9-Methylxanthine (BioDeep_00000053809)

Main id: BioDeep_00000014444

 

human metabolite


代谢物信息卡片


9-methyl-2,3,6,9-tetrahydro-1H-purine-2,6-dione

化学式: C6H6N4O2 (166.0490736)
中文名称: 9-甲基黄嘌呤
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN1C=NC2=C1NC(=O)NC2=O
InChI: InChI=1S/C6H6N4O2/c1-10-2-7-3-4(10)8-6(12)9-5(3)11/h2H,1H3,(H2,8,9,11,12)

描述信息

9-Methylxanthine is a diuretic agent that serves as a smooth muscle relexant and cardiac muscle and CNS stimulant. Clinically, it is employed as a bronchodilator. 9-Methylxanthine is found to be effective in treating apnea in preterm infants (PMID: 11686952). In another study, 9-Methylxanthine, as a chemical relatives of caffeine, is able to evoke contractures in mammalian heart. (PMID: 1226453)

同义名列表

4 个代谢物同义名

9-methyl-2,3,6,9-tetrahydro-1H-purine-2,6-dione; 1H-Purine-2,6-dione,3,9-dihydro-9-methyl-; 9-Methylxanthine; Methylxanthine



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Angela Sotelo, Daniela Soleri, Carmen Wacher, Argelia Sánchez-Chinchillas, Rosa Maria Argote. Chemical and nutritional composition of tejate, a traditional maize and cacao beverage from the Central Valleys of Oaxaca, Mexico. Plant foods for human nutrition (Dordrecht, Netherlands). 2012 Jun; 67(2):148-55. doi: 10.1007/s11130-012-0281-5. [PMID: 22407326]
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  • Dan Shan, Hong Mei Wu, Qi Yuan Yuan, Jun Li, Rong Le Zhou, Guan J Liu. Pentoxifylline for diabetic kidney disease. The Cochrane database of systematic reviews. 2012 Feb; ?(2):CD006800. doi: 10.1002/14651858.cd006800.pub2. [PMID: 22336824]
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  • Elzbieta Wyska. Pharmacokinetic interaction between verapamil and methylxanthine derivatives in mice. Drug metabolism letters. 2010 Jan; 4(1):15-24. doi: 10.2174/187231210790980390. [PMID: 20201780]
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  • Elayne C de Morais, Aliny Stefanuto, Graziela A Klein, Brunna C B Boaventura, Fernanda de Andrade, Elisabeth Wazlawik, Patrícia F Di Pietro, Marcelo Maraschin, Edson L da Silva. Consumption of yerba mate ( Ilex paraguariensis ) improves serum lipid parameters in healthy dyslipidemic subjects and provides an additional LDL-cholesterol reduction in individuals on statin therapy. Journal of agricultural and food chemistry. 2009 Sep; 57(18):8316-24. doi: 10.1021/jf901660g. [PMID: 19694438]
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