CL(18:0/18:0/18:0/18:0) (BioDeep_00000051176)

   

human metabolite Endogenous


代谢物信息卡片


[(2R)-2,3-bis(octadecanoyloxy)propoxy][3-({[(2R)-2,3-bis(octadecanoyloxy)propoxy](hydroxy)phosphoryl}oxy)-2-hydroxypropoxy]phosphinic acid

化学式: C81H158O17P2 (1465.0973678)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COC(=O)CCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCC)O)OC(=O)CCCCCCCCCCCCCCCCC
InChI: InChI=1S/C81H158O17P2/c1-5-9-13-17-21-25-29-33-37-41-45-49-53-57-61-65-78(83)91-71-76(97-80(85)67-63-59-55-51-47-43-39-35-31-27-23-19-15-11-7-3)73-95-99(87,88)93-69-75(82)70-94-100(89,90)96-74-77(98-81(86)68-64-60-56-52-48-44-40-36-32-28-24-20-16-12-8-4)72-92-79(84)66-62-58-54-50-46-42-38-34-30-26-22-18-14-10-6-2/h75-77,82H,5-74H2,1-4H3,(H,87,88)(H,89,90)/t76-,77-/m1/s1

描述信息

CL(18:0/18:0/18:0/18:0) is a cardiolipin (CL). Cardiolipins are sometimes called double phospholipids because they have four fatty acid tails, instead of the usual two. They are glycerophospholipids in which the O1 and O3 oxygen atoms of the central glycerol moiety are each linked to one 1,3-diacylglyerol chain. Their general formula is OC(COP(O)(=O)OC[C@@H](CO[R1])O[R2])COP(O)(=O)OC[C@@H](CO[R3])O[R4], where R1-R4 are four fatty acyl chains. CL(18:0/18:0/18:0/18:0) contains four chains of octadecanoic acid at the C1, C2, C3 and C4 positions fatty acids. Cardiolipins are known to be present in all mammalian cells, especially cells with a high number of mitochondria. De novo synthesis of Cardiolipins begins with condensing phosphatidic acid (PA) with cytidine-5’-triphosphate (CTP) to form cytidine-diphosphate-1,2-diacyl-sn-glycerol (CDP-DG). Glycerol-3-phosphate is subsequently added to this newly formed CDP-DG molecule to form phosphatidylglycerol phosphate (PGP), which is immediately dephosphorylated to form PG. The final step is the process of condensing the PG molecule with another CDP-DG molecule to form a new cardiolipin, which is catalyzed by cardiolipin synthase. All new cardiolipins immediately undergo a series remodeling resulting in the common cardiolipin compositions. (PMID: 16442164). Cardiolipin synthase shows no selectivity for fatty acyl chains used in the de novo synthesis of cardiolipin (PMID: 16442164). Cardiolipins (bisphosphatidyl glycerol) are an important component of the inner mitochondrial membrane, where they constitute about 20\\% of the total lipid. While most lipids are made in the endoplasmic reticulum, cardiolipin is synthesized on the matrix side of the inner mitochondrial membrane and are important for mitochondrial respiratory capacity. They are highly abundant in metabolically active cells (heart, muscle) and play an important role in the blood clotting process. Tafazzin is an important enzyme in the remodeling of cardiolipins, and in contrast to cardiolipin synthase, it shows strong acyl specificity. This suggests that the specificity in cardiolipin composition is achieved through the remodeling steps. Mutation in the tafazzin gene disrupts the remodeling of cardiolipins and is the cause of Barth syndrome (BTHS), an X-linked human disease (PMID: 16973164). BTHS patients seem to lack acyl specificity. As a result, there are many potential cardiolipin species that can exist (PMID: 16226238).
Cl(18:0/18:0/18:0/18:0), also known as 1,12,2-tetra-dodecanoyl cardiolipin or tetrastearoylcardiolipin, is a member of the class of compounds known as cardiolipins. Cardiolipins are glycerophospholipids in which the O1 and O3 oxygen atoms of the central glycerol moiety are each linked to one 1,2-diacylglycerol chain. Their general formula is OC(COP(O)(=O)OC[C@@H](CO[R1])O[R2])COP(O)(=O)OC[C@@H](CO[R3])O[R4], where R1-R4 are four fatty acyl chains. Thus, cl(18:0/18:0/18:0/18:0) is considered to be a glycerophosphoglycerophosphoglycerol lipid molecule. Cl(18:0/18:0/18:0/18:0) is practically insoluble (in water) and a moderately acidic compound (based on its pKa). Cl(18:0/18:0/18:0/18:0) can be found in apple, cardamom, fig, and shiitake, which makes cl(18:0/18:0/18:0/18:0) a potential biomarker for the consumption of these food products. Cl(18:0/18:0/18:0/18:0) exists in all eukaryotes, ranging from yeast to humans. In humans, cl(18:0/18:0/18:0/18:0) is involved in the cardiolipin biosynthesis CL(18:0/18:0/18:0/18:0).

同义名列表

18 个代谢物同义名

[(2R)-2,3-bis(octadecanoyloxy)propoxy][3-({[(2R)-2,3-bis(octadecanoyloxy)propoxy](hydroxy)phosphoryl}oxy)-2-hydroxypropoxy]phosphinic acid; 1-[1,2-Dioctadecanoyl-rac-glycero-3-phospho],3-[1,2-dioctadecanoyl-rac-glycero-3-phospho]-glycerol; 1-[1,2-Distearoyl-rac-glycero-3-phospho],3-[1,2-distearoyl-rac-glycero-3-phospho]-glycerol; 1,12,2-Tetra-dodecanoyl cardiolipin; 1,12,2-Tetra-dodecanoylcardiolipin; 1,12,2-Tetrastearoyl cardiolipin; Cardiolipin(18:0/18:0/18:0/18:0); CL(1-[18:0/18:0],3-[18:0/18:0]); 1,12,2-Tetrastearoylcardiolipin; Tetra-dodecanoyl cardiolipin; Tetra-dodecanoylcardiolipin; Tetrastearoylcardiolipin; Diphosphatidylglycerols; CL(18:0/18:0/18:0/18:0); Cardiolipin(72:0); Cardiolipins; Cardiolipin; CL(72:0)



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

8 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(8)

PharmGKB(0)

17 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ke Xing, Sheng Qin, Guang-Kai Bian, Yue-Ji Zhang, Wen-Di Zhang, Chuan-Chao Dai, Chang-Hong Liu, Wen-Jun Li, Ji-Hong Jiang. Pseudonocardia nantongensis sp. nov., a novel endophytic actinomycete isolated from the coastal halophyte Tamarix chinensis Lour. Antonie van Leeuwenhoek. 2012 Nov; 102(4):659-67. doi: 10.1007/s10482-012-9764-5. [PMID: 22733061]
  • Jun Jie Zhang, Tian Yan Liu, Wen Feng Chen, En Tao Wang, Xin Hua Sui, Xiao Xia Zhang, Yán Li, Yàn Li, Wen Xin Chen. Mesorhizobium muleiense sp. nov., nodulating with Cicer arietinum L. International journal of systematic and evolutionary microbiology. 2012 Nov; 62(Pt 11):2737-2742. doi: 10.1099/ijs.0.038265-0. [PMID: 22228663]
  • Guang-Kai Bian, Zhao-Zhong Feng, Sheng Qin, Ke Xing, Zhe Wang, Cheng-Liang Cao, Chang-Hong Liu, Chuan-Chao Dai, Ji-Hong Jiang. Kineococcus endophytica sp. nov., a novel endophytic actinomycete isolated from a coastal halophyte in Jiangsu, China. Antonie van Leeuwenhoek. 2012 Nov; 102(4):621-8. doi: 10.1007/s10482-012-9757-4. [PMID: 22669199]
  • Diti Ronvelia, Jaclyn Greenwood, Julia Platt, Simin Hakim, Michael V Zaragoza. Intrafamilial variability for novel TAZ gene mutation: Barth syndrome with dilated cardiomyopathy and heart failure in an infant and left ventricular noncompaction in his great-uncle. Molecular genetics and metabolism. 2012 Nov; 107(3):428-32. doi: 10.1016/j.ymgme.2012.09.013. [PMID: 23031367]
  • Andrej Musatov, Neal C Robinson. Susceptibility of mitochondrial electron-transport complexes to oxidative damage. Focus on cytochrome c oxidase. Free radical research. 2012 Nov; 46(11):1313-26. doi: 10.3109/10715762.2012.717273. [PMID: 22856385]
  • Hironori Tsuchiya, Maki Mizogami, Kenji Shigemi. Increasing membrane interactions of local anaesthetics as hypothetic mechanism for their cardiotoxicity enhanced by myocardial ischaemia. Basic & clinical pharmacology & toxicology. 2012 Nov; 111(5):303-8. doi: 10.1111/j.1742-7843.2012.00909.x. [PMID: 22682403]
  • Jorge Sastre-Serra, Mercedes Nadal-Serrano, Daniel Gabriel Pons, Pilar Roca, Jordi Oliver. Mitochondrial dynamics is affected by 17β-estradiol in the MCF-7 breast cancer cell line. Effects on fusion and fission related genes. The international journal of biochemistry & cell biology. 2012 Nov; 44(11):1901-5. doi: 10.1016/j.biocel.2012.07.012. [PMID: 22824300]
  • Yan-Ru Cao, Yi Jiang, Rong-Xian Jin, Li Han, Wen-Xiang He, You-Long Li, Xue-Shi Huang, Quan-Hong Xue. Enteractinococcus coprophilus gen. nov., sp. nov., of the family Micrococcaceae, isolated from Panthera tigris amoyensis faeces, and transfer of Yaniella fodinae Dhanjal et al. 2011 to the genus Enteractinococcus as Enteractinococcus fodinae comb. nov. International journal of systematic and evolutionary microbiology. 2012 Nov; 62(Pt 11):2710-2716. doi: 10.1099/ijs.0.034249-0. [PMID: 22228667]
  • Anna Sotirova, Tatyana Avramova, Stoyanka Stoitsova, Irina Lazarkevich, Vera Lubenets, Elena Karpenko, Danka Galabova. The importance of rhamnolipid-biosurfactant-induced changes in bacterial membrane lipids of Bacillus subtilis for the antimicrobial activity of thiosulfonates. Current microbiology. 2012 Nov; 65(5):534-41. doi: 10.1007/s00284-012-0191-7. [PMID: 22810959]
  • Berta Vera, Silvia Santa Cruz, Gladis Magnarelli. Plasma cholinesterase and carboxylesterase activities and nuclear and mitochondrial lipid composition of human placenta associated with maternal exposure to pesticides. Reproductive toxicology (Elmsford, N.Y.). 2012 Nov; 34(3):402-7. doi: 10.1016/j.reprotox.2012.04.007. [PMID: 22580221]
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  • Susanne E Horvath, Lena Böttinger, F-Nora Vögtle, Nils Wiedemann, Chris Meisinger, Thomas Becker, Günther Daum. Processing and topology of the yeast mitochondrial phosphatidylserine decarboxylase 1. The Journal of biological chemistry. 2012 Oct; 287(44):36744-55. doi: 10.1074/jbc.m112.398107. [PMID: 22984266]
  • Atsushi Tsutsumi, Namsrai Javkhlantugs, Atsushi Kira, Masako Umeyama, Izuru Kawamura, Katsuyuki Nishimura, Kazuyoshi Ueda, Akira Naito. Structure and orientation of bovine lactoferrampin in the mimetic bacterial membrane as revealed by solid-state NMR and molecular dynamics simulation. Biophysical journal. 2012 Oct; 103(8):1735-43. doi: 10.1016/j.bpj.2012.09.010. [PMID: 23083717]
  • Teresa A Garrett, Ashley C O'Neill, Marquise L Hopson. Quantification of cardiolipin molecular species in Escherichia coli lipid extracts using liquid chromatography/electrospray ionization mass spectrometry. Rapid communications in mass spectrometry : RCM. 2012 Oct; 26(19):2267-74. doi: 10.1002/rcm.6350. [PMID: 22956318]
  • James J Asciolla, Thibaud T Renault, Jerry E Chipuk. Examining BCL-2 family function with large unilamellar vesicles. Journal of visualized experiments : JoVE. 2012 Oct; ?(68):. doi: 10.3791/4291. [PMID: 23070252]
  • André Lipski, Peter Kämpfer. Aquamicrobium ahrensii sp. nov. and Aquamicrobium segne sp. nov., isolated from experimental biofilters. International journal of systematic and evolutionary microbiology. 2012 Oct; 62(Pt 10):2511-2516. doi: 10.1099/ijs.0.038224-0. [PMID: 22155762]
  • A Srinivas, K Rahul, Ch Sasikala, Y Subhash, E V V Ramaprasad, Ch V Ramana. Georgenia satyanarayanai sp. nov., an alkaliphilic and thermotolerant amylase-producing actinobacterium isolated from a soda lake. International journal of systematic and evolutionary microbiology. 2012 Oct; 62(Pt 10):2405-2409. doi: 10.1099/ijs.0.036210-0. [PMID: 22140168]
  • Alejandro K Samhan-Arias, Jing Ji, Olga M Demidova, Louis J Sparvero, Weihong Feng, Vladimir Tyurin, Yulia Y Tyurina, Michael W Epperly, Anna A Shvedova, Joel S Greenberger, Hülya Bayır, Valerian E Kagan, Andrew A Amoscato. Oxidized phospholipids as biomarkers of tissue and cell damage with a focus on cardiolipin. Biochimica et biophysica acta. 2012 Oct; 1818(10):2413-23. doi: 10.1016/j.bbamem.2012.03.014. [PMID: 22464971]
  • Robin B Chan, Gilbert Di Paolo. Knockout punch: cardiolipin oxidation in trauma. Nature neuroscience. 2012 Oct; 15(10):1325-7. doi: 10.1038/nn.3222. [PMID: 23007184]
  • Sayuri Miyamoto, Iseli L Nantes, Priscila A Faria, Daniela Cunha, Graziella E Ronsein, Marisa H G Medeiros, Paolo Di Mascio. Cytochrome c-promoted cardiolipin oxidation generates singlet molecular oxygen. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 2012 Oct; 11(10):1536-46. doi: 10.1039/c2pp25119a. [PMID: 22814443]
  • Ziqiang Guan, Norah C Johnston, Christian R H Raetz, Eric A Johnson, Howard Goldfine. Lipid diversity among botulinum neurotoxin-producing clostridia. Microbiology (Reading, England). 2012 Oct; 158(Pt 10):2577-2584. doi: 10.1099/mic.0.060707-0. [PMID: 22837302]
  • Eugenia Kovács, Tudor Savopol, Maria-Minodora Iordache, Lavinia Săplăcan, Iuliana Sobaru, Claudia Istrate, Marie-Paule Mingeot-Leclercq, Mihaela-Georgeta Moisescu. Interaction of gentamicin polycation with model and cell membranes. Bioelectrochemistry (Amsterdam, Netherlands). 2012 Oct; 87(?):230-5. doi: 10.1016/j.bioelechem.2012.03.001. [PMID: 22522030]
  • Ismet Ara, Baljinova Tsetseg, Damdinsuren Daram, Manabu Suto, Katsuhiko Ando. Cryptosporangium mongoliense sp. nov., isolated from soil. International journal of systematic and evolutionary microbiology. 2012 Oct; 62(Pt 10):2480-2484. doi: 10.1099/ijs.0.038307-0. [PMID: 22140154]
  • Jing Ji, Anthony E Kline, Andrew Amoscato, Alejandro K Samhan-Arias, Louis J Sparvero, Vladimir A Tyurin, Yulia Y Tyurina, Bruno Fink, Mioara D Manole, Ava M Puccio, David O Okonkwo, Jeffrey P Cheng, Henry Alexander, Robert S B Clark, Patrick M Kochanek, Peter Wipf, Valerian E Kagan, Hülya Bayır. Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury. Nature neuroscience. 2012 Oct; 15(10):1407-13. doi: 10.1038/nn.3195. [PMID: 22922784]
  • Wen-Ming Chen, Yang-Shun Lin, Der-Shyan Sheu, Shih-Yi Sheu. Delftia litopenaei sp. nov., a poly-β-hydroxybutyrate-accumulating bacterium isolated from a freshwater shrimp culture pond. International journal of systematic and evolutionary microbiology. 2012 Oct; 62(Pt 10):2315-2321. doi: 10.1099/ijs.0.037507-0. [PMID: 22140156]
  • Chang-Muk Lee, Hang-Yeon Weon, Sang-Hong Yoon, Soo-Jin Kim, Bon-Sung Koo, Soon-Wo Kwon. Burkholderia denitrificans sp. nov., isolated from the soil of Dokdo Island, Korea. Journal of microbiology (Seoul, Korea). 2012 Oct; 50(5):855-9. doi: 10.1007/s12275-012-1554-2. [PMID: 23124756]
  • Rodrigo Arias-Cartin, Stéphane Grimaldi, Pascal Arnoux, Bruno Guigliarelli, Axel Magalon. Cardiolipin binding in bacterial respiratory complexes: structural and functional implications. Biochimica et biophysica acta. 2012 Oct; 1817(10):1937-49. doi: 10.1016/j.bbabio.2012.04.005. [PMID: 22561115]
  • Shailly Anand, Kiran Bala, Anjali Saxena, Peter Schumann, Rup Lal. Microbacterium amylolyticum sp. nov., isolated from soil from an industrial waste site. International journal of systematic and evolutionary microbiology. 2012 Sep; 62(Pt 9):2114-2120. doi: 10.1099/ijs.0.034439-0. [PMID: 22039005]
  • Silvia C Lopes, Cristina S Neves, Peter Eaton, Paula Gameiro. Improved model systems for bacterial membranes from differing species: the importance of varying composition in PE/PG/cardiolipin ternary mixtures. Molecular membrane biology. 2012 Sep; 29(6):207-17. doi: 10.3109/09687688.2012.700491. [PMID: 22830986]
  • Takashi Himoto, Hirohito Yoneyama, Kazutaka Kurokohchi, Hirohito Mori, Michio Inukai, Hisashi Masugata, Fuminori Goda, Reiji Haba, Seishiro Watanabe, Shoich Senda, Tsutomu Masaki. Clinical relevance of antibodies to cardiolipin in patients with chronic hepatitis C. Journal of clinical laboratory analysis. 2012 Sep; 26(5):342-8. doi: 10.1002/jcla.21529. [PMID: 23001979]
  • Muhammad Khan, Fei Yi, Azhar Rasul, Ting Li, Nan Wang, Hongwen Gao, Rong Gao, Tonghui Ma. Alantolactone induces apoptosis in glioblastoma cells via GSH depletion, ROS generation, and mitochondrial dysfunction. IUBMB life. 2012 Sep; 64(9):783-94. doi: 10.1002/iub.1068. [PMID: 22837216]
  • Alexa Frischmann, Alexander Knoll, Friederike Hilbert, Aleksandra Anna Zasada, Peter Kämpfer, Hans-Jürgen Busse. Corynebacterium epidermidicanis sp. nov., isolated from skin of a dog. International journal of systematic and evolutionary microbiology. 2012 Sep; 62(Pt 9):2194-2200. doi: 10.1099/ijs.0.036061-0. [PMID: 22081710]
  • Muaz Hijazin, Ellen Prenger-Berninghoff, Osama Sammra, Jörg Alber, Christoph Lämmler, Peter Kämpfer, Stefanie P Glaeser, Hans-Jürgen Busse, Abdulwahed Ahmed Hassan, Amir Abdulmawjood, Michael Zschöck. Arcanobacterium canis sp. nov., isolated from otitis externa of a dog, and emended description of the genus Arcanobacterium Collins et al. 1983 emend. Yassin et al. 2011. International journal of systematic and evolutionary microbiology. 2012 Sep; 62(Pt 9):2201-2205. doi: 10.1099/ijs.0.037150-0. [PMID: 22081713]
  • De-Chao Zhang, Hans-Jürgen Busse, Cornelia Wieser, Hong-Can Liu, Yu-Guang Zhou, Franz Schinner, Rosa Margesin. Candidimonas bauzanensis sp. nov., isolated from soil, and emended description of the genus Candidimonas Vaz-Moreira et al. 2011. International journal of systematic and evolutionary microbiology. 2012 Sep; 62(Pt 9):2084-2089. doi: 10.1099/ijs.0.036400-0. [PMID: 22039000]
  • Christine T Schwall, Victoria L Greenwood, Nathan N Alder. The stability and activity of respiratory Complex II is cardiolipin-dependent. Biochimica et biophysica acta. 2012 Sep; 1817(9):1588-96. doi: 10.1016/j.bbabio.2012.04.015. [PMID: 22575443]
  • Shih-Yi Sheu, Jui-Hsing Chou, Cyril Bontemps, Geoffrey N Elliott, Eduardo Gross, Euan K James, Janet I Sprent, J Peter W Young, Wen-Ming Chen. Burkholderia symbiotica sp. nov., isolated from root nodules of Mimosa spp. native to north-east Brazil. International journal of systematic and evolutionary microbiology. 2012 Sep; 62(Pt 9):2272-2278. doi: 10.1099/ijs.0.037408-0. [PMID: 22081715]
  • Pei-Hsiu Kao, Shinne-Ren Lin, Wan-Ping Hu, Long-Sen Chang. Naja naja atra and Naja nigricollis cardiotoxins induce fusion of Escherichia coli and Staphylococcus aureus membrane-mimicking liposomes. Toxicon : official journal of the International Society on Toxinology. 2012 Sep; 60(3):367-77. doi: 10.1016/j.toxicon.2012.04.345. [PMID: 22569319]
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  • Muaz Hijazin, Jörg Alber, Christoph Lämmler, Peter Kämpfer, Stefanie P Glaeser, Hans-Jürgen Busse, Johannes Kassmannhuber, Ellen Prenger-Berninghoff, Thorsten Förnges, Abdulwahed Ahmed Hassan, Amir Abdulmawjood, Michael Zschöck. Actinomyces weissii sp. nov., isolated from dogs. International journal of systematic and evolutionary microbiology. 2012 Aug; 62(Pt 8):1755-1760. doi: 10.1099/ijs.0.035626-0. [PMID: 21948094]
  • Jyoti Swaroop Kumar, Shubhankar Suman, Vijaypal Singh, Sudhir Chandna. Radioresistant Sf9 insect cells display moderate resistance against cumene hydroperoxide. Molecular and cellular biochemistry. 2012 Aug; 367(1-2):141-51. doi: 10.1007/s11010-012-1327-6. [PMID: 22555957]
  • Pankyung Kim, Jae-Chan Lee, Dong-Jin Park, Kee-Sun Shin, Jeong-Yoon Kim, Chang-Jin Kim. Gracilibacillus bigeumensis sp. nov., a moderately halophilic bacterium from solar saltern soil. International journal of systematic and evolutionary microbiology. 2012 Aug; 62(Pt 8):1857-1863. doi: 10.1099/ijs.0.034264-0. [PMID: 21984665]
  • Paulo R G de Freitas-Junior, Carolina M C Catta-Preta, Iamara da Silva Andrade, Danielle P Cavalcanti, Wanderley de Souza, Marcelo Einicker-Lamas, Maria Cristina M Motta. Effects of miltefosine on the proliferation, ultrastructure, and phospholipid composition of Angomonas deanei, a trypanosomatid protozoan that harbors a symbiotic bacterium. FEMS microbiology letters. 2012 Aug; 333(2):129-37. doi: 10.1111/j.1574-6968.2012.02607.x. [PMID: 22651853]
  • Yinon Shapira, Nancy Agmon-Levin, Carlo Selmi, Jana Petríková, Ori Barzilai, Maya Ram, Nicola Bizzaro, Gabriele Valentini, Marco Matucci-Cerinic, Juan-Manuel Anaya, Bat-sheva Porat Katz, Yehuda Shoenfeld. Prevalence of anti-Toxoplasma antibodies in patients with autoimmune diseases. Journal of autoimmunity. 2012 Aug; 39(1-2):112-6. doi: 10.1016/j.jaut.2012.01.001. [PMID: 22297145]
  • Soon Dong Lee. Labedaea rhizosphaerae gen. nov., sp. nov., isolated from rhizosphere soil. International journal of systematic and evolutionary microbiology. 2012 Aug; 62(Pt 8):1772-1778. doi: 10.1099/ijs.0.034355-0. [PMID: 21948095]
  • Moriyuki Hamada, Tomohiko Tamura, Hideki Yamamura, Ken-Ichiro Suzuki, Masayuki Hayakawa. Lysinimicrobium mangrovi gen. nov., sp. nov., an actinobacterium isolated from the rhizosphere of a mangrove. International journal of systematic and evolutionary microbiology. 2012 Aug; 62(Pt 8):1731-1735. doi: 10.1099/ijs.0.035493-0. [PMID: 21930679]
  • Lucia Catucci, Vincenzo De Leo, Francesco Milano, Livia Giotta, Rita Vitale, Angela Agostiano, Angela Corcelli. Oxidoreductase activity of chromatophores and purified cytochrome bc1 complex from Rhodobacter sphaeroides: a possible role of cardiolipin. Journal of bioenergetics and biomembranes. 2012 Aug; 44(4):487-93. doi: 10.1007/s10863-012-9447-y. [PMID: 22733014]
  • Manar Aoun, Gilles Fouret, Françoise Michel, Béatrice Bonafos, Jeanne Ramos, Jean-Paul Cristol, Marie-Annette Carbonneau, Charles Coudray, Christine Feillet-Coudray. Dietary fatty acids modulate liver mitochondrial cardiolipin content and its fatty acid composition in rats with non alcoholic fatty liver disease. Journal of bioenergetics and biomembranes. 2012 Aug; 44(4):439-52. doi: 10.1007/s10863-012-9448-x. [PMID: 22689144]
  • Saowapar Khianngam, Somboon Tanasupawat, Ancharida Akaracharanya, Kwang Kyu Kim, Keun Chul Lee, Jung-Sook Lee. Cohnella cellulosilytica sp. nov., isolated from buffalo faeces. International journal of systematic and evolutionary microbiology. 2012 Aug; 62(Pt 8):1921-1925. doi: 10.1099/ijs.0.032607-0. [PMID: 22003039]
  • Wonyong Kim, Jitsopin Traiwan, Mi-Hak Park, Min Young Jung, Su-Jin Oh, Jung-Hoon Yoon, Ampaitip Sukhoom. Chungangia koreensis gen. nov., sp. nov., isolated from marine sediment. International journal of systematic and evolutionary microbiology. 2012 Aug; 62(Pt 8):1914-1920. doi: 10.1099/ijs.0.028837-0. [PMID: 21984680]
  • V Venkata Ramana, S Kalyana Chakravarthy, P Shalem Raj, B Vinay Kumar, E Shobha, E V V Ramaprasad, Ch Sasikala, Ch V Ramana. Descriptions of Rhodopseudomonas parapalustris sp. nov., Rhodopseudomonas harwoodiae sp. nov. and Rhodopseudomonas pseudopalustris sp. nov., and emended description of Rhodopseudomonas palustris. International journal of systematic and evolutionary microbiology. 2012 Aug; 62(Pt 8):1790-1798. doi: 10.1099/ijs.0.026815-0. [PMID: 21986724]
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  • Rosa Margesin, De-Chao Zhang, Hans-Jürgen Busse. Sphingomonas alpina sp. nov., a psychrophilic bacterium isolated from alpine soil. International journal of systematic and evolutionary microbiology. 2012 Jul; 62(Pt 7):1558-1563. doi: 10.1099/ijs.0.035964-0. [PMID: 21856979]
  • Sung-Geun Woo, Yingshun Cui, Myung-Suk Kang, Long Jin, Kwang Kyu Kim, Sung-Taik Lee, Myungjin Lee, Joonhong Park. Georgenia daeguensis sp. nov., isolated from 4-chlorophenol enrichment culture. International journal of systematic and evolutionary microbiology. 2012 Jul; 62(Pt 7):1703-1709. doi: 10.1099/ijs.0.033217-0. [PMID: 21930682]
  • Ming-Hui Chen, Shih-Yi Sheu, Chaolun Allen Chen, Jih-Terng Wang, Wen-Ming Chen. Idiomarina aquimaris sp. nov., isolated from the reef-building coral Isopora palifera. International journal of systematic and evolutionary microbiology. 2012 Jul; 62(Pt 7):1536-1542. doi: 10.1099/ijs.0.035592-0. [PMID: 21856977]
  • Ali Makhdoumi-Kakhki, Mohammad Ali Amoozegar, Antonio Ventosa. Salinibacter iranicus sp. nov. and Salinibacter luteus sp. nov., isolated from a salt lake, and emended descriptions of the genus Salinibacter and of Salinibacter ruber. International journal of systematic and evolutionary microbiology. 2012 Jul; 62(Pt 7):1521-1527. doi: 10.1099/ijs.0.031971-0. [PMID: 21856978]
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  • Eugenia Mileykovskaya, Pawel A Penczek, Jia Fang, Venkata K P S Mallampalli, Genevieve C Sparagna, William Dowhan. Arrangement of the respiratory chain complexes in Saccharomyces cerevisiae supercomplex III2IV2 revealed by single particle cryo-electron microscopy. The Journal of biological chemistry. 2012 Jun; 287(27):23095-103. doi: 10.1074/jbc.m112.367888. [PMID: 22573332]
  • Huiyong Yin, Aurélia Vergeade, Qiong Shi, William E Zackert, Katherine C Gruenberg, Magdalena Bokiej, Taneem Amin, Weizhen Ying, Tina S Masterson, Sandra S Zinkel, John A Oates, Olivier Boutaud, L Jackson Roberts. Acetaminophen inhibits cytochrome c redox cycling induced lipid peroxidation. Biochemical and biophysical research communications. 2012 Jun; 423(2):224-8. doi: 10.1016/j.bbrc.2012.05.058. [PMID: 22634010]
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  • Marcia Perez dos Santos Cabrera, Manoel Arcisio-Miranda, Renata Gorjão, Natália Bueno Leite, Bibiana Monson de Souza, Rui Curi, Joaquim Procopio, João Ruggiero Neto, Mario Sérgio Palma. Influence of the bilayer composition on the binding and membrane disrupting effect of Polybia-MP1, an antimicrobial mastoparan peptide with leukemic T-lymphocyte cell selectivity. Biochemistry. 2012 Jun; 51(24):4898-908. doi: 10.1021/bi201608d. [PMID: 22630563]
  • Ming-Hui Chen, Shih-Yi Sheu, Chaolun Allen Chen, Jih-Terng Wang, Wen-Ming Chen. Roseivivax isoporae sp. nov., isolated from a reef-building coral, and emended description of the genus Roseivivax. International journal of systematic and evolutionary microbiology. 2012 Jun; 62(Pt 6):1259-1264. doi: 10.1099/ijs.0.032961-0. [PMID: 21764981]
  • Thomas Obsen, Nils J Faergeman, Soonkyu Chung, Kristina Martinez, Semone Gobern, Olivier Loreau, Martin Wabitsch, Susanne Mandrup, Michael McIntosh. Trans-10, cis-12 conjugated linoleic acid decreases de novo lipid synthesis in human adipocytes. The Journal of nutritional biochemistry. 2012 Jun; 23(6):580-90. doi: 10.1016/j.jnutbio.2011.02.014. [PMID: 21775116]
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  • Eun Mi Choi. Magnolol protects osteoblastic MC3T3-E1 cells against antimycin A-induced cytotoxicity through activation of mitochondrial function. Inflammation. 2012 Jun; 35(3):1204-12. doi: 10.1007/s10753-012-9430-0. [PMID: 22281543]
  • Christopher M Mulligan, Genevieve C Sparagna, Catherine H Le, Anthony B De Mooy, Melissa A Routh, Michael G Holmes, Diane L Hickson-Bick, Simona Zarini, Robert C Murphy, Fred Y Xu, Grant M Hatch, Sylvia A McCune, Russell L Moore, Adam J Chicco. Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart. Cardiovascular research. 2012 Jun; 94(3):460-8. doi: 10.1093/cvr/cvs118. [PMID: 22411972]
  • Peter Kämpfer, A B Arun, Chiu-Chung Young, Hans-Jürgen Busse, Johannes Kassmannhuber, Ramon Rosselló-Móra, Birgit Geueke, P D Rekha, Wen-Ming Chen. Sphingomicrobium lutaoense gen. nov., sp. nov., isolated from a coastal hot spring. International journal of systematic and evolutionary microbiology. 2012 Jun; 62(Pt 6):1326-1330. doi: 10.1099/ijs.0.034413-0. [PMID: 21828023]
  • Tuan Hoang, Matthew D Smith, Masoud Jelokhani-Niaraki. Toward understanding the mechanism of ion transport activity of neuronal uncoupling proteins UCP2, UCP4, and UCP5. Biochemistry. 2012 May; 51(19):4004-14. doi: 10.1021/bi3003378. [PMID: 22524567]
  • Nobuo N Noda, Takafumi Kobayashi, Wakana Adachi, Yuko Fujioka, Yoshinori Ohsumi, Fuyuhiko Inagaki. Structure of the novel C-terminal domain of vacuolar protein sorting 30/autophagy-related protein 6 and its specific role in autophagy. The Journal of biological chemistry. 2012 May; 287(20):16256-66. doi: 10.1074/jbc.m112.348250. [PMID: 22437838]
  • Wen-Ming Chen, Shwu-Harn Yang, Wei-Cheng Huang, Chih-Yu Cheng, Shih-Yi Sheu. Chitinivorax tropicus gen. nov., sp. nov., a chitinolytic bacterium isolated from a freshwater lake. International journal of systematic and evolutionary microbiology. 2012 May; 62(Pt 5):1086-1091. doi: 10.1099/ijs.0.031310-0. [PMID: 21705448]
  • Camilla L Nesbø, Danielle M Bradnan, Abigail Adebusuyi, Marlena Dlutek, Amanda K Petrus, Julia Foght, W Ford Doolittle, Kenneth M Noll. Mesotoga prima gen. nov., sp. nov., the first described mesophilic species of the Thermotogales. Extremophiles : life under extreme conditions. 2012 May; 16(3):387-93. doi: 10.1007/s00792-012-0437-0. [PMID: 22411358]
  • Amador Goodridge, Carla Cueva, Maureen Lahiff, Grace Muzanye, John L Johnson, Payam Nahid, Lee W Riley. Anti-phospholipid antibody levels as biomarker for monitoring tuberculosis treatment response. Tuberculosis (Edinburgh, Scotland). 2012 May; 92(3):243-7. doi: 10.1016/j.tube.2012.02.004. [PMID: 22406155]
  • Wen-Ming Chen, Fu-Sian Sheu, Chiu-Chung Young, Shih-Yi Sheu. Inhella fonticola sp. nov., isolated from spring water, and emended description of the genus Inhella. International journal of systematic and evolutionary microbiology. 2012 May; 62(Pt 5):1048-1055. doi: 10.1099/ijs.0.034884-0. [PMID: 21685252]
  • Mi-Hak Park, Jitsopin Traiwan, Min Young Jung, Wonyong Kim. Gulosibacter chungangensis sp. nov., an actinomycete isolated from a marine sediment, and emended description of the genus Gulosibacter. International journal of systematic and evolutionary microbiology. 2012 May; 62(Pt 5):1055-1060. doi: 10.1099/ijs.0.032268-0. [PMID: 21685251]
  • Valeriya M Trusova, Elena Kirilova, Inta Kalnina, Georgiy Kirilov, Olga A Zhytniakivska, Pavel V Fedorov, Galyna P Gorbenko. Novel benzanthrone aminoderivatives for membrane studies. Journal of fluorescence. 2012 May; 22(3):953-9. doi: 10.1007/s10895-011-1035-8. [PMID: 22218973]
  • Zhen Xu, Qingyan Xu, Zhonghui Zheng, Yaojian Huang. Kribbella amoyensis sp. nov., isolated from rhizosphere soil of a pharmaceutical plant, Typhonium giganteum Engl. International journal of systematic and evolutionary microbiology. 2012 May; 62(Pt 5):1081-1085. doi: 10.1099/ijs.0.033290-0. [PMID: 21705443]
  • Jin-Ha Lee, Sang-Seob Lee. Leucobacter margaritiformis sp. nov., isolated from bamboo extract. Current microbiology. 2012 May; 64(5):441-8. doi: 10.1007/s00284-012-0089-4. [PMID: 22349954]
  • P Kämpfer, H C Scholz, N Lodders, I Loncaric, A M Whatmore, H-J Busse. Camelimonas abortus sp. nov., isolated from placental tissue of cattle. International journal of systematic and evolutionary microbiology. 2012 May; 62(Pt 5):1117-1120. doi: 10.1099/ijs.0.034389-0. [PMID: 21724960]
  • Roberto Angelini, Paulina Corral, Patrizia Lopalco, Antonio Ventosa, Angela Corcelli. Novel ether lipid cardiolipins in archaeal membranes of extreme haloalkaliphiles. Biochimica et biophysica acta. 2012 May; 1818(5):1365-73. doi: 10.1016/j.bbamem.2012.02.014. [PMID: 22366205]
  • Victoria Lewis, Cathryn L Haigh, Colin L Masters, Andrew F Hill, Victoria A Lawson, Steven J Collins. Prion subcellular fractionation reveals infectivity spectrum, with a high titre-low PrPres level disparity. Molecular neurodegeneration. 2012 Apr; 7(?):18. doi: 10.1186/1750-1326-7-18. [PMID: 22534096]
  • Pedro F Almaida-Pagán, Jorge de Costa, Pilar Mendiola, Douglas R Tocher. Changes in tissue and mitochondrial membrane composition during rapid growth, maturation and aging in rainbow trout, Oncorhynchus mykiss. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2012 Apr; 161(4):404-12. doi: 10.1016/j.cbpb.2012.01.006. [PMID: 22281523]
  • Yasmeen Maniyar, Prabhu Bhixavatimath. Antihyperglycemic and hypolipidemic activities of aqueous extract of Carica papaya Linn. leaves in alloxan-induced diabetic rats. Journal of Ayurveda and integrative medicine. 2012 Apr; 3(2):70-4. doi: 10.4103/0975-9476.96519. [PMID: 22707862]
  • Graham P Holloway, Val Andrew Fajardo, Lauren McMeekin, Paul J LeBlanc. Unsaturation of mitochondrial membrane lipids is related to palmitate oxidation in subsarcolemmal and intermyofibrillar mitochondria. The Journal of membrane biology. 2012 Apr; 245(4):165-76. doi: 10.1007/s00232-012-9426-6. [PMID: 22527602]
  • Hyangmi Kim, Hyun-Woo Oh, Doo-Sang Park, Kang Hyun Lee, Sung Uk Kim, Hee-Moon Park, Kyung Sook Bae. Phycicoccus ochangensis sp. nov., isolated from soil of a potato cultivation field. Journal of microbiology (Seoul, Korea). 2012 Apr; 50(2):349-53. doi: 10.1007/s12275-012-1206-6. [PMID: 22538666]
  • Kadriye Inan, Sabriye Canakci, Ali Osman Belduz, Fikrettin Sahin. Brevibacillus aydinogluensis sp. nov., a moderately thermophilic bacterium isolated from Karakoc hot spring. International journal of systematic and evolutionary microbiology. 2012 Apr; 62(Pt 4):849-855. doi: 10.1099/ijs.0.031914-0. [PMID: 21622837]
  • Soon Dong Lee. Actinomadura rupiterrae sp. nov., isolated from cliff soil. International journal of systematic and evolutionary microbiology. 2012 Apr; 62(Pt 4):990-995. doi: 10.1099/ijs.0.035121-0. [PMID: 21685258]
  • Silke Karojet, Sabine Kunz, Joost T van Dongen. Microbacterium yannicii sp. nov., isolated from Arabidopsis thaliana roots. International journal of systematic and evolutionary microbiology. 2012 Apr; 62(Pt 4):822-826. doi: 10.1099/ijs.0.026955-0. [PMID: 21571929]
  • Christopher Stroupe. The yeast vacuolar Rab GTPase Ypt7p has an activity beyond membrane recruitment of the homotypic fusion and protein sorting-Class C Vps complex. The Biochemical journal. 2012 Apr; 443(1):205-11. doi: 10.1042/bj20110687. [PMID: 22417749]
  • Anna Kastorna, Valeriya Trusova, Galyna Gorbenko, Paavo Kinnunen. Membrane effects of lysozyme amyloid fibrils. Chemistry and physics of lipids. 2012 Apr; 165(3):331-7. doi: 10.1016/j.chemphyslip.2012.02.002. [PMID: 22406142]
  • M Bagheri, M Didari, M A Amoozegar, P Schumann, C Sánchez-Porro, M Mehrshad, A Ventosa. Bacillus iranensis sp. nov., a moderate halophile from a hypersaline lake. International journal of systematic and evolutionary microbiology. 2012 Apr; 62(Pt 4):811-816. doi: 10.1099/ijs.0.030874-0. [PMID: 21571930]
  • Young-Ok Kim, Hee Jeong Kong, Sooyeon Park, So-Jung Kang, Woo-Jin Kim, Kyung-Kil Kim, Tae-Kwang Oh, Jung-Hoon Yoon. Roseovarius halocynthiae sp. nov., isolated from the sea squirt Halocynthia roretzi. International journal of systematic and evolutionary microbiology. 2012 Apr; 62(Pt 4):931-936. doi: 10.1099/ijs.0.031674-0. [PMID: 21669917]
  • Moriyuki Hamada, Chiaki Komukai, Tomohiko Tamura, Lyudmila I Evtushenko, Natalia G Vinokurova, Ken-Ichiro Suzuki. Description of Herbiconiux flava sp. nov. and emended description of the genus Herbiconiux. International journal of systematic and evolutionary microbiology. 2012 Apr; 62(Pt 4):795-799. doi: 10.1099/ijs.0.031260-0. [PMID: 21571941]
  • Zhi Huang, Xia-Fang Sheng, Fei Zhao, Lin-Yan He, Jing Huang, Qi Wang. Isoptericola nanjingensis sp. nov., a mineral-weathering bacterium. International journal of systematic and evolutionary microbiology. 2012 Apr; 62(Pt 4):971-976. doi: 10.1099/ijs.0.033043-0. [PMID: 21669920]
  • Marta Kicia, Natalia Janeczko, Jagoda Lewicka, Andrzej B Hendrich. Comparison of the effects of subinhibitory concentrations of ciprofloxacin and colistin on the morphology of cardiolipin domains in Escherichia coli membranes. Journal of medical microbiology. 2012 Apr; 61(Pt 4):520-524. doi: 10.1099/jmm.0.037788-0. [PMID: 22160313]
  • Keshao Liu, Rui Zong, Qipei Li, Yingnan Fu, Yongle Xu, Yanan Wang, Nianzhi Jiao. Oceaniovalibus guishaninsula gen. nov., sp. nov., a marine bacterium of the family Rhodobacteraceae. Current microbiology. 2012 Apr; 64(4):385-91. doi: 10.1007/s00284-012-0081-z. [PMID: 22278760]
  • Yu Zhou, Xiaoyun Chen, Yu Zhang, Wei Wang, Junfeng Xu. Description of Sinomonas soli sp. nov., reclassification of Arthrobacter echigonensis and Arthrobacter albidus (Ding et al. 2009) as Sinomonas echigonensis comb. nov. and Sinomonas albida comb. nov., respectively, and emended description of the genus Sinomonas. International journal of systematic and evolutionary microbiology. 2012 Apr; 62(Pt 4):764-769. doi: 10.1099/ijs.0.030361-0. [PMID: 21571934]