Hexafluoroisopropanol (BioDeep_00000054192)

   

human metabolite Endogenous blood metabolite


代谢物信息卡片


2,2,2-Trifluoro-1-(trifluoromethyl)ethanol

化学式: C3H2F6O (168.0009834)
中文名称: 六氟异丙醇(HFIP)
谱图信息: 最多检出来源 Homo sapiens(blood) 8.16%

分子结构信息

SMILES: C(C(F)(F)F)(C(F)(F)F)O
InChI: InChI=1S/C3H2F6O/c4-2(5,6)1(10)3(7,8)9/h1,10H

描述信息

Hexafluoroisopropanol is a metabolite of sevoflurane. Sevoflurane (1,1,1,3,3,3-hexafluoro-2-propane), also called fluoromethyl hexafluoroisopropyl ether, is a sweet-smelling, nonflammable, highly fluorinated methyl isopropyl ether used for induction and maintenance of general anesthesia. Together with desflurane, it is replacing isoflurane and halothane in modern anesthesiology. It is often administered in a mixture of nitrous oxide and oxygen. After desflurane, it is the volatile anesthetic with the fastest onset and offset. (Wikipedia)

同义名列表

13 个代谢物同义名

2,2,2-Trifluoro-1-(trifluoromethyl)ethanol; 1,1,1,3,3,3-Hexafluoroisopropyl alcohol; 1,1,1,3,3,3-Hexafluoro-2-hydroxypropane; 1,1,1,3,3,3-hexafluoro-2-propanol; 1,1,1,3,3,3-Hexafluoroisopropanol; 1,1,1,3,3,3-hexafluoropropan-2-ol; Bis(trifluoromethyl)methanol; Hexafluoroisopropyl alcohol; 2H-Hexafluoroisopropanol; Hexafluoro-2-propanol; Hexafluoroisopropanol; Hexafluoropropanol; HFIP



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Anqi Huang, Wenwen Deng, Dandan Wu, Shuwen Wu, Yuxiu Xiao. Hexafluoroisopropanol-salt aqueous two-phase system for extraction and purification of chlorogenic acid from ramie leaves. Journal of chromatography. A. 2019 Jul; 1597(?):196-201. doi: 10.1016/j.chroma.2019.04.046. [PMID: 31054834]
  • Amir Koolivand, Mohammadmehdi Azizi, Ariel O'Brien, Morteza G Khaledi. Coacervation of Lipid Bilayer in Natural Cell Membranes for Extraction, Fractionation, and Enrichment of Proteins in Proteomics Studies. Journal of proteome research. 2019 04; 18(4):1595-1606. doi: 10.1021/acs.jproteome.8b00857. [PMID: 30810315]
  • Yu Zong, Jia Chen, Jinxuan Hou, Wenwen Deng, Xiaoyan Liao, Yuxiu Xiao. Hexafluoroisopropanol-alkyl carboxylic acid high-density supramolecular solvent based dispersive liquid-liquid microextraction of steroid sex hormones in human urine. Journal of chromatography. A. 2018 Dec; 1580(?):12-21. doi: 10.1016/j.chroma.2018.10.041. [PMID: 30391035]
  • Sebastien Perbet, Daniel Bourdeaux, Alexandre Lenoire, Claire Biboulet, Bruno Pereira, Malha Sadoune, Benoit Plaud, Jean-Marie Launay, Jean-Etienne Bazin, Valerie Sautou, Alexandre Mebazaa, Pascal Houze, Jean-Michel Constantin, Matthieu Legrand. Sevoflurane for procedural sedation in critically ill patients: A pharmacokinetic comparative study between burn and non-burn patients. Anaesthesia, critical care & pain medicine. 2018 12; 37(6):551-556. doi: 10.1016/j.accpm.2018.02.001. [PMID: 29455032]
  • Silvia Grande, Pieter Cools, Mahtab Asadian, Joachim Van Guyse, Iuliia Onyshchenko, Heidi Declercq, Rino Morent, Richard Hoogenboom, Nathalie De Geyter. Fabrication of PEOT/PBT Nanofibers by Atmospheric Pressure Plasma Jet Treatment of Electrospinning Solutions for Tissue Engineering. Macromolecular bioscience. 2018 12; 18(12):e1800309. doi: 10.1002/mabi.201800309. [PMID: 30353664]
  • Łukasz Nuckowski, Anna Kaczmarkiewicz, Sylwia Studzińska. Development of SPE method for the extraction of phosphorothioate oligonucleotides from serum samples. Bioanalysis. 2018 Oct; 10(20):1667-1677. doi: 10.4155/bio-2018-0166. [PMID: 30354278]
  • Yoon-Hui Sung, David Eliezer. Structure and dynamics of the extended-helix state of alpha-synuclein: Intrinsic lability of the linker region. Protein science : a publication of the Protein Society. 2018 07; 27(7):1314-1324. doi: 10.1002/pro.3426. [PMID: 29663556]
  • Sylwia Studzińska, Rafał Rola, Bogusław Buszewski. The impact of ion-pairing reagents on the selectivity and sensitivity in the analysis of modified oligonucleotides in serum samples by liquid chromatography coupled with tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis. 2017 May; 138(?):146-152. doi: 10.1016/j.jpba.2017.02.014. [PMID: 28208106]
  • Rūta Veigure, Rudolf Aro, Tuuli Metsvaht, Joseph F Standing, Irja Lutsar, Koit Herodes, Karin Kipper. A highly sensitive method for the simultaneous UHPLC-MS/MS analysis of clonidine, morphine, midazolam and their metabolites in blood plasma using HFIP as the eluent additive. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 May; 1052(?):150-157. doi: 10.1016/j.jchromb.2017.03.007. [PMID: 28388512]
  • V S Chernonosova, R I Kvon, E V Kiseleva, A O Stepanova, P P Laktionov. [Investigation of the surface layer of 3D-matrices for tissue engineering]. Biomeditsinskaia khimiia. 2017 Jan; 63(1):32-38. doi: 10.18097/pbmc2017630132. [PMID: 28251949]
  • M Urner, M Schläpfer, I K Herrmann, M Hasler, R R Schimmer, C Booy, B Roth Z'graggen, H Rehrauer, F Aigner, R D Minshall, W J Stark, B Beck-Schimmer. Insight into the beneficial immunomodulatory mechanism of the sevoflurane metabolite hexafluoro-2-propanol in a rat model of endotoxaemia. Clinical and experimental immunology. 2015 Sep; 181(3):468-79. doi: 10.1111/cei.12648. [PMID: 25925908]
  • Yin-Kai Chao, Cheng-Hung Lee, Kuo-Sheng Liu, Yi-Chuan Wang, Chih-Wei Wang, Shih-Jung Liu. Sustained release of bactericidal concentrations of penicillin in the pleural space via an antibiotic-eluting pigtail catheter coated with electrospun nanofibers: results from in vivo and in vitro studies. International journal of nanomedicine. 2015; 10(?):3329-36. doi: 10.2147/ijn.s82228. [PMID: 26005344]
  • Maria Luisa Scapellato, Mariella Carrieri, Isabella Maccà, Fabiola Salamon, Andrea Trevisan, Maurizio Manno, Giovanni Battista Bartolucci. Biomonitoring occupational sevoflurane exposure at low levels by urinary sevoflurane and hexafluoroisopropanol. Toxicology letters. 2014 Dec; 231(2):154-60. doi: 10.1016/j.toxlet.2014.10.018. [PMID: 25455444]
  • Debasish Sen, Dipak K Mandal. A comparative study of unfolding of Erythrina cristagalli Lectin in chemical denaturant and Fluoroalcohols. Protein and peptide letters. 2014; 21(1):80-9. doi: 10.2174/09298665113209990088. [PMID: 23964743]
  • Katherine E Gregory, Susan S Bird, Vera S Gross, Vasant R Marur, Alexander V Lazarev, W Allan Walker, Bruce S Kristal. Method development for fecal lipidomics profiling. Analytical chemistry. 2013 Jan; 85(2):1114-23. doi: 10.1021/ac303011k. [PMID: 23210743]
  • Kaisheng Jiao, Aftab Rashid, Sujit K Basu, Shuhao Zhu, Bob D Brown, Roberto Guerciolini, Douglas M Fambrough. Quantitative analysis of dicer substrate oligonucleotides in mouse liver by ultra-high-performance liquid chromatography-electrospray ionization tandem mass spectrometry. Assay and drug development technologies. 2012 Jun; 10(3):278-88. doi: 10.1089/adt.2011.0435. [PMID: 22192311]
  • Janka Kubincová, Alexandra Szabóová, Peter Podolec, Jaroslav Blaško, Ladislav Soják, Renáta Górová, Gabriela Addová, Ivan Ostrovský, Jozef Višňovský, Anton Amann, Paweł Mochalski, Judith Höfer, Arnulf Benzer, Darina Behúlová, Róbert Kubinec. Determination of sevoflurane and its metabolite hexafluoroisopropanol by direct injection of human plasma into gas chromatography-tandem mass spectrometry. Journal of chromatography. A. 2012 Jan; 1219(?):173-6. doi: 10.1016/j.chroma.2011.10.054. [PMID: 22137778]
  • Maria I Lioudyno, Matteo Broccio, Yuri Sokolov, Suhail Rasool, Jessica Wu, Michael T Alkire, Virginia Liu, J Ashot Kozak, Philip R Dennison, Charles G Glabe, Mathias Lösche, James E Hall. Effect of synthetic aβ peptide oligomers and fluorinated solvents on Kv1.3 channel properties and membrane conductance. PloS one. 2012; 7(4):e35090. doi: 10.1371/journal.pone.0035090. [PMID: 22563377]
  • Shilpa Mishra Shukla, Shiv K Sharma. Sinomenine inhibits microglial activation by Aβ and confers neuroprotection. Journal of neuroinflammation. 2011 Sep; 8(?):117. doi: 10.1186/1742-2094-8-117. [PMID: 21917137]
  • Peter Hoogerhout, Willem Kamphuis, Humphrey F Brugghe, Jacqueline A Sluijs, Hans A M Timmermans, Janny Westdijk, Gijsbert Zomer, Claire J P Boog, Elly M Hol, Germie P J M van den Dobbelsteen. A cyclic undecamer peptide mimics a turn in folded Alzheimer amyloid β and elicits antibodies against oligomeric and fibrillar amyloid and plaques. PloS one. 2011 Apr; 6(4):e19110. doi: 10.1371/journal.pone.0019110. [PMID: 21526148]
  • Matthew C Phipps, William C Clem, Shane A Catledge, Yuanyuan Xu, Kristin M Hennessy, Vinoy Thomas, Michael J Jablonsky, Shafiul Chowdhury, Andrei V Stanishevsky, Yogesh K Vohra, Susan L Bellis. Mesenchymal stem cell responses to bone-mimetic electrospun matrices composed of polycaprolactone, collagen I and nanoparticulate hydroxyapatite. PloS one. 2011 Feb; 6(2):e16813. doi: 10.1371/journal.pone.0016813. [PMID: 21346817]
  • Phillip M Pifer, Elizabeth A Yates, Justin Legleiter. Point mutations in Aβ result in the formation of distinct polymorphic aggregates in the presence of lipid bilayers. PloS one. 2011 Jan; 6(1):e16248. doi: 10.1371/journal.pone.0016248. [PMID: 21267410]
  • Yuhai Zhao, Frederic Calon, Carl Julien, Jeremy W Winkler, Nicos A Petasis, Walter J Lukiw, Nicolas G Bazan. Docosahexaenoic acid-derived neuroprotectin D1 induces neuronal survival via secretase- and PPARγ-mediated mechanisms in Alzheimer's disease models. PloS one. 2011 Jan; 6(1):e15816. doi: 10.1371/journal.pone.0015816. [PMID: 21246057]
  • Sadie C Slater, Vince Beachley, Thomas Hayes, Daming Zhang, Gavin I Welsh, Moin A Saleem, Peter W Mathieson, Xuejun Wen, Bo Su, Simon C Satchell. An in vitro model of the glomerular capillary wall using electrospun collagen nanofibres in a bioartificial composite basement membrane. PloS one. 2011; 6(6):e20802. doi: 10.1371/journal.pone.0020802. [PMID: 21731625]
  • Mobeen Raja. Monitoring the effects of strong cosolvent hexafluoroisopropanol in investigation of the tetrameric structure and stability of K(+)-channel KcsA. Archives of biochemistry and biophysics. 2010 Jun; 498(1):1-6. doi: 10.1016/j.abb.2010.03.014. [PMID: 20347712]
  • Brian O'Nuallain, Angela D Williams, Helen P McWilliams-Koeppen, Luis Acero, Alfred Weber, Hartmut Ehrlich, Hans P Schwarz, Alan Solomon. Anti-amyloidogenic activity of IgGs contained in normal plasma. Journal of clinical immunology. 2010 May; 30 Suppl 1(?):S37-42. doi: 10.1007/s10875-010-9413-6. [PMID: 20405179]
  • Frans J Walther, Alan J Waring, Jose M Hernandez-Juviel, Larry M Gordon, Zhengdong Wang, Chun-Ling Jung, Piotr Ruchala, Andrew P Clark, Wesley M Smith, Shantanu Sharma, Robert H Notter. Critical structural and functional roles for the N-terminal insertion sequence in surfactant protein B analogs. PloS one. 2010 Jan; 5(1):e8672. doi: 10.1371/journal.pone.0008672. [PMID: 20084172]
  • Daniel Bourdeaux, Valérie Sautou-Miranda, Agnès Montagner, Sébastien Perbet, Jean Michel Constantin, Jean-Etienne Bazin, Jean Chopineau. Simple assay of plasma sevoflurane and its metabolite hexafluoroisopropanol by headspace GC-MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2010 Jan; 878(1):45-50. doi: 10.1016/j.jchromb.2009.11.018. [PMID: 19948429]
  • Ricardo Capone, Felipe Garcia Quiroz, Panchika Prangkio, Inderjeet Saluja, Anna M Sauer, Mahealani R Bautista, Raymond S Turner, Jerry Yang, Michael Mayer. Amyloid-beta-induced ion flux in artificial lipid bilayers and neuronal cells: resolving a controversy. Neurotoxicity research. 2009 Jul; 16(1):1-13. doi: 10.1007/s12640-009-9033-1. [PMID: 19526294]
  • Thuzar M Shin, J Mario Isas, Chia-Ling Hsieh, Rakez Kayed, Charles G Glabe, Ralf Langen, Jeannie Chen. Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin. Molecular neurodegeneration. 2008 Oct; 3(?):16. doi: 10.1186/1750-1326-3-16. [PMID: 18939994]
  • Steffen Steinert, Esther Lee, Guillaume Tresset, Dawei Zhang, Ralf Hortsch, Richard Wetzel, Sarita Hebbar, Jeyapriya Raja Sundram, Sashi Kesavapany, Elke Boschke, Rachel Kraut. A fluorescent glycolipid-binding peptide probe traces cholesterol dependent microdomain-derived trafficking pathways. PloS one. 2008 Aug; 3(8):e2933. doi: 10.1371/journal.pone.0002933. [PMID: 18716682]
  • C Barbas, M Vallejo, A García, D Barlow, M Hanna-Brown. Capillary electrophoresis as a metabolomic tool in antioxidant therapy studies. Journal of pharmaceutical and biomedical analysis. 2008 Jun; 47(2):388-98. doi: 10.1016/j.jpba.2008.01.028. [PMID: 18314289]
  • D J Bennett, E L Carswell, A J Cooke, A S Edwards, O Nimz. Design, structure activity relationships and X-Ray co-crystallography of non-steroidal LXR agonists. Current medicinal chemistry. 2008; 15(2):195-209. doi: 10.2174/092986708783330584. [PMID: 18220775]
  • Farah Naseem, Rizwan Hasan Khan. Pea lectin in alkaline conditions: formation of molten globule-like intermediate and its structural and thermal studies under the influence of hexafluoroisopropanol. Protein and peptide letters. 2008; 15(6):606-11. doi: 10.2174/092986608784966868. [PMID: 18680456]
  • Haruhiko Yagi, Donald M Jerina. Fluorinated alcohol mediated displacement of the C10 acetoxy group of benzo[a]pyrene-7,8,9,10-tetrahydrotetraol tetraacetates: a new route to diol epoxide-deoxyguanosine adducts. The Journal of organic chemistry. 2007 Dec; 72(26):9983-90. doi: 10.1021/jo701705c. [PMID: 18047370]
  • Elena Karnaukhova, Yakir Ophir, Loc Trinh, Nimish Dalal, Peter J Punt, Basil Golding, Joseph Shiloach. Expression of human alpha1-proteinase inhibitor in Aspergillus niger. Microbial cell factories. 2007 Oct; 6(?):34. doi: 10.1186/1475-2859-6-34. [PMID: 17967194]
  • Haruhiko Yagi, Donald M Jerina. Fluorinated alcohol mediated control over cis vs trans opening of benzo[a]pyrene-7,8-diol 9,10-epoxides at C-10 by the exocyclic amino groups of O6-allyl protected deoxyguanosine and of deoxyadenosine. The Journal of organic chemistry. 2007 Aug; 72(16):6037-45. doi: 10.1021/jo070303c. [PMID: 17608435]
  • D E Otzen, P Sehgal, L W Nesgaard. Alternative membrane protein conformations in alcohols. Biochemistry. 2007 Apr; 46(14):4348-59. doi: 10.1021/bi700091r. [PMID: 17371052]
  • Su-Yong Eun, Hae-Kyung Jang, Seong-Kyu Han, Pan-Dong Ryu, Byeong-Jae Lee, Kyou-Hoon Han, Soon-Jong Kim. A helix-induced oligomeric transition of gaegurin 4, an antimicrobial peptide isolated from a Korean frog. Molecules and cells. 2006 Apr; 21(2):229-36. doi: ". [PMID: 16682818]
  • Ko Eun Park, Hyun Ki Kang, Seung Jin Lee, Byung-Moo Min, Won Ho Park. Biomimetic nanofibrous scaffolds: preparation and characterization of PGA/chitin blend nanofibers. Biomacromolecules. 2006 Feb; 7(2):635-43. doi: 10.1021/bm0509265. [PMID: 16471941]
  • Jun Zhou, Maria I Fonseca, Rakez Kayed, Irma Hernandez, Scott D Webster, Ozkan Yazan, David H Cribbs, Charles G Glabe, Andrea J Tenner. Novel Abeta peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease. Journal of neuroinflammation. 2005 Dec; 2(?):28. doi: 10.1186/1742-2094-2-28. [PMID: 16332263]
  • Yogesh Kumar, Salman Muzammil, Saad Tayyab. Influence of fluoro, chloro and alkyl alcohols on the folding pathway of human serum albumin. Journal of biochemistry. 2005 Oct; 138(4):335-41. doi: 10.1093/jb/mvi131. [PMID: 16272127]
  • Soghra Khatun Haq, Rizwan Hasan Khan. Effect of detergents and hexafluoroisopropanol on the conformation of a non-helical and a helical plant protease inhibitor. International journal of biological macromolecules. 2005 Jul; 36(1-2):47-53. doi: 10.1016/j.ijbiomac.2005.03.008. [PMID: 16022894]
  • Farah Naseem, Rizwan Hasan Khan. Characterization of a common intermediate of pea lectin in the folding pathway induced by TFE and HFIP. Biochimica et biophysica acta. 2005 May; 1723(1-3):192-200. doi: 10.1016/j.bbagen.2005.02.009. [PMID: 15840464]
  • Antonio Accorsi, Barbara Morrone, Maurizio Benzo, Carlo Gandini, Giovanni Battista Raffi, Francesco Saverio Violante. Simultaneous determination of unmodified sevoflurane and of its metabolite hexafluoroisopropanol in urine by headspace sorptive extraction-thermal desorption-capillary gas chromatography-mass spectrometry. Journal of chromatography. A. 2005 Apr; 1071(1-2):131-4. doi: 10.1016/j.chroma.2004.09.039. [PMID: 15865184]
  • Gabriele Leng, Wolfgang Gries. Simultaneous determination of pyrethroid and pyrethrin metabolites in human urine by gas chromatography-high resolution mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2005 Jan; 814(2):285-94. doi: 10.1016/j.jchromb.2004.10.044. [PMID: 15639450]
  • Sue M Ennaceur, John M Sanderson. Micellar aggregates formed following the addition of hexafluoroisopropanol to phospholipid membranes. Langmuir : the ACS journal of surfaces and colloids. 2005 Jan; 21(2):552-61. doi: 10.1021/la048109y. [PMID: 15641823]
  • Valerie Booth, Alan J Waring, Frans J Walther, Kevin M W Keough. NMR structures of the C-terminal segment of surfactant protein B in detergent micelles and hexafluoro-2-propanol. Biochemistry. 2004 Dec; 43(48):15187-94. doi: 10.1021/bi0481895. [PMID: 15568810]
  • Farah Naseem, Rizwan Hasan Khan. Fluoroalcohol-induced stabilization of the alpha-helical intermediates of lentil lectin: implication for non-hierarchical lectin folding. Archives of biochemistry and biophysics. 2004 Nov; 431(2):215-23. doi: 10.1016/j.abb.2004.07.029. [PMID: 15488470]
  • Yogesh Kumar, Saad Tayyab, Salman Muzammil. Molten-globule like partially folded states of human serum albumin induced by fluoro and alkyl alcohols at low pH. Archives of biochemistry and biophysics. 2004 Jun; 426(1):3-10. doi: 10.1016/j.abb.2004.03.025. [PMID: 15130777]
  • John M Sanderson, Andrew D Ward. Analysis of liposomal membrane composition using Raman tweezers. Chemical communications (Cambridge, England). 2004 May; ?(9):1120-1. doi: 10.1039/b316757g. [PMID: 15116214]
  • E A Mal'tseva, G Bretsesinskiĭ. [Interaction of amyloid beta-(1-40) peptide with model membranes]. Biofizika. 2004 Jan; 49(1):38-46. doi: ". [PMID: 15029719]
  • L Elflein, E Berger-Preiss, A Preiss, M Elend, K Levsen, G Wünsch. Human biomonitoring of pyrethrum and pyrethroid insecticides used indoors: determination of the metabolites E-cis/trans-chrysanthemumdicarboxylic acid in human urine by gas chromatography-mass spectrometry with negative chemical ionization. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2003 Oct; 795(2):195-207. doi: 10.1016/s1570-0232(03)00566-x. [PMID: 14522024]
  • F Barbic, M Bagnati, M Basile, V Zanoli, L Carettoni, C Cassani, P Porta, A Fortina, C Mantovani, G Bellomo. [Urinary hexafluoroisopropanol in the assessment of occupational exposure to sevoflurane: methodologic features and critical points]. Giornale italiano di medicina del lavoro ed ergonomia. 2003 Jul; 25 Suppl(3):95-7. doi: NULL. [PMID: 14979101]
  • Larissa A Munishkina, Cassandra Phelan, Vladimir N Uversky, Anthony L Fink. Conformational behavior and aggregation of alpha-synuclein in organic solvents: modeling the effects of membranes. Biochemistry. 2003 Mar; 42(9):2720-30. doi: 10.1021/bi027166s. [PMID: 12614167]
  • M Buratti, C Valla, D Xaiz, G Brambilla, A Colombi. Determination of hexafluoroisopropanol, a sevoflurane urinary metabolite, by 9-fluorenylmethyl chloroformate derivatization. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2002 Sep; 776(2):237-43. doi: 10.1016/s1570-0232(02)00310-0. [PMID: 12138006]
  • Hiroshi Sakamoto, Takahisa Mayumi, Yuji Morimoto, Osamu Kemmotsu, Hiroshi Wakisaka, Takemi Ohno. Sevoflurane metabolite production in a small cohort of coronary artery bypass graft surgery patients. Journal of cardiothoracic and vascular anesthesia. 2002 Aug; 16(4):463-7. doi: 10.1053/jcan.2002.125141. [PMID: 12154427]
  • Sonja Hess, Frederick J Cassels, Lewis K Pannell. Identification and characterization of hydrophobic Escherichia coli virulence proteins by liquid chromatography-electrospray ionization mass spectrometry. Analytical biochemistry. 2002 Mar; 302(1):123-30. doi: 10.1006/abio.2001.5534. [PMID: 11846385]
  • Larry M Gordon, Patrick W Mobley, Rosemarie Pilpa, Mark A Sherman, Alan J Waring. Conformational mapping of the N-terminal peptide of HIV-1 gp41 in membrane environments using (13)C-enhanced Fourier transform infrared spectroscopy. Biochimica et biophysica acta. 2002 Feb; 1559(2):96-120. doi: 10.1016/s0005-2736(01)00443-6. [PMID: 11853678]
  • W Huang, D E Moody, D M Andrenyak, E K Smith, R L Foltz, M A Huestis, J F Newton. Simultaneous determination of delta9-tetrahydrocannabinol and 11-nor-9-carboxy-delta9-tetrahydrocannabinol in human plasma by solid-phase extraction and gas chromatography-negative ion chemical ionization-mass spectrometry. Journal of analytical toxicology. 2001 Oct; 25(7):531-7. doi: 10.1093/jat/25.7.531. [PMID: 11599596]
  • D V Greathouse, R L Goforth, T Crawford, P C Van Der Wel, J A Killian. Optimized aminolysis conditions for cleavage of N-protected hydrophobic peptides from solid-phase resins. The journal of peptide research : official journal of the American Peptide Society. 2001 Jun; 57(6):519-27. doi: 10.1034/j.1399-3011.2001.00849.x. [PMID: 11437955]
  • M Imbriani, P Zadra, S Negri, A Alessio, L Maestri, S Ghittori. [Biological monitoring of occupational exposure to sevoflurane]. La Medicina del lavoro. 2001 May; 92(3):173-80. doi: . [PMID: 11515150]
  • S Kimura, A Naito, S Tuzi, H Saitô. A (13)C NMR study on [3-(13)C]-, [1-(13)C]Ala-, or [1-(13)C]Val-labeled transmembrane peptides of bacteriorhodopsin in lipid bilayers: insertion, rigid-body motions, and local conformational fluctuations at ambient temperature. Biopolymers. 2001 Jan; 58(1):78-88. doi: 10.1002/1097-0282(200101)58:1<78::aid-bip80>3.0.co;2-c. [PMID: 11072231]
  • M Thunecke, A Lobbia, U Kosciessa, T Dyrks, A E Oakley, J Turner, W Saenger, Y Georgalis. Aggregation of A beta Alzheimer's disease-related peptide studied by dynamic light scattering. The journal of peptide research : official journal of the American Peptide Society. 1998 Dec; 52(6):509-17. doi: 10.1111/j.1399-3011.1998.tb01255.x. [PMID: 9924995]
  • S M Davies, S M Kelly, N C Price, J P Bradshaw. Structural plasticity of the feline leukaemia virus fusion peptide: a circular dichroism study. FEBS letters. 1998 Apr; 425(3):415-8. doi: 10.1016/s0014-5793(98)00274-9. [PMID: 9563505]
  • W Chan, J Fornwald, M Brawner, R Wetzel. Native complex formation between apolipoprotein E isoforms and the Alzheimer's disease peptide A beta. Biochemistry. 1996 Jun; 35(22):7123-30. doi: 10.1021/bi952852v. [PMID: 8679539]
  • E D Kharasch. Biotransformation of sevoflurane. Anesthesia and analgesia. 1995 Dec; 81(6 Suppl):S27-38. doi: 10.1097/00000539-199512001-00005. [PMID: 7486145]
  • M D Green, D J Clarke, E M Oturu, P B Styczynski, M R Jackson, B Burchell, T R Tephly. Cloning and expression of a rat liver phenobarbital-inducible UDP-glucuronosyltransferase (2B12) with specificity for monoterpenoid alcohols. Archives of biochemistry and biophysics. 1995 Oct; 322(2):460-8. doi: 10.1006/abbi.1995.1489. [PMID: 7574722]
  • T P Malan, T Sameshima, H Mata, E J Frink. Relationship of inspired anesthetic concentration to plasma concentration and urinary excretion of sevoflurane metabolites in rats. Anesthesia and analgesia. 1995 Sep; 81(3):576-80. doi: 10.1097/00000539-199509000-00027. [PMID: 7653826]
  • E D Kharasch, M D Karol, C Lanni, R Sawchuk. Clinical sevoflurane metabolism and disposition. I. Sevoflurane and metabolite pharmacokinetics. Anesthesiology. 1995 Jun; 82(6):1369-78. doi: 10.1097/00000542-199506000-00008. [PMID: 7793651]
  • E D Kharasch, A S Armstrong, K Gunn, A Artru, K Cox, M D Karol. Clinical sevoflurane metabolism and disposition. II. The role of cytochrome P450 2E1 in fluoride and hexafluoroisopropanol formation. Anesthesiology. 1995 Jun; 82(6):1379-88. doi: 10.1097/00000542-199506000-00009. [PMID: 7793652]
  • S E Morgan, E J Frink, A J Gandolfi. A simplified gas chromatographic method for quantifying the sevoflurane metabolite hexafluoroisopropanol. Anesthesiology. 1994 Jan; 80(1):201-5. doi: 10.1097/00000542-199401000-00027. [PMID: 8291710]
  • R E Aderjan, G Schmitt, M Wu, C Meyer. Determination of cocaine and benzoylecgonine by derivatization with iodomethane-D3 or PFPA/HFIP in human blood and urine using GC/MS (EI or PCI mode). Journal of analytical toxicology. 1993 Jan; 17(1):51-5. doi: 10.1093/jat/17.1.51. [PMID: 8429629]