum hybrid aerogel for water purification. Carbohydrate polymers. 2021 Feb; 254(?):117318. doi: 10.1016/j.carbpol.2020.117318. [PMID: 33357881]
  • Zitong Qi, Cuiping Jiang, Hai Gao, Yanyan Wang, Qiqi Zhang, Wenli Zhang, Jianping Liu. Endocytic recycling as cellular trafficking fate of simvastatin-loaded discoidal reconstituted high-density lipoprotein to coordinate cholesterol efflux and drug influx. Nanomedicine : nanotechnology, biology, and medicine. 2021 02; 32(?):102323. doi: 10.1016/j.nano.2020.102323. [PMID: 33186693]
  • Qi-Xuan Sun, Xing Wei, Shang-Qing Zhang, Ming-Li Chen, Ting Yang, Yong-Liang Yu, Jian-Hua Wang. Dual-mode imaging of copper transporter 1 in HepG2 cells by hyphenating confocal laser scanning microscopy with laser ablation ICPMS. Analytical and bioanalytical chemistry. 2021 Feb; 413(5):1353-1361. doi: 10.1007/s00216-020-03097-3. [PMID: 33404748]
  • Baicun Li, Yinhe Sun, Jing Lu, Xin Peng. Investigation on the binding interaction of rhodamine B with human serum albumin: effect of metal ions. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2021; 56(3):259-271. doi: 10.1080/03601234.2021.1873030. [PMID: 33459173]
  • Min Yuan, Xinxi Fu, Jing Yu, Yan Xu, Jiale Huang, Qingbiao Li, Daohua Sun. Green synthesized iron nanoparticles as highly efficient fenton-like catalyst for degradation of dyes. Chemosphere. 2020 Dec; 261(?):127618. doi: 10.1016/j.chemosphere.2020.127618. [PMID: 32707320]
  • Man Li, Lan Yuan, Yingying Chen, Wenxiao Ma, Fuxiang Ran, Lihe Zhang, Demin Zhou, Sulong Xiao. Rhodamine B-based fluorescent probes for molecular mechanism study of the anti-influenza activity of pentacyclic triterpenes. European journal of medicinal chemistry. 2020 Nov; 205(?):112664. doi: 10.1016/j.ejmech.2020.112664. [PMID: 32755747]
  • Beryl Vedha Yesudhason, Johnson Retnaraj Samuel Selvan Christyraj, Mijithra Ganesan, Karthikeyan Subbiahanadar Chelladurai, Saravanakumar Venkatachalam, Arun Ramalingam, Johnson Benedict, Vennila Devi Paulraj, Jackson Durairaj Selvan Christyraj. Developmental stages of zebrafish (Danio rerio) embryos and toxicological studies using foldscope microscope. Cell biology international. 2020 Oct; 44(10):1968-1980. doi: 10.1002/cbin.11412. [PMID: 32584484]
  • Wenying He, Rongqiang Liu, Yuanhao Liao, Guohua Ding, Jianling Li, Wei Liu, Luyong Wu, Huajie Feng, Zaifeng Shi, Mengxiong He. A new 1,2,3-triazole and its rhodamine B derivatives as a fluorescence probe for mercury ions. Analytical biochemistry. 2020 06; 598(?):113690. doi: 10.1016/j.ab.2020.113690. [PMID: 32259511]
  • Mohammad F Bostanudin, Aikaterini Lalatsa, Dariusz C Górecki, Eugen Barbu. Engineering butylglyceryl-modified polysaccharides towards nanomedicines for brain drug delivery. Carbohydrate polymers. 2020 May; 236(?):116060. doi: 10.1016/j.carbpol.2020.116060. [PMID: 32172875]
  • Jinping Wang, Xiaoyu Wang, Xiaohua Pan, Wei Pan, Ye Li, Xiangyu Liang, Xiaobo Sun. Dual-emission carbon dots achieved by luminescence center modulation within one-pot synthesis for a fluorescent ratiometric probe of pH, Hg2+, and glutathione. Mikrochimica acta. 2020 05; 187(6):330. doi: 10.1007/s00604-020-04311-w. [PMID: 32409915]
  • Weiyu Zhao, Han Cheng, Yu Zhu. A compound reflects the level of homocysteine based on Rhodamine B and its ability to respond to homocysteine in the plasma of diabetic patients. Journal of clinical laboratory analysis. 2020 May; 34(5):e23202. doi: 10.1002/jcla.23202. [PMID: 31995653]
  • Thasleem Moolakkadath, Mohd Aqil, Abdul Ahad, Syed Sarim Imam, Arshiya Praveen, Yasmin Sultana, Mohd Mujeeb. Preparation and optimization of fisetin loaded glycerol based soft nanovesicles by Box-Behnken design. International journal of pharmaceutics. 2020 Mar; 578(?):119125. doi: 10.1016/j.ijpharm.2020.119125. [PMID: 32036010]
  • Varadharajan Bhooma, Krishnan Nagasathiya, Mariappanadar Vairamani, Madasamy Parani. Identification of synthetic dyes magenta III (new fuchsin) and rhodamine B as common adulterants in commercial saffron. Food chemistry. 2020 Mar; 309(?):125793. doi: 10.1016/j.foodchem.2019.125793. [PMID: 31699557]
  • Di Zhang, Zhiwei Ma, Yanliang Wang, Haiyan Yin, Man Li, Yun Wang, Hongqi Wang, Bin Jia, Jihong Liu. Dual-binding benzene and rhodamine B conjugate derivatives as fluorescent chemodosimeter for hypochlorite in living cell imaging. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2020 Mar; 229(?):117908. doi: 10.1016/j.saa.2019.117908. [PMID: 31841672]
  • Guohua Ding, Luyong Wu, Huajie Feng, Yanping Liu, Jianling Li, Hongzong Si, Xiaojun Yao, Mengxiong He, Wenying He. The specific binding of a new 1,2,3-triazole to three blood proteins and it's appended rhodamine complex for selective detection of Hg2. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2020 Mar; 228(?):117728. doi: 10.1016/j.saa.2019.117728. [PMID: 31748164]
  • Huimin Fan, Yongwen Ma, Jinquan Wan, Yan Wang. Removal of gentian violet and rhodamine B using banyan aerial roots after modification and mechanism studies of differential adsorption behaviors. Environmental science and pollution research international. 2020 Mar; 27(9):9152-9166. doi: 10.1007/s11356-019-07024-7. [PMID: 31916156]
  • Minoo Bagheri, Mohammad Yaser Masoomi. Sensitive Ratiometric Fluorescent Metal-Organic Framework Sensor for Calcium Signaling in Human Blood Ionic Concentration Media. ACS applied materials & interfaces. 2020 Jan; 12(4):4625-4631. doi: 10.1021/acsami.9b20489. [PMID: 31909960]
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  • Xiaolin Zhu, Guanlan Wu, Yi Xing, Chengzhi Wang, Xing Yuan, Baikun Li. Evaluation of single and combined toxicity of bisphenol A and its analogues using a highly-sensitive micro-biosensor. Journal of hazardous materials. 2020 01; 381(?):120908. doi: 10.1016/j.jhazmat.2019.120908. [PMID: 31352154]
  • Franziska Doll, Philipp Keckeis, Patricia Scheel, Helmut Cölfen. Visualizing Cholesterol Uptake by Self-Assembling Rhodamine B-Labeled Polymer Inside Living Cells via FLIM-FRET Microscopy. Macromolecular bioscience. 2020 01; 20(1):e1900081. doi: 10.1002/mabi.201900081. [PMID: 31222918]
  • Ya Gao, Mengmeng Hou, Ruihao Yang, Lei Zhang, Zhigang Xu, Yuejun Kang, Peng Xue. Transdermal delivery of therapeutics through dissolvable gelatin/sucrose films coated on PEGDA microneedle arrays with improved skin permeability. Journal of materials chemistry. B. 2019 12; 7(47):7515-7524. doi: 10.1039/c9tb01994d. [PMID: 31714572]
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  • Guoxin Tan, Jinyu Li, Yiming Song, Yibin Yu, Dandan Liu, Weisan Pan. Phenylboronic acid-tethered chondroitin sulfate-based mucoadhesive nanostructured lipid carriers for the treatment of dry eye syndrome. Acta biomaterialia. 2019 11; 99(?):350-362. doi: 10.1016/j.actbio.2019.08.035. [PMID: 31449929]
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  • Marwan Y Rezk, Marwa Zeitoun, A N El-Shazly, Mostafa M Omar, Nageh K Allam. Robust photoactive nanoadsorbents with antibacterial activity for the removal of dyes. Journal of hazardous materials. 2019 10; 378(?):120679. doi: 10.1016/j.jhazmat.2019.05.072. [PMID: 31200223]
  • Thivaharan Varadavenkatesan, Elizaveta Lyubchik, Shraddha Pai, Arivalagan Pugazhendhi, Ramesh Vinayagam, Raja Selvaraj. Photocatalytic degradation of Rhodamine B by zinc oxide nanoparticles synthesized using the leaf extract of Cyanometra ramiflora. Journal of photochemistry and photobiology. B, Biology. 2019 Oct; 199(?):111621. doi: 10.1016/j.jphotobiol.2019.111621. [PMID: 31610434]
  • Muhammad Jan Akhunzada, Luca Sagresti, Andrea Catte, Nicholus Bhattacharjee, Tommaso D'Agostino, Giuseppe Brancato. Temperature Dependence of the Structure and Dynamics of a Dye-Labeled Lipid in a Planar Phospholipid Bilayer: A Computational Study. The Journal of membrane biology. 2019 10; 252(4-5):227-240. doi: 10.1007/s00232-019-00081-6. [PMID: 31332471]
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