Clobetasone butyrate (BioDeep_00000511325)
代谢物信息卡片
化学式: C26H32ClFO5 (478.1922184)
中文名称: 丁酸氯倍他松, 倍他松丁酸酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCC(=O)OC1(C(CC2C1(CC(=O)C3(C2CCC4=CC(=O)C=CC43C)F)C)C)C(=O)CCl
InChI: InChI=1S/C26H32ClFO5/c1-5-6-22(32)33-26(21(31)14-27)15(2)11-19-18-8-7-16-12-17(29)9-10-23(16,3)25(18,28)20(30)13-24(19,26)4/h9-10,12,15,18-19H,5-8,11,13-14H2,1-4H3/t15-,18-,19-,23-,24-,25-,26-/m0/s1
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
D000893 - Anti-Inflammatory Agents
同义名列表
2 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:31415
- KEGGdrug: D01273
- PubChem: 71386
- Metlin: METLIN1868
- ChEMBL: CHEMBL577673
- CAS: 25122-57-0
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Kei Nakayama, Yoshiyuki Inoue, Naomi Ikeda, Naoki Hashizume, Hidekazu Murakami, Takeshi Ishibashi, Hirofumi Ikeda, Tomohiko Isobe, Shin-Ichi Kitamura, Go Suzuki. Uptake and biological effects of synthetic glucocorticoids in common carp (Cyprinus carpio).
Marine pollution bulletin.
2014 Aug; 85(2):370-5. doi:
10.1016/j.marpolbul.2014.01.042. [PMID: 24492153] - Ilknur Bostanci, Ozlem Atli, Nermin Celebi, Ayşin Taşar, Esra Alpkarakoç, Yildiz Dallar. Serum leptin level in children with atopic dermatitis-treated topical steroids.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.
2004 Jun; 15(3):267-9. doi:
10.1111/j.1399-3038.2004.00145.x. [PMID: 15209961] - A Tang, N David, L W Horton. Plasma cell balanitis of Zoon: response to Trimovate cream.
International journal of STD & AIDS.
2001 Feb; 12(2):75-8. doi:
10.1258/0956462011916811. [PMID: 11236107] - A Wolkerstorfer, M A Strobos, E J Glazenburg, P G Mulder, A P Oranje. Fluticasone propionate 0.05\% cream once daily versus clobetasone butyrate 0.05\% cream twice daily in children with atopic dermatitis.
Journal of the American Academy of Dermatology.
1998 Aug; 39(2 Pt 1):226-31. doi:
10.1016/s0190-9622(98)70080-5. [PMID: 9704834] - D Bleidl, C Occella, L Schiazza, E Rampini. [Eudermic activity of 2 dermo-protective products on the skin of the atopic child].
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia.
1988 Apr; 123(4):XIX-XXII. doi:
". [PMID: 3182000] - A L Boner, C Richelli, G De Stefano, E A Valletta, S Ferrari, M Mengoni. Hypothalamic-pituitary-adrenal function in children with atopic dermatitis treated with clobetasone butyrate and its clinical evaluation.
International journal of clinical pharmacology, therapy, and toxicology.
1985 Feb; 23(2):118-20. doi:
NULL. [PMID: 2985514] - C Queille, R Pommarede, J H Saurat. Efficacy versus systemic effects of six topical steroids in the treatment of atopic dermatitis of childhood.
Pediatric dermatology.
1984 Jan; 1(3):246-53. doi:
10.1111/j.1525-1470.1984.tb01124.x. [PMID: 6494068] - J Tamura, N Sato, T Moriwaki, A Tatami, H Ezaki, R Nagasawa, M Aoishi, C Okamura, M Sutoh, T Bando, M Matsumoto, K Hashimoto. [Studies on toxicity of clobetasone-17-butyrate (II)--chronic toxicity in rats (author's transl)].
The Journal of toxicological sciences.
1980 May; 5(2):177-201. doi:
10.2131/jts.5.177. [PMID: 7452742] - J Tamura, N Sato, T Moriwaki, A Tatami, H Ezaki, R Nagasawawa, M Aoishi, C Okamura, M Sutoh, T Bando, K Hashimoto, M Matsumoto. [Studies on toxicity of clobetasone-17-butyrate (I)--acute toxicity in mice and rats and subacute toxicity in rats (author's transl)].
The Journal of toxicological sciences.
1980 Feb; 5(1):45-78. doi:
10.2131/jts.5.45. [PMID: 7431440]