Arsanilic acid (BioDeep_00000412959)

   


代谢物信息卡片


(4-Aminophenyl)arsonic acid

化学式: C6H8AsNO3 (216.9720118)
中文名称: 对氨基苯胂酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1N)[As](=O)(O)O
InChI: InChI=1S/C6H8AsNO3/c8-6-3-1-5(2-4-6)7(9,10)11/h1-4H,8H2,(H2,9,10,11)

描述信息

C254 - Anti-Infective Agent
CONFIDENCE standard compound; INTERNAL_ID 406; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 695; ORIGINAL_PRECURSOR_SCAN_NO 693
CONFIDENCE standard compound; INTERNAL_ID 406; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 691; ORIGINAL_PRECURSOR_SCAN_NO 689
CONFIDENCE standard compound; INTERNAL_ID 406; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 697; ORIGINAL_PRECURSOR_SCAN_NO 693
CONFIDENCE standard compound; INTERNAL_ID 406; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 682; ORIGINAL_PRECURSOR_SCAN_NO 679
CONFIDENCE standard compound; INTERNAL_ID 406; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 702; ORIGINAL_PRECURSOR_SCAN_NO 700
CONFIDENCE standard compound; INTERNAL_ID 406; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 680; ORIGINAL_PRECURSOR_SCAN_NO 677
DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1266; CONFIDENCE standard compound; INTERNAL_ID 406; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; ORIGINAL_PRECURSOR_SCAN_NO 1263
CONFIDENCE standard compound; INTERNAL_ID 406; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1266; ORIGINAL_PRECURSOR_SCAN_NO 1263
CONFIDENCE standard compound; INTERNAL_ID 406; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1267; ORIGINAL_PRECURSOR_SCAN_NO 1263
CONFIDENCE standard compound; INTERNAL_ID 406; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1278; ORIGINAL_PRECURSOR_SCAN_NO 1275
CONFIDENCE standard compound; INTERNAL_ID 406; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1277; ORIGINAL_PRECURSOR_SCAN_NO 1275
CONFIDENCE standard compound; INTERNAL_ID 406; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1272; ORIGINAL_PRECURSOR_SCAN_NO 1269
CONFIDENCE standard compound; INTERNAL_ID 406; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1266; ORIGINAL_PRECURSOR_SCAN_NO 1263

同义名列表

2 个代谢物同义名

Arsanilic acid; (4-Aminophenyl)arsonic acid



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Matheus Sampaio C Barreto, Evert J Elzinga, Donald L Sparks. The adsorption of arsenate and p-arsanilic acid onto ferrihydrite and subsequent desorption by sulfate and artificial seawater: Future implications of sea level rise. Environmental pollution (Barking, Essex : 1987). 2023 Apr; 323(?):121302. doi: 10.1016/j.envpol.2023.121302. [PMID: 36804144]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Yan Ma, Yizhen Shi, Qiujue Wu, Wenfeng Ma. Dietary arsenic supplementation induces oxidative stress by suppressing nuclear factor erythroid 2-related factor 2 in the livers and kidneys of laying hens. Poultry science. 2021 Feb; 100(2):982-992. doi: 10.1016/j.psj.2020.11.061. [PMID: 33518152]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Ning Xie, Na Geng, Dong Zhou, Yuliang Xu, Kangping Liu, Yongxia Liu, Jianzhu Liu. Protective effects of anthocyanin against apoptosis and oxidative stress induced by arsanilic acid in DF-1 cells. Molecular biology reports. 2019 Feb; 46(1):301-308. doi: 10.1007/s11033-018-4472-5. [PMID: 30488373]
  • Anjing Geng, Xu Wang, Lishu Wu, Fuhua Wang, Zhichao Wu, Hui Yang, Yan Chen, Dian Wen, Xiangxiang Liu. Silicon improves growth and alleviates oxidative stress in rice seedlings (Oryza sativa L.) by strengthening antioxidant defense and enhancing protein metabolism under arsanilic acid exposure. Ecotoxicology and environmental safety. 2018 Aug; 158(?):266-273. doi: 10.1016/j.ecoenv.2018.03.050. [PMID: 29715631]
  • Anjing Geng, Xu Wang, Lishu Wu, Fuhua Wang, Yan Chen, Hui Yang, Zhan Zhang, Xiaoli Zhao. Arsenic accumulation and speciation in rice grown in arsanilic acid-elevated paddy soil. Ecotoxicology and environmental safety. 2017 Mar; 137(?):172-178. doi: 10.1016/j.ecoenv.2016.11.030. [PMID: 27936403]
  • Zonglin Yang, Hanyong Peng, Xiufen Lu, Qingqing Liu, Rongfu Huang, Bin Hu, Gary Kachanoski, Martin J Zuidhof, X Chris Le. Arsenic Metabolites, Including N-Acetyl-4-hydroxy-m-arsanilic Acid, in Chicken Litter from a Roxarsone-Feeding Study Involving 1600 Chickens. Environmental science & technology. 2016 07; 50(13):6737-43. doi: 10.1021/acs.est.5b05619. [PMID: 26876684]
  • Mi-Jeong Kwon, Seok-Jin Kang, Young-Il Park, Yool-Hee Yang, Sa-Ik Bang, Yong Ho Park, ByungJae So, Myung-Haing Cho, Hwan-Goo Kang. Hepatic differentiation of human adipose tissue-derived mesenchymal stem cells and adverse effects of arsanilic acid and acetaminophen during in vitro hepatic developmental stage. Cell biology and toxicology. 2015 Jun; 31(3):149-59. doi: 10.1007/s10565-015-9300-2. [PMID: 25894252]
  • Yin Lu, Hui Yuan, Sijun Deng, Qiang Wei, Chengzhi Guo, Jine Yi, Jing Wu, Rongfang Li, Lixin Wen, Zuping He, Liyun Yuan. Arsanilic acid causes apoptosis and oxidative stress in rat kidney epithelial cells (NRK-52e cells) by the activation of the caspase-9 and -3 signaling pathway. Drug and chemical toxicology. 2014 Jan; 37(1):55-62. doi: 10.3109/01480545.2013.806532. [PMID: 23848144]
  • Seok-Jin Kang, Sang-Hee Jeong, Eun-Joo Kim, Young-Il Park, Sung-Won Park, Hyo-Sook Shin, Seong-Wan Son, Hwan-Goo Kang. Toxic effects of methylmercury, arsanilic acid and danofloxacin on the differentiation of mouse embryonic stem cells into neural cells. Journal of veterinary science. 2014; 15(1):61-71. doi: 10.4142/jvs.2014.15.1.61. [PMID: 24136205]
  • Seok-Jin Kang, Sang-Hee Jeong, Eun-Joo Kim, Joon-Hyoung Cho, Young-Il Park, Sung-Won Park, Hyo-Sook Shin, Seong-Wan Son, Hwan-Goo Kang. Evaluation of hepatotoxicity of chemicals using hepatic progenitor and hepatocyte-like cells derived from mouse embryonic stem cells: effect of chemicals on ESC-derived hepatocyte differentiation. Cell biology and toxicology. 2013 Feb; 29(1):1-11. doi: 10.1007/s10565-012-9223-0. [PMID: 23108452]
  • Lixian Yao, Lianxi Huang, Zhaohuan He, Changmin Zhou, Guoliang Li. Occurrence of arsenic impurities in organoarsenics and animal feeds. Journal of agricultural and food chemistry. 2013 Jan; 61(2):320-4. doi: 10.1021/jf3045022. [PMID: 23259671]
  • Uriel Arroyo-Abad, Jürgen Mattusch, Monika Möder, Maria P Elizalde-González, Frank-Michael Matysik. Identification of degradation products of phenylarsonic acid and o-arsanilic acid in contact with suspensions of soils of volcanic origin. Talanta. 2012 Sep; 99(?):310-5. doi: 10.1016/j.talanta.2012.05.057. [PMID: 22967557]
  • Q Desheng, Z Niya. Effect of arsanilic acid on performance and residual of arsenic in tissue of Japanese laying quail. Poultry science. 2006 Dec; 85(12):2097-100. doi: 10.1093/ps/85.12.2097. [PMID: 17135662]
  • Fatih M Uckun, Xing Ping Liu, Osmond J D'Cruz. Human sperm immobilizing activity of aminophenyl arsenic acid and its N-substituted quinazoline, pyrimidine, and purine derivatives: protective effect of glutathione. Reproductive toxicology (Elmsford, N.Y.). 2002 Jan; 16(1):57-64. doi: 10.1016/s0890-6238(01)00195-2. [PMID: 11934532]
  • K L Chen, P W Chiout. Oral treatment of mule ducks with arsenicals for inducing fatty liver. Poultry science. 2001 Mar; 80(3):295-301. doi: 10.1093/ps/80.3.295. [PMID: 11261559]
  • R Hanusová, L Tucková, P Halada, K Bezouska, M Bilej. Peptide fragments induce a more rapid immune response than intact proteins in earthworms. Developmental and comparative immunology. 1999 Mar; 23(2):113-21. doi: 10.1016/s0145-305x(98)00052-4. [PMID: 10227479]
  • M Bilej, L Tucková, A Romanovský. Characterization of the limited specificity of antigen recognition in earthworms. Folia microbiologica. 1995; 40(4):436-40. doi: 10.1007/bf02814753. [PMID: 8763159]
  • J Rejnek, L Tucková, P Síma, M Bilej. The fate of protein antigen in earthworms: study in vivo. Immunology letters. 1993 May; 36(2):131-5. doi: 10.1016/0165-2478(93)90044-3. [PMID: 8349310]
  • M Bilej, P Síma, J Slípka. Repeated antigenic challenge induces earthworm coelomocyte proliferation. Immunology letters. 1992 Apr; 32(2):181-4. doi: 10.1016/0165-2478(92)90112-2. [PMID: 1612641]
  • J de Biasi, L Rekik. Four compartment mammillary model applied to the pharmacokinetics of a spiroarsorane administered orally to rabbits. Journal of biomedical engineering. 1991 Sep; 13(5):439-40. doi: 10.1016/0141-5425(91)90028-6. [PMID: 1795514]
  • L Tucková, J Rejnek, M Bilej, R Pospísil. Characterization of antigen-binding protein in earthworms Lumbricus terrestris and Eisenia foetida. Developmental and comparative immunology. 1991; 15(4):263-8. doi: 10.1016/0145-305x(91)90019-u. [PMID: 1773851]
  • J Rejnek, L Tucková, J Zikán, M Tomana. The interaction of a protein from the coelomic fluid of earthworms with staphylococcal protein A. Developmental and comparative immunology. 1991; 15(4):269-77. doi: 10.1016/0145-305x(91)90020-y. [PMID: 1773852]
  • J B Leikin, R E Goldman-Leikin, M A Evans, S Wiener, D O Hryhorczuk. Immunotherapy in acute arsenic poisoning. Journal of toxicology. Clinical toxicology. 1991; 29(1):59-70. doi: 10.3109/15563659109038598. [PMID: 2005667]
  • M Bilej, L Tuckova, J Rejnek, V Vetvicka. In vitro antigen-binding properties of coelomocytes of Eisenia foetida (Annelida). Immunology letters. 1990 Nov; 26(2):183-7. doi: 10.1016/0165-2478(90)90143-e. [PMID: 2269488]
  • G Dreyfuss, B Penicaut, J G Wolf, G Dubost, J A Nicolas. [Plasma kinetics of a spiroarsorane trypanocidal agent in sheep trypanosomiasis]. Bulletin de la Societe de pathologie exotique (1990). 1990; 83(3):360-6. doi: NULL. [PMID: 2208467]
  • M Bilej, V Vĕtvicka, L Tucková, I Trebichavský, M Koukal, P Síma. Phagocytosis of synthetic particles in earthworms. Effect of antigenic stimulation and opsonization. Folia biologica. 1990; 36(6):273-80. doi: NULL. [PMID: 2279582]
  • L Rekik, Y Coulais, M A Rochas, G Campistron, J G Wolf, G Houin. Pharmacokinetics of two spiroarsoranes administered intravenously or orally to rabbits. Journal of pharmaceutical sciences. 1989 Mar; 78(3):203-5. doi: 10.1002/jps.2600780306. [PMID: 2724078]
  • L Tucková, J Rejnek, P Síma. Response to parenteral stimulation in earthworms L. terrestris and E. foetida. Developmental and comparative immunology. 1988; 12(2):287-96. doi: 10.1016/0145-305x(88)90005-5. [PMID: 3384158]
  • L D Olson. Probable elimination of swine dysentery after feeding ronidazole, carbadox or lincomycin and verification by feeding sodium arsanilate. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 1986 Jul; 50(3):365-8. doi: NULL. [PMID: 3742373]
  • D A Rice, S Kennedy, C H McMurray, W J Blanchflower. Experimental 3-nitro-4-hydroxyphenylarsonic acid toxicosis in pigs. Research in veterinary science. 1985 Jul; 39(1):47-51. doi: 10.1016/s0034-5288(18)31769-7. [PMID: 4035090]
  • C K Li. ELISA-based determination of immunological binding constants. Molecular immunology. 1985 Mar; 22(3):321-7. doi: 10.1016/0161-5890(85)90168-3. [PMID: 4000135]
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  • C C Calvert, L W Smith. Arsenic in tissues of sheep and milk of dairy cows fed arsanilic acid and 3-nitro-4-hydroxyphenylarsonic acid. Journal of animal science. 1980 Aug; 51(2):414-21. doi: 10.2527/jas1980.512414x. [PMID: 7440438]
  • K E Ferslew, G T Edds. Effects of arsanilic acids on growth, serum enzymes, hematologic values, and residual arsenic in young swine. American journal of veterinary research. 1979 Oct; 40(10):1365-9. doi: NULL. [PMID: 43102]
  • V E Jones, S Leskowitz. Immunochemical study of antigenic specificity in delayed hypersensitivity. IV. The production of unresponsiveness to delayed hypersensitivity with a single antigenic determinant. The Journal of experimental medicine. 1965 Sep; 122(3):505-15. doi: 10.1084/jem.122.3.505. [PMID: 5839283]
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  • A V LUISADA-OPPER, H SOBOTKA, J D CHANLEY. Azoproteins. III. Coupling of acetylated bovine serum albumin with arsanilic acid and p-aminobenzoic acid. The Journal of biological chemistry. 1961 Aug; 236(?):2250-3. doi: NULL. [PMID: 13764174]
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