Cefodizime (BioDeep_00000481685)

   


代谢物信息卡片


7-(((2-Amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid

化学式: C20H20N6O7S4 (584.027629)
中文名称: 头孢地嗪酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C(SC(=N1)SCC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)O)CC(=O)O
InChI: InChI=1S/C20H20N6O7S4/c1-7-10(3-11(27)28)37-20(22-7)36-5-8-4-34-17-13(16(30)26(17)14(8)18(31)32)24-15(29)12(25-33-2)9-6-35-19(21)23-9/h6,13,17H,3-5H2,1-2H3,(H2,21,23)(H,24,29)(H,27,28)(H,31,32)/b25-12+

描述信息

A cephalosporin compound having 5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups located at positions 3 and 7 respectively.
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01D - Other beta-lactam antibacterials > J01DD - Third-generation cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic

同义名列表

2 个代谢物同义名

Cefodizime; 7-(((2-Amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Lihong Li, Baozhong Ren, Jian Guo, Zhicang Zhang, Yuxing Cai, Jie Yin. Expression levels of blood platelet and C-reactive protein in patients with severely pneumonic and their predictive values for efficacy. Cellular and molecular biology (Noisy-le-Grand, France). 2020 May; 66(2):105-110. doi: 10.14715/cmb/2020.66.2.17. [PMID: 32415935]
  • Bin Wang, Ruimin Bian, Chuanmei Wei, Shaowei Sun, Peimin Gao. [Cefodizime increases peripheral blood CD4/CD8 and Th1/Th2 ratios in senile patients with bacterial pneumonia]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 2015 Apr; 31(4):528-31. doi: . [PMID: 25854575]
  • Taoying Hu, Ying Liu. Probing the interaction of cefodizime with human serum albumin using multi-spectroscopic and molecular docking techniques. Journal of pharmaceutical and biomedical analysis. 2015 Mar; 107(?):325-32. doi: 10.1016/j.jpba.2015.01.010. [PMID: 25637820]
  • Iftekhar Mahmood, John Duan. Population pharmacokinetics with a very small sample size. Drug metabolism and drug interactions. 2009; 24(2-4):259-74. doi: 10.1515/dmdi.2009.24.2-4.259. [PMID: 20408503]
  • R Scott Obach, Franco Lombardo, Nigel J Waters. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals. 2008 Jul; 36(7):1385-405. doi: 10.1124/dmd.108.020479. [PMID: 18426954]
  • Brigitte Meyer, Friederike Traunmueller, Andja Bojic, Gottfried Locker, Rainer Schmid, Stefan Winkler, Florian Thalhammer. Single-dose pharmacokinetics of cefodizime in critically ill elderly patients. International journal of antimicrobial agents. 2006 Apr; 27(4):335-8. doi: 10.1016/j.ijantimicag.2005.11.018. [PMID: 16563704]
  • Petra Luckner, Matthias Brandsch. Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2005 Jan; 59(1):17-24. doi: 10.1016/j.ejpb.2004.07.008. [PMID: 15567297]
  • Masato Horikawa, Yukio Kato, Charles A Tyson, Yuichi Sugiyama. The potential for an interaction between MRP2 (ABCC2) and various therapeutic agents: probenecid as a candidate inhibitor of the biliary excretion of irinotecan metabolites. Drug metabolism and pharmacokinetics. 2002; 17(1):23-33. doi: 10.2133/dmpk.17.23. [PMID: 15618649]
  • E Fiaccadori, U Maggiore, A Arisi, A Cabassi, C Beghi, R Campodonico, T Gherli. Outbreak of acute renal failure due to cefodizime-vancomycin association in a heart surgery unit. Intensive care medicine. 2001 Nov; 27(11):1819-22. doi: 10.1007/s00134-001-1123-3. [PMID: 11810128]
  • G Blandino, I Milazzo, R Musumeci, V M Nicolosi, A Speciale, G Nicoletti. Comparative activity of cefodizime and ceftriaxone against respiratory pathogens in an in vitro pharmacodynamic model simulating concentration-time curves. Journal of chemotherapy (Florence, Italy). 2000 Dec; 12(6):503-8. doi: 10.1179/joc.2000.12.6.503. [PMID: 11154034]
  • T Mazzei, A Novelli, S Esposito, S Fallani, S Noviello, M I Cassetta, S Conti, P Periti. Cefodizime in skin suction blister fluid and serum following a single intravenous or intramuscular dose in adult patients. Journal of chemotherapy (Florence, Italy). 2000 Aug; 12(4):306-13. doi: 10.1179/joc.2000.12.4.306. [PMID: 10949980]
  • P C Braga, M Dal Sasso, L Mancini, M T Sala. Influence of sub-minimum inhibitory concentrations of cefodizime on the phagocytosis, intracellular killing and oxidative bursts of human polymorphonuclear leukocytes. Chemotherapy. 1999 May; 45(3):166-74. doi: 10.1159/000007179. [PMID: 10224338]
  • A Loffreda, E Lampa, C Lucarelli, M Amorena, C Contaldi, V Calderaro, F Rossi. Pharmacokinetics of cefodizime in patients with various degrees of renal failure. Chemotherapy. 1999 Jan; 45(1):1-7. doi: 10.1159/000007158. [PMID: 9876203]
  • M Müller, B Rohde, A Kovar, A Georgopoulos, H G Eichler, H Derendorf. Relationship between serum and free interstitial concentrations of cefodizime and cefpirome in muscle and subcutaneous adipose tissue of healthy volunteers measured by microdialysis. Journal of clinical pharmacology. 1997 Dec; 37(12):1108-13. doi: 10.1002/j.1552-4604.1997.tb04294.x. [PMID: 9506005]
  • F Scaglione, G De Martini, L Peretto, R Ghezzi, M Baratelli, M M Arcidiacono, F Fraschini. Pharmacokinetic study of cefodizime and ceftriaxone in sera and bones of patients undergoing hip arthroplasty. Antimicrobial agents and chemotherapy. 1997 Oct; 41(10):2292-4. doi: 10.1128/aac.41.10.2292. [PMID: 9333066]
  • C Wenisch, A Bartunek, K Zedtwitz-Liebenstein, M Hiesmayr, B Parschalk, T Pernerstorfer, W Graninger. Prospective randomized comparison of cefodizime versus cefuroxime for perioperative prophylaxis in patients undergoing coronary artery bypass grafting. Antimicrobial agents and chemotherapy. 1997 Jul; 41(7):1584-8. doi: 10.1128/aac.41.7.1584. [PMID: 9210690]
  • Y Mrestani, R Neubert, J Schiewe, A Härtl. Application of capillary zone electrophoresis in cephalosporin analysis. Journal of chromatography. B, Biomedical sciences and applications. 1997 Mar; 690(1-2):321-6. doi: 10.1016/s0378-4347(96)00425-2. [PMID: 9106059]
  • S Nomura, A Kuroiwa, K Murata, A Nagayama. Binding of complement C3 to Klebsiella pneumoniae treated with sub-MIC cefodizime and chemiluminescence response of human polymorphonuclear leukocytes. Chemotherapy. 1997 Mar; 43(2):132-6. doi: 10.1159/000239547. [PMID: 9084922]
  • A Péchinot, C Neuwirth, A Bryskier, J M Duez, A Kazmierczak. Bactericidal activity of cefodizime on Enterobacteriaceae in an in-vitro model simulating plasma pharmacokinetics in humans. The Journal of antimicrobial chemotherapy. 1997 Feb; 39(2):157-62. doi: 10.1093/jac/39.2.157. [PMID: 9069535]
  • M Müller, O Haag, T Burgdorff, A Georgopoulos, W Weninger, B Jansen, G Stanek, H Pehamberger, E Agneter, H G Eichler. Characterization of peripheral-compartment kinetics of antibiotics by in vivo microdialysis in humans. Antimicrobial agents and chemotherapy. 1996 Dec; 40(12):2703-9. doi: 10.1128/aac.40.12.2703. [PMID: 9124826]
  • A C McCafferty, E McGregor, M Jones, I S Henderson, I A Cree. The effect of cefodizime on phagocyte function in non-patient volunteers and patients with chronic renal failure. In vitro and ex vivo studies. International journal of clinical & laboratory research. 1996; 26(4):229-35. doi: 10.1007/bf02602954. [PMID: 9007612]
  • B Lenfant, F Namour, C Logeais, D Coussediere, O Rivault, A Bryskier, A Surjus. Pharmacokinetics of cefodizime following single doses of 0.5, 1.0, 2.0, and 3.0 grams administered intravenously to healthy volunteers. Antimicrobial agents and chemotherapy. 1995 Sep; 39(9):2037-41. doi: 10.1128/aac.39.9.2037. [PMID: 8540712]
  • S Nomura, A Nagayama. In vitro and in vivo enhancement of bactericidal activity of phagocytes against Klebsiella pneumoniae treated with subminimal inhibitory concentrations of cefodizime. Chemotherapy. 1995 May; 41(3):178-86. doi: 10.1159/000239341. [PMID: 7656663]
  • J E Conte. Pharmacokinetics of cefodizime in volunteers with normal or impaired renal function. Journal of clinical pharmacology. 1994 Nov; 34(11):1066-70. doi: 10.1002/j.1552-4604.1994.tb01982.x. [PMID: 7876397]
  • K Matsuura, T Ogata, K Araki, A Kaneko, H Kawasaki, M Kobayashi, I Naoki, T Namikawa, T Andoh, H Yamamoto. [Serum and tissue levels of cefodizime in the pediatric patients]. The Japanese journal of antibiotics. 1994 Aug; 47(8):1071-6. doi: NULL. [PMID: 7933536]
  • Y Yamada, H Fukatsu, A Kamijo, H Mizumoto, T Taki, K Mitsui, H Nonomura, H Ohshita, Y Miyagawa, Y Hatano. [A study of prostatic tissue levels of cefodizime (CDZM)]. Hinyokika kiyo. Acta urologica Japonica. 1994 Apr; 40(4):365-9. doi: NULL. [PMID: 7514846]
  • K Sathirakul, H Suzuki, T Yamada, M Hanano, Y Sugiyama. Multiple transport systems for organic anions across the bile canalicular membrane. The Journal of pharmacology and experimental therapeutics. 1994 Jan; 268(1):65-73. doi: NULL. [PMID: 8301595]
  • Y Pacheco, B Pirollet, B Taviot, B Coppere, M Perrin-Fayolle, E E Dagrosa, D Damm. Concentrations of cefodizime in bronchial secretions after single intravenous administration. Arzneimittel-Forschung. 1993 Aug; 43(8):924-6. doi: NULL. [PMID: 8216455]
  • K Sathirakul, H Suzuki, K Yasuda, M Hanano, O Tagaya, T Horie, Y Sugiyama. Kinetic analysis of hepatobiliary transport of organic anions in Eisai hyperbilirubinemic mutant rats. The Journal of pharmacology and experimental therapeutics. 1993 Jun; 265(3):1301-12. doi: NULL. [PMID: 8510010]
  • K Sathirakul, H Suzuki, K Yasuda, M Hanano, Y Sugiyama. Construction of a physiologically based pharmacokinetic model to describe the hepatobiliary excretion process of ligands: quantitative estimation of intracellular diffusion. Biological & pharmaceutical bulletin. 1993 Mar; 16(3):273-9. doi: 10.1248/bpb.16.273. [PMID: 8364472]
  • S Pruksachatvuthi, N Aswapokee, P Aswapokee. In vitro antimicrobial activity of cefodizime, a third generation cephalosporin. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. 1992 May; 75(5):287-92. doi: NULL. [PMID: 1460409]
  • H Matsushita, H Suzuki, Y Sugiyama, Y Sawada, T Iga, Y Kawaguchi, M Hanano. Effect of benzylpenicillin on the disposition of cefodizime in rats: no net effect on total clearance due to decreased hepatobiliary clearance and increased renal clearance. The Journal of pharmacology and experimental therapeutics. 1992 Feb; 260(2):499-504. doi: NULL. [PMID: 1738099]
  • D Brockmeier, E E Dagrosa. Pharmacokinetic profile of cefodizime. Infection. 1992; 20 Suppl 1(?):S14-7. doi: 10.1007/bf01709944. [PMID: 1526669]
  • I O Auer, C Hardörfer, I Zimmermann. Cefodizime stimulates subpopulations of cells mediating spontaneous or antibody-dependent cytotoxicity in patients with bacterial infections. Infection. 1992; 20 Suppl 1(?):S54-7. doi: 10.1007/bf01709954. [PMID: 1526679]
  • P M Shah, H Knothe. In vivo activity of cefodizime. Infection. 1992; 20 Suppl 1(?):S9-13. doi: 10.1007/bf01709943. [PMID: 1526686]
  • B I Davies, F P Maesen, J J van den Bergh, R J Costongs, W H Geraedts, H L Gubbelmans, J C Meek. Clinical and bacteriological experience with cefodizime in acute purulent exacerbations of chronic bronchitis. Infection. 1992; 20 Suppl 1(?):S22-5. doi: 10.1007/bf01709946. [PMID: 1526671]
  • K Andrassy. Safety profile of cefodizime. Infection. 1992; 20 Suppl 1(?):S36-40. doi: 10.1007/bf01709949. [PMID: 1526675]
  • M el Touny, M el Guinaidy, M Abdel Bary, L Osman, M S Sabbour. Pharmacokinetics of cefodizime in patients with liver cirrhosis and ascites. Chemotherapy. 1992; 38(4):201-5. doi: 10.1159/000239001. [PMID: 1473357]
  • N Itagaki, H Hasegawa, M Sakaguchi, T Oono, I Iwamoto, H Horiuchi, M Tsujino, K Takahashi, A Imada, A Horiuchi. [Pharmacokinetics of cefodizime in patients undergoing hemodialysis]. The Japanese journal of antibiotics. 1991 Dec; 44(12):1392-6. doi: NULL. [PMID: 1798074]
  • H Matsushita, H Suzuki, Y Sugiyama, Y Sawada, T Iga, Y Kawaguchi, M Hanano. Facilitated transport of cefodizime into the rat central nervous system. The Journal of pharmacology and experimental therapeutics. 1991 Nov; 259(2):620-5. doi: NULL. [PMID: 1941610]
  • S Iwata, K Yamada, Y Kin, T Yokota, Y Kusumoto, Y Sato, H Akita, S Nanri, T Oikawa, K Sunakawa. [Influence of cefodizime on intestinal bacterial flora]. The Japanese journal of antibiotics. 1991 Apr; 44(4):412-25. doi: NULL. [PMID: 1880920]
  • H W Asbach. A randomized, dose comparison study of cefodizime in the treatment of lower urinary tract infections in women. Infection. 1991 Mar; 19(2):85-7. doi: 10.1007/bf01645573. [PMID: 2050425]
  • S Esposito, C Sardaro, G B Gaeta, D Galante, G Giusti, F Basani. Cefodizime (HR221) versus norfloxacin for treatment of urinary tract infections. Journal of chemotherapy (Florence, Italy). 1991 Feb; 3(1):42-4. doi: 10.1080/1120009x.1991.11739062. [PMID: 2019862]
  • M A el Guinaidy, S Nawishy, M Abd el Bary, M S Sabbour. Pharmacokinetics of cefodizime in normal individuals and in patients with renal failure. Chemotherapy. 1991; 37(2):77-85. doi: 10.1159/000238837. [PMID: 2032473]
  • R Mazuran, J Tomasić, G Broketa, E Schrinner. Immunophenotypization of cells involved in local immune response and serum antibodies in cephalosporin-treated mice. Drugs under experimental and clinical research. 1991; 17(9):445-50. doi: NULL. [PMID: 1822437]
  • M R Perianu. Clinical safety profile of cefodizime. The Journal of antimicrobial chemotherapy. 1990 Nov; 26 Suppl C(?):127-34. doi: 10.1093/jac/26.suppl_c.127. [PMID: 2074247]
  • J Barré. Pharmacokinetics of cefodizime: a review of the data on file. The Journal of antimicrobial chemotherapy. 1990 Nov; 26 Suppl C(?):95-101. doi: 10.1093/jac/26.suppl_c.95. [PMID: 2074258]
  • A Bryskier, T Procyk, D Tremblay, B Lenfant, J B Fourtillan. Pharmacokinetics of cefodizime administered intravenously as a single-dose (1.0 and 2.0 g) to healthy adult volunteers. The Journal of antimicrobial chemotherapy. 1990 Nov; 26 Suppl C(?):65-70. doi: 10.1093/jac/26.suppl_c.65. [PMID: 2074253]
  • O G Nilsen, F Rennemo, R Rennemo, B Lenfant. Pharmacokinetics of cefodizime in the elderly following single and repeated intravenous administration of 1 g. The Journal of antimicrobial chemotherapy. 1990 Nov; 26 Suppl C(?):71-5. doi: 10.1093/jac/26.suppl_c.71. [PMID: 2074254]
  • A Boccazzi, G Fusi, A M Mezzopane, M Maretti, P Careddu. The pharmacokinetics of cefodizime in children. The Journal of antimicrobial chemotherapy. 1990 Nov; 26 Suppl C(?):83-7. doi: 10.1093/jac/26.suppl_c.83. [PMID: 2074256]
  • P Veyssier, A Devillers, Y Domart, J B Fourtillan, A Bryskier, T Procyk. Pharmacokinetics of cefodizime in elderly patients with moderate or severe renal impairment. The Journal of antimicrobial chemotherapy. 1990 Nov; 26 Suppl C(?):77-81. doi: 10.1093/jac/26.suppl_c.77. [PMID: 2074255]
  • H Matsushita, H Suzuki, Y Sugiyama, Y Sawada, T Iga, M Hanano, Y Kawaguchi. Prediction of the pharmacokinetics of cefodizime and cefotetan in humans from pharmacokinetic parameters in animals. Journal of pharmacobio-dynamics. 1990 Oct; 13(10):602-11. doi: 10.1248/bpb1978.13.602. [PMID: 2095400]
  • T Nishimura, K Tabuki, S Aoki, M Takagi. [Laboratory and clinical studies of cefodizime in pediatric field]. The Japanese journal of antibiotics. 1990 Sep; 43(9):1603-13. doi: NULL. [PMID: 2262965]
  • T Motohiro, Y Yoshinaga, H Sasaki, K Oda, M Aramaki, A Kawakami, K Tanaka, T Koga, Y Shimada, S Tomita. [Influence of cefodizime via intravenous bolus injection on human fecal flora]. The Japanese journal of antibiotics. 1990 Jul; 43(7):1183-213. doi: NULL. [PMID: 2232150]
  • T Motohiro, K Oda, M Aramaki, A Kawakami, K Tanaka, T Koga, Y Sakata, F Yamashita, N Takajo, S Okabayashi. [Experimental and clinical studies on cefodizime in pediatrics]. The Japanese journal of antibiotics. 1990 Apr; 43(4):603-22. doi: NULL. [PMID: 2199688]
  • N Cho, K Fukunaga, K Kunii. [Pharmacokinetic and clinical studies on cefodizime in obstetrics and gynecology]. The Japanese journal of antibiotics. 1989 Oct; 42(10):2069-81. doi: NULL. [PMID: 2607597]
  • K Ito, M Nakagawa, M Mabuchi, T Tamaya, M Hayasaki, Y Yamada, N Ito. [Fundamental and clinical evaluation of cefodizime in obstetrics and gynecology]. The Japanese journal of antibiotics. 1989 Oct; 42(10):2107-19. doi: NULL. [PMID: 2607601]
  • T Yamamoto, J Yasuda, M Kanao, H Okada. [Clinical studies on cefodizime in the field of obstetrics and gynecology]. The Japanese journal of antibiotics. 1989 Oct; 42(10):2121-7. doi: NULL. [PMID: 2607602]
  • Y Kinoshita, S Mizutani, Y Tomoda, T Maruyama, S Hattori, N Mano. [Pharmacokinetic and clinical study on cefodizime in obstetrics and gynecological field]. The Japanese journal of antibiotics. 1989 Oct; 42(10):2090-7. doi: NULL. [PMID: 2607599]
  • B L Lin, Y Iwata. [Pharmacokinetic and clinical studies on cefodizime in the field of obstetrics and gynecology]. The Japanese journal of antibiotics. 1989 Oct; 42(10):2082-9. doi: NULL. [PMID: 2607598]
  • S Arai, S Tabata, S Kobayashi, M Inazu, S Hayashi. Pharmacokinetic study of cefodizime in experimentally infected animals. Arzneimittel-Forschung. 1989 Aug; 39(8):877-82. doi: NULL. [PMID: 2818675]
  • T Haruta, K Okura, S Kuroki, H Yamamoto, Y Kobayashi. [Transferability of cefodizime to cerebrospinal fluid of rabbits with meningitis caused by Staphylococcus aureus]. The Japanese journal of antibiotics. 1989 Jun; 42(6):1279-85. doi: NULL. [PMID: 2795852]
  • Y Nakao, H Takeuchi, H Kimura, H Ishikawa, F Hayakawa, K Kuno. [Laboratory and clinical studies of cefodizime in pediatric field]. The Japanese journal of antibiotics. 1989 Jun; 42(6):1336-45. doi: NULL. [PMID: 2795857]
  • Y Hirabayashi, H Higashino, M Kino, U Nobori, H Okazaki, N Kitamura, Y Kobayashi. [Clinical and pharmacokinetic evaluation of cefodizime in children]. The Japanese journal of antibiotics. 1989 Jun; 42(6):1366-80. doi: . [PMID: 2795860]
  • H Sato, A Narita, K Matsumoto, S Nakazawa, H Suzuki, Y Nakanishi, K Niino, S Nakazawa. [Study on cefodizime, a new cephem antibiotic, in the field of pediatrics]. The Japanese journal of antibiotics. 1989 Jun; 42(6):1306-21. doi: NULL. [PMID: 2795855]
  • M Niino, K Kida, H Matsuda, M Murase. [Clinical studies of cefodizime in the pediatric field]. The Japanese journal of antibiotics. 1989 Jun; 42(6):1400-13. doi: NULL. [PMID: 2795864]
  • H Wakiguchi, T Okada, K Kawai, H Hisakawa, Y Misaki, Y Yamaguchi, I Nomura, H Kubota, T Tomoda, F Hamada. [Therapeutic effects of cefodizime in the treatment of various infectious diseases in children]. The Japanese journal of antibiotics. 1989 Jun; 42(6):1414-23. doi: NULL. [PMID: 2795865]
  • M Yanagishima, M Yanai, T Yanagi, Y Tsuji, H Imamura, N Nakayama. [Laboratory and clinical studies on cefodizime in the pediatric field]. The Japanese journal of antibiotics. 1989 Jun; 42(6):1424-35. doi: NULL. [PMID: 2795866]
  • O Arimasu, H Meguro, F Hiruma, N Sugie, T Abe. [Clinical and pharmacokinetic study on cefodizime, a new cephalosporin antibiotic, in the pediatric infections]. The Japanese journal of antibiotics. 1989 Jun; 42(6):1293-305. doi: NULL. [PMID: 2795854]
  • H Nakamura, M Miyazu, K Kasai, N Iwai, Y Taneda. [Experimental and clinical studies on cefodizime in pediatrics]. The Japanese journal of antibiotics. 1989 Jun; 42(6):1322-35. doi: NULL. [PMID: 2795856]
  • R Fujii, O Arimasu, H Meguro, F Hiruma, N Sugie, T Abe, S Nakazawa, H Sato, A Narita, K Matsumoto. [Pharmacokinetic and clinical studies on cefodizime in the pediatric field. Pediatric Study Group of Cefodizime]. The Japanese journal of antibiotics. 1989 May; 42(5):1173-93. doi: NULL. [PMID: 2664256]
  • H C Korting, A Lukacs, M Schäfer-Korting, E Mutschler. Bactericidal effect of cefodizime against beta-lactamase-producing Neisseria gonorrhoeae in vitro. A comparison of level profiles in serum and tissue after intramuscular and intravenous administration in man. Arzneimittel-Forschung. 1989 Jan; 39(1):31-3. doi: NULL. [PMID: 2497751]
  • F P Maesen, B I Davies, C Baur, C A Sumajow. Cefodizime in acute purulent exacerbations of chronic respiratory disease. The Journal of antimicrobial chemotherapy. 1988 Aug; 22(2):229-35. doi: 10.1093/jac/22.2.229. [PMID: 3182418]
  • N Wada, M Inazu, R Yajima, T Sugisaki, M Miyamoto, T Kobayashi, T Sakaguchi. [Six-month chronic subcutaneous toxicity study of cefodizime sodium in rats]. The Journal of toxicological sciences. 1988 Jun; 13 Suppl 1(?):91-122. doi: 10.2131/jts.13.supplementi_91. [PMID: 3172297]
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