2,2-Dithiobisbenzothiazole (BioDeep_00000412732)
natural product
代谢物信息卡片
化学式: C14H8N2S4 (331.9570328)
中文名称: 二硫化二苯并噻唑
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C2C(=C1)N=C(S2)SSC3=NC4=CC=CC=C4S3
InChI: InChI=1S/C14H8N2S4/c1-3-7-11-9(5-1)15-13(17-11)19-20-14-16-10-6-2-4-8-12(10)18-14/h1-8H
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:53239
- PubChem: 8447
- DrugBank: DB14201
- ChEMBL: CHEMBL508112
- CAS: 120-78-5
- MoNA: CCMSLIB00005724334
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040
. [PMID: 33910017] - Yi-Xiang Xu, Yun-Yuan Huang, Rong-Rong Song, Yan-Liang Ren, Xin Chen, Chao Zhang, Fei Mao, Xiao-Kang Li, Jin Zhu, Shuai-Shuai Ni, Jian Wan, Jian Li. Development of disulfide-derived fructose-1,6-bisphosphatase (FBPase) covalent inhibitors for the treatment of type 2 diabetes.
European journal of medicinal chemistry.
2020 Oct; 203(?):112500. doi:
10.1016/j.ejmech.2020.112500
. [PMID: 32711108] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964
. [PMID: 31515284] - T Sorahan. Cancer risks in chemical production workers exposed to 2-mercaptobenzothiazole.
Occupational and environmental medicine.
2009 Apr; 66(4):269-73. doi:
10.1136/oem.2008.041400
. [PMID: 19158128] - Samir Chahine, Callum Livingstone, James Davis. Solid state differentiation of plasma thiols using a centrifugally activated mercaptobenzothiazole disulfide exchange indicator.
Chemical communications (Cambridge, England).
2007 Feb; ?(6):592-4. doi:
10.1039/b612092j
. [PMID: 17264901] - Larisa O Khoroshko, Varvara N Petrova, Igor V Viktorovskii, Mirja Lahtiperä, Seija Sinkkonen, Jaakko Paasivirta. A wood preservative metabolite in river water.
Environmental science and pollution research international.
2005; 12(1):8-9. doi:
10.1065/espr2004.11.224
. [PMID: 15768735] - E A Emmett, T H Risby, J Taylor, C L Chen, L Jiang, S E Feinman. Skin elicitation threshold of ethylbutyl thiourea and mercaptobenzothiazole with relative leaching from sensitizing products.
Contact dermatitis.
1994 Feb; 30(2):85-90. doi:
10.1111/j.1600-0536.1994.tb00569.x
. [PMID: 8187508] - S M el Dareer, J R Kalin, K F Tillery, D L Hill, J W Barnett. Disposition of 2-mercaptobenzothiazole and 2-mercaptobenzothiazole disulfide in rats dosed intravenously, orally, and topically and in guinea pigs dosed topically.
Journal of toxicology and environmental health.
1989; 27(1):65-84. doi:
10.1080/15287398909531279
. [PMID: 2724369] - J F Redman, N K Bissada. The diagnosis of genitourinary neoplasms.
The Journal of the Arkansas Medical Society.
1975 May; 71(12):393-6. doi:
NULL
. [PMID: 123911]