methylpiperazine (BioDeep_00000526204)
代谢物信息卡片
化学式: C5H12N2 (100.1)
中文名称: 1-甲基哌嗪
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN1CCNCC1
InChI: InChI=1S/C5H12N2/c1-7-4-2-6-3-5-7/h6H,2-5H2,1H3
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:166561
- PubChem: 53167
- Metlin: METLIN2008
- ChEMBL: CHEMBL1011
- CAS: 109-01-3
- RefMet: Methylpiperazine
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Anne-Charlotte Dubbelman, Alana Upthagrove, Jos H Beijnen, Serena Marchetti, Eugene Tan, Kimberly Krone, Suraj Anand, Jan H M Schellens. Disposition and metabolism of 14C-dovitinib (TKI258), an inhibitor of FGFR and VEGFR, after oral administration in patients with advanced solid tumors.
Cancer chemotherapy and pharmacology.
2012 Nov; 70(5):653-63. doi:
10.1007/s00280-012-1947-2
. [PMID: 23010851] - Hongyuan Yan, Fang Wang, Dandan Han, Gengliang Yang. Simultaneous determination of four plant hormones in bananas by molecularly imprinted solid-phase extraction coupled with high performance liquid chromatography.
The Analyst.
2012 Jun; 137(12):2884-90. doi:
10.1039/c2an35362h
. [PMID: 22553770] - Lang Shao, Yi Li, Jihong Yu, Ruren Xu. Divalent-metal-stabilized aluminophosphates exhibiting a new zeolite framework topology.
Inorganic chemistry.
2012 Jan; 51(1):225-9. doi:
10.1021/ic201515z
. [PMID: 22148757] - Mahreen Arooj, Sundarapandian Thangapandian, Shalini John, Swan Hwang, Jong Keun Park, Keun Woo Lee. 3D QSAR pharmacophore modeling, in silico screening, and density functional theory (DFT) approaches for identification of human chymase inhibitors.
International journal of molecular sciences.
2011; 12(12):9236-64. doi:
10.3390/ijms12129236
. [PMID: 22272131] - Changcheng Zhou, Suman Verma, Bruce Blumberg. The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism.
Nuclear receptor signaling.
2009; 7(?):e001. doi:
10.1621/nrs.07001
. [PMID: 19240808] - William J Watkins, Lee Chong, Aesop Cho, Ramona Hilgenkamp, Maria Ludwikow, Negar Garizi, Nadeem Iqbal, John Barnard, Rajeshwar Singh, Deidre Madsen, Karen Lolans, Olga Lomovskaya, Uma Oza, Padmapriya Kumaraswamy, Andrea Blecken, Shuang Bai, David J Loury, David C Griffith, Michael N Dudley. Quinazolinone fungal efflux pump inhibitors. Part 3: (N-methyl)piperazine variants and pharmacokinetic optimization.
Bioorganic & medicinal chemistry letters.
2007 May; 17(10):2802-6. doi:
10.1016/j.bmcl.2007.02.047
. [PMID: 17350259] - John C Reepmeyer, Jeffrey T Woodruff, D André d'Avignon. Structure elucidation of a novel analogue of sildenafil detected as an adulterant in an herbal dietary supplement.
Journal of pharmaceutical and biomedical analysis.
2007 Apr; 43(5):1615-21. doi:
10.1016/j.jpba.2006.11.037
. [PMID: 17207601] - Karin A Zemski Berry, Robert C Murphy. Analysis of cell membrane aminophospholipids as isotope-tagged derivatives.
Journal of lipid research.
2005 May; 46(5):1038-46. doi:
10.1194/jlr.m500014-jlr200
. [PMID: 15716579] - Takeshi Ohya, Masaru Niitsu. Identification of 4-methylspinaceamine--a Pictet-Spengler condensation reaction product of histamine with acetaldehyde--in human urine.
Life sciences.
2005 Jan; 76(11):1199-209. doi:
10.1016/j.lfs.2004.06.030
. [PMID: 15642591] - L Blok-Tip, B Zomer, F Bakker, K D Hartog, M Hamzink, J Ten Hove, M Vredenbregt, D De Kaste. Structure elucidation of sildenafil analogues in herbal products.
Food additives and contaminants.
2004 Aug; 21(8):737-48. doi:
10.1080/02652030412331272467
. [PMID: 15370823] - S V Okovityĭ. [New derivatives of triazino- and imidazoindole with hepatoprotective activity].
Biomeditsinskaia khimiia.
2004 May; 50(3):293-303. doi:
. [PMID: 15354541]
- D H Boschelli, F Ye, Y D Wang, M Dutia, S L Johnson, B Wu, K Miller, D W Powell, D Yaczko, M Young, M Tischler, K Arndt, C Discafani, C Etienne, J Gibbons, J Grod, J Lucas, J M Weber, F Boschelli. Optimization of 4-phenylamino-3-quinolinecarbonitriles as potent inhibitors of Src kinase activity.
Journal of medicinal chemistry.
2001 Nov; 44(23):3965-77. doi:
10.1021/jm0102250
. [PMID: 11689083] - U Breyer-Pfaff, H Wachsmuth. Tertiary N-glucuronides of clozapine and its metabolite desmethylclozapine in patient urine.
Drug metabolism and disposition: the biological fate of chemicals.
2001 Oct; 29(10):1343-8. doi:
NULL
. [PMID: 11560879] - H Welinder, L Hagmar, C Gustavsson. IgE antibodies against piperazine and N-methyl-piperazine in two asthmatic subjects.
International archives of allergy and applied immunology.
1986; 79(3):259-62. doi:
10.1159/000233983
. [PMID: 3949408]