Questiomycin A (BioDeep_00000004860)

 

Secondary id: BioDeep_00001868452

human metabolite Endogenous blood metabolite Volatile Flavor Compounds


代谢物信息卡片


2-Acetylamino-(3H)-phenoxazin-3-one

化学式: C12H8N2O2 (212.0585748)
中文名称:
谱图信息: 最多检出来源 Macaca mulatta(otcml) 0.69%

分子结构信息

SMILES: C1=CC=C2C(=C1)N=C3C=C(C(=O)C=C3O2)N
InChI: InChI=1S/C12H8N2O2/c13-7-5-9-12(6-10(7)15)16-11-4-2-1-3-8(11)14-9/h1-6H,13H2

描述信息

Questiomycin A, also known as 2-aminophenoxazin-3-one (APO), is found in mushrooms such as Calocybe gambosa (St Georges mushroom). 2-Aminophenoxazin-3-one is a benzoxazinoid metabolite. It was found excreted in the feces of rats that were fed a rye bread-based diet which makes this compound a potential fecal biomarker of whole grain intake (PMID: 23113707).

同义名列表

17 个代谢物同义名

2-Acetylamino-(3H)-phenoxazin-3-one; Acrospermum viticola toxin C; 2-Amino-3H-phenoxazin-3-one; 2-Aminophenoxazine-3-one; 2-Amino-phenoxazin-3-one; 2-Aminophenoxazin-3-one; 2-Amino-3-phenoxazone; 2-Aminophenoxazone; 3-Aminophenoxazone; 2-Aminophenoxazon; Questinomycine a; Questiomycin A; Isophenoxazine; AV toxin C; NSC 94945; PHX-3 CPD; 2-Aminophenoxazin-3-one



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Shuqi Guo, Hongbo Hu, Wei Wang, Muhammad Bilal, Xuehong Zhang. Production of Antibacterial Questiomycin A in Metabolically Engineered Pseudomonas chlororaphis HT66. Journal of agricultural and food chemistry. 2022 Jun; 70(25):7742-7750. doi: 10.1021/acs.jafc.2c03216. [PMID: 35708224]
  • Sascha Venturelli, Regina G Belz, Andreas Kämper, Alexander Berger, Kyra von Horn, André Wegner, Alexander Böcker, Gérald Zabulon, Tobias Langenecker, Oliver Kohlbacher, Fredy Barneche, Detlef Weigel, Ulrich M Lauer, Michael Bitzer, Claude Becker. Plants Release Precursors of Histone Deacetylase Inhibitors to Suppress Growth of Competitors. The Plant cell. 2015 Nov; 27(11):3175-89. doi: 10.1105/tpc.15.00585. [PMID: 26530086]
  • Hisashi Kato-Noguchi, Francisco A Macías, José M G Molinillo. Structure-activity relationship of benzoxazinones and related compounds with respect to the growth inhibition and alpha-amylase activity in cress seedlings. Journal of plant physiology. 2010 Oct; 167(15):1221-5. doi: 10.1016/j.jplph.2010.04.006. [PMID: 20605653]
  • Shusheng Zhang, Xuemei Li, Fan Zhang. CE-based simultaneous liquid-phase noncompetitive enzyme immunoassay for three tumor markers in human serum using electrochemical detection. Electrophoresis. 2007 Dec; 28(23):4427-34. doi: 10.1002/elps.200700026. [PMID: 17979157]
  • Naoko Miyano-Kurosaki, Kunihiko Kurosaki, Michiko Hayashi, Hiroshi Takaku, Masaaki Hayafune, Ken Shirato, Teruhiko Kasuga, Takahiko Endo, Akio Tomoda. 2-aminophenoxazine-3-one suppresses the growth of mouse malignant melanoma B16 cells transplanted into C57BL/6Cr Slc mice. Biological & pharmaceutical bulletin. 2006 Nov; 29(11):2197-201. doi: 10.1248/bpb.29.2197. [PMID: 17077514]
  • Stefan Martyniuk, Anna Stochmal, Francisco A Macías, David Marín, Wieslaw Oleszek. Effects of some benzoxazinoids on in vitro growth of Cephalosporium gramineum and other fungi pathogenic to cereals and on Cephalosporium stripe of winter wheat. Journal of agricultural and food chemistry. 2006 Feb; 54(4):1036-9. doi: 10.1021/jf050901x. [PMID: 16478214]
  • Mia B Gents, Susan T Nielsen, Anne G Mortensen, Carsten Christophersen, Inge S Fomsgaard. Transformation products of 2-benzoxazolinone (BOA) in soil. Chemosphere. 2005 Sep; 61(1):74-84. doi: 10.1016/j.chemosphere.2005.03.068. [PMID: 15876449]
  • Francisco A Macías, David Marín, Alberto Oliveros-Bastidas, Diego Castellano, Ana M Simonet, José M G Molinillo. Structure-Activity Relationships (SAR) studies of benzoxazinones, their degradation products and analogues. phytotoxicity on standard target species (STS). Journal of agricultural and food chemistry. 2005 Feb; 53(3):538-48. doi: 10.1021/jf0484071. [PMID: 15686399]